2025
Proposed Policy Changes to Cancer Care and Oncologic Drug Reimbursement: Exploring the Rationale and Anticipating the Consequences.
Huey R, Pritchett J, Vokinger K, Swenson W, Haddad T, Adelson K. Proposed Policy Changes to Cancer Care and Oncologic Drug Reimbursement: Exploring the Rationale and Anticipating the Consequences. American Society Of Clinical Oncology Educational Book 2025, 45: e473822. PMID: 40526882, DOI: 10.1200/edbk-25-473822.Peer-Reviewed Original ResearchConceptsCancer care deliveryCancer care costsSite of careRemote patient monitoringCare deliveryCancer careCost-containment strategiesUnited StatesTelehealth servicesCare costsVulnerable populationsPayment barriersPayment parityFacility feesCareStandard of careIncremental costHospitalHealthReimbursementPolicy changesPatient monitoringCancer treatmentUnintended consequencesComparator countriesImproving Access to Perinatal Mental Health Care in Miami: An Initial Study [ID 1413]
Desai R, Kumar M, Dalwalla M, Torres C, Paidas M, Gallucci F. Improving Access to Perinatal Mental Health Care in Miami: An Initial Study [ID 1413]. Obstetrics And Gynecology 2025, 145: 9s-9s. DOI: 10.1097/aog.0000000000005916.028.Peer-Reviewed Original ResearchPerinatal mental health careMental health careMental health providersPerinatal psychiatristsHealth careMental health professionalsReferral processHealth providersHealth professionalsHigher health care costsEffect sizePregnancy-related deathsLength of timeMental health conditionsMental health needsPoor birth outcomesHealth care costsEvaluate effect sizesHealth needsMaternal morbidityMaternity careBirth outcomesInpatient servicesAverage length of timeCare costsMedicaid Costs and Outcomes for Patients Treated in an Outpatient Telepsychiatry Clinic
Havlik J, Ghomi R, An N, Budhiraja P, Arzubi E. Medicaid Costs and Outcomes for Patients Treated in an Outpatient Telepsychiatry Clinic. JAMA Network Open 2025, 8: e258558. PMID: 40323598, PMCID: PMC12053525, DOI: 10.1001/jamanetworkopen.2025.8558.Peer-Reviewed Original ResearchConceptsTelepsychiatry clinicRate of admissionCross-sectional studyMedicaid costsEmergency departmentClinical servicesMedicaid patientsHospitalization ratesTelepsychiatry patientsEvidence of cost savingsReduce hospital admissionsInpatient hospitalization ratesClinic patientsAnnual hospitalization rateOutcomes associated with useTelepsychiatry carePropensity-matched controlsTimely carePsychiatric careMain OutcomesCare costsPMPM costsHospital readmissionInpatient hospitalizationTelepsychiatryEconomic Burden of Patients With Chronic Idiopathic Constipation in the USA Before and After Prucalopride Initiation
Feuerstadt P, Lu M, Terasawa E, Terreri B, Du S, Pi S, Westermeyer B, Ayyagari R, Lembo A, Moshiree B, Boules M, Cash B. Economic Burden of Patients With Chronic Idiopathic Constipation in the USA Before and After Prucalopride Initiation. Gastro Hep Advances 2025, 4: 100664. PMID: 40491438, PMCID: PMC12148438, DOI: 10.1016/j.gastha.2025.100664.Peer-Reviewed Original ResearchChronic idiopathic constipationHealth care resource utilizationHealth care costsCare costsIdiopathic constipationEvaluate health care resource utilizationMedication useStudy periodMedical health care costsMedical costsProportion of patientsIBM MarketScan Commercial ClaimsEconomic burdenEconomic burden of patientsMarketScan Commercial ClaimsIncreased pharmacy costsAssessed 6 monthsBurden of patientsTreatment initiationPrucaloprideAll-CauseOutpatient visitsPrescription fillsPatientsDiagnosis codesCosts and cost-effectiveness of integrated screening for non-communicable diseases in TB contacts
Hamada Y, Mukora R, Pelusa R, Ntshiqa T, Shedrawy J, Velen K, Abubakar I, Charalambous S, Walker S, Rangaka M. Costs and cost-effectiveness of integrated screening for non-communicable diseases in TB contacts. IJTLD OPEN 2025, 2: 160-165. PMID: 40092516, PMCID: PMC11906026, DOI: 10.5588/ijtldopen.24.0625.Peer-Reviewed Original ResearchNon-communicable diseasesDisability-adjusted life yearsNon-communicable disease screeningNon-communicable disease casesIncremental cost-effectiveness ratioIncremental costCardiovascular diseaseCross-sectional studyHigh riskCost-effectiveHousehold contact investigationCVD riskCare costsCost-effectiveness ratioHealthcare perspectiveAssessed patientsLife yearsProvider costsIntegrated screeningImprove cost-effectivenessPrioritising individualsContact investigationTB contactDrug costsRiskReturn on Investment of Enhanced Behavioral Health Services
Hawrilenko M, Smolka C, Ward E, Ambwani G, Brown M, Mohandas A, Paulus M, Krystal J, Chekroud A. Return on Investment of Enhanced Behavioral Health Services. JAMA Network Open 2025, 8: e2457834. PMID: 39908020, PMCID: PMC11800021, DOI: 10.1001/jamanetworkopen.2024.57834.Peer-Reviewed Original ResearchConceptsBehavioral health careBehavioral health servicesBehavioral health diagnosesHealth care costsHealth diagnosisBehavioral health benefitsProgram groupHealth servicesHealth careCare costsPhysical health care costsCohort studyMedical claimsMedical spendingBehavioral health appointmentsBehavioral health programsBehavioral health conditionsMental health diagnosesBehavioral health costsHealth benefitsDifference-in-differences analysisMedication risk scoreIn-person psychotherapyMedical cost savingsMedical managementMechanical Circulatory Support in Patients Without Cardiogenic Shock Undergoing Percutaneous Coronary Intervention
Miller P, Gordon A, Liu Y, Ahmad T, Bromfield S, Girotra S, Davila C, Crawford G, Whitney J, Desai N. Mechanical Circulatory Support in Patients Without Cardiogenic Shock Undergoing Percutaneous Coronary Intervention. Journal Of The American Heart Association 2025, 14: e037424. PMID: 39791394, PMCID: PMC12054512, DOI: 10.1161/jaha.124.037424.Peer-Reviewed Original ResearchConceptsMicroaxial left ventricular assist deviceIntra-aortic balloon pump usePercutaneous coronary interventionIntra-aortic balloon pumpBalloon pump useCardiogenic shockLeft ventricular assist deviceTotal health care costsIndex admissionBalloon pumpIncident dialysisHealth care costsCoronary interventionAssociated with lower mortalityPump useLVAD useHigh-risk percutaneous coronary interventionAssociated with higher costsInverse probability treatmentCare costsMechanical circulatory supportInsured populationSecondary outcomesPrimary outcomeRetrospective study
2024
GEAR 2.0 ‐ Detection of Dementia and Cognitive Impairment
Hwang U. GEAR 2.0 ‐ Detection of Dementia and Cognitive Impairment. Alzheimer's & Dementia 2024, 20: e091835. PMCID: PMC11711980, DOI: 10.1002/alz.091835.Peer-Reviewed Original ResearchDetection of dementiaEmergency departmentOlder adultsED-based careImprove care coordinationUnder-recognitionAcute medical careIncreased health care costsRate of cognitive declineLower patient satisfactionCognitive declineHealth care costsAccelerated cognitive declineCare coordinationCare partnersEmergency carePatient safetyAvoidable visitsImplement interventionsInpatient servicesStaff's abilityCare costsMedical carePatient satisfactionCareCurrent out of pocket care costs among HIV and hypertension co-morbid patients in urban and peri-urban Uganda
Cameron D, Morrell L, Kagoya F, Kiggundu J, Hutchinson B, Twine R, Schwartz J, Muddu M, Mutungi G, Kayima J, Katahoire A, Longenecker C, Nugent R, Loya D, Semitala F. Current out of pocket care costs among HIV and hypertension co-morbid patients in urban and peri-urban Uganda. PLOS Global Public Health 2024, 4: e0003423. PMID: 39321165, PMCID: PMC11423963, DOI: 10.1371/journal.pgph.0003423.Peer-Reviewed Original ResearchCost of careHousehold incomeCo-morbid patientsCare costsMedian monthly household incomeHIV careCOVID-19 lockdownCascade of HIV careHIV care costsSocio-demographic characteristicsQuarter of patientsDistricts of UgandaIntegration of careMedian monthly costBorrow moneyOut-of-pocket costsDisease co-morbiditiesMonthly household incomePeri-urban UgandaService integrationUgandaHTN careCo-morbiditiesEast AfricaHypertension careCost‐effectiveness of a primary care‐based Healthy Weight Clinic compared with usual care
Sharifi M, Fiechtner L, Barrett J, O'Connor G, Perkins M, Reiner J, Luo M, Taveras E, Gortmaker S. Cost‐effectiveness of a primary care‐based Healthy Weight Clinic compared with usual care. Obesity 2024, 32: 1734-1744. PMID: 39192764, PMCID: PMC11361715, DOI: 10.1002/oby.24111.Peer-Reviewed Original ResearchConceptsHealthy weight clinicHealth care sectorObesity prevalenceIntervention costsCare sectorReducing obesity disparitiesNational implementationHealth care costsObesity disparitiesUsual careBMI changeCare costsFQHCsCost-effectiveSocietal perspectiveWhite populationHealthHealthyObesityQALYEstimated costInterventionClinicChildrenGreater reductionsACO leakage among gynecologic cancer patients: Incidence, predictors, and impact on annual Medicare expenditure
Osazuwa-Peters O, Greiner M, Kaufman B, Zambrano Guevara L, Dinan M, Havrilesky L, Moss H. ACO leakage among gynecologic cancer patients: Incidence, predictors, and impact on annual Medicare expenditure. Gynecologic Oncology 2024, 187: 184-191. PMID: 38788516, DOI: 10.1016/j.ygyno.2024.05.020.Peer-Reviewed Original ResearchAccountable care organizationsGynecologic cancer patientsACO sizeYear of cancer diagnosisReceipt of healthcareLog-binomial regression modelsCancer patientsNon-ACO providersPatients seeking careAdjusted risk ratiosHealth care costsAnnual Medicare expendituresMedian household incomeAssociated with useCare organizationsOutpatient careMedicare expendituresCare costsHealthcare costsMedicare spendingCancer diagnosisOutpatient settingHousehold incomeRisk ratioMultivariable adjusted risk ratiosComa Prognostication After Acute Brain Injury
Fischer D, Edlow B. Coma Prognostication After Acute Brain Injury. JAMA Neurology 2024, 81: 405-415. PMID: 38436946, DOI: 10.1001/jamaneurol.2023.5634.Peer-Reviewed Original ResearchMagnetic resonance imagingPrognostic markerAcute brain injuryLife-sustaining treatmentBrain injury etiologyPatient's current levelPrediction of neurological recoveryHealth care costsBrain injuryPatient valuesInjury etiologyCare costsPrognostic utilityComa prognosticationSerological markersClinical guidelinesComputed tomographyNeurological recoveryNeurological examinationDisorders of consciousnessNeurological assessmentNeurological functionPredictive valueResonance imagingNeuroprognosticationEvaluation of a collaborative model between managed care and affordable housing on acute care costs.
Tsai J, Rajan S, Truong C, Schick V, Ganduglia Cazaban C. Evaluation of a collaborative model between managed care and affordable housing on acute care costs. The American Journal Of Managed Care 2024, 30: 133-138. PMID: 38457821, DOI: 10.37765/ajmc.2024.89514.Peer-Reviewed Original ResearchConceptsEmergency department/urgent care visitsHealth care outcomesCollaborative modelAcute care costsHealth care coverageCommunity serviceCare outcomesHousing communitiesCare visitsCare coverageCollaborative service modelCare costsPrescription costsMedical claimsMedicaid MCOsProsperaService modelHousingResearch designMCOParticipantsCommunityEconomic valueServicesHealthplanUnderstanding and Preparing for Value-Based Care: A Primer for Behavioral Health Providers
Rothrock N, Bott N, Douglas S, McKune E, Owings-Fonner N, Ross D, Stephens K, Bard D, Bobbitt B, Childs A, Doucette A, Hepner K, Lanca M, Lysell K, Wright C. Understanding and Preparing for Value-Based Care: A Primer for Behavioral Health Providers. Professional Psychology Research And Practice 2024, 55: 68-78. DOI: 10.1037/pro0000537.Peer-Reviewed Original Research
2023
Real-World Comparison of Healthcare Costs of Venetoclax-Obinutuzumab Vs. Btki Use Among Elderly U.S. Medicare Beneficiaries with Chronic Lymphocytic Leukemia in the Front-Line (1L) Setting
Manzoor B, Huntington S, Jawaid D, Puckett J, Emechebe N, Ravelo A, Kamal-Bahl S, Doshi J. Real-World Comparison of Healthcare Costs of Venetoclax-Obinutuzumab Vs. Btki Use Among Elderly U.S. Medicare Beneficiaries with Chronic Lymphocytic Leukemia in the Front-Line (1L) Setting. Blood 2023, 142: 5085. DOI: 10.1182/blood-2023-177939.Peer-Reviewed Original ResearchChronic lymphocytic leukemiaPost-index periodU.S. Medicare beneficiariesBTK inhibitorsHealth care costsMedicare beneficiariesTreatment periodIndex dateMonth 13Months 0Prescription coverageLymphocytic leukemiaHealthcare costsCare costsMonths post-index periodDiagnosis of CLLMonthly health care costsMonthly costCause total costsFixed-duration treatmentPre-index periodPrior CLL treatmentTreatment-free remissionBCL-2 inhibitor venetoclaxFront-line settingEndoscopic Ultrasound in Cancer Staging
Aslanian H, Muniraj T, Nagar A, Parsons D. Endoscopic Ultrasound in Cancer Staging. Gastrointestinal Endoscopy Clinics Of North America 2023, 34: 37-49. PMID: 37973230, DOI: 10.1016/j.giec.2023.09.009.Peer-Reviewed Original ResearchDefining Priorities in Value-Based Cancer Care: Insights From the Alliance for Clinical Trials in Oncology National Cooperative Group Survey
Allen C, Snyder R, Horn D, Hudson M, Barber A, Smieliauskas F, Spears P, Edge S, Greenup R. Defining Priorities in Value-Based Cancer Care: Insights From the Alliance for Clinical Trials in Oncology National Cooperative Group Survey. JCO Oncology Practice 2023, 19: 932-938. PMID: 37651652, PMCID: PMC10615548, DOI: 10.1200/op.23.00159.Peer-Reviewed Original ResearchConceptsPatient-reported outcomesInclusion of PROsQuality of lifePatients' QOLClinical trialsHealth care systemHealth system performanceCancer CenterCancer-related health care costsCare systemTherapeutic assessmentAcademic cancer centerEvidence-based careCancer clinical trialsDirect patient careHealth care costsNational Cancer InstituteOncologic outcomesOverall survivalMedical oncologistsCancer careOncology practiceCancer InstituteNonphysician providersCare costsReceipt of Electroconvulsive Therapy in Outpatient Settings in a National Sample of Privately Insured Patients With Mood Disorders
Agbese E, Leslie D, Rosenheck R. Receipt of Electroconvulsive Therapy in Outpatient Settings in a National Sample of Privately Insured Patients With Mood Disorders. Journal Of Ect 2023, 40: 31-36. PMID: 37530796, DOI: 10.1097/yct.0000000000000950.Peer-Reviewed Original ResearchConceptsElectroconvulsive therapyReduce cost barriersMood disordersHealth care costsOutpatient settingPrivately insured patientsCare costsNational sample of privately insured patientsProportion of privately insured patientsReceipt of electroconvulsive therapyInpatient electroconvulsive therapyCost barriersOutpatient electroconvulsive therapyMarketScan Commercial DatabaseDepressive disorderCompared 4 groupsGroup differencesInpatient settingMoodNational sampleEffective treatmentPatientsDisordersOutpatientsHealthRoutine post-operative labs and healthcare system burden in acute appendicitis
Sznol J, Becher R, Maung A, Bhattacharya B, Davis K, Schuster K. Routine post-operative labs and healthcare system burden in acute appendicitis. The American Journal Of Surgery 2023, 226: 571-577. PMID: 37291012, DOI: 10.1016/j.amjsurg.2023.06.005.Peer-Reviewed Original ResearchConceptsHealthcare system burdenSystem burdenHealth care costsAppendicitis managementIncreased LOSUncomplicated AAAcute appendicitisRetrospective cohortClinical courseClinical variablesPatient populationMinimal comorbiditiesMultivariable modelingHealthcare costsCare costsPatientsLaboratory utilizationNational Health Expenditure AccountsLab utilizationLaboratory testingBurdenLaboratory testsAppendicitisComorbiditiesCohortInternet-Delivered, Therapist-Assisted Treatment for Anxiety and Depression in Patients with Cardiovascular Disease: Evidence-Base and Challenges
Pedersen S, Skovbakke S, Skov O, Carlbring P, Burg M, Habibović M, Ahm R. Internet-Delivered, Therapist-Assisted Treatment for Anxiety and Depression in Patients with Cardiovascular Disease: Evidence-Base and Challenges. Current Cardiology Reports 2023, 25: 443-453. PMID: 37119450, DOI: 10.1007/s11886-023-01867-w.Peer-Reviewed Original ResearchConceptsInternet-based psychological interventionsFace-to-face therapyTherapist-assisted treatmentInterventions targeting anxietyInternet-based therapyCardiovascular diseaseComorbid anxietyPsychological interventionsDevelopment of interventionsAssessment of fidelityHealth care costsAnxietyDepressionTreatment adherenceHealth literacyFace-to-faceHealth careCare costsPatient reportsEvidence-basedClinical outcomesReviewThis reviewHealthPatientsIntervention
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