2025
CHAPTER 18 Remote monitoring of sleep apnea patients
Kongpakpaisarn K, Thapa S, Won C. CHAPTER 18 Remote monitoring of sleep apnea patients. 2025, 169-192. DOI: 10.1016/b978-0-323-87041-2.00027-0.Peer-Reviewed Original Research
2022
Sensorimotor Cortical Activity during Respiratory Arousals in Obstructive Sleep Apnea
Bahr-Hamm K, Koirala N, Hanif M, Gouveris H, Muthuraman M. Sensorimotor Cortical Activity during Respiratory Arousals in Obstructive Sleep Apnea. International Journal Of Molecular Sciences 2022, 24: 47. PMID: 36613490, PMCID: PMC9820672, DOI: 10.3390/ijms24010047.Peer-Reviewed Original ResearchConceptsModerate OSA patientsSevere OSASensorimotor cortical activityOSA patientsRespiratory arousalsCortical activityObstructive sleep apnea patientsSevere OSA patientsObstructive sleep apneaSignificant decreaseSleep apnea patientsSleep stagesRaw electroencephalography dataModerate OSASleep apneaRespiratory eventsApnea patientsDifferential diagnosisSleep stage N1PatientsAutonomic activationStage N1Cortical arousalPathophysiologic traitsOSACardiovascular Benefit of Continuous Positive Airway Pressure in Adults with Coronary Artery Disease and Obstructive Sleep Apnea without Excessive Sleepiness.
Azarbarzin A, Zinchuk A, Wellman A, Labarca G, Vena D, Gell L, Messineo L, White DP, Gottlieb DJ, Redline S, Peker Y, Sands SA. Cardiovascular Benefit of Continuous Positive Airway Pressure in Adults with Coronary Artery Disease and Obstructive Sleep Apnea without Excessive Sleepiness. American Journal Of Respiratory And Critical Care Medicine 2022, 206: 767-774. PMID: 35579605, PMCID: PMC9799106, DOI: 10.1164/rccm.202111-2608oc.Peer-Reviewed Original ResearchConceptsContinuous positive airway pressureObstructive sleep apneaAdverse cardiovascular outcomesPositive airway pressureCardiovascular outcomesAirway pressureCardiovascular benefitsCardiovascular riskSleep apneaExcessive sleepinessEffect of CPAPMultivariable Cox regressionProspective clinical trialsCoronary artery diseaseGreater cardiovascular benefitPulse rate responsesSignificant risk reductionCPAP therapyRepeat revascularizationBaseline polysomnographyCardiovascular mortalityArtery diseasePrimary outcomeCox regressionRespiratory eventsRespiratory Adverse Events After LMA® Mask Removal in Children: A Randomized Trial Comparing Propofol to Sevoflurane
Karam C, Zeeni C, Yazbeck-Karam V, Shebbo F, Khalili A, Raad S, Beresian J, Aouad M, Kaddoum R. Respiratory Adverse Events After LMA® Mask Removal in Children: A Randomized Trial Comparing Propofol to Sevoflurane. Anesthesia & Analgesia 2022, 136: 25-33. PMID: 35213484, DOI: 10.1213/ane.0000000000005945.Peer-Reviewed Original ResearchConceptsRespiratory adverse eventsTotal intravenous anesthesiaAdverse eventsEmergence agitationSecondary outcomesLower incidenceDouble-blind clinical trialPerioperative respiratory complicationsRemoval of LMALaryngeal mask airwayType of anesthesiaMinimal risk factorsQuality of anesthesiaLMA removalTIVA groupRespiratory complicationsHemodynamic stabilityLMA insertionMask airwaySevoflurane groupNatural airwayIntravenous anesthesiaPropofol inductionAdverse outcomesRespiratory events
2019
0670 Sleep-Related Event Physiologic Timing for Triggering Nonsustained Ventricular Tachycardia: A Case-crossover Analysis
May A, May R, Bena J, Wang L, Monahan K, Stone K, Barrett-Connor E, Koo B, Winkelman J, Redline S, Mittleman M, Mehra R. 0670 Sleep-Related Event Physiologic Timing for Triggering Nonsustained Ventricular Tachycardia: A Case-crossover Analysis. Sleep 2019, 42: a267-a268. DOI: 10.1093/sleep/zsz067.668.Peer-Reviewed Original ResearchRespiratory eventsSleep-related eventsHazard periodOsteoporotic fracturesOdds ratioBidirectional case-crossover designPeriodic limb movementsRespiratory-related arousalsConditional logistic regressionCase-crossover analysisCase-crossover designPhysiologic timingVentricular tachycardiaNSVTNSVT episodesPhysiologic effectsPLMSOlder menStudy participantsMan studyLogistic regressionLimb movementsSleepControl periodConfidence intervals0138 Physiological Effects of Respiratory Events that Terminate Without Arousals During Sleep
Liu J, Qin L, Yaggi H. 0138 Physiological Effects of Respiratory Events that Terminate Without Arousals During Sleep. Sleep 2019, 42: a56-a57. DOI: 10.1093/sleep/zsz067.137.Peer-Reviewed Original ResearchHigh-frequency EEG powerRespiratory eventsHeart rateTest-retest reliabilityCortical neural activityZ-scoreREM sleepRespiratory arousalsEEG powerCommunity-dwelling elderly menPoor cardiovascular outcomesObstructive sleep apneaNeural activityMean z-scoreStage 2 sleepExcellent test-retest reliabilityNon-REM sleepSignificant increaseCardiovascular outcomesCardiac effectsSympathetic surgeSleep apneaElderly menMrOS StudyFrequent arousals
2018
Preventable Anesthesia-Related Adverse Events at a Large Tertiary Care Center: A Nine-Year Retrospective Analysis
Curatolo CJ, McCormick PJ, Hyman JB, Beilin Y. Preventable Anesthesia-Related Adverse Events at a Large Tertiary Care Center: A Nine-Year Retrospective Analysis. The Joint Commission Journal On Quality And Patient Safety 2018, 44: 708-718. PMID: 30064954, DOI: 10.1016/j.jcjq.2018.03.013.Peer-Reviewed Original ResearchConceptsAdverse eventsNine-Year Retrospective AnalysisLarge tertiary care centerLarge tertiary care institutionPatient safetyPrimary adverse eventsMedication adverse eventsTertiary care centerTertiary care institutionLarge academic medical centerPreventable adverse eventsPerformance improvement committeeAcademic medical centerAdverse event typesPreventable anesthesiaUnplanned reintubationRespiratory complicationsPerioperative outcomesRetrospective reviewRespiratory arrestRespiratory eventsCare centerUnivariate analysisMedication eventsRetrospective analysis
2017
0720 ASSOCIATION OF INDIVIDUAL PERIODIC LIMB MOVEMENTS AND NON-SUSTAINED TACHYCARDIA DURING SLEEP: A CASE-CROSSOVER ANALYSIS
May A, May R, Bena J, Wang L, Monahan K, Stone K, Cawthon P, Barrett-Connor E, Koo B, Winkelman J, Redline S, Mittleman M, Mehra R. 0720 ASSOCIATION OF INDIVIDUAL PERIODIC LIMB MOVEMENTS AND NON-SUSTAINED TACHYCARDIA DURING SLEEP: A CASE-CROSSOVER ANALYSIS. Sleep 2017, 40: a266-a267. DOI: 10.1093/sleepj/zsx050.719.Peer-Reviewed Original ResearchPeriodic limb movementsRespiratory eventsOsteoporotic fracturesUnadjusted analysesNational InstituteSympathetic nervous system activationBidirectional case-crossover designLimb movementsControl periodNon-sustained tachycardiaApnea-hypopnea indexNervous system activationConditional logistic regressionVentricular tachycardia eventsCase-crossover analysisCase-crossover designAdvancing Translational SciencesPLMS indexBlood InstituteNational HeartTachycardia eventsVentricular arrhythmogenesisOdds ratioAncillary studiesNSVTThe impact of capnography monitoring among children and adolescents in the postanesthesia care unit: a randomized controlled trial
Langhan ML, Li F, Lichtor JL. The impact of capnography monitoring among children and adolescents in the postanesthesia care unit: a randomized controlled trial. Pediatric Anesthesia 2017, 27: 385-393. PMID: 28177565, DOI: 10.1111/pan.13077.Peer-Reviewed Original ResearchConceptsPostanesthesia care unitPulse oximetryRespiratory depressionAdverse eventsCare unitRespiratory eventsControl groupPediatric postanesthesia care unitAddition of capnographyRates of hypoxemiaAdverse respiratory eventsStaff interventionsPACU staffOxygen desaturationCapnography monitoringElective surgerySupplemental oxygenGeneral anesthesiaHealthy childrenIntervention groupPatient interventionsAbsence of interventionCapnography monitorStandard monitoringVital signs
2016
The Association between Nocturnal Cardiac Arrhythmias and Sleep-Disordered Breathing: The DREAM Study.
Selim BJ, Koo BB, Qin L, Jeon S, Won C, Redeker NS, Lampert RJ, Concato JP, Bravata DM, Ferguson J, Strohl K, Bennett A, Zinchuk A, Yaggi HK. The Association between Nocturnal Cardiac Arrhythmias and Sleep-Disordered Breathing: The DREAM Study. Journal Of Clinical Sleep Medicine 2016, 12: 829-37. PMID: 26951420, PMCID: PMC4877315, DOI: 10.5664/jcsm.5880.Peer-Reviewed Original ResearchConceptsSleep-disordered breathingNocturnal cardiac arrhythmiasIntraventricular conduction delayApnea-hypopnea indexCardiac arrhythmiasTwo-fold oddsModerate-severe sleep-disordered breathingSeverity of SDBSevere sleep-disordered breathingComplex ventricular ectopyMultiple cardiovascular comorbiditiesObstructive respiratory eventsClinic-based populationCross-sectional analysisCardiovascular comorbiditiesSDB patientsVentricular ectopySDB severityRespiratory eventsUnadjusted oddsSupraventricular tachycardiaCardiovascular diseaseArrhythmia subtypesArrhythmia riskConduction delay
2015
Infarct location and sleep apnea: evaluating the potential association in acute ischemic stroke
Stahl SM, Yaggi HK, Taylor S, Qin L, Ivan CS, Austin C, Ferguson J, Radulescu R, Tobias L, Sico J, Fragoso C, Williams LS, Lampert R, Miech EJ, Matthias MS, Kapoor J, Bravata DM. Infarct location and sleep apnea: evaluating the potential association in acute ischemic stroke. Sleep Medicine 2015, 16: 1198-1203. PMID: 26429745, PMCID: PMC4592521, DOI: 10.1016/j.sleep.2015.07.003.Peer-Reviewed Original ResearchConceptsObstructive sleep apneaApnea-hypopnea indexAcute ischemic strokeIschemic stroke patientsStroke patientsStroke locationOSA presenceIschemic strokeSleep apneaPrevalence of OSASeverity of OSAAcute ischemic stroke patientsTransient ischemic attackObstructive respiratory eventsMeasures of hypoxiaHigh overall prevalenceBrain imaging reportsIschemic attackPolysomnographic findingsOSA severityComplete polysomnographyRespiratory eventsInfarct locationOverall prevalenceVascular territories
2012
Respiratory Event Detection by a Positive Airway Pressure Device
Berry RB, Kushida CA, Kryger MH, Soto-Calderon H, Staley B, Kuna ST. Respiratory Event Detection by a Positive Airway Pressure Device. Sleep 2012, 35: 361-367. PMID: 22379242, PMCID: PMC3274337, DOI: 10.5665/sleep.1696.Peer-Reviewed Original ResearchConceptsObstructive sleep apneaEvents/hrPositive airway pressure devicesApnea indexHypopnea indexPAP devicesRespiratory eventsSleep disorders centerPressure deviceBetter treatment efficacyRespiratory event detectionOxygen desaturationSleep apneaPAP treatmentBland-Altman analysisDisorders CenterPolysomnographyTreatment efficacyAHIInadequate treatmentManual scoringHypopnea detectionTrue negative eventsHrTreatment
1995
Sleep apnea in patients with hemispheric stroke
Mohsenin V, Valor R. Sleep apnea in patients with hemispheric stroke. Archives Of Physical Medicine And Rehabilitation 1995, 76: 71-76. PMID: 7811179, DOI: 10.1016/s0003-9993(95)80046-8.Peer-Reviewed Original ResearchConceptsSleep-disordered breathingHemispheric strokeCerebral symptomsSleep apneaStroke patientsRapid eye movement (REM) sleepArterial oxygen desaturationComplications of strokePresence of hypertensionRespiratory disturbance indexBody mass indexAbnormal sleep architectureEye movement sleepSlow-wave sleepOxygen desaturationGroups of subjectsBrainstem lesionsCerebrovascular accidentCerebral strokeMass indexRespiratory disturbancesRespiratory eventsMovement sleepSleep architecturePrior history
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