2025
Association of Causative Pathogens With Acute Kidney Injury in Adult Patients With Community-Onset Sepsis
Pant P, Chihara S, Krishnamoorthy V, Treggiari M, Messina J, Privratsky J, Raghunathan K, Ohnuma T. Association of Causative Pathogens With Acute Kidney Injury in Adult Patients With Community-Onset Sepsis. Critical Care Explorations 2025, 7: e1219. PMID: 39937578, PMCID: PMC11826047, DOI: 10.1097/cce.0000000000001219.Peer-Reviewed Original ResearchConceptsAcute kidney injuryOdds of acute kidney injuryDevelopment of acute kidney injuryCommunity-onset sepsisAdult patientsKidney injuryAssociated with increased odds of AKICausative pathogenPINC AI Healthcare DatabaseAcute kidney injury riskMultilevel logistic regressionGlobal Outcomes serum creatinine criteriaAssociated with decreased oddsAssociated with increased oddsSerum creatinine criteriaStage 1 AKIStage 3 AKIStage 2 AKIRetrospective cohort studyCritically ill patientsDay of admissionE. coli infectionCommunity-onsetCreatinine criteriaMedian age
2024
POLYGENIC RISK SCORE FOR DIABETES PREDICTS POSTOPERATIVE ACUTE KIDNEY INJURY
Leis A, Mathis M, Smith J, Mukherjee B, Karvonen-Gutierrez C. POLYGENIC RISK SCORE FOR DIABETES PREDICTS POSTOPERATIVE ACUTE KIDNEY INJURY. Innovation In Aging 2024, 8: 132-133. PMCID: PMC11689292, DOI: 10.1093/geroni/igae098.0427.Peer-Reviewed Original ResearchPolygenic risk scoresAcute kidney injuryKidney Disease-Improving Global OutcomesOdds of acute kidney injuryPostoperative acute kidney injuryPredicting postoperative acute kidney injuryRisk scoreKidney injuryAcute kidney injury prevalenceLogistic regression modelsOlder adultsT2DM statusType 2 diabetesInformation biasPRS modelTransplant surgical proceduresAnalysis of outcomesGenetic cohortsDiabetes statusLowest decileIntraoperative factorsNon-cardiacNon-renalNon-urologicalSurgical proceduresSex, Acute Kidney Injury, and Age: A Prospective Cohort Study
Golestaneh L, Basalely A, Linkermann A, El-Achkar T, Kim R, Neugarten J. Sex, Acute Kidney Injury, and Age: A Prospective Cohort Study. American Journal Of Kidney Diseases 2024, 85: 329-338.e1. PMID: 39447957, DOI: 10.1053/j.ajkd.2024.10.003.Peer-Reviewed Original ResearchConceptsRisk of acute kidney injuryAcute kidney injuryFemale sex hormonesSex hormonesKidney injuryRelative risk of acute kidney injuryOdds of acute kidney injuryAnimal models of kidney diseaseRisk factorsAcute kidney injury incidenceHospital-acquired acute kidney injuryWomen of fertile ageModels of kidney diseaseAbstractText Label="PLAIN-LANGUAGE SUMMARYAge groupsEquation logistic regressionSeverity of illnessPostmenopausal womenKDIGO definitionAbstractText Label="RATIONALEObstetric diagnosisAge categoriesMale sexCounts of hospitalizationsMontefiore Health SystemP27. Renal transplant patients at increased odds off many perioperative adverse events following lumbar laminotomy/discectomy
Gouzoulis M, Seddio A, Zhu J, Day W, Jabbouri S, Rubio D, Grauer J. P27. Renal transplant patients at increased odds off many perioperative adverse events following lumbar laminotomy/discectomy. The Spine Journal 2024, 24: s76. DOI: 10.1016/j.spinee.2024.06.048.Peer-Reviewed Original ResearchSevere adverse eventsHistory of renal transplantationUrinary tract infectionRenal transplantationAcute kidney injuryAdverse eventsMinor adverse eventsElixhauser Comorbidity IndexIncreased oddsCurrent Procedural TerminologyTract infectionsLumbar discectomyKidney injuryED visitsIncreased odds of acute kidney injuryOdds of acute kidney injuryOdds ratioOdds of ED visitsKaplan-Meier survival curvesDays of follow-upRenal transplant groupRenal transplant patientsIncidence of reoperationRisk of reoperationOdds of sepsis
2023
Cardiometabolic disease and obesity patterns differentially predict acute kidney injury after total joint replacement: a retrospective analysis
Leis A, Mathis M, Kheterpal S, Zawistowski M, Mukherjee B, Pace N, O'Reilly-Shah V, Smith J, Karvonen-Gutierrez C. Cardiometabolic disease and obesity patterns differentially predict acute kidney injury after total joint replacement: a retrospective analysis. British Journal Of Anaesthesia 2023, 131: 37-46. PMID: 37188560, PMCID: PMC10308436, DOI: 10.1016/j.bja.2023.04.001.Peer-Reviewed Original ResearchConceptsOdds of acute kidney injuryAcute kidney injuryCardiometabolic diseasesNon-Hispanic blacksGroup of hospitalsKidney injuryCardiometabolic patternTotal joint arthroplasty complicationsObesity statusObesity patternsIncreased oddsDisease co-occurrenceIncreased odds of AKIRetrospective analysisRisk of postoperative acute kidney injuryLatent class analysisLatent classesPostoperative acute kidney injuryRisk of acute kidney injuryRisk factorsDifferential riskTotal joint replacementMetabolic syndromeObesityPostoperative AKI risk
2022
Abstract P037: Impact Of Protein Energy Malnutrition On Inpatient Outcomes Of Hypertensives Emergencies : Insight From The National Inpatient Sample
Khanal S, Kannayairam S, Karki S, Poudyal A, Park D. Abstract P037: Impact Of Protein Energy Malnutrition On Inpatient Outcomes Of Hypertensives Emergencies : Insight From The National Inpatient Sample. Hypertension 2022, 79 DOI: 10.1161/hyp.79.suppl_1.p037.Peer-Reviewed Original ResearchAcute kidney injuryProtein-energy malnutritionImpact of protein energy malnutritionLength of stayHypertensive emergenciesTotal hospital chargesIn-Hospital MortalityInpatient DatabaseAssociated with higher oddsDiagnosis of protein-energy malnutritionOdds of acute kidney injuryAssociated with adverse clinical outcomesEnergy malnutritionMultivariate logistic regressionAdverse clinical outcomesEarly risk stratificationMean length of stayNational Inpatient SampleIn-Hospital OutcomesNational inpatient databaseHigher oddsIncreasing burdenSecondary outcomesInpatient SampleLogistic regression
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