2021
Causes of medication non-adherence and the acceptability of support strategies for people with hypertension in Uganda: A qualitative study
Wilkinson R, Garden E, Nanyonga RC, Squires A, Nakaggwa F, Schwartz JI, Heller DJ. Causes of medication non-adherence and the acceptability of support strategies for people with hypertension in Uganda: A qualitative study. International Journal Of Nursing Studies 2021, 126: 104143. PMID: 34953374, DOI: 10.1016/j.ijnurstu.2021.104143.Peer-Reviewed Original ResearchConceptsCauses of medicationPoor medication adherenceNon-communicable diseasesHypertension controlMedication adherenceCommon non-communicable diseasesMedication side effectsLack of symptomsUrban private hospitalsMonthly group meetingsHealth Belief ModelTraditional herbal medicineHypertensive medicationsUntreated hypertensionAdherence clubsAdherence interventionsConventional content analysis approachText remindersSide effectsHypertensionPatientsMedicationsPatient effortHealthcare providersContext-specific barriers
2020
Early discontinuation of pharmacotherapy in U.S. veterans diagnosed with PTSD and the role of psychotherapy
Duek O, Pietrzak RH, Petrakis I, Hoff R, Harpaz-Rotem I. Early discontinuation of pharmacotherapy in U.S. veterans diagnosed with PTSD and the role of psychotherapy. Journal Of Psychiatric Research 2020, 132: 167-173. PMID: 33126010, DOI: 10.1016/j.jpsychires.2020.10.005.Peer-Reviewed Original ResearchConceptsPosttraumatic stress disorderRisk factorsEarly discontinuationMedication discontinuationPsychotropic medicationsPoor medication adherenceSimilar risk factorsStrong risk factorDeterminants of discontinuationKey risk factorsRole of psychotherapySingle medicationMedication adherenceMedication treatmentPsychiatric comorbidityAntipsychotic medicationPatient educationDiscontinuationOlder veteransMedicationsAdjunctive psychotherapyYounger veteransEarly interventionU.S. veteransVA treatmentT217. MEDICATION ADHERENCE AND ITS CORRELATES AMONG PATIENTS WITH RECURRENT SCHIZOPHRENIA: A LARGE-SCALE STUDY IN CHINA
Ross B, Wang D, Xi C, Pan Y, Zhou L, Yang X, Wu G, Ouyang X, Si T, Liu Z, Hu X. T217. MEDICATION ADHERENCE AND ITS CORRELATES AMONG PATIENTS WITH RECURRENT SCHIZOPHRENIA: A LARGE-SCALE STUDY IN CHINA. Schizophrenia Bulletin 2020, 46: s315-s315. PMCID: PMC7234590, DOI: 10.1093/schbul/sbaa029.777.Peer-Reviewed Original ResearchMedication Adherence Rating ScaleRecurrent schizophreniaMedication adherenceClinical characteristicsSchizophrenia patientsAcute periodAntipsychotic medicationGood adherenceClinical Global Impressions-SeverityOlder ageRating ScaleTotal scoreBetter medication adherenceDuration of illnessManagement of patientsNumber of relapsesPoor medication adherenceSeverity of illnessCGI-S scoresBivariate logistic regression modelSocio-demographic dataLogistic regression modelsMedication useClinical correlatesRisk factors
2019
Cardioprotective medication adherence among patients with coronary heart disease in China: a systematic review
Ni Z, Dardas L, Wu B, Shaw R. Cardioprotective medication adherence among patients with coronary heart disease in China: a systematic review. Heart Asia 2019, 11: e011173. PMID: 31297162, PMCID: PMC6590990, DOI: 10.1136/heartasia-2018-011173.Peer-Reviewed Original ResearchCoronary heart diseaseCardioprotective medication adherenceMedication adherenceSystematic reviewPoor adherenceHeart diseaseSociodemographic characteristicsMedication-related knowledgeSecondary prevention guidelinesSecondary prevention medicationsPatients' sociodemographic characteristicsPoor medication adherencePatient medication adherenceAllied Health LiteratureHigh mortality rateHealth educational programsCardioprotective medicationsMedication characteristicsPrevention medicationsPrevention guidelinesPatient's perspectivePhysician perspectivesCumulative IndexReminder cardsMortality rateCorrelates of Future Violence in People Being Treated for Schizophrenia
Buchanan A, Sint K, Swanson J, Rosenheck R. Correlates of Future Violence in People Being Treated for Schizophrenia. American Journal Of Psychiatry 2019, 176: 694-701. PMID: 31014102, DOI: 10.1176/appi.ajp.2019.18080909.Peer-Reviewed Original ResearchConceptsClinical Antipsychotic TrialsRecent violent victimizationStudy entryMedication adherenceMultivariable analysisMental Health Clinical Antipsychotic TrialsInjurious violenceMultivariable hazard ratiosPoor medication adherenceIntervention Effectiveness (CATIE) studyLongitudinal multivariable analysesProportional hazards modelChildhood risk factorsHazard ratioMedication nonadherenceClinical variablesRisk factorsTreatment strategiesAntipsychotic TrialsBaseline symptomsClinical conditionsLarge cohortHazards modelDrug useEffectiveness studies
2015
Association between depression and nonadherence to antiretroviral therapy in pregnant women with perinatally acquired HIV
Sheth SS, Coleman J, Cannon T, Milio L, Keller J, Anderson J, Argani C. Association between depression and nonadherence to antiretroviral therapy in pregnant women with perinatally acquired HIV. AIDS Care 2015, 27: 350-354. PMID: 25616659, DOI: 10.1080/09540121.2014.998610.Peer-Reviewed Original ResearchConceptsHistory of depressionHIV RNA levelsAntiretroviral therapyThird trimesterMedication adherencePregnant womenMean HIV RNA levelUndetectable HIV RNA levelsCharts of womenHIV infection characteristicsLifelong chronic illnessRNA levelsRetrospective cohort studyPoor medication adherenceUnique psychosocial challengesOptimal medication adherenceTreatment of depressionUnstable living situationsPregnant patientsCohort studyPreconception periodPregnancy outcomesART nonadherenceHIV treatmentPrenatal care
2012
Mobile Directly Observed Therapy: Monitoring and Improving Hydroxyurea Adherence in Pediatric Sickle Cell Patients
Creary S, Gladwin M, Krishnamurti L. Mobile Directly Observed Therapy: Monitoring and Improving Hydroxyurea Adherence in Pediatric Sickle Cell Patients. Blood 2012, 120: 2060. DOI: 10.1182/blood.v120.21.2060.2060.Peer-Reviewed Original ResearchSickle cell diseaseMedication possession ratioPediatric sickle cell diseaseLaboratory markersPediatric sickle cell patientsMorisky Medication Adherence ScaleAcute chest syndromeFrequent pain crisesHemoglobin F percentageHemoglobin SS diseasePrescription refill recordsMedication Adherence ScaleAnti-tuberculosis therapyPoor medication adherenceLarge clinical trialsRed blood cell disordersSelf-reported adherenceSickle cell patientsBlood cell disordersDOT participantsHU adherenceChest syndromePain crisisMedication ingestionPossession ratio
1997
Adherence in AIDS clinical trials: A framework for clinical research and clinical care
Ickovics J, Meisler A. Adherence in AIDS clinical trials: A framework for clinical research and clinical care. Journal Of Clinical Epidemiology 1997, 50: 385-391. PMID: 9179096, DOI: 10.1016/s0895-4356(97)00041-3.Peer-Reviewed Original ResearchConceptsClinical trialsAIDS clinical trialsPoor medication adherenceAssessment of adherencePatient-provider relationshipClinical trial dataProtease inhibitor drugsTreatment regimenMedication adherenceMedical adherencePatient participationClinical careDrug failureTherapeutic outcomesViral resistanceNew treatmentsPatient careTrial dataTherapeutic valueClinical settingClinical interventionsClinical researchInhibitor drugsTrialsGood adherence
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