2023
THU603 Bone Fragility In Mild Autonomous Cortisol Secretion: A Cross-Sectional Cohort Study
Zhang C, Singh S, Saini J, Suresh M, Thangamuthu K, Nathani R, Ebbehøj A, Fell V, Achenbach S, Atkinson E, Khosla S, Bancos I. THU603 Bone Fragility In Mild Autonomous Cortisol Secretion: A Cross-Sectional Cohort Study. Journal Of The Endocrine Society 2023, 7: bvad114.133. PMCID: PMC10554138, DOI: 10.1210/jendso/bvad114.133.Peer-Reviewed Original ResearchTrabecular bone scoreBone mineral densityDual-energy X-ray absorptiometryAutonomous cortisol secretionBone turnover markersAdrenal nodulesReference subjectsTurnover markersHR-pQCTBone massBone metabolismDecreased TBSTrabecular volumetric bone mineral densityCross-sectional single-center studyMedian age of study participantsOvernight dexamethasone suppression testCortisol secretionVolumetric bone mineral densityAnalysis of bone turnover markersNon-dominant radiusHigh-resolution peripheral quantitative computed tomographyCross-sectional cohort studySingle-center studyAge of study participantsIncreased fracture risk
2021
Changes in trabecular bone score and bone mineral density in Chinese HIV-Infected individuals after one year of antiretroviral therapy
Guan WM, Pan W, Yu W, Cao W, Lin Q, Zhang ZZ, Song XJ, Li YL, Tian JP, Xu Y, Li TS, Hsieh E. Changes in trabecular bone score and bone mineral density in Chinese HIV-Infected individuals after one year of antiretroviral therapy. Journal Of Orthopaedic Translation 2021, 29: 72-77. PMID: 34094860, PMCID: PMC8164002, DOI: 10.1016/j.jot.2021.04.002.Peer-Reviewed Original ResearchTrabecular bone scoreBone mineral densityDual-energy X-ray absorptiometryLPV/rAntiretroviral therapyART initiationLower BMIBone scoreRisk factorsMineral densityBone microarchitectureBaseline TBSHuman immunodeficiency virus (HIV) infectionNormal bone mineral densityBone damageDifferent antiretroviral agentsHIV treatment historyImpaired bone microarchitectureLower baseline CD4Immunodeficiency virus infectionTraditional risk factorsClinicians additional informationX-ray absorptiometryKey risk factorsBaseline CD4Long-term trabecular bone score and bone mineral density changes in Chinese antiretroviral-treated HIV-infected individuals
Guan W, Pan W, Yu W, Cao W, Lin Q, Zhang Z, Song X, Li Y, Tian J, Xu Y, Li T, Hsieh E. Long-term trabecular bone score and bone mineral density changes in Chinese antiretroviral-treated HIV-infected individuals. Archives Of Osteoporosis 2021, 16: 41. PMID: 33624129, PMCID: PMC9675940, DOI: 10.1007/s11657-021-00890-0.Peer-Reviewed Original ResearchConceptsTrabecular bone scoreBone mineral densityTH bone mineral densityNormal bone mineral densityAntiretroviral therapyBone scoreART initiationFemoral neckMineral densityBone microarchitectureTotal hip (TH) BMDLumbar spine (LS) BMDBone mineral density changesFN bone mineral densityLarge tertiary care hospitalRetrospective chart reviewTertiary care hospitalMineral density changesMean percent decreaseResultsFour hundred fiftyPercent decreaseAdult PWHChart reviewCare hospitalBMD changes
2020
SUN-333 Burosumab Improves Bone Density in Patients with X-Linked Hypophosphatemia
Murari K, Insogna K. SUN-333 Burosumab Improves Bone Density in Patients with X-Linked Hypophosphatemia. Journal Of The Endocrine Society 2020, 4: sun-333. PMCID: PMC7207437, DOI: 10.1210/jendso/bvaa046.1470.Peer-Reviewed Original ResearchTrabecular bone scoreBone mineral densityL-spine bone mineral densityTotal hip bone mineral densityHip bone mineral densityBone scorePhase III clinical trialsRegional bone mineral densityRenal phosphate leakCourse of treatmentHuman monoclonal antibodyConsiderable clinical relevanceSignificant increaseFGF-23Frequent siteClinical trialsMineral densityMineral metabolismBone densityDrug treatmentPhosphate leakBurosumabBMD measurementsClinical relevanceStudy subjects
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