2025
Perfect health not so perfect after all – a methodological study on patient-reported outcome measures in 2574 patients following percutaneous coronary intervention
Norekvål T, Iversen M, Oterhals K, Allore H, Borregaard B, Pettersen T, Thompson D, Zwisler A, Breivik K. Perfect health not so perfect after all – a methodological study on patient-reported outcome measures in 2574 patients following percutaneous coronary intervention. Health And Quality Of Life Outcomes 2025, 23: 35. PMID: 40188074, PMCID: PMC11972467, DOI: 10.1186/s12955-025-02360-4.Peer-Reviewed Original ResearchConceptsMyocardial Infarction Dimensional Assessment ScaleEQ-5D-5L scoresPatient-reported outcome measuresEQ-5D-5LCeiling effectsOutcome measuresDaily life challengesPicture of patients' health statusHealth statusDisease-specific patient-reported outcome measuresPatient healthBackgroundPatient-reported outcome measuresLatent class analysisHealth utility instrumentsSelf-reported healthPercutaneous coronary interventionPercutaneous coronary intervention centreDisease-specific instrumentPatients' health statusSide effects of medicationsLife challengesEQ-5D-5L descriptive systemSymptoms of fatigueCoronary artery diseaseClass analysis
2024
Impact of Capacity Strain on the Health Status of Patients Discharged From an Intensive Care Unit
Kim S, Pinker E, Rimar J. Impact of Capacity Strain on the Health Status of Patients Discharged From an Intensive Care Unit. Production And Operations Management 2024, 34: 45-59. DOI: 10.1177/10591478241276134.Peer-Reviewed Original ResearchICU capacity strainCapacity strainPatient healthIntensive care unitHealth statusHealth status of patientsQuality of careShorter length of stayLength of stayStatus of patientsPatient dischargeOutcome measuresPatient admissionsTeaching hospitalHealthPatient statusCare unitPost Hoc AnalysisHospitalPost-hocPatientsCareResearch approachUsing Neuromodulators for Salivary, Eccrine, and Apocrine Gland Disorders
Rajanala S, Salame N, Dover J. Using Neuromodulators for Salivary, Eccrine, and Apocrine Gland Disorders. Dermatologic Surgery 2024, 50: s103-s111. PMID: 39196843, DOI: 10.1097/dss.0000000000004262.Peer-Reviewed Original ResearchConceptsQuality of lifeParasympathetic cholinergic neuronsBotulinum toxinLong-term treatmentPatients' quality of lifeTreatment of sialorrheaBotulinum toxin serotype ABotulinum toxin treatmentToxin serotype AImpact patient healthStandard doseGlandular disordersOff-labelOnabotulinumtoxin AIncobotulinumtoxin AAxillary hyperhidrosisNoninvasive treatmentPatient healthApplication of neuromodulationCholinergic neuronsPatients' qualityApocrine glandsHyperhidrosisSerotype BToxin treatmentOrthopaedic Nurse Navigators and Total Joint Arthroplasty Preoperative Optimization
Kebeh M, Dlott C, Kurek D, Morris J, Johnson C, Wiznia D. Orthopaedic Nurse Navigators and Total Joint Arthroplasty Preoperative Optimization. Orthopaedic Nursing 2024, 43: 2-9. PMID: 38266257, PMCID: PMC10832337, DOI: 10.1097/nor.0000000000000997.Peer-Reviewed Original ResearchConceptsNurse navigatorCardiovascular disease managementTotal joint arthroplastyCardiovascular diseaseCoordination of interventionsDisease managementImprove patient healthOptimal diabetesPatient educationPatient healthNursesPreoperative optimization protocolRisk factorsDiabetesCurrent practicesJoint arthroplastyLiterature reviewProgramRiskRecommendationsSurgical outcomesHealthInterventionOrthopaedicsDisease
2022
Gut microbiome dysbiosis in antibiotic-treated COVID-19 patients is associated with microbial translocation and bacteremia
Bernard-Raichon L, Venzon M, Klein J, Axelrad J, Zhang C, Sullivan A, Hussey G, Casanovas-Massana A, Noval M, Valero-Jimenez A, Gago J, Putzel G, Pironti A, Wilder E, Thorpe L, Littman D, Dittmann M, Stapleford K, Shopsin B, Torres V, Ko A, Iwasaki A, Cadwell K, Schluter J. Gut microbiome dysbiosis in antibiotic-treated COVID-19 patients is associated with microbial translocation and bacteremia. Nature Communications 2022, 13: 5926. PMID: 36319618, PMCID: PMC9626559, DOI: 10.1038/s41467-022-33395-6.Peer-Reviewed Original ResearchConceptsGut microbiome dysbiosisCOVID-19 patientsMicrobiome dysbiosisSecondary infectionSARS-CoV-2 infection inducesLife-threatening secondary infectionsTranslocation of bacteriaBlood culture resultsCOVID-19 severityAntimicrobial-resistant speciesCOVID-19Different clinical sitesMicrobial translocationBloodstream infectionsInfection inducesBarrier permeabilitySystemic circulationDysbiosisGoblet cellsPaneth cellsClinical sitesCulture resultsPatient healthGut microbiomePatients
2021
Building a Digital Health Risk Calculator for Older Women with Early-Stage Breast Cancer
Abujarad F, Wang S, Ulrich D, Mougalian S, Killelea B, Fraenkel L, Gross C, Evans S. Building a Digital Health Risk Calculator for Older Women with Early-Stage Breast Cancer. Lecture Notes In Computer Science 2021, 12780: 389-402. DOI: 10.1007/978-3-030-78224-5_27.Peer-Reviewed Original ResearchEarly-stage breast cancerOlder womenBreast cancerRadiation therapyTreatment therapiesEvidence-based treatment decisionsShared-decision modelRisk-benefit informationRisk calculatorRelative riskTreatment decisionsPatient healthDigital health toolsPatient comprehensionTherapyHealth toolsWomenCancerHealthPatientsClinicians
2020
The How Matters
Lee YSH, King MD, Anderson D, Cleary PD, Nembhard IM. The How Matters. Medical Care 2020, 58: 643-650. PMID: 32520838, DOI: 10.1097/mlr.0000000000001342.Peer-Reviewed Original ResearchConceptsPatient healthPrimary care providersQualified health centersDisease managementChronic disease managementPCP participationPatient characteristicsCare teamHealth centersHigher oddsPCP communicationCare providersPatient health managementPatientsHypertensionPractice sitesDisease controlDiabetesElectronic recordsLongitudinal studyMultilevel regression modelsTeam membersRegression modelsHealthPCPToxic Shock Syndrome after Surgery: Case Presentation and Systematic Review of the Literature
Celie KB, Colen DL, Kovach SJ. Toxic Shock Syndrome after Surgery: Case Presentation and Systematic Review of the Literature. Plastic & Reconstructive Surgery Global Open 2020, 8: e2499. PMID: 33133879, PMCID: PMC7572075, DOI: 10.1097/gox.0000000000002499.Peer-Reviewed Original ResearchToxic shock syndromePostoperative toxic shock syndromeShock syndromeSystematic reviewYounger patient ageMeta-Analyses (PRISMA) guidelinesPreferred Reporting ItemsPatient agePermanent complicationsPostoperative patientsSeptic shockPostoperative woundPrompt explorationFatal causeInclusion criteriaIndividual patientsHigh indexReporting ItemsSurgeon awarenessCase presentationPatient healthPatientsSyndromeSurgerySurgeonsDeveloping an Advocacy Curriculum: Lessons Learned from a National Survey of Psychiatric Residency Programs
Vance M, Kennedy K. Developing an Advocacy Curriculum: Lessons Learned from a National Survey of Psychiatric Residency Programs. Academic Psychiatry 2020, 44: 283-288. PMID: 31950369, DOI: 10.1007/s40596-020-01179-z.Peer-Reviewed Original ResearchConceptsAdvocacy curriculumResidency programsPsychiatry residency programsPractice guidelinesBest practice guidelinesMedical professional organizationsPatient healthResidency training programsPsychiatric residency programsPsychiatric residency training programsResidency trainingNational surveyMedical disciplinesAmerican AssociationTraining programPsychiatric residency trainingMedical trainingSemi-structured interviewsPhysiciansProfessional organizations
2019
Clinical management of Type II Diabetes among the unstably housed: a qualitative study of primary care physicians
Henry ML, Lichtman JH, Hanlon K, Keene DE. Clinical management of Type II Diabetes among the unstably housed: a qualitative study of primary care physicians. Family Practice 2019, 37: 418-423. PMID: 31781768, PMCID: PMC7377290, DOI: 10.1093/fampra/cmz085.Peer-Reviewed Original ResearchConceptsType II diabetesPrimary care cliniciansStandard of careII diabetesCare cliniciansDiabetes managementClinical settingPrimary care physiciansOptimal diabetes managementCare physiciansDiabetes patientsType II diabetes managementClinical managementIndividualized carePatient housingUS adultsClinical decisionPatient healthDiabetesPatientsCliniciansCareClinical adjustmentsParticipantsQualitative studyHow Care Coordinators and Other Nursing Professionals Can Help Optimize Care of Asthma in Older Adults
Bernstein C, Tolomeo C. How Care Coordinators and Other Nursing Professionals Can Help Optimize Care of Asthma in Older Adults. 2019, 101-111. DOI: 10.1007/978-3-030-20554-6_9.ChaptersCare coordinatorsOlder adultsCare of asthmaCare coordination supportHealth-related outcomesQuality of lifeImpact asthmaPatient ageAsthma educationCare coordinationChronic illnessClinical pearlsPatients increasesAsthmaPatient healthNursing professionalsVulnerable populationsAdultsAgeIdeal positionHealthPatientsIllnessNursesDisease
2018
Efficacy and unintended consequences of hard-stop alerts in electronic health record systems: a systematic review
Powers EM, Shiffman RN, Melnick ER, Hickner A, Sharifi M. Efficacy and unintended consequences of hard-stop alerts in electronic health record systems: a systematic review. Journal Of The American Medical Informatics Association 2018, 25: 1556-1566. PMID: 30239810, PMCID: PMC6915824, DOI: 10.1093/jamia/ocy112.Peer-Reviewed Original ResearchConceptsHealth outcomesAssociated health outcomesGrey literature sitesAdverse eventsElectronic health record systemsDelivery outcomesClinical problemReference listsHealth record systemsHealthcare delivery outcomesSystematic reviewProcess outcomesPatient healthHealthcare settingsHard stopAlert frequencyOutcomesRecord systemScience databases
2017
Reductions in Readmission Rates Are Associated With Modest Improvements in Patient-reported Health Gains Following Hip and Knee Replacement in England
Friebel R, Dharmarajan K, Krumholz HM, Steventon A. Reductions in Readmission Rates Are Associated With Modest Improvements in Patient-reported Health Gains Following Hip and Knee Replacement in England. Medical Care 2017, 55: 834-840. PMID: 28742545, PMCID: PMC5555974, DOI: 10.1097/mlr.0000000000000779.Peer-Reviewed Original ResearchConceptsRisk-adjusted readmission ratesReadmission ratesEQ-VASHealth gainsEQ-5DKnee replacementHip replacementOxford Hip ScoreOxford Knee ScorePatient-reported healthPatient-reported outcomesVisual analog scaleKnee replacement surgeryReadmission reduction initiativesHealth care systemAdditional health gainsHip scoreKnee scoreAnalog scalePresurgical assessmentReplacement surgeryPatients' senseHospital groupModest ImprovementPatient healthNICH at Its Best for Diabetes at Its Worst: Texting Teens and Their Caregivers for Better Outcomes
Wagner D, Barry S, Stoeckel M, Teplitsky L, Harris M. NICH at Its Best for Diabetes at Its Worst: Texting Teens and Their Caregivers for Better Outcomes. Journal Of Diabetes Science And Technology 2017, 11: 468-475. PMID: 28745094, PMCID: PMC5505437, DOI: 10.1177/1932296817695337.Peer-Reviewed Original ResearchConceptsHealth outcomesPatient healthProgram involvementHealth outcome dataText-based interventionImprove patient healthAssociated health outcomesHealth care costsPersonalized text messagesPatients' caregiversAssociated with improvementsYouth healthCare costsBetter outcomesCaregiversProgram enrollmentNICHE programText messagesSMS useNiche participateNovel interventionsHealthHigh-risk youthChildren's HealthcareType 1 diabetes
2016
Lobectomy versus stereotactic body radiotherapy in healthy patients with stage I lung cancer
Rosen JE, Salazar MC, Wang Z, Yu JB, Decker RH, Kim AW, Detterbeck FC, Boffa DJ. Lobectomy versus stereotactic body radiotherapy in healthy patients with stage I lung cancer. Journal Of Thoracic And Cardiovascular Surgery 2016, 152: 44-54.e9. PMID: 27131846, DOI: 10.1016/j.jtcvs.2016.03.060.Peer-Reviewed Original ResearchConceptsStage I lung cancerStereotactic body radiotherapyI lung cancerNational Cancer DatabaseClinical stage I lung cancerNon-small cell lung cancerCell lung cancerBody radiotherapyHealthy patientsLung cancerCancer DatabaseClinical stage I non-small cell lung cancerStage I non-small cell lung cancerBetter outcomesEarly-stage non-small cell lung cancerPatient healthCox proportional hazards modelComorbidity-free patientsClinical stage IPropensity-matched analysisProportional hazards modelLong-term survivalHealth-related reasonsStereotactic patientsT1N0M0 tumors
2015
Tumor profiling and the incidentalome: patient decisions and risks
Hofstatter E, Mehra K, Yushak M, Pusztai L. Tumor profiling and the incidentalome: patient decisions and risks. Future Oncology 2015, 11: 3299-3305. PMID: 26562094, DOI: 10.2217/fon.15.260.BooksConceptsTumor profilingField of oncologyTumor DNA sequencesOncology patientsIncidental discoveryPatient educationPatient's perspectivePatient decisionOncology communityClinical implicationsPatient healthGermline mutationsCancer medicineGenetic sequencingCancer therapyTherapyPotential riskRiskHealthPatientsIncidentalomeMainstayDiseaseOncologyProfiling
2010
Causes and Consequences of Inadequate Management of Acute Pain
Sinatra R. Causes and Consequences of Inadequate Management of Acute Pain. Pain Medicine 2010, 11: 1859-1871. PMID: 21040438, DOI: 10.1111/j.1526-4637.2010.00983.x.Peer-Reviewed Original ResearchConceptsInadequate pain managementAcute painPain managementTolerability balanceChronic painMultimodal therapyIntense acute painSingle-agent regimensAcute pain managementSevere acute painCurrent practice guidelinesMillions of patientsAgent regimensMultiple analgesicsAnalgesic therapyPain controlAvailable therapiesClinical effectivenessPreferred treatmentPractice guidelinesUndermanaged painEffective treatmentPainSide effectsPatient health
2009
The Experience of Discrimination and Black-White Health Disparities in Medical Care
Penner L, Dovidio J, Edmondson D, Dailey R, Markova T, Albrecht T, Gaertner S. The Experience of Discrimination and Black-White Health Disparities in Medical Care. Journal Of Black Psychology 2009, 35: 180-203. PMID: 24347741, PMCID: PMC3862356, DOI: 10.1177/0095798409333585.Peer-Reviewed Original ResearchPatient healthPhysician recommendationBlack patientsPrimary care clinicsLow socioeconomic statusBlack-white health disparitiesCare clinicsOverall healthPatient reactionsMedical careHealth disparitiesPast adherencePatientsRacial disparitiesSocioeconomic statusCurrent healthAdherenceMedical interactionsHealthPhysiciansCurrent studyExperiences of discriminationClinicDisparitiesVisits
2005
Sleep disorders in older people
Banno K, Kryger M. Sleep disorders in older people. Aging Health 2005, 1: 449-457. DOI: 10.2217/1745509x.1.3.449.Peer-Reviewed Original ResearchSleep disordersObstructive sleep apnea syndromeOlder peopleAge-related medical conditionsSleep apnea syndromeRestless legs syndromeFrequent nocturnal awakeningsCommon sleep disorderQuality of lifeSleep onset insomniaObstructive sleepApnea syndromeNeuropsychiatric functionRestless legsLegs syndromeImpaired qualityNocturnal awakeningsUpper airwayAnatomic changesCognitive dysfunctionMedical conditionsSleep pathologyPsychiatric conditionsNeuropsychiatric disordersPatient health
1997
Issues Regarding Antiretroviral Treatment for Patients With HIV-1 Infection
Ickovics J, Chesney M. Issues Regarding Antiretroviral Treatment for Patients With HIV-1 Infection. JAMA 1997, 278: 1233-1234. PMID: 9333258, DOI: 10.1001/jama.1997.03550150037025.Peer-Reviewed Original ResearchConceptsAdherence behaviorPlasma human immunodeficiency virus (HIV) RNA levelsHuman immunodeficiency virus (HIV) RNA levelsDrug resistanceVirus RNA levelsHIV-1 infectionDrug regimenHIV diseaseAntiretroviral treatmentViral loadTreatment regimensCombination therapyPatients' willingnessDisease progressionCostly regimensConsensus statementMore pillsPatient healthRegimensRNA levelsAdherenceDearth of informationTherapyBrief periodNonadherence
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