2025
Repolarisation abnormalities and outcomes among patients with cardiac arrest
Schenck C, Banna S, Kim N, Nguyen C, Gilmore E, Greer D, Beekman R, Miller P. Repolarisation abnormalities and outcomes among patients with cardiac arrest. European Heart Journal Acute Cardiovascular Care 2025, zuaf077. PMID: 40424593, DOI: 10.1093/ehjacc/zuaf077.Peer-Reviewed Original ResearchReturn of spontaneous circulationIn-Hospital MortalityAssociated with in-hospital mortalityQTc prolongationCardiac arrestInterval prolongationShockable rhythmNeurological outcomeClinical outcomesAssociated with increased in-hospital mortalityAssociated with adverse clinical outcomesTpTe intervalT-peak to T-endSusceptibility to ventricular arrhythmiasQTc interval prolongationIn-hospital cardiac arrestAdverse clinical outcomesT-end (TpTeOut-of-hospitalT-endSpontaneous circulationVentricular arrhythmiasVentricular repolarizationQTcRepolarisation abnormalitiesPerioperative Anemia Management in Patients Undergoing Gynaecologic Procedures: A 12-Year Multisite Study
Gabarin N, Liu Y, Coll-Black M, Luketic L, Pai M, St John M, Shirinzadeh M, Sirotich E, Arnold D, Zeller M. Perioperative Anemia Management in Patients Undergoing Gynaecologic Procedures: A 12-Year Multisite Study. Journal Of Obstetrics And Gynaecology Canada 2025, 47: 102923. PMID: 40379250, DOI: 10.1016/j.jogc.2025.102923.Peer-Reviewed Original ResearchRed blood cell transfusionIntensive care unit admissionHospital length of stayRed blood cellsPreoperative anemiaLength of stayUnit admissionGynaecological surgeryGynaecological proceduresHospital lengthPerioperative periodPerioperative red blood cellAssociated with adverse clinical outcomesPatient blood management programDiagnosis of malignancyPerioperative RBC transfusionAdverse clinical outcomesRetrospective cohort studyBlood management programIn-Hospital MortalityPerioperative anaemia managementIron therapySurgery cohortIV ironRBC transfusion
2024
Association between Left Ventricular Geometry, Systolic Ejection Time, and Estimated Glomerular Filtration Rate in Ambulatory Patients with Preserved Left Ventricular Ejection Fraction
Goeddel L, Navarrete S, Waldron N, D’Amiano A, Faraday N, Lima J, Parikh C, Bandeen-Roche K, Hays A, Brown C. Association between Left Ventricular Geometry, Systolic Ejection Time, and Estimated Glomerular Filtration Rate in Ambulatory Patients with Preserved Left Ventricular Ejection Fraction. Cardiology 2024, 1-11. PMID: 39353411, PMCID: PMC11958786, DOI: 10.1159/000541725.Peer-Reviewed Original ResearchLeft ventricular ejection fractionTrans thoracic echocardiographyIncreased RWTRelative wall thicknessChronic kidney diseaseLeft ventricular ejection timeSubclinical systolic dysfunctionVentricular ejection fractionCardiac functionSystolic dysfunctionEjection fractionSystolic functionClinical outcomesPRESERVED LEFT VENTRICULAR EJECTION FRACTIONAmbulatory patientsAssociated with adverse clinical outcomesMeasures of LV geometryEjection timeAssociated with chronic kidney diseaseIncreased oddsMeasures of cardiac functionLV relative wall thicknessSubclinical cardiac dysfunctionIncreased odds of CKDOdds of chronic kidney diseaseImpact of Time to Initiation of Targeted Temperature Management Among Patients with Out-of-Hospital Cardiac Arrest Undergoing Percutaneous Coronary Intervention
Kovach C, Leonard J, Messenger J, Waldo S, Perman S. Impact of Time to Initiation of Targeted Temperature Management Among Patients with Out-of-Hospital Cardiac Arrest Undergoing Percutaneous Coronary Intervention. Therapeutic Hypothermia And Temperature Management 2024, 15: 74-81. PMID: 39311798, DOI: 10.1089/ther.2024.0030.Peer-Reviewed Original ResearchOdds of neurologically favorable survivalOut-of-hospital cardiac arrestST-elevation myocardial infarctionNeurologically favorable survivalPercutaneous coronary interventionInitiation of targeted temperature managementTemperature management initiationFavorable survivalOverall survivalHospital dischargeVentricular tachycardiaTemperature managementSurvivors of ventricular tachycardiaVentricular fibrillationCoronary interventionAssociated with adverse clinical outcomesDelayed coronary angiographyProportion of patientsAdverse clinical outcomesPropensity-weighted analysisAssociated with decreased oddsAssociated with delayWithdrawal of life-sustaining careLife-sustaining careCoronary angiographyPredictors of Disease Progression and Adverse Clinical Outcomes in Patients With Moderate Aortic Stenosis Using an Artificial Intelligence-Based Software Platform
Salem M, Gada H, Ramlawi B, Sotelo M, Nona P, Wagner L, Rogers C, Brigman L, Vora A. Predictors of Disease Progression and Adverse Clinical Outcomes in Patients With Moderate Aortic Stenosis Using an Artificial Intelligence-Based Software Platform. The American Journal Of Cardiology 2024, 223: 92-99. PMID: 38710350, DOI: 10.1016/j.amjcard.2024.04.051.Peer-Reviewed Original ResearchConceptsAdverse clinical outcomesRisk of adverse clinical outcomesModerate aortic stenosisClinical outcomesAortic stenosisDisease progressionSevere ASModerate ASAtrial fibrillationAmerican Heart Association/American College of Cardiology guidelinesLower left ventricular ejection fractionAssociated with adverse clinical outcomesPredictor of clinical outcomePredictors of disease progressionAmerican Heart Association/American CollegeFactors associated with outcomesVentricular ejection fractionEnd-stage renal diseaseHeart failure hospitalizationCox proportional hazards modelsProportional hazards modelSerial echoesAS severityEjection fractionCardiology guidelines
2022
Abstract P037: Impact Of Protein Energy Malnutrition On Inpatient Outcomes Of Hypertensives Emergencies : Insight From The National Inpatient Sample
Khanal S, Kannayairam S, Karki S, Poudyal A, Park D. Abstract P037: Impact Of Protein Energy Malnutrition On Inpatient Outcomes Of Hypertensives Emergencies : Insight From The National Inpatient Sample. Hypertension 2022, 79 DOI: 10.1161/hyp.79.suppl_1.p037.Peer-Reviewed Original ResearchAcute kidney injuryProtein-energy malnutritionImpact of protein energy malnutritionLength of stayHypertensive emergenciesTotal hospital chargesIn-Hospital MortalityInpatient DatabaseAssociated with higher oddsDiagnosis of protein-energy malnutritionOdds of acute kidney injuryAssociated with adverse clinical outcomesEnergy malnutritionMultivariate logistic regressionAdverse clinical outcomesEarly risk stratificationMean length of stayNational Inpatient SampleIn-Hospital OutcomesNational inpatient databaseHigher oddsIncreasing burdenSecondary outcomesInpatient SampleLogistic regression
2016
Blood Transfusion and the Risk of Acute Kidney Injury Among Patients With Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention
Karrowni W, Vora A, Dai D, Wojdyla D, Dakik H, Rao S. Blood Transfusion and the Risk of Acute Kidney Injury Among Patients With Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention. Circulation Cardiovascular Interventions 2016, 9 PMID: 27582110, DOI: 10.1161/circinterventions.115.003279.Peer-Reviewed Original ResearchMeSH KeywordsAcute Coronary SyndromeAcute Kidney InjuryAgedAnemiaBiomarkersBlood TransfusionChi-Square DistributionCreatinineFemaleHemoglobinsHemorrhageHumansLogistic ModelsMaleMiddle AgedOdds RatioPercutaneous Coronary InterventionPropensity ScoreRegistriesRetrospective StudiesRisk AssessmentRisk FactorsTime FactorsTransfusion ReactionTreatment OutcomeUnited StatesUp-RegulationConceptsAcute kidney injuryPercutaneous coronary interventionRisk of acute kidney injurySubgroup of patientsBlood transfusionAcute coronary syndromeKidney injuryCoronary syndromeAssociated with acute kidney injuryRates of acute kidney injuryAssociation of blood transfusionAssociated with adverse clinical outcomesCoronary interventionAdvanced stages of chronic kidney diseaseRestrictive blood transfusion strategyComplicating percutaneous coronary interventionStages of chronic kidney diseaseImprove PCI outcomesPreprocedural hemoglobin levelNo blood transfusionAdverse clinical outcomesRetrospective cohort studyBlood transfusion strategyChronic kidney diseasePrevalence of comorbidities
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