2025
Diverging paths: Identifying barriers to and increasing accessibility of a survivorship program in a socio-economically diverse community.
Thau F, Madrid K, Smith N, Gambaccini M, Sanft T, Capozza S. Diverging paths: Identifying barriers to and increasing accessibility of a survivorship program in a socio-economically diverse community. Journal Of Clinical Oncology 2025, 43 DOI: 10.1200/jco.2025.43.16_suppl.e13877.Peer-Reviewed Original ResearchMedian household incomeSurvivorship programsClinical sitesHousehold incomeSurvivorship clinic visitLife of cancer survivorsNo-showLow median household incomePatient's zip codeIn-Person VisitsArea of residenceDiverse patient groupsElectronic medical recordsScheduled patient visitsState-based insuranceDiverse patient populationsCancer survivorsIdentified barriersHome addressPatient visitsScheduling appointmentsZip codesIn-personQualitative studyDemographics of patientsSerum chloride and the response to combining loop and thiazide diuretics for acute heart failure: the ALCALOTIC study
Núñez J, Miñana G, Villalonga M, Asenjo M, Carrera M, Epelde F, Gil M, Chivite D, Contra A, Pla X, Casado J, Miró Ò, de la Espriella R, Testani J, Trullàs J. Serum chloride and the response to combining loop and thiazide diuretics for acute heart failure: the ALCALOTIC study. Internal And Emergency Medicine 2025, 1-11. PMID: 40379935, DOI: 10.1007/s11739-025-03961-z.Peer-Reviewed Original ResearchAcute heart failureHeart failureDiuretic responseSerum chlorideThiazide diureticsWeight lossAssociated with smaller weight lossPatients admitted with acute heart failurePathophysiology of heart failureIn-hospital weight lossAssociated with higher weight lossObservational cohort studyDiuretic resistanceHF prognosisThiazideCohort studyDiureticsPatientsHyperchloraemiaOverall populationHypochloraemiaClinical sitesSerumSmall weight lossFailureClinical Validation of a Vaginal Cervical Cancer Screening Self-Collection Method for At-Home Use
Fitzpatrick M, Behrens C, Hibler K, Parsons C, Kaplan C, Orso R, Parker L, Memmel L, Collins A, McNicholas C, Crane L, Hwang Y, Sutton E, Coleman J, Kuroki L, Harshberger K, Williams S, Jennings A, Buccini F, Gillis L, Novetsky A, Hawkes D, Saville M, Depel T, Aviki E, Sheth S, Conageski C. Clinical Validation of a Vaginal Cervical Cancer Screening Self-Collection Method for At-Home Use. JAMA Network Open 2025, 8: e2511081. PMID: 40388167, PMCID: PMC12090030, DOI: 10.1001/jamanetworkopen.2025.11081.Peer-Reviewed Original ResearchConceptsCervical screeningPercentage agreementHigh-risk human papillomavirusScreening-eligible participantsSelf-collectionNonrandomized clinical trialDetection of high-risk human papillomavirusPositive percentage agreementMethod-comparison study designPrimary outcome measureHealth careUS womenSelf-collection methodDelayed screeningMain OutcomesAt-home settingClinical sensitivityOutcome measuresStudy designClinical sitesCervical dysplasiaStudy measuresDetection of high-grade cervical dysplasiaClinical trialsClinician-collected (CCParallel Detection of Multicontrast MRI and Deuterium Metabolic Imaging for Time-efficient Characterization of Neurologic Diseases.
Liu Y, De Feyter H, Corbin Z, Fulbright R, McIntyre S, Nixon T, de Graaf R. Parallel Detection of Multicontrast MRI and Deuterium Metabolic Imaging for Time-efficient Characterization of Neurologic Diseases. Radiology 2025, 315: e241597. PMID: 40197096, DOI: 10.1148/radiol.241597.Peer-Reviewed Original ResearchConceptsDeuterium metabolic imagingMRI protocolMetabolic imagingDecrease patient complianceUnique metabolic informationClinical MRI protocolsIn vivo human brain dataMRI examinationsMetabolism scansPatient compliancePatient populationNoninvasively in vivoDiverse patient populationsMRI-based methodMRIClinical sitesLong scan timesMetabolic informationScan qualityHuman brain dataNeurological diseasesImage contrastScan durationClinical MRIMulticontrast MRIForging a learning health system for early psychosis: Insights from the academic community EPINET
Vohs J, Cahill J, Taylor S, Heckers S, Weiss A, Chaudhry S, Silverstein S, Tso I, Breitborde N, Vinson A, Lapidos A, Visco A, Satchivi A, Gaunnac M, Breier A, Srihari V. Forging a learning health system for early psychosis: Insights from the academic community EPINET. Schizophrenia Research 2025, 278: 109-118. PMID: 40147210, PMCID: PMC12011207, DOI: 10.1016/j.schres.2025.03.020.Peer-Reviewed Original ResearchConceptsLearning healthcare systemEarly Psychosis Intervention NetworkQuality improvementClinical workflowLearning health systemProvision of intervention servicesQuality improvement effortsCulture of continuous learningIntervention NetworkHealth systemDisease trajectoryInterventional careHealthcare systemPractice-based researchImprovement effortsEvidence-basedClinical sitesIntervention servicesSocietal costsSteering CommitteeFirst-episode psychosisImplementation lessonsEarly psychosisEngaging stakeholdersSix-month intervalsExploration of the multi-level barriers to scaling up methadone for HIV prevention among people who inject drugs in Kazakhstan
Liberman A, Rozental Y, Ivasiy R, Kussainova A, Primbetova S, Madden L, Terlikbayeva A, Altice F. Exploration of the multi-level barriers to scaling up methadone for HIV prevention among people who inject drugs in Kazakhstan. Journal Of Substance Use And Addiction Treatment 2025, 172: 209640. PMID: 39986387, PMCID: PMC12009200, DOI: 10.1016/j.josat.2025.209640.Peer-Reviewed Original ResearchNominal group techniqueHIV preventionCommunity health workersMulti-level barriersIn-depth interviewsHealth workersPWID clientsSocioecological modelCommunity stakeholdersOpioid use disorderFocus groupsHIV epidemicClinical directorsClinical sitesEducating clientsOpioid agonist therapyImprove implementationGroup techniqueResearch teamCHWsPolicy levelUse disorderCliniciansAlternative medicationsEligibility
2024
NEAT: Nurse Effort Assessment Tool—Human Factors Considerations in Designing for Appropriate Staffing
Good S, Boyce M, Evans L, Sevilla M. NEAT: Nurse Effort Assessment Tool—Human Factors Considerations in Designing for Appropriate Staffing. Proceedings Of The Human Factors And Ergonomics Society Annual Meeting 2024, 68: 1680-1684. DOI: 10.1177/10711813241261347.Peer-Reviewed Original ResearchElectronic health recordsPatient-level informationHealth recordsAppropriate staffingIncreased acuityPatient assessmentBehavior patientsClinical sitesAssessment toolStatistically significant resultsPatient recordsNursesSignificant resultsSubjective ratingsPatientsStaffingAlgorithmFactors considerationsRecordsScoresAutomated AlgorithmAssessing readiness to use electronic health record data for outcome ascertainment in clinical trials – A case study
Esserman D, Greene E, Latham N, Kane M, Lu C, Peduzzi P, Gill T, Ganz D. Assessing readiness to use electronic health record data for outcome ascertainment in clinical trials – A case study. Contemporary Clinical Trials 2024, 142: 107572. PMID: 38740298, PMCID: PMC11654751, DOI: 10.1016/j.cct.2024.107572.Peer-Reviewed Original ResearchElectronic health record dataElectronic health recordsOutcome ascertainmentDevelop Confidence in EldersElectronic health record platformsClinical sitesPrimary care practicesHealth record dataMulti-site trialMulti-site clinical trialCare practicesHealth recordsAssess readinessAcute clinical outcomesHealthcare systemRecord dataClinical trialsReduce injuriesData qualityData comprehensionChecklistStudy dataClinical trial sitesVariable data qualityAscertainmentResting state electroencephalographic brain activity in neonates can predict age and is indicative of neurodevelopmental outcome
Ansari A, Pillay K, Arasteh E, Dereymaeker A, Mellado G, Jansen K, Winkler A, Naulaers G, Bhatt A, Van Huffel S, Hartley C, De Vos M, Slater R, Baxter L. Resting state electroencephalographic brain activity in neonates can predict age and is indicative of neurodevelopmental outcome. Clinical Neurophysiology 2024, 163: 226-235. PMID: 38797002, PMCID: PMC11250083, DOI: 10.1016/j.clinph.2024.05.002.Peer-Reviewed Original ResearchNeurodevelopmental outcomesResting state EEG dataBayley Scales of InfantAbnormal outcome groupsClinical sitesResting-state EEG activityPostmenstrual agePreterm neonatesOutcome groupNeonatesEEG activityBrain age gapElectroencephalographic brain activityBrain agingWeeksEEG dataGap magnitudeOutcomesBrainAgeIndependent datasetsPretermBSIDBrain activityInfantsAssociation between mindful and practical eating skills and eating behaviors among racially diverse pregnant women in four selected clinical sites in the United States
Carandang R, Epel E, Radin R, Lewis J, Ickovics J, Cunningham S. Association between mindful and practical eating skills and eating behaviors among racially diverse pregnant women in four selected clinical sites in the United States. Nutrition And Health 2024, 31: 757-766. PMID: 38584400, DOI: 10.1177/02601060241246353.Peer-Reviewed Original ResearchEating skillsEating behaviorsEmotional eatingNutritional intakePregnant womenQuality of nutritional intakeRacially diverse pregnant womenClinical sitesDiverse pregnant womenPregnant woman's abilityMethods:</b> ParticipantsHunger cuesHealthy eatingResidual change scoresChange scoresMyPlateFood diariesPredicted emotional eatingMindful eatingLogistic regressionWomen's abilityRegular useThird trimesterEatingPregnancyGroup prenatal care successes, challenges, and frameworks for scaling up: a case study in adopting health care innovations
Masters C, Carandang R, Lewis J, Hagaman A, Metrick R, Ickovics J, Cunningham S. Group prenatal care successes, challenges, and frameworks for scaling up: a case study in adopting health care innovations. Implementation Science Communications 2024, 5: 20. PMID: 38439113, PMCID: PMC10913654, DOI: 10.1186/s43058-024-00556-1.Peer-Reviewed Original ResearchGroup prenatal carePrenatal careGroup prenatal care sessionsLeadership buy-inQuality of careHealth care innovationsNon-adoptersFocus group discussionsOrganization-wide goalsCare implementationCare innovationsIntervention designCare sessionsCase study approachImprovement initiativesTransformative changeAdministrative dataHealthcare innovationOrganizational goalsCareOrganization leadershipClinical sitesGroup careTrial registrationTheBuy-inAvailability of substance use screening and treatment within HIV clinical sites across seven geographic regions within the IeDEA consortium
Lancaster K, Stockton M, Remch M, Wester C, Nash D, Brazier E, Adedimeji A, Finlayson R, Freeman A, Hogan B, Kasozi C, Kwobah E, Kulzer J, Merati T, Tine J, Poda A, Succi R, Twizere C, Tlali M, von Groote P, Edelman E, Parcesepe A, Consortium I. Availability of substance use screening and treatment within HIV clinical sites across seven geographic regions within the IeDEA consortium. International Journal Of Drug Policy 2024, 124: 104309. PMID: 38228025, PMCID: PMC10939808, DOI: 10.1016/j.drugpo.2023.104309.Peer-Reviewed Original ResearchAlcohol use disorder screeningHIV clinical sitesHIV care settingsProportion of clinicsSubstance use disordersAlcohol use disorderBrief interventionHIV careCare settingsClinical sitesSubstance use disorder screeningTreatment availabilityNegative impact of substance useHIV clinical settingsAvailability of screeningReferral to treatmentInternational epidemiology DatabasesHigh-income countiesImpact of substance useLower-middle-income countriesTreat alcohol use disorderUpper-middle income countriesLow-income countriesEpidemiological databasePrevalence estimates
2023
CAN‐THUMBS UP: Recruitment in the Virtual Era
Nygaard H, Slack P, Feldman H, Chertkow H, Belleville S, Montero‐Odasso M, Anderson N, Bennett D, Borrie M, Chan S, Jarrett P, Lee A, Lupo J, Matthews G, McGibbon C, Revta C, Robillard J, Shadyab A, Shajan S. CAN‐THUMBS UP: Recruitment in the Virtual Era. Alzheimer's & Dementia 2023, 19 DOI: 10.1002/alz.075155.Peer-Reviewed Original ResearchMajority of participantsUp StudyModifiable lifestyle risk factorsLifestyle risk factorsHealth support programInteractive educational interventionComprehensive recruitment strategyConclusions RecruitmentDementia literacyClinical trialsRisk factorsSpecialty clinicClinical cohortBasic demographic informationFuture recruitment effortsClinical sitesMedical clinicsSpecific target populationCohortTraditional recruitment methodsDiverse Canadian populationEducational interventionTarget cohortCanadian populationDemographic informationCharacterizing Outpatient Classical Hematology Referrals at an Academic Healthcare System
Chang E, Kress A, Ackermann F, Fradkin M, Halene S, Herbert E, Shomsky L, Sudhakar L, Lee A, Bona R. Characterizing Outpatient Classical Hematology Referrals at an Academic Healthcare System. Blood 2023, 142: 7196. DOI: 10.1182/blood-2023-186065.Peer-Reviewed Original ResearchIron deficiency anemiaAdvanced practice providersManual chart reviewChart reviewDeficiency anemiaHematology referralCommon diagnosisNew patientsAnemia groupDiagnosis levelClinical sitesIron deficiency groupAcademic healthcare systemHealthcare systemICD-10 codesNew patient encountersICD diagnosis codesSubstantial patient populationLevel 1 casesLevel 1Available cliniciansThrombosis groupAdditional patientsLevel 3New referralsUnfilled in emergency medicine: An analysis of the 2022 and 2023 Match by program accreditation, ownership, and geography
Gettel C, Bennett C, Rothenberg C, Smith J, Goldflam K, Sun W, Venkatesh A. Unfilled in emergency medicine: An analysis of the 2022 and 2023 Match by program accreditation, ownership, and geography. AEM Education And Training 2023, 7: e10902. PMID: 37600854, PMCID: PMC10436034, DOI: 10.1002/aet2.10902.Peer-Reviewed Original ResearchEM residency programsClinical sitesResidency programsGreater riskCross-sectional observational studyPrimary outcomeObservational studyProfit ownershipResidency program characteristicsMedicaid ServicesEmergency medicineCore-based statistical areasGraduate Medical EducationHigher numberRiskAccreditation CouncilDurationMatch cycleProgram characteristicsYearsStatusAvailable dataResidency positionsPerceived Stress and Depressive Symptoms Are Associated With Emotional Eating but Not Nutritional Intake During Pregnancy: A Prospective Cohort Study
Carandang R, Epel E, Radin R, Lewis J, Ickovics J, Cunningham S. Perceived Stress and Depressive Symptoms Are Associated With Emotional Eating but Not Nutritional Intake During Pregnancy: A Prospective Cohort Study. Journal Of Midwifery & Women's Health 2023, 69: 64-70. PMID: 37358371, DOI: 10.1111/jmwh.13537.Peer-Reviewed Original ResearchThird trimesterNutritional intakeDepressive symptomsPregnant womenPsychological distressEmotional eatingProspective cohort studySocial supportAssociation of changesDiverse pregnant womenHigher depressive symptomsLogistic regression modelsCohort studyProspective studySecond trimesterPregnancyTrimesterClinical sitesSymptomsIntakeMajor life eventsMental healthChange scoresWomenGreater likelihoodKetamine versus ECT for Nonpsychotic Treatment-Resistant Major Depression
Anand A, Mathew S, Sanacora G, Murrough J, Goes F, Altinay M, Aloysi A, Asghar-Ali A, Barnett B, Chang L, Collins K, Costi S, Iqbal S, Jha M, Krishnan K, Malone D, Nikayin S, Nissen S, Ostroff R, Reti I, Wilkinson S, Wolski K, Hu B. Ketamine versus ECT for Nonpsychotic Treatment-Resistant Major Depression. New England Journal Of Medicine 2023, 388: 2315-2325. PMID: 37224232, DOI: 10.1056/nejmoa2302399.Peer-Reviewed Original ResearchConceptsTreatment-resistant major depressionPatient-reported qualityElectroconvulsive therapyMajor depressionECT groupKetamine groupTreatment phaseMusculoskeletal adverse effectsSubanesthetic intravenous ketamineWeeks of treatmentInitial treatment phaseIntravenous ketamineSecondary outcomesPrimary outcomeNoninferiority marginTrial groupECT clinicsNoninferiority trialPatientsComparative effectivenessKetamineClinical sitesAdverse effectsDepressionThree timesImage guided dilation of sinus ostium in revision sinus surgery
Han J, Palmer J, Adappa N, Nachlas N, Chandra R, Jacobs J, Manes R, McKenzie K. Image guided dilation of sinus ostium in revision sinus surgery. American Journal Of Otolaryngology 2023, 44: 103803. PMID: 36889144, DOI: 10.1016/j.amjoto.2023.103803.Peer-Reviewed Original ResearchConceptsRevision sinus surgeryAdverse eventsSinus ostiumSinus surgeryUS clinical sitesOperative adverse eventsBalloon sinus dilationSphenoid sinus ostiumCardiac complicationsMulticenter studyMaxillary sinusSinus dilationSafety outcomesSinusClinical sitesEndoscopic photosPerformance endpointOstiumSurgeryDilation systemSurgeon's abilitySubjectsDirect causeDilationOutcomes
2022
Real-world abdominal aorta aneurysm screening patterns among patients with new or worsening of symptomatic peripheral artery disease
Lee M, Pichert M, Tran A, Farooq A, Heyligers J, de Vries J, Spertus J, Guzman R, Thomas M, Mena-Hurtado C, Smolderen K. Real-world abdominal aorta aneurysm screening patterns among patients with new or worsening of symptomatic peripheral artery disease. International Journal Of Cardiology 2022, 375: 94-97. PMID: 36577485, PMCID: PMC10371801, DOI: 10.1016/j.ijcard.2022.12.042.Peer-Reviewed Original ResearchConceptsPeripheral artery diseaseAbdominal aortic aneurysmScreening ratesArtery diseaseSpecialty centersAdjusted median odds ratioSymptomatic peripheral artery diseaseInternational prospective registryHigh-risk populationMedian odds ratioAbdominal aorta aneurysmAAA positivityMulticenter registryPAD symptomsProspective registryGuideline implementationAortic aneurysmAAA screeningAorta aneurysmOdds ratioPAD managementDisease RegistryPatientsMedian oddsClinical sitesGut microbiome dysbiosis in antibiotic-treated COVID-19 patients is associated with microbial translocation and bacteremia
Bernard-Raichon L, Venzon M, Klein J, Axelrad J, Zhang C, Sullivan A, Hussey G, Casanovas-Massana A, Noval M, Valero-Jimenez A, Gago J, Putzel G, Pironti A, Wilder E, Thorpe L, Littman D, Dittmann M, Stapleford K, Shopsin B, Torres V, Ko A, Iwasaki A, Cadwell K, Schluter J. Gut microbiome dysbiosis in antibiotic-treated COVID-19 patients is associated with microbial translocation and bacteremia. Nature Communications 2022, 13: 5926. PMID: 36319618, PMCID: PMC9626559, DOI: 10.1038/s41467-022-33395-6.Peer-Reviewed Original ResearchConceptsGut microbiome dysbiosisCOVID-19 patientsMicrobiome dysbiosisSecondary infectionSARS-CoV-2 infection inducesLife-threatening secondary infectionsTranslocation of bacteriaBlood culture resultsCOVID-19 severityAntimicrobial-resistant speciesCOVID-19Different clinical sitesMicrobial translocationBloodstream infectionsInfection inducesBarrier permeabilitySystemic circulationDysbiosisGoblet cellsPaneth cellsClinical sitesCulture resultsPatient healthGut microbiomePatients
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