2023
Prepectoral versus Submuscular Implant-Based Breast Reconstruction: A Matched-Pair Comparison of Outcomes
Talwar A, Lanni M, Ryan I, Kodali P, Bernstein E, McAuliffe P, Broach R, Serletti J, Butler P, Fosnot J. Prepectoral versus Submuscular Implant-Based Breast Reconstruction: A Matched-Pair Comparison of Outcomes. Plastic & Reconstructive Surgery 2023, 153: 281e-290e. PMID: 37159266, DOI: 10.1097/prs.0000000000010618.Peer-Reviewed Original ResearchBreast reconstructionPrepectoral ImplantSecondary reconstructionSubmuscular reconstructionClinical outcomesSubmuscular implantsCapsular contracturePrepectoral reconstructionImplant-based breast reconstructionSurgical site infectionLarge academic medical centerSurgical site occurrenceAcademic medical centerMean followDeep infectionSite infectionNegative infectionsPostoperative differencesAntibiotic managementAnimation deformityMedical CenterCohort analysisExplantationInfectionPropensity scoreIs There an Implicit Racial Bias in the Case Order of Elective Total Joint Arthroplasty?
Kaidi A, Hammoor B, Tyler W, Geller J, Cooper H, Hickernell T. Is There an Implicit Racial Bias in the Case Order of Elective Total Joint Arthroplasty? Journal Of Racial And Ethnic Health Disparities 2023, 11: 1-6. PMID: 37095288, DOI: 10.1007/s40615-022-01492-3.Peer-Reviewed Original ResearchConceptsSurgical start timeTotal joint arthroplastyTotal hip arthroplastyMultivariable logistic regressionOdds ratioJoint arthroplastyArthroplasty fellowship-trained surgeonsElective total joint arthroplastyNon-Hispanic black patientsElective total hip arthroplastyPrimary total joint arthroplastySurgical case orderLarge academic medical centerFellowship-trained surgeonsAcademic medical centerSelf-reported raceTKA patientsBlack patientsAdverse outcomesSurgical typePatient raceTotal kneeInclusion criteriaHip arthroplastyMedical CenterMulticenter Transthyretin Cardiac Amyloidosis Study Demonstrates Differences In Phenotype And Outcomes By Race
Cavalier J, Bhattacharya P, Patolia H, Chandramouli S, Sen S, Karra R, Maurer M, Khouri M. Multicenter Transthyretin Cardiac Amyloidosis Study Demonstrates Differences In Phenotype And Outcomes By Race. Journal Of Cardiac Failure 2023, 29: 699-700. DOI: 10.1016/j.cardfail.2022.10.381.Peer-Reviewed Original ResearchATTR-CM patientsReduced ejection fractionEjection fractionBlack patientsATTR-CMHeart failureWhite patientsAdvanced stageFindings merit further researchHigher NT-proBNP levelsMid-range ejection fractionNT-proBNP levelsNYHA class INYHA class IIILow ejection fractionRetrospective multicenter analysisTransthyretin amyloid cardiomyopathyLarge academic medical centerCross-sectional studyAcademic medical centerDeceased patientsMulticenter analysisWorsened prognosisRace patientsVital statusTiming of Blood Draws Among Patients Hospitalized in a Large Academic Medical Center
Caraballo C, Mahajan S, Murugiah K, Mortazavi B, Lu Y, Khera R, Krumholz H. Timing of Blood Draws Among Patients Hospitalized in a Large Academic Medical Center. JAMA 2023, 329: 255-257. PMID: 36648476, PMCID: PMC9856620, DOI: 10.1001/jama.2022.21509.Peer-Reviewed Original ResearchConceptsBlood drawLarge academic medical centerAcademic medical centerHospitalized patientsMedical CenterSleep hoursPatientsAnalysis of Failure Rates for COVID-19 Entrance Screening at a US Academic Medical Center
Roberts S, Faruq R, Wilkinson A, Pashankar D, Russi M, Khokhar B, Martinello R. Analysis of Failure Rates for COVID-19 Entrance Screening at a US Academic Medical Center. JAMA Internal Medicine 2023, 183: 84-86. PMID: 36441528, PMCID: PMC9706395, DOI: 10.1001/jamainternmed.2022.5426.Peer-Reviewed Original Research
2022
Does Antenatal Progesterone Administration Modify the Risk of Neonatal Intraventricular Hemorrhage?
Leon-Martinez D, Bank TC, Lundsberg LS, Culhane J, Silasi M, Son M, Partridge C, Reddy UM, Hoffman MK, Merriam A. Does Antenatal Progesterone Administration Modify the Risk of Neonatal Intraventricular Hemorrhage? American Journal Of Perinatology 2022, 41: e46-e52. PMID: 35436803, DOI: 10.1055/a-1827-6712.Peer-Reviewed Original ResearchNeonatal intraventricular hemorrhageIntraventricular hemorrhageBrain injuryOdds ratioDiagnosis of IVHRisk of IVHImproved neurological outcomeNeonatal brain injuryLarge academic medical centerConfidence intervalsRoute of deliveryEffect of progesteroneTraumatic brain injuryAcademic medical centerHospitalization encountersNeurological outcomePreterm neonatesSingleton deliveriesMaternal administrationProgesterone administrationRetrospective studyAntepartum periodLow birthweightPotential confoundersDiagnosis codes
2021
Bundling cancer subtypes in value-based care: A pilot analysis of lymphoma episodes in the Oncology Care Model.
Yue A, Chaudhry B, Schleicher S, Huntington S, Lyss A, Connor N, Tran L, Adelson K. Bundling cancer subtypes in value-based care: A pilot analysis of lymphoma episodes in the Oncology Care Model. Journal Of Clinical Oncology 2021, 39: e18850-e18850. DOI: 10.1200/jco.2021.39.15_suppl.e18850.Peer-Reviewed Original ResearchCommunity oncology practicesAcademic medical centerOncology Care ModelEpisode costsWaldenstrom's macroglobulinemiaCare modelCancer subtypesLarge community oncology practiceProportion of subtypesLarge academic medical centerICD-10 diagnosisIntensity of careValue-based careCohort studyClinical featuresCommon subtypeFrequent subtypeOncology practiceLymphoma populationLymphoma subtypesMedical CenterHeterogeneous diseaseInappropriate shiftIndividual subtypesSubtypesEpidemiology, Infection Prevention, Testing Data, and Clinical Outcomes of COVID-19 on Five Inpatient Psychiatric Units in a large Academic Medical Center
Li L, Roberts SC, Kulp W, Wing A, Barnes T, Colandrea N, Klink B, Fortunati F, Martinello R. Epidemiology, Infection Prevention, Testing Data, and Clinical Outcomes of COVID-19 on Five Inpatient Psychiatric Units in a large Academic Medical Center. Psychiatry Research 2021, 298: 113776. PMID: 33571800, PMCID: PMC7987366, DOI: 10.1016/j.psychres.2021.113776.Peer-Reviewed Original ResearchConceptsInpatient psychiatric unitLarge academic medical centerAcademic medical centerPsychiatric unitMedical CenterCOVID-19Retrospective cohort analysisEmergency room visitsInpatient psychiatric facilityLow patientsClinical outcomesRoom visitsHospitalized individualsInfection preventionStudy populationCohort analysisPrevention strategiesAdmission statusTriage protocolDiverse patientsInfection rateMental illnessPsychiatric facilitiesDemographic dataPatientsStructured interdisciplinary bedside rounds improve interprofessional communication and workplace efficiency among residents and nurses on an inpatient internal medicine unit
Schwartz JI, Gonzalez-Colaso R, Gan G, Deng Y, Kaplan MH, Vakos PA, Kenyon K, Ashman A, Sofair AN, Huot SJ, Chaudhry SI. Structured interdisciplinary bedside rounds improve interprofessional communication and workplace efficiency among residents and nurses on an inpatient internal medicine unit. Journal Of Interprofessional Care 2021, 38: 427-434. PMID: 33433262, DOI: 10.1080/13561820.2020.1863932.Peer-Reviewed Original ResearchStructured interdisciplinary bedside roundsStructured interdisciplinary bedsideLarge academic medical centerInternal medicine unitsPatient-centered outcomesTeam-based interventionAcademic medical centerInterdisciplinary bedsideMedicine unitBedside nursesMedical CenterPatient experienceQuasi-experimental studyBedside roundsInterprofessional careNursesInterprofessional communicationCare managersHealthcare qualityBedsideWorkplace efficiencyOutcomesSignificant improvementResidentsWorkplace satisfactionLung-Protective Ventilation Over 6 Years at a Large Academic Medical Center: An Evaluation of Trends, Adherence, and Perceptions of Benefit
Gao CA, Howard FM, Siner JM, Candido TD, Ferrante LE. Lung-Protective Ventilation Over 6 Years at a Large Academic Medical Center: An Evaluation of Trends, Adherence, and Perceptions of Benefit. Critical Care Explorations 2021, 3: e0325. PMID: 33458691, PMCID: PMC7803935, DOI: 10.1097/cce.0000000000000325.Peer-Reviewed Original ResearchLung-protective ventilationIdeal body weightLarge academic medical centerSet tidal volumeTidal volumeAcademic medical centerAdult patientsMedical CenterBody weightVentilated adult patientsRetrospective observational analysisLow tidal volumeCross-sectional survey studyElectronic medical recordsElectronic medical record systemAdult ICUsMedical record systemSingle centerCardiothoracic ICUMedical recordsSecondary objectiveICUPatientsVentilationCurrent electronic medical record systems
2020
Implementation of an external female urinary catheter as an alternative to an indwelling urinary catheter
Warren C, Fosnacht J, Tremblay E. Implementation of an external female urinary catheter as an alternative to an indwelling urinary catheter. American Journal Of Infection Control 2020, 49: 764-768. PMID: 33157184, DOI: 10.1016/j.ajic.2020.10.023.Peer-Reviewed Original ResearchConceptsIndwelling urinary catheterUrinary catheter daysUrinary catheter utilizationUrinary catheterCatheter daysCatheter utilizationFemale patientsCatheter-associated urinary tract infection ratesCatheter-associated urinary tract infectionsUrinary tract infection rateUrinary tract infectionLarge academic medical centerIntensive care unitUrine output measurementsHospital-wide implementationYears of ageLevel of careAcademic medical centerTract infectionsCare unitRetrospective studyPatient daysMedical CenterCatheterInfection rate23-OR: EHR-Based Blood Glucose Alerts Improve Inpatient Glycemic Control at a Large Academic Medical Center
BAK L, FANDEL T, BOZZO J, DEWITT M, CHEN P, PANDO R, FERRO L, KAPLAN R, HENDRICKSON K, AMPORT S, SUSSMAN L, INZUCCHI S. 23-OR: EHR-Based Blood Glucose Alerts Improve Inpatient Glycemic Control at a Large Academic Medical Center. Diabetes 2020, 69 DOI: 10.2337/db20-23-or.Peer-Reviewed Original ResearchAcademic medical centerLarge academic medical centerMedical CenterBG controlEHR-based interventionsInsulin order setsNon-ICU wardsBlood glucose managementInpatient glycemic controlElectronic health recordsControl wardsGlycemic controlSignificant hyperglycemiaNovo Nordisk A/SGlucose managementScore 2Severe hyperIndividual wardsControl groupOrder setsWardsHealth recordsLexicon PharmaceuticalsBG managementHypoglycemiaPandemic Recovery Using a COVID-Minimal Cancer Surgery Pathway
Boffa DJ, Judson BL, Billingsley KG, Galetta D, Fontanez P, Odermatt C, Lindner K, Mitchell MR, Henderson CM, Carafeno T, Pinto J, Wagner J, Ancuta M, Beley P, Turner AL, Banack T, Laurans MS, Johnson DC, Yoo P, Morton JM, Zurich H, Davis K, Ahuja N. Pandemic Recovery Using a COVID-Minimal Cancer Surgery Pathway. The Annals Of Thoracic Surgery 2020, 110: 718-724. PMID: 32417195, PMCID: PMC7227551, DOI: 10.1016/j.athoracsur.2020.05.003.Peer-Reviewed Original ResearchConceptsSurgery pathwayHospital-acquired COVID-19 infectionLarge academic medical centerCOVID-19 patientsCoronavirus disease 2019 (COVID-19) pandemicCOVID-19 infectionPatient care pathwayAcademic medical centerDisease 2019 pandemicHealth care deliveryOnly surgerySurgery populationElective surgeryPatient survivalRisk of exposureProtection of patientsCare pathwayNosocomial infectionsMedical CenterCare deliverySurgical activityHospitalPatientsSurgeryMost hospitalsAssociation of Oxytocin Rest During Labor Induction of Nulliparous Women With Mode of Delivery.
McAdow M, Xu X, Lipkind H, Reddy UM, Illuzzi JL. Association of Oxytocin Rest During Labor Induction of Nulliparous Women With Mode of Delivery. Obstetrics And Gynecology 2020, 135: 569-575. PMID: 32028487, DOI: 10.1097/aog.0000000000003709.Peer-Reviewed Original ResearchConceptsMode of deliveryInduction of laborNeonatal morbidityCesarean deliveryNulliparous womenLatent laborOxytocin infusionLatent phaseMultivariable logistic regression analysisContinuous oxytocin infusionRetrospective cohort analysisLarge academic medical centerBody mass indexLogistic regression analysisAcademic medical centerContinuous oxytocinSingleton gestationsLabor inductionGestational ageMass indexPotential confoundersMaternal ageOdds ratioCohort analysisMedical Center
2019
Proapoptotic protein BIM as a novel prognostic marker in mantle cell lymphoma
Wang JD, Katz SG, Morgan EA, Yang DT, Pan X, Xu ML. Proapoptotic protein BIM as a novel prognostic marker in mantle cell lymphoma. Human Pathology 2019, 93: 54-64. PMID: 31425695, PMCID: PMC7038910, DOI: 10.1016/j.humpath.2019.08.008.Peer-Reviewed Original ResearchConceptsMantle cell lymphomaCell lymphomaAnn Arbor stage IIINovel independent prognostic factorAggressive B-cell lymphomasHigh Bim expressionAverage patient ageBim expressionIndependent prognostic factorLarge academic medical centerKi-67 indexNovel prognostic markerB-cell lymphomaAcademic medical centerCyclin D1 overexpressionHuman mantle cell lymphomaMCL cohortMIPI scoreProgressive diseaseComplete responseOverall survivalPatient agePrognostic factorsTumor cell survivalFemale ratioEtoposide phosphate for pediatric orthopedic malignancies after intravenous etoposide hypersensitivity
Brooks JP, Azmy V, Thompson A, Luon D, Prozora SD, Price C, Hsu FI. Etoposide phosphate for pediatric orthopedic malignancies after intravenous etoposide hypersensitivity. Journal Of Oncology Pharmacy Practice 2019, 26: 228-231. PMID: 30885040, DOI: 10.1177/1078155219836478.Peer-Reviewed Original ResearchConceptsOrthopedic malignanciesHypersensitivity reactionsEtoposide phosphatePediatric patientsEtoposide hypersensitivityLarge academic medical centerAcademic medical centerCase of etoposideContinued therapyChart reviewFurther therapyFirst dosesFull dosesEwing's sarcomaMedical CenterPatientsMalignancySafe alternativeEtoposideHypersensitivityTherapyDiphenhydramineDosesPremedicationSarcoma
2018
Preventable Anesthesia-Related Adverse Events at a Large Tertiary Care Center: A Nine-Year Retrospective Analysis
Curatolo CJ, McCormick PJ, Hyman JB, Beilin Y. Preventable Anesthesia-Related Adverse Events at a Large Tertiary Care Center: A Nine-Year Retrospective Analysis. The Joint Commission Journal On Quality And Patient Safety 2018, 44: 708-718. PMID: 30064954, DOI: 10.1016/j.jcjq.2018.03.013.Peer-Reviewed Original ResearchConceptsAdverse eventsNine-Year Retrospective AnalysisLarge tertiary care centerLarge tertiary care institutionPatient safetyPrimary adverse eventsMedication adverse eventsTertiary care centerTertiary care institutionLarge academic medical centerPreventable adverse eventsPerformance improvement committeeAcademic medical centerAdverse event typesPreventable anesthesiaUnplanned reintubationRespiratory complicationsPerioperative outcomesRetrospective reviewRespiratory arrestRespiratory eventsCare centerUnivariate analysisMedication eventsRetrospective analysis
2017
The Rothman Index as a predictor of postdischarge adverse events after elective spine surgery
McLynn RP, Ondeck NT, Cui JJ, Swanson DR, Shultz BN, Bovonratwet P, Grauer JN. The Rothman Index as a predictor of postdischarge adverse events after elective spine surgery. The Spine Journal 2017, 18: 1149-1156. PMID: 29155251, DOI: 10.1016/j.spinee.2017.11.008.Peer-Reviewed Original ResearchConceptsElective spine surgeryPostdischarge adverse eventsMinor adverse eventsMajor adverse eventsAdverse eventsRothman IndexSpine surgeryMedical CenterOverall patient conditionRothman Index scoresHigh-risk patientsRate of readmissionRetrospective cohort studyLarge academic medical centerPostoperative day 30Body mass indexLength of stayAcademic medical centerPresent studyElectronic medical recordsLater scoresAnesthesiologists classHospital lengthPerioperative outcomesCohort studyPre- and postoperative anemia, acute kidney injury, and mortality after coronary artery bypass grafting surgery: a retrospective observational study
Oprea AD, Del Rio JM, Cooter M, Green CL, Karhausen JA, Nailer P, Guinn NR, Podgoreanu MV, Stafford-Smith M, Schroder JN, Fontes ML, Kertai MD. Pre- and postoperative anemia, acute kidney injury, and mortality after coronary artery bypass grafting surgery: a retrospective observational study. Journal Canadien D'anesthésie 2017, 65: 46-59. PMID: 29098634, DOI: 10.1007/s12630-017-0991-0.Peer-Reviewed Original ResearchConceptsAcute kidney injuryPostoperative acute kidney injuryCoronary artery bypassPostoperative anemiaDay of surgerySerum hemoglobin concentrationPreoperative anemiaHemoglobin concentrationArtery bypassCABG surgeryKidney injuryGlobal Outcomes (KDIGO) Clinical Practice GuidelineIncidence of AKIMultivariable Cox proportional hazards analysisSingle large academic medical centerCox proportional hazards analysisPostoperative hemoglobin concentrationPostoperative hemoglobin levelsLong-term mortalityTenth postoperative dayProportional hazards analysisRetrospective observational studyLarge academic medical centerClinical practice guidelinesPotential risk factorsSurgical tray optimization as a simple means to decrease perioperative costs
Farrelly JS, Clemons C, Witkins S, Hall W, Christison-Lagay ER, Ozgediz DE, Cowles RA, Stitelman DH, Caty MG. Surgical tray optimization as a simple means to decrease perioperative costs. Journal Of Surgical Research 2017, 220: 320-326. PMID: 29180198, DOI: 10.1016/j.jss.2017.06.029.Peer-Reviewed Original ResearchConceptsSurgery sectionSingle-site observational studyHealth care cost reductionLarge academic medical centerHospital cost reductionCare cost reductionAcademic medical centerSurgical tray optimizationSurgical traysStudy startHealth care spendingSpine surgeryObservational studySurgical sectionMedical CenterPediatric surgeryPediatric surgeonsPerioperative costsAcademic centersUrology SectionOperating room nursingMultidisciplinary teamPediatric urologyPediatric orthopedicsScrub technicians
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