2025
Incidence and risk factors for subthreshold insomnia among U.S. military veterans: a population-based, longitudinal study
Nichter B, Hill M, Fischer I, Na P, Schnakenberg Martin A, Worley C, Pietrzak R. Incidence and risk factors for subthreshold insomnia among U.S. military veterans: a population-based, longitudinal study. Sleep Medicine 2025, 132: 106581. PMID: 40403448, DOI: 10.1016/j.sleep.2025.106581.Peer-Reviewed Original ResearchConceptsSubthreshold insomniaRisk factorsHealth-related risk factorsPopulation-based longitudinal dataAt-risk veteransPhysical health outcomesPopulation-based sampleTargeted prevention strategiesU.S. veteran populationKey risk factorsU.S. military veteransDegree of distressHealth outcomesPopulation-basedMultiple predisposingVeteran populationEmployment statusClinical insomniaMilitary veteransPrevention strategiesChronic painVeteransSleep difficultiesAt-riskLongitudinal study
2024
Risk Factors for Pediatric Critical COVID-19: A Systematic Review and Meta-Analysis
Aparicio C, Willis Z, Nakamura M, Wolf J, Little C, Maron G, Sue P, Anosike B, Miller C, Bio L, Singh P, James S, Oliveira C. Risk Factors for Pediatric Critical COVID-19: A Systematic Review and Meta-Analysis. Journal Of The Pediatric Infectious Diseases Society 2024, 13: 352-362. PMID: 38780125, PMCID: PMC11519042, DOI: 10.1093/jpids/piae052.Peer-Reviewed Original ResearchOdds ratioCritical COVID-19Absolute riskMeta-analysisSystematic reviewRisk stratificationConfidence intervalsInvasive mechanical ventilation requirementRisk factorsEstimate pooled odds ratiosSignificant ORsKey risk factorsPooled odds ratioCritical diseaseIntensive care unit admissionStatistically significant ORsMechanical ventilation requirementRandom-effects modelRisk of critical diseaseChronic pulmonary conditionsHealth conditionsIndependent reviewersPooled ORInclusion criteriaCOVID-19
2023
Sialylated Glycan Bindings from SARS-CoV-2 Spike Protein to Blood and Endothelial Cells Govern the Severe Morbidities of COVID-19
Scheim D, Vottero P, Santin A, Hirsh A. Sialylated Glycan Bindings from SARS-CoV-2 Spike Protein to Blood and Endothelial Cells Govern the Severe Morbidities of COVID-19. International Journal Of Molecular Sciences 2023, 24: 17039. PMID: 38069362, PMCID: PMC10871123, DOI: 10.3390/ijms242317039.Peer-Reviewed Original ResearchConceptsSARS-CoV-2 spike proteinRed blood cellsCOVID-19Severe COVID-19 patientsSpike proteinSevere COVID-19COVID-19 correlatesCOVID-19 patientsCommon cold infectionsCOVID-19 morbidityLong-COVID patientsFuture therapeutic strategiesSARS-CoV-2Key risk factorsKey morbiditiesSurface of plateletsSevere morbidityClinical efficacyVascular damageViral loadMicrovascular occlusionRisk factorsCOVID patientsClinical studiesClinical susceptibilityAssessing the contributions of modifiable risk factors to serious falls and fragility fractures among older persons living with HIV
Womack J, Murphy T, Leo‐Summers L, Bates J, Jarad S, Gill T, Hsieh E, Rodriguez‐Barradas M, Tien P, Yin M, Brandt C, Justice A. Assessing the contributions of modifiable risk factors to serious falls and fragility fractures among older persons living with HIV. Journal Of The American Geriatrics Society 2023, 71: 1891-1901. PMID: 36912153, PMCID: PMC10258163, DOI: 10.1111/jgs.18304.Peer-Reviewed Original ResearchConceptsModifiable risk factorsFragility fracturesRisk factorsAlcohol use disorderSerious fallsPhysiologic frailtyAntiretroviral therapyOlder PWHUse disordersVeterans Aging Cohort StudyMeasures of multimorbidityAging Cohort StudyBody mass indexMultivariable logistic modelAverage attributable fractionSuccessful prevention programsKey risk factorsOpioid prescriptionsCohort studyMass indexModifiable factorsSixth decadeAttributable fractionElevated riskICD9 codesPrevalence of and risk factors for vertebral fracture and low bone mineral density among Peruvian women aging with HIV
Cabrera D, Cornejo M, Slotkin R, Pinedo Y, Yu W, Guan W, Garcia P, Hsieh E. Prevalence of and risk factors for vertebral fracture and low bone mineral density among Peruvian women aging with HIV. Archives Of Osteoporosis 2023, 18: 64. PMID: 37160770, PMCID: PMC10170032, DOI: 10.1007/s11657-023-01250-w.Peer-Reviewed Original ResearchConceptsBone mineral densityLow bone mineral densityThoracolumbar X-rayVertebral fracturesFemoral neckRisk factorsLumbar spineOsteoporosis treatmentTotal hipTreatment gapMineral densityTotal hip bone mineral densityPresence of VFsPeruvian womenTH bone mineral densityHip bone mineral densityFN bone mineral densityLower FN BMDSubset of patientsGenant semiquantitative methodLower femoral neckImportant treatment gapsKey risk factorsAntiretroviral therapyFRAX score
2022
Modulation of the Association Between Age and Death by Risk Factor Burden in Critically Ill Patients With COVID-19
Sunderraj A, Cho C, Cai X, Gupta S, Mehta R, Isakova T, Leaf D, Srivastava A, Walther C, Anumudu S, Arunthamakun J, Kopecky K, Milligan G, McCullough P, Nguyen T, Shaefi S, Krajewski M, Shankar S, Pannu A, Valencia J, Waikar S, Kibbelaar Z, Athavale A, Hart P, Upadhyay S, Vohra I, Oyintayo A, Green A, Rachoin J, Schorr C, Shea L, Edmonston D, Mosher C, Shehata A, Cohen Z, Allusson V, Bambrick-Santoyo G, Bhatti N, Mehta B, Williams A, Brenner S, Walters P, Go R, Rose K, Hernán M, Zhou A, Kim E, Lisk R, Chan L, Mathews K, Coca S, Altman D, Saha A, Soh H, Wen H, Bose S, Leven E, Wang J, Mosoyan G, Nadkarni G, Pattharanitima P, Gallagher E, Friedman A, Guirguis J, Kapoor R, Meshberger C, Kelly K, Parikh C, Garibaldi B, Corona-Villalobos C, Wen Y, Menez S, Malik R, Cervantes C, Gautam S, Mallappallil M, Ouyang J, John S, Yap E, Melaku Y, Mohamed I, Bajracharya S, Puri I, Thaxton M, Bhattacharya J, Wagner J, Boudourakis L, Nguyen H, Ahoubim A, Thomas L, Sirganagari D, Guru P, Kashani K, Tehranian S, Zhou Y, Bergl P, Rodriguez J, Shah J, Gupta M, Kumar P, Lazarous D, Kassaye S, Melamed M, Johns T, Mocerino R, Prudhvi K, Zhu D, Levy R, Azzi Y, Fisher M, Yunes M, Sedaliu K, Golestaneh L, Brogan M, Kumar N, Chang M, Thakkar J, Raichoudhury R, Athreya A, Farag M, Schenck E, Cho S, Plataki M, Alvarez-Mulett S, Gomez-Escobar L, Pan D, Lee S, Krishnan J, Whalen W, Charytan D, Macina A, Chaudhry S, Wu B, Modersitzki F, Srivastava A, Leidner A, Martinez C, Kruser J, Wunderink R, Hodakowski A, Velez J, Price-Haywood E, Matute-Trochez L, Hasty A, Mohamed M, Avasare R, Zonies D, Leaf D, Gupta S, Sise M, Newman E, Abu Omar S, Pokharel K, Sharma S, Singh H, Correa S, Shaukat T, Kamal O, Wang W, Yang H, Boateng J, Lee M, Strohbehn I, Li J, Mueller A, Redfern R, Cairl N, Naimy G, Abu-Saif A, Hall D, Bickley L, Rowan C, Madhani-Lovely F, Cruz V, Hess K, Jacobs A, Peev V, Reiser J, Byun J, Vissing A, Kapania E, Post Z, Patel N, Hermes J, Sutherland A, Patrawalla A, Finkel D, Danek B, Arikapudi S, Paer J, Cangialosi P, Liotta M, Radbel J, Puri S, Sunderram J, Scharf M, Ahmed A, Berim I, Vatson J, Anand S, Levitt J, Garcia P, Boyle S, Song R, Zhang J, Woo S, Deng X, Katz-Greenberg G, Senter K, Sharshir M, Rusnak V, Ali M, Bansal A, Podoll A, Chonchol M, Sharma S, Burnham E, Douin D, Rashidi A, Hejal R, Judd E, Latta L, Tolwani A, Albertson T, Adams J, Chang S, Beutler R, Schulze C, Macedo E, Rhee H, Liu K, Jotwani V, Koyner J, Shah C, Jaikaransingh V, Toth-Manikowski S, Joo M, Lash J, Neyra J, Chaaban N, Elias M, Ahmad Y, Iardino A, Au E, Sharma J, Sosa M, Taldone S, Contreras G, De La Zerda D, Gershengorn H, Shukla B, Fornoni A, Ferreira T, Hayek S, Blakely P, Berlin H, Azam T, Shadid H, Pan M, Hayer P, Meloche C, Feroze R, Kaakati R, Perry D, Bitar A, Anderson E, Padalia K, Donnelly J, Admon A, Flythe J, Tugman M, Chang E, Brown B, Leonberg-Yoo A, Spiardi R, Miano T, Roche M, Vasquez C, Bansal A, Ernecoff N, Kapoor S, Verma S, Chen H, Kovesdy C, Molnar M, Azhar A, Hedayati S, Nadamuni M, Shastri S, Willett D, Short S, Renaghan A, Enfield K, Bhatraju P, Malik A, Semler M, Vijayan A, Joy C, Li T, Goldberg S, Kao P, Schumaker G, Goyal N, Faugno A, Schumaker G, Hsu C, Tariq A, Meyer L, Kshirsagar R, Weiner D, Jose A, Christov M, Griffiths J, Gupta S, Kapoor A, Wilson P, Arora T, Ugwuowo U. Modulation of the Association Between Age and Death by Risk Factor Burden in Critically Ill Patients With COVID-19. Critical Care Explorations 2022, 4: e0755. PMID: 36050992, PMCID: PMC9426819, DOI: 10.1097/cce.0000000000000755.Peer-Reviewed Original ResearchICU factorsIll patientsRisk factorsEffect modificationCOVID-19Older ageRisk factor burdenCritically ill patientsMulticenter cohort studyMultivariable logistic regressionRisk of deathLogistic regression modelsKey risk factorsInhospital mortalityCohort studyMultiplicative interaction termIll adultsPrimary outcomeAdverse outcomesPrimary exposureICU bedsComorbiditiesPatientsLogistic regressionAdditional studiesAge–sex differences in the global burden of lower respiratory infections and risk factors, 1990–2019: results from the Global Burden of Disease Study 2019
Collaborators G, Kyu H, Vongpradith A, Sirota S, Novotney A, Troeger C, Doxey M, Bender R, Ledesma J, Biehl M, Albertson S, Frostad J, Burkart K, Bennitt F, Zhao J, Gardner W, Hagins H, Bryazka D, Dominguez R, Abate S, Abdelmasseh M, Abdoli A, Abdoli G, Abedi A, Abedi V, Abegaz T, Abidi H, Aboagye R, Abolhassani H, Abtew Y, Ali H, Abu-Gharbieh E, Abu-Zaid A, Adamu K, Addo I, Adegboye O, Adnan M, Adnani Q, Afzal M, Afzal S, Ahinkorah B, Ahmad A, Ahmad A, Ahmad S, Ahmadi A, Ahmadi S, Ahmed H, Ahmed J, Rashid T, Akbarzadeh-Khiavi M, Al Hamad H, Albano L, Aldeyab M, Alemu B, Alene K, Algammal A, Alhalaiqa F, Alhassan R, Ali B, Ali L, Ali M, Ali S, Alimohamadi Y, Alipour V, Al-Jumaily A, Aljunid S, Almustanyir S, Al-Raddadi R, Al-Rifai R, AlRyalat S, Alvis-Guzman N, Alvis-Zakzuk N, Ameyaw E, Dehkordi J, Amuasi J, Amugsi D, Anbesu E, Ansar A, Anyasodor A, Arabloo J, Areda D, Argaw A, Argaw Z, Arulappan J, Aruleba R, Asemahagn M, Athari S, Atlaw D, Attia E, Attia S, Aujayeb A, Awoke T, Ayana T, Ayanore M, Azadnajafabad S, Azangou-Khyavy M, Azari S, Jafari A, Badar M, Badiye A, Baghcheghi N, Bagherieh S, Baig A, Banach M, Banerjee I, Bardhan M, Barone-Adesi F, Barqawi H, Barrow A, Bashiri A, Bassat Q, Batiha A, Belachew A, Belete M, Belgaumi U, Bhagavathula A, Bhardwaj N, Bhardwaj P, Bhatt P, Bhojaraja V, Bhutta Z, Bhuyan S, Bijani A, Bitaraf S, Bodicha B, Briko N, Buonsenso D, Butt M, Cai J, Camargos P, Cámera L, Chakraborty P, Chanie M, Charan J, Chattu V, Ching P, Choi S, Chong Y, Choudhari S, Chowdhury E, Christopher D, Chu D, Cobb N, Cohen A, Cruz-Martins N, Dadras O, Dagnaw F, Dai X, Dandona L, Dandona R, Dao A, Debela S, Demisse B, Demisse F, Demissie S, Dereje D, Desai H, Desta A, Desye B, Dhingra S, Diao N, Diaz D, Digesa L, Doan L, Dodangeh M, Dongarwar D, Dorostkar F, dos Santos W, Dsouza H, Dubljanin E, Durojaiye O, Edinur H, Ehsani-Chimeh E, Eini E, Ekholuenetale M, Ekundayo T, Desouky E, Sayed I, Zaki M, Elhadi M, Elkhapery A, Emami A, Bain L, Erkhembayar R, Etaee F, Asar M, Fagbamigbe A, Falahi S, Fallahzadeh A, Faraj A, Faraon E, Fatehizadeh A, Ferrara P, Ferrari A, Fetensa G, Fischer F, Flavel J, Foroutan M, Gaal P, Gaidhane A, Gaihre S, Galehdar N, Garcia-Basteiro A, Garg T, Gebrehiwot M, Gebremichael M, Gela Y, Gemeda B, Gessner B, Getachew M, Getie A, Ghamari S, Nour M, Ghashghaee A, Gholamrezanezhad A, Gholizadeh A, Ghosh R, Ghozy S, Goleij P, Golitaleb M, Gorini G, Goulart A, Goyomsa G, Guadie H, Gudisa Z, Guled R, Gupta S, Gupta V, Gupta V, Guta A, Habibzadeh P, Haj-Mirzaian A, Halwani R, Hamidi S, Hannan A, Harorani M, Hasaballah A, Hasani H, Hassan A, Hassani S, Hassanian-Moghaddam H, Hassankhani H, Hayat K, Heibati B, Heidari M, Heyi D, Hezam K, Holla R, Hong S, Horita N, Hosseini M, Hosseinzadeh M, Hostiuc M, Househ M, Hoveidamanesh S, Huang J, Hussein N, Iavicoli I, Ibitoye S, Ikuta K, Ilesanmi O, Ilic I, Ilic M, Immurana M, Ismail N, Iwagami M, Jaafari J, Jamshidi E, Jang S, Mamaghani A, Javaheri T, Javanmardi F, Javidnia J, Jayapal S, Jayarajah U, Jayaram S, Jema A, Jeong W, Jonas J, Joseph N, Joukar F, Jozwiak J, Vaishali K, Kabir Z, Kacimi S, Kadashetti V, Kalankesh L, Kalhor R, Kamath A, Kamble B, Kandel H, Kanko T, Karaye I, Karch A, Karkhah S, Kassa B, Katoto P, Kaur H, Kaur R, Keikavoosi-Arani L, Keykhaei M, Khader Y, Khajuria H, Khan E, Khan G, Khan I, Khan M, Khan N, Khan M, Khan Y, Khatatbeh M, Khosravifar M, Khubchandani J, Kim M, Kimokoti R, Kisa A, Kisa S, Kissoon N, Knibbs L, Kochhar S, Kompani F, Koohestani H, Korshunov V, Kosen S, Koul P, Koyanagi A, Krishan K, Defo B, Kumar G, Kurmi O, Kuttikkattu A, Lal D, Lám J, Landires I, Ledda C, Lee S, Levi M, Lewycka S, Liu G, Liu W, Lodha R, Lorenzovici L, Lotfi M, Loureiro J, Madadizadeh F, Mahmoodpoor A, Mahmoudi R, Mahmoudimanesh M, Majidpoor J, Makki A, Rad E, Malik A, Mallhi T, Manla Y, Matei C, Mathioudakis A, Maude R, Nasab E, Melese A, Memish Z, Mendoza-Cano O, Mentis A, Meretoja T, Merid M, Mestrovic T, de Sá A, Mijena G, Minh L, Mir S, Mirfakhraie R, Mirmoeeni S, Mirza A, Mirza M, Mirza-Aghazadeh-Attari M, Misganaw A, Misganaw A, Mohammadi E, Mohammadi M, Mohammed A, Mohammed S, Mohan S, Mohseni M, Moka N, Mokdad A, Momtazmanesh S, Monasta L, Moniruzzaman, Montazeri F, Moore C, Moradi A, Morawska L, Mosser J, Mostafavi E, Motaghinejad M, Isfahani H, Mousavi-Aghdas S, Mubarik S, Murillo-Zamora E, Mustafa G, Nair S, Nair T, Najafi H, Naqvi A, Swamy S, Natto Z, Nayak B, Nejadghaderi S, Van Nguyen Nguyen H, Niazi R, de Sá A, Nouraei H, Nowroozi A, Nuñez-Samudio V, Nzoputam C, Nzoputam O, Oancea B, Ochir C, Odukoya O, Okati-Aliabad H, Okekunle A, Okonji O, Olagunju A, Olufadewa I, Bali A, Omer E, Oren E, Ota E, Otstavnov N, Oulhaj A, Mahesh P, Padubidri J, Pakshir K, Pakzad R, Palicz T, Pandey A, Pant S, Pardhan S, Park E, Park E, Kan F, Paudel R, Pawar S, Peng M, Pereira G, Perna S, Perumalsamy N, Petcu I, Pigott D, Piracha Z, Podder V, Polibin R, Postma M, Pourasghari H, Pourtaheri N, Qadir M, Raad M, Rabiee M, Rabiee N, Raeghi S, Rafiei A, Rahim F, Rahimi M, Rahimi-Movaghar V, Rahman A, Rahman O, Rahman M, Rahman M, Rahmani A, Rahmanian V, Ram P, Ramezanzadeh K, Rana J, Ranasinghe P, Rani U, Rao S, Rashedi S, Rashidi M, Rasul A, Ratan Z, Rawaf D, Rawaf S, Rawassizadeh R, Razeghinia M, Redwan E, Reitsma M, Renzaho A, Rezaeian M, Riad A, Rikhtegar R, Rodriguez J, Rogowski E, Ronfani L, Rudd K, Saddik B, Sadeghi E, Saeed U, Safary A, Safi S, Sahebazzamani M, Sahebkar A, Sakhamuri S, Salehi S, Salman M, Kafil H, Samy A, Santric-Milicevic M, Jose B, Sarkhosh M, Sathian B, Sawhney M, Saya G, Seidu A, Seylani A, Shaheen A, Shaikh M, Shaker E, Shamshad H, Sharew M, Sharhani A, Sharifi A, Sharma P, Sheidaei A, Shenoy S, Shetty J, Shiferaw D, Shigematsu M, Shin J, Shirzad-Aski H, Shivakumar K, Shivalli S, Shobeiri P, Simegn W, Simpson C, Singh H, Singh J, Singh P, Siwal S, Skryabin V, Skryabina A, Soltani-Zangbar M, Song S, Song Y, Sood P, Sreeramareddy C, Steiropoulos P, Suleman M, Tabatabaeizadeh S, Tahamtan A, Taheri M, Soodejani M, Taki E, Talaat I, Tampa M, Tandukar S, Tat N, Tat V, Tefera Y, Temesgen G, Temsah M, Tesfaye A, Tesfaye D, Tessema B, Thapar R, Ticoalu J, Tiyuri A, Tleyjeh I, Togtmol M, Tovani-Palone M, Tufa D, Ullah I, Upadhyay E, Tahbaz S, Valdez P, Valizadeh R, Vardavas C, Vasankari T, Vo B, Vu L, Wagaye B, Waheed Y, Wang Y, Waris A, West T, Wickramasinghe N, Xu X, Yaghoubi S, Yahya G, Jabbari S, Yon D, Yonemoto N, Zaman B, Zandifar A, Zangiabadian M, Zar H, Zare I, Zareshahrabadi Z, Zarrintan A, Zastrozhin M, Zeng W, Zhang M, Zhang Z, Zhong C, Zoladl M, Zumla A, Lim S, Vos T, Naghavi M, Brauer M, Hay S, Murray C. Age–sex differences in the global burden of lower respiratory infections and risk factors, 1990–2019: results from the Global Burden of Disease Study 2019. The Lancet Infectious Diseases 2022, 22: 1626-1647. PMID: 35964613, PMCID: PMC9605880, DOI: 10.1016/s1473-3099(22)00510-2.Peer-Reviewed Original ResearchConceptsLower respiratory infectionsLRI deathsRisk factorsHousehold air pollutionGlobal burdenAge groupsRespiratory infectionsInternational ClassificationMortality rateChild wastingVital registration dataRisk Factors Study (GBD) 2019Bayesian meta-regression toolClinician-diagnosed pneumoniaDisMod-MR 2.1Age-standardised incidenceDisease Study 2019Population-based survey dataMortality surveillance dataVerbal autopsy dataAdult age groupsReduction of exposureKey risk factorsAmbient particulate matter pollutionRegistration dataDevelopment of a Prediction Model for COVID‐19 Acute Respiratory Distress Syndrome in Patients With Rheumatic Diseases: Results From the Global Rheumatology Alliance Registry
Izadi Z, Gianfrancesco M, Aguirre A, Strangfeld A, Mateus E, Hyrich K, Gossec L, Carmona L, Lawson‐Tovey S, Kearsley‐Fleet L, Schaefer M, Seet A, Schmajuk G, Jacobsohn L, Katz P, Rush S, Al‐Emadi S, Sparks J, Hsu T, Patel N, Wise L, Gilbert E, Duarte‐García A, Valenzuela‐Almada M, Ugarte‐Gil M, Ribeiro S, de Oliveira Marinho A, de Azevedo Valadares L, Di Giuseppe D, Hasseli R, Richter J, Pfeil A, Schmeiser T, Isnardi C, Torres A, Alle G, Saurit V, Zanetti A, Carrara G, Labreuche J, Barnetche T, Herasse M, Plassart S, Santos M, Rodrigues A, Robinson P, Machado P, Sirotich E, Liew J, Hausmann J, Sufka P, Grainger R, Bhana S, Costello W, Wallace Z, Yazdany J, Registry G. Development of a Prediction Model for COVID‐19 Acute Respiratory Distress Syndrome in Patients With Rheumatic Diseases: Results From the Global Rheumatology Alliance Registry. ACR Open Rheumatology 2022, 4: 872-882. PMID: 35869686, PMCID: PMC9350083, DOI: 10.1002/acr2.11481.Peer-Reviewed Original ResearchAcute respiratory distress syndromeRisk score calculatorCOVID-19 acute respiratory distress syndromeRespiratory distress syndromeScore calculatorCOVID-19 diagnosisDistress syndromeRheumatic diseasesCoronavirus disease 2019 acute respiratory distress syndromeIndependent registriesCOVID-19 disease progressionRegression modelsKey risk factorsRisk stratificationARDS outcomeRisk factorsDisease progressionHighest mean AUCHigh riskPatientsMean AUCClinical settingRegistryMonoclonal antibodiesSyndrome
2021
Predictors of vaping marijuana initiation among US adolescents: Results from the Population Assessment of Tobacco and Health (PATH) study Wave 3 (2015–2016) and Wave 4 (2016–2018)
Lee J, Kong G, Kassas B, Salloum RG. Predictors of vaping marijuana initiation among US adolescents: Results from the Population Assessment of Tobacco and Health (PATH) study Wave 3 (2015–2016) and Wave 4 (2016–2018). Drug And Alcohol Dependence 2021, 226: 108905. PMID: 34304122, DOI: 10.1016/j.drugalcdep.2021.108905.Peer-Reviewed Original ResearchConceptsElectronic nicotine delivery systemsRisk factorsProduct use-associated lung injuryUse-associated lung injuryUS adolescentsMultivariable logistic regressionPublic health levelWave 3Public health concernNicotine delivery systemsKey risk factorsWave 4Lung injuryRisk individualsE-cigarettesLogistic regressionHealth concernSubstance usePopulation AssessmentYouth substance useMulti-level effortsHealth levelMarijuanaMarijuana initiationAdolescentsPsychological trauma and the genetic overlap between posttraumatic stress disorder and major depressive disorder
Mundy J, Hübel C, Gelernter J, Levey D, Murray RM, Skelton M, Stein MB, Maihofer A, Nievergelt C, Baker D, Risborough V, Calabrese J, Galea S, Stein D, Koen N, Dalvie S, Aiello A, Roberts A, Koenen K, Solovieff N, Kranzler H, Zhao H, Gelernter J, Farrer L, Johnson E, Rice J, Bierut L, Saccone N, McFarlane A, Forbes D, Silove D, O'Donnell M, Bryant R, van Hooff M, Sponheim S, Disner S, Pietrzak R, Chen C, Smoller J, Stein M, Ursano R, Kessler R, Junglen A, Delahanty D, Amstadter A, Sheerin C, Ruggiero K, McLaughlin K, Peverill M, Caldas-de-Almeida J, Austin S, Gelaye B, Williams M, Sanchez S, Franz C, Panizzon M, Lyons M, Kremen W, Andreassen O, Dale A, Rutten B, Vinkers C, Schijven D, Geuze E, Vermetten E, Luykx J, Boks M, Ashley-Koch A, Beckham J, Garrett M, Hauser M, Dennis M, Kimbrel N, Qin X, Karstoft K, Andersen S, Borglum A, Hougaard D, Bybjerg-Grauholm J, Duncan L, Bµkvad-Hansen M, Nordentoft M, Mors O, Mortensen P, Werge T, Thompson W, Wang Y, Heath A, Nelson E, Martin N, Gordon S, Wolf E, Logue M, Miller M, McGlinchey R, Milberg W, Erbes C, Polusny M, Arbisi P, Peterson A, Williamson D, Young K, Maurer D, Rothbaum A, Zoellner L, Mavissakalian M, Feeny N, Roy-Byrne P, Rothbaum B, Maples-Keller J, Khan A, Wolff J, Lebois L, Teicher M, Kaufman M, Winternitz S, Bolger E, Seligowski A, Orcutt H, Evans A, Lugonja B, Lewis C, Jones I, Bisson J, McLean S, Linnstaedt S, Peters E, Rung A, Trapido E, Brashear M, Lori A, Smith A, Bradley B, Gillespie C, Guffanti G, Ressler K, Almli L, Jovanovic T, Bustamante A, Uddin M, van den Heuvel L, Seedat S, Hemmings S, Uka A, Kulenovic A, Wolf C, Babic D, Avdibegovic E, Deckert J, Domschke K, Jakovljevic M, Marmar C, Flory J, Jett M, Yehuda R, Hammamieh R, King A, Liberzon I, Seng J, Morris C, Mehta D, Voisey J, Lawford B, Young R, McLeay S, Daskalakis N, Norman S, Wang Z, Breen G, Coleman J, Klengel T, Torres K, Choi K, Levey D, Polimanti R, Atkinson E, Martin A, Neale B, Daly M, Ripke S, Ratanatharathorn A, Provost A, Haas M, Stevens J, Morey R, Harnal S, Mortensen P, Seedat S, Sumner J, Vassos E, Breen G, Coleman J. Psychological trauma and the genetic overlap between posttraumatic stress disorder and major depressive disorder. Psychological Medicine 2021, 52: 3975-3984. PMID: 34085609, PMCID: PMC8962503, DOI: 10.1017/s0033291721000830.Peer-Reviewed Original ResearchRecurrent major depressive disorderMajor depressive disorderPosttraumatic stress disorderSingle-episode major depressive disorderDepressive disorderTrauma exposureStress disorderPsychological trauma exposureLifetime major depressive disorderTrauma sensitivityGenetic loadingUK Biobank participantsKey risk factorsMental health consequencesRisk factorsMillion Veteran ProgramPolygenic risk scoresRisk scoreGenetic overlapHealth consequencesBiobank participantsTraumaDisordersVeteran ProgramPsychiatric Genomics ConsortiumChanges in trabecular bone score and bone mineral density in Chinese HIV-Infected individuals after one year of antiretroviral therapy
Guan WM, Pan W, Yu W, Cao W, Lin Q, Zhang ZZ, Song XJ, Li YL, Tian JP, Xu Y, Li TS, Hsieh E. Changes in trabecular bone score and bone mineral density in Chinese HIV-Infected individuals after one year of antiretroviral therapy. Journal Of Orthopaedic Translation 2021, 29: 72-77. PMID: 34094860, PMCID: PMC8164002, DOI: 10.1016/j.jot.2021.04.002.Peer-Reviewed Original ResearchTrabecular bone scoreBone mineral densityDual-energy X-ray absorptiometryLPV/rAntiretroviral therapyART initiationLower BMIBone scoreRisk factorsMineral densityBone microarchitectureBaseline TBSHuman immunodeficiency virus (HIV) infectionNormal bone mineral densityBone damageDifferent antiretroviral agentsHIV treatment historyImpaired bone microarchitectureLower baseline CD4Immunodeficiency virus infectionTraditional risk factorsClinicians additional informationX-ray absorptiometryKey risk factorsBaseline CD4
2020
Early discontinuation of pharmacotherapy in U.S. veterans diagnosed with PTSD and the role of psychotherapy
Duek O, Pietrzak RH, Petrakis I, Hoff R, Harpaz-Rotem I. Early discontinuation of pharmacotherapy in U.S. veterans diagnosed with PTSD and the role of psychotherapy. Journal Of Psychiatric Research 2020, 132: 167-173. PMID: 33126010, DOI: 10.1016/j.jpsychires.2020.10.005.Peer-Reviewed Original ResearchConceptsPosttraumatic stress disorderRisk factorsEarly discontinuationMedication discontinuationPsychotropic medicationsPoor medication adherenceSimilar risk factorsStrong risk factorDeterminants of discontinuationKey risk factorsRole of psychotherapySingle medicationMedication adherenceMedication treatmentPsychiatric comorbidityAntipsychotic medicationPatient educationDiscontinuationOlder veteransMedicationsAdjunctive psychotherapyYounger veteransEarly interventionU.S. veteransVA treatmentThe Pre-exposure Prophylaxis (PrEP) Care Cascade in People Who Inject Drugs: A Systematic Review
Mistler CB, Copenhaver MM, Shrestha R. The Pre-exposure Prophylaxis (PrEP) Care Cascade in People Who Inject Drugs: A Systematic Review. AIDS And Behavior 2020, 25: 1490-1506. PMID: 32749627, PMCID: PMC7858689, DOI: 10.1007/s10461-020-02988-x.Peer-Reviewed Original ResearchConceptsPre-exposure prophylaxisCare cascadeSystematic reviewInjection drug useTransmission of HIVKey risk factorsPrEP eligibilityPrEP carePrEP uptakeHIV incidenceHIV transmissionRisk factorsPRISMA guidelinesPrevention strategiesPWIDDrug useLiterature searchEfficacious strategyProphylaxisPrEPDrugsInterventionHigh awarenessHIVReview
2019
Polypharmacy, Hazardous Alcohol and Illicit Substance Use, and Serious Falls Among PLWH and Uninfected Comparators.
Womack JA, Murphy TE, Rentsch CT, Tate JP, Bathulapalli H, Smith AC, Bates J, Jarad S, Gibert CL, Rodriguez-Barradas MC, Tien PC, Yin MT, Gill TM, Friedlaender G, Brandt CA, Justice AC. Polypharmacy, Hazardous Alcohol and Illicit Substance Use, and Serious Falls Among PLWH and Uninfected Comparators. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2019, 82: 305-313. PMID: 31339866, PMCID: PMC7176040, DOI: 10.1097/qai.0000000000002130.Peer-Reviewed Original ResearchConceptsIllicit substance useHazardous alcoholSerious fallsUninfected comparatorsMedication classesOpioid prescriptionsSubstance useHIV statusMuscle relaxantsRisk factorsVeterans Aging Cohort StudyAging Cohort StudyIllicit substance abuseUnconditional logistic regressionNon-ART medicationsHazardous alcohol useSubstance use/abuseCase-control designKey risk factorsUse/abuseCohort studyMedication countInjury codesDuration of observationBaseline dateRisk factors for chemotherapy‐induced peripheral neuropathy in patients receiving taxane‐ and platinum‐based chemotherapy
Molassiotis A, Cheng H, Leung K, Li Y, Wong K, Au J, Sundar R, Chan A, De Ng T, Suen L, Chan C, Yorke J, Lopez V. Risk factors for chemotherapy‐induced peripheral neuropathy in patients receiving taxane‐ and platinum‐based chemotherapy. Brain And Behavior 2019, 9: e01312. PMID: 31063261, PMCID: PMC6576180, DOI: 10.1002/brb3.1312.Peer-Reviewed Original ResearchConceptsChemotherapy-induced peripheral neuropathyDevelopment of chemotherapy-induced peripheral neuropathyHistory of neuropathyRisk factorsPeripheral neuropathyPlatinum-based chemotherapySymptom burdenPotential risk factorsVegetable/fruit intakeWHO criteriaChemotherapy cyclesAlcohol intakeSmoking historyUnivariate analysisChemotherapyMultivariate regression modelMedical historyTreatment characteristicsNeurotoxic chemotherapyKey risk factorsNeuropathyCancer CenterSide effectsQuality of lifeTreatment decisionsExploring temporal suicidal behavior patterns on social media: Insight from Twitter analytics
Luo J, Du J, Tao C, Xu H, Zhang Y. Exploring temporal suicidal behavior patterns on social media: Insight from Twitter analytics. Health Informatics Journal 2019, 26: 738-752. PMID: 30866708, DOI: 10.1177/1460458219832043.Peer-Reviewed Original ResearchConceptsRisk factorsDifferent risk factorsPotential suicidal ideationPublic health servicesKey risk factorsSuicide-related tweetsPrevention strategiesHealth servicesSuicidal ideationSuicide behaviorSuicide detectionSuicide ratesDifferent daysWider populationTemporal patternsBehavior patternsPopulationFactorsWeeks
2014
Double disadvantage: the influence of childhood maltreatment and community violence exposure on adolescent mental health
Cecil C, Viding E, Barker E, Guiney J, McCrory E. Double disadvantage: the influence of childhood maltreatment and community violence exposure on adolescent mental health. Journal Of Child Psychology And Psychiatry 2014, 55: 839-848. PMID: 24611776, DOI: 10.1111/jcpp.12213.Peer-Reviewed Original ResearchConceptsCommunity violence exposureTrauma-related symptomsRisk factorsChildhood maltreatmentCommunity violenceMental healthChildhood maltreatment exposureViolence exposureForms of adversityMental health domainsEnvironmental risk factorsMental health functioningKey risk factorsMental health outcomesAdolescent mental healthClinical symptomsHigh-risk adolescentsIndependent associationHealth functioningHealth outcomesSymptomsMaltreatment exposureYoung adultsHealth domainsLatent profile analysis
2012
The Epidemiology of Acute Stress Disorder and Other Early Responses to Trauma in Adults
Biggs Q, Guimond J, Fullerton C, Ursano R, Gray C, Goldenberg M, Reissman D, McCarroll J, Santiago P, Tyler M. The Epidemiology of Acute Stress Disorder and Other Early Responses to Trauma in Adults. 2012, 69-83. DOI: 10.1093/oxfordhb/9780195399066.013.0006.Peer-Reviewed Original ResearchPosttraumatic stress disorderAcute stress disorderStress disorderAnxiety disordersPopulation-based studySubstance use disordersBrief durationKey risk factorsRisk factorsFemale genderSelect populationEpidemiological studiesUse disordersSmall studySocioeconomic statusDisordersMarital statusAccident victimsASD prevalenceEarly responseFemale sexual assault victimsSexual assault victimsPrevalencePeritraumatic dissociationTraumatic events
2011
Mental health of displaced and refugee children resettled in high-income countries: risk and protective factors
Fazel M, Reed RV, Panter-Brick C, Stein A. Mental health of displaced and refugee children resettled in high-income countries: risk and protective factors. The Lancet 2011, 379: 266-282. PMID: 21835459, DOI: 10.1016/s0140-6736(11)60051-2.Peer-Reviewed Original ResearchConceptsHigh-income countriesProtective factorsMental healthKey risk factorsMental health vulnerabilitiesRisk factorsRapid resolutionAdverse exposuresPsychological functioningPsychological symptomsSystematic searchRefugee childrenHealth vulnerabilityLongitudinal investigationSocial supportChildrenReview of individualsChildren's psychological functioningRiskHealthExposureFurther researchSymptomsResearch designFactors
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