2025
Causal Mediation Analysis for the Intergenerational Transmission of Violence Reveals Pathways From Child Maltreatment to Elder Mistreatment
Pickering C, Yildiz M, Browning W, Chilatra J, Yefimova M, Maxwell C, Sullivan T. Causal Mediation Analysis for the Intergenerational Transmission of Violence Reveals Pathways From Child Maltreatment to Elder Mistreatment. The Gerontologist 2025, 65: gnaf132. PMID: 40244912, PMCID: PMC12129107, DOI: 10.1093/geront/gnaf132.Peer-Reviewed Original ResearchConceptsChild maltreatment victimsMaltreatment victimsElder mistreatmentIntergenerational transmissionIntergenerational transmission of violenceMediation modelFamily caregiversTransmission of violenceLife course trajectoriesChild maltreatment historyLife course viewTrajectories of familiesSerial mediation modelDementia family caregiversEarly-life experiencesFamily caregiver roleChild maltreatmentEmotion dysregulationEmotional processingAttribution biasMaltreatment historyCausal mediation analysisObservational longitudinal studyCognitive processesMediation analysisQualitative evaluation of meaningful change in Dravet syndrome as measured by the Vineland-3: Caregiver and clinician perspectives
Condon C, Parkerson K, Dandurand A, Wang F, Howse C, Mayhew M, Whyman S, Ventola P, Anne Meskis M, Sullivan J, Knupp K, Gater A, Mahon-Smith A. Qualitative evaluation of meaningful change in Dravet syndrome as measured by the Vineland-3: Caregiver and clinician perspectives. Epilepsy & Behavior 2025, 167: 110381. PMID: 40188607, DOI: 10.1016/j.yebeh.2025.110381.Peer-Reviewed Original ResearchConceptsVineland-3Presence of autism spectrum disorderVineland Adaptive Behavior ScalesAdaptive Behavior ScalesAutism spectrum disorderDravet syndromeCaregivers of children/adolescentsDisruptive behaviorSpectrum disorderBehavior ScaleClinical expertsClinically meaningful changeAdaptive behaviorReceptive communicationImpaired communicationThird editionAnchor-based methodsSemi-structured interviewsTreatment-related benefitsCaregiver feedbackClinician perspectivesMeaningful changePatient independenceCaregiversQualitative studyAlcohol Use and Abusive or Neglectful Behaviors Among Family Caregivers of Patients With Dementia
Chilatra J, Browning W, Yildiz M, Yefimova M, Maxwell C, Sullivan T, Pickering C. Alcohol Use and Abusive or Neglectful Behaviors Among Family Caregivers of Patients With Dementia. JAMA Network Open 2025, 8: e256211. PMID: 40261656, PMCID: PMC12015665, DOI: 10.1001/jamanetworkopen.2025.6211.Peer-Reviewed Original ResearchConceptsFamily caregivers of relativesCaregivers of relativesFamily caregiversAssociated with increased oddsCare recipientsHazardous drinkingDaily alcohol consumptionAlcohol useDaily alcohol useSample of family caregiversFamily caregivers of patientsIncreasing prevalence of dementiaAlcohol consumptionAlcohol use patternsCaregivers of patientsPrevalence of dementiaCommunity-dwelling relativeAssociated with higher oddsNeglectful behaviorsAssociated with greater oddsBaseline hazardous drinkingBaseline surveyUnpaid careLinear mixed modelsMain OutcomesPost–Intensive Care Syndrome and Caregiver Burden
Ahn S, LaNoue M, Su H, Moale A, Scheunemann L, Kiehl A, Douglas I, Exline M, Gong M, Khan B, Owens R, Pisani M, Rock P, Jackson J, Ely E, Girard T, Boehm L. Post–Intensive Care Syndrome and Caregiver Burden. JAMA Network Open 2025, 8: e253443. PMID: 40198074, PMCID: PMC11979734, DOI: 10.1001/jamanetworkopen.2025.3443.Peer-Reviewed Original ResearchConceptsPost-intensive care syndromeCaregiver burdenIntensive care unitKatz activities of daily livingTelephone Interview for Cognitive StatusSecondary analysisActivities of daily livingPatient-caregiver dyadsZarit Burden InterviewRandomized clinical trialsIntensive care unit survivorsFunctional Activities QuestionnairePosttraumatic Stress Disorder Checklist-Civilian VersionIntensive care unit deliriumCare of patientsAcademic medical centerOptimal care of patientsChecklist-Civilian VersionBurden InterviewActivity QuestionnaireKatz ActivitiesDaily livingFollow-upICU survivorsMain OutcomesPatients' and Caregivers' Perspectives on the Role of Ambulatory Specialty Palliative Care for People With Heart Failure
Lendvai D, Zhan Y, Kavalieratos D, Iannone L, Akgün K, Allen L, Bekelman D, Ersek M, Goldstein N, Luhrs C, Feder S. Patients' and Caregivers' Perspectives on the Role of Ambulatory Specialty Palliative Care for People With Heart Failure. Journal Of Pain And Symptom Management 2025, 70: 89-105. PMID: 40147501, PMCID: PMC12148689, DOI: 10.1016/j.jpainsymman.2025.02.019.Peer-Reviewed Original ResearchConceptsSpecialist palliative carePalliative careCompletion of advance directivesSpecialist palliative care teamsDiscussion of goals of careDepartment of Veterans Affairs (VAVeterans Affairs (VASpecialty palliative careGoals of careHigh-quality careSurrogate decision-makersBarriers to engagementQualitative descriptive studyFamily caregiversCare coordinationCardiology cliniciansIllness conversationsCaregiver perspectivesAdvance directivesDescriptive studyHealthcare systemCaregiversAmbulatory settingCareHeart failure“Can I afford to live today?” The emotional toll of navigating the healthcare system with type 1 diabetes
Harel S, Lukasik J, Wilcox A, Lipska K, Weinzimer S, Suttiratana S, Nally L. “Can I afford to live today?” The emotional toll of navigating the healthcare system with type 1 diabetes. Frontiers In Endocrinology 2025, 16: 1555265. PMID: 40196455, PMCID: PMC11973976, DOI: 10.3389/fendo.2025.1555265.Peer-Reviewed Original ResearchConceptsHealthcare systemDiabetes managementBurden of managing diabetesType 1 diabetesSelf-reported useTranscripts of semi-structuredFeelings of powerlessnessQuality of lifeFear of health problemsDaily diabetes managementDefinition of themesDiabetes supportStudy of individualsChild healthDiabetes suppliesTelephone interviewsDiabetes medicationsEmotional tollSemi-structuredHealth problemsFinancial burdenHealthcarePWDParticipantsDiabetesHealth System, Community-Based, or Usual Dementia Care for Persons With Dementia and Caregivers
Reuben D, Gill T, Stevens A, Williamson J, Volpi E, Lichtenstein M, Jennings L, Galloway R, Summapund J, Araujo K, Bass D, Weitzman L, Tan Z, Evertson L, Yang M, Currie K, Green A, Godoy S, Abraham S, Reese J, Samper-Ternent R, Hirst R, Borek P, Charpentier P, Meng C, Dziura J, Xu Y, Skokos E, He Z, Aiudi S, Peduzzi P, Greene E, Serrano K, Unger E, Arruda L, Bautista L, Callahan C, Maslow K, Ling S, Bonner A, Pace D, Cherry D, Kremer I, Nicholson B, Stephens C, Hendler R, Carnie M, Shelton A, Mignosa B, Funaro B, Eisenmann K, Lu C, Chattopadhyay S, Rhoades D, Lakomski A, Maher D, McCurry D, Williamson S, Moyer S, Robertson L, Tilles A, Battle L, Walker W, Levine S, Knight G, Eaton A, Rose T, Weston E, Orr B, Lang S, Rinaldi S, Shore J, Garboczi L, Phoenix K, Mitchell M, Levan L, Layza M, Musgrave D, Silverman J, Martin A, Nienstedt J, Handoo R, Woolard N, Burcombe D, Hutchens C, Sanghi S, Ocloo A, Essiet S, Shah M, Bartosh H, Banda J, Birchfield T, Roznos T, Collins B, Parker D, Matlock M, Drew L, Jones T, Hill B, Walker J, Wills J, Andrews M, Kroloff S, Brown G, Franz C, Perez G, Castillo E, Flores C, Raji M, Martinez E, Skinkis P, Williams A, Minello S, Sherrod J, Odejimi A, Lockhart M, McDonald A, Gibson D, Tobias N, Spetter K, Finney G, Ladd I, Weaver K, Nicoletto P, Smith D, DeLucca R, Delmar N, Dopko J, Patel M, Berry P, Zimmerman K, Fasciana J, Hendricks L, Freedman K, Gudonis S, Drutarovsky H, Gurzynski A, Shillabeer M, Shipsky K, Cannon C, Rahm A, Sharf L, Kearney K, Liu J, Keeler E, Ruder T. Health System, Community-Based, or Usual Dementia Care for Persons With Dementia and Caregivers. JAMA 2025, 333: 950-961. PMID: 39878968, PMCID: PMC11780506, DOI: 10.1001/jama.2024.25056.Peer-Reviewed Original ResearchConceptsCommunity-based careModified Caregiver Strain IndexHealth system-basedCaregiver Strain IndexCaregiver self-efficacyUsual careDementia careHealth systemCommunity-BasedNPI-QPrimary outcomeApproaches to dementia careCommunity-based dementia careCommunity-based care interventionsSelf-EfficacyDementia care programDementia care specialistsSecondary outcomesStrain indexSystem-based careCommunity-dwelling personsNeuropsychiatric Inventory QuestionnairePatient behavioral symptomsNPI-Q scoresCaregiver outcomesDevelopment and evaluation of a healthcare decision-making intervention for African American parent-adult daughter dementia dyads: a mixed-methods study protocol
Johnson K, Lyons K, Epps F, Daniel G, Monin J, Powell W, Hepburn K. Development and evaluation of a healthcare decision-making intervention for African American parent-adult daughter dementia dyads: a mixed-methods study protocol. BMJ Open 2025, 15: e099976. PMID: 40081986, PMCID: PMC11906994, DOI: 10.1136/bmjopen-2025-099976.Peer-Reviewed Original ResearchConceptsQuality of lifeDementia dyadsPrototype interventionQualitative data collectionQuantitative data collectionOlder adultsMixed-methods study protocolNon-Hispanic White older adultsAfrican American older adultsSelf-EfficacyPretest-post-test designWhite older adultsAmerican older adultsDecision-making interventionsHealth-related decisionsSequential mixed-methods designUniversity Institutional Review BoardPrevalence of Alzheimer's diseaseAfrican American personsData collectionExplanatory sequential mixed-methods designMixed-methods designRandomised controlled trialsCare partnersIntervention MappingBurden and care time for dementia caregivers in the LIVE@Home.Path trial
Berge L, Angeles R, Gedde M, Fæø S, Mannseth J, Vislapuu M, Puaschitz N, Hillestad E, Aarsland D, Achterberg W, Allore H, Ballard C, Li F, Selbæk G, Vahia I, Husebo B. Burden and care time for dementia caregivers in the LIVE@Home.Path trial. Alzheimer's & Dementia 2025, 21: e14622. PMID: 40042468, PMCID: PMC11881633, DOI: 10.1002/alz.14622.Peer-Reviewed Original ResearchConceptsRelative Stress ScaleInformal care timeCaregiver burdenLiving interventionsCare timeIntervention periodStepped wedge randomized controlled trialVolunteer supportHome-dwelling peopleStepped-wedge trialPersonal activitiesDementia caregiversRandomized Controlled TrialsIntention-to-treatStress ScaleMunicipal coordinatorCaregiversPersonal supportRandomized dyadsDementiaControlled TrialsPrimary outcomeControl periodInterventionPositive changesCare Recipients’ Cognitive Trajectories and Caregivers’ Depressive Symptoms: The Mediating Role of Caregiving Burden
Lou Y, Gong J, Zang E. Care Recipients’ Cognitive Trajectories and Caregivers’ Depressive Symptoms: The Mediating Role of Caregiving Burden. The Gerontologist 2025, 65: gnaf024. PMID: 39873410, PMCID: PMC11934274, DOI: 10.1093/geront/gnaf024.Peer-Reviewed Original ResearchConceptsCaregiver depressive symptomsCare recipientsCaregiver burdenDepressive symptomsCognitive trajectoriesCaregiving burdenNational Health and Aging Trends StudyNational Study of CaregivingFinancial caregiving burdensCaregiver mental healthStudy of CaregivingStress process modelLongitudinal cognitive courseGroup-based trajectoryCaregiving difficultiesCaregiving experienceTrajectory group membershipEmotional burdenTrends StudyMental healthCaregiversCareTrajectory groupsNational studyCognitive functionProtocol of a decisional intervention for older adults with newly diagnosed acute myeloid leukemia and their caregivers: UR-GOAL 3
Loh K, Ng Q, Mohile S, Norton S, Epstein R, Sohn M, Richardson D, Jamy O, Hedjri S, Blumberg R, Nafis L, Jensen-Battaglia M, Wang Y, Mendler J, Liesveld J, Huselton E, Rodenbach R, Moore J, Maguire C, Buechler S, Hodges S, Klepin H. Protocol of a decisional intervention for older adults with newly diagnosed acute myeloid leukemia and their caregivers: UR-GOAL 3. Journal Of Geriatric Oncology 2025, 16: 102187. PMID: 39828449, PMCID: PMC11890953, DOI: 10.1016/j.jgo.2025.102187.Peer-Reviewed Original ResearchConceptsShared decision makingDecisional conflictOlder adultsAging-related conditionsOutcome measuresGoal-concordant careEducational videosAssociated with poor qualityPerceptions of prognosisReduce patient distressLife-prolonging treatmentIncreased healthcare utilizationSecondary outcome measuresAcute myeloid leukemiaValues clarification processRandomized Controlled TrialsDistress ThermometerMulticenter randomized controlled trialPrimary outcome measureTreatment decisionsCaregiver distressHealthcare utilizationReduce distressPatient distressPsychological distress
2024
Navigating life after New-onset refractory status epilepticus (NORSE) and Febrile infection-related epilepsy syndrome (FIRES): Insights from caregiver and patient interviews
Eschbach K, Reedy J, Gofton T, Gopaul M, Farias-Moeller R, Kellogg M, Knupp K, Hirsch L, Wong N, Dorsey Holliman B. Navigating life after New-onset refractory status epilepticus (NORSE) and Febrile infection-related epilepsy syndrome (FIRES): Insights from caregiver and patient interviews. Epilepsy & Behavior 2024, 163: 110236. PMID: 39740258, DOI: 10.1016/j.yebeh.2024.110236.Peer-Reviewed Original ResearchConceptsQuality of lifeCaregivers' quality of lifeDyadic semi-structured interviewsEmotional quality of lifeThematic content analysis approachComorbid health concernsHealth concernBehavioral health concernsContent analysis approachSignificant life changesMedication side effectsSemi-structured interviewsPatients' quality of lifeRisk of mortalityLife-altering impactPatient interviewsPatient independenceCaregiversNeurologically healthy individualsLife changesNew-onset refractory status epilepticusImpact patients' quality of lifeFebrile infection-related epilepsy syndromeFamily membersLong-term impactDelays in Care for Children With Low Anorectal Malformations in Southwestern Uganda
Oyania F, Stephens C, Ullrich S, Kotagal M, Kisitu D, Bajunirwe F, Ozgediz D, Poenaru D. Delays in Care for Children With Low Anorectal Malformations in Southwestern Uganda. Journal Of Surgical Research 2024, 305: 156-162. PMID: 39700891, PMCID: PMC11779581, DOI: 10.1016/j.jss.2024.11.013.Peer-Reviewed Original ResearchConceptsReceive careHealth-care system factorsHealth-care workers knowledgeSouthwestern UgandaPrimary health-care providersLow anorectal malformationImproving referral processesHealth-care providersCross-sectional studyDelayed DiagnosisAnorectal malformationsReaching careLow-income countriesSeeking CareReferral processHealth centersWorkers' knowledgeChild's diseaseScreening examinationHealth insurance policiesCareCaregiversSystemic factorsFinancial problemsStatistical significanceThe effects of a psychoeducational intervention on caregivers of colorectal cancer patients: A meta-analysis of randomized controlled trials
Zhang M, Xue Y, Shao M, Yang Y, Yu L, Ma B, Li D, Zhou H, Wang K, Chen C, Cheng M, Wang T. The effects of a psychoeducational intervention on caregivers of colorectal cancer patients: A meta-analysis of randomized controlled trials. European Journal Of Oncology Nursing 2024, 74: 102739. PMID: 39729814, DOI: 10.1016/j.ejon.2024.102739.Peer-Reviewed Original ResearchConceptsPsychoeducational interventionRandomized Controlled TrialsPsychological statusImpact of psychoeducational interventionsAspects of caregivingReduce caregiver burdenControlled TrialsEnhancing caregivers' abilityCondition of caregiversImprove quality of lifeQuality of lifeCaregiver burdenCRC patientsRandom-effects modelCaregivers' abilityCINAHL CompletePerception of family supportGeneral well-beingActive lifestyleWeb of ScienceMeta-analysis of randomized controlled trialsPhysical healthCare scheduleSocial supportFixed-effects modelMechanisms Underlying the Use of Abusive and Neglectful Behaviors in Dementia Caregiving: The Role of Caregiver Mental Health.
Browning W, Yildiz M, Hernandez Chilatra J, Yefimova M, Maxwell C, Sullivan T, Winstead V, Pickering C. Mechanisms Underlying the Use of Abusive and Neglectful Behaviors in Dementia Caregiving: The Role of Caregiver Mental Health. Research In Gerontological Nursing 2024, 17: 227-236. PMID: 39347758, DOI: 10.3928/19404921-20240808-01.Peer-Reviewed Original ResearchConceptsCaregiver mental healthFamily caregiversAssociated with increased oddsAnxiety disordersCare recipientsMental healthNeglectful behaviorsAnxiety symptomsFamily caregiver populationDementia family caregiversImpact of caregivingAnxiety symptom severityClinically significant depressionGeneralized anxiety disorderMental health symptomologyWorsening anxiety symptomsWorsening depressive symptomsIntensive longitudinal designPhysically aggressive behaviorDementia caregiversCaregiver populationCaregiver psychopathologyLinear mixed modelsSignificant interaction effectCaregiversPost-traumatic stress disorder symptoms following exposure to acute psychological trauma in children aged 8–16 years in South Africa: protocol for the Sinethemba longitudinal study
Sharp T, Chideya Y, Giuliani A, Hunt X, Tomlinson M, Seedat S, Creswell C, Fearon P, Hamilton-Giachritsis C, Hiller R, Meiser-Stedman R, Du Toit S, Stewart J, Halligan S. Post-traumatic stress disorder symptoms following exposure to acute psychological trauma in children aged 8–16 years in South Africa: protocol for the Sinethemba longitudinal study. BMJ Open 2024, 14: e085129. PMID: 38991675, PMCID: PMC11624694, DOI: 10.1136/bmjopen-2024-085129.Peer-Reviewed Original ResearchConceptsMental health outcomesPost-traumatic stress disorderChildren aged 8Caregiver supportHealth outcomesAssociation of psychosocial factorsAdverse mental health outcomesAged 8Traumatic eventsChildren’s post-traumatic stress disorderDepartment of HealthMiddle-income countriesTrauma-related mental healthPsychological risk factorsHigh-income countriesStress disorder symptomsFollow-up assessmentPost-traumatic stress disorder symptomsCape TownMotor vehicle accidentsHealthcare clinicsPsychosocial factorsMental healthPsychological recoveryEthical approvalMultimorbidity and associated informal care receiving characteristics for US older adults: a latent class analysis
Liu R, Nagel C, Chen S, Newsom J, Allore H, Quiñones A. Multimorbidity and associated informal care receiving characteristics for US older adults: a latent class analysis. BMC Geriatrics 2024, 24: 571. PMID: 38956501, PMCID: PMC11221032, DOI: 10.1186/s12877-024-05158-z.Peer-Reviewed Original ResearchConceptsNational Health and Aging Trends StudyMultimorbidity patternsCare needsOlder adultsSelf-CareInformal careLatent class analysisCare receiver characteristicsCombinations of multimorbidityPerson-centered carePatterns of multimorbidityDifferential care needsUS older adultsAssociated with lower oddsAssociated with higher oddsGroup of older adultsMultinomial logistic regression modelModerate cognitive impairmentClass analysisLogistic regression modelsInformal caregiversBackgroundOlder adultsCare recipientsMultimorbidity groupsChronic conditions“WOOP is my safe haven”: A qualitative feasibility and acceptability study of the Wish Outcome Obstacle Plan (WOOP) intervention for spouses of people living with early‐stage dementia
Mroz E, Schwartz A, Valeika S, Oettingen G, Marottoli R, David D, Hagaman A, Fedus D, Monin J. “WOOP is my safe haven”: A qualitative feasibility and acceptability study of the Wish Outcome Obstacle Plan (WOOP) intervention for spouses of people living with early‐stage dementia. International Journal Of Geriatric Psychiatry 2024, 39: e6092. PMID: 38687142, PMCID: PMC11448666, DOI: 10.1002/gps.6092.Peer-Reviewed Original ResearchConceptsSpouses of peopleLongitudinal semi-structured interviewsEarly-stage dementiaCodebook thematic analysisSemi-structured interviewsCare partnersIntervention deliveryBaseline strengthThematic analysisMeta-themesQualitative studyBehavioral interventionsAreas of improvementDementiaQualitative feasibilityMental exerciseInterventionSpousesWell-beingEmotional stressorsIntervention mechanismsParticipantsAcceptability studyWishesPeopleThe Impact on Families of Children With Congenital Upper Extremity Differences
Ballatori S, Bauer A, Wang A, Samora J, Steinman S, Manske C, Shah A, Wall L, Group C. The Impact on Families of Children With Congenital Upper Extremity Differences. The Journal Of Hand Surgery 2024, 49: 681-689. PMID: 38639681, DOI: 10.1016/j.jhsa.2024.02.011.Peer-Reviewed Original ResearchConceptsPatient-Reported Outcomes Measurement Information SystemPediatric Outcomes Data Collection InstrumentUpper extremity involvementPatient-Reported Outcomes Measurement Information System Upper ExtremityPROMIS Pain InterferenceOutcomes Measurement Information SystemExtremity involvementBrachial plexus birth injuryCongenital upper limb differencesCaregivers of patientsPatient-reported outcome measuresCaregivers of childrenMeasurement Information SystemUpper limb differencesCross-sectional studyAt-risk familiesMusculoskeletal diagnosesCaregiver strainPain interferenceTYPE OF STUDY/LEVELCerebral palsyLimb differencesData collection instrumentFamily impactBirth injuryFinancial Health Is Health: Addressing Acute and Chronic Financial Stress Across the Care Spectrum.
Rosenberg J, Sude L. Financial Health Is Health: Addressing Acute and Chronic Financial Stress Across the Care Spectrum. Hospital Pediatrics 2024, 14: e212-e214. PMID: 38495027, PMCID: PMC10965755, DOI: 10.1542/hpeds.2023-007601.Peer-Reviewed Original Research
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