2025
Alterations in lipid profiles in children with perinatally acquired HIV infection living in Ghana: A cross-sectional study
Ayanful-Torgby R, Shabanova V, Essuman A, Boafo E, Amoah L, Paintsil E. Alterations in lipid profiles in children with perinatally acquired HIV infection living in Ghana: A cross-sectional study. PLOS ONE 2025, 20: e0318314. PMID: 40674377, PMCID: PMC12270137, DOI: 10.1371/journal.pone.0318314.Peer-Reviewed Original ResearchConceptsPrevalence of dyslipidemiaAntiretroviral therapyLipid profileLDL-CTotal cholesterolCross-sectional studyDyslipidemia prevalenceLipoprotein cholesterolAbnormal LDL-C levelsMonitoring of lipid profileHormonal changesEarly onset cardiovascular diseaseCardiovascular diseaseLifelong antiretroviral therapyHigh-density lipoprotein cholesterolLow-density lipoprotein cholesterolLDL-C levelsElevated total cholesterolConfirmatory investigationsEffects of ageLipid profile levelsAge groupsLevels of TCAge group 6Children Aged 6Improving Cardiovascular Clinical Competencies for the Menopausal Transition A Focus on Cardiometabolic Health in Midlife
Dastmalchi L, Gulati M, Thurston R, Lau E, Sarma A, Marfori C, Gaffey A, Faubion S, Laddu D, Shufelt C, Sharma G. Improving Cardiovascular Clinical Competencies for the Menopausal Transition A Focus on Cardiometabolic Health in Midlife. JACC Advances 2025, 4: 101791. PMID: 40392169, PMCID: PMC12277619, DOI: 10.1016/j.jacadv.2025.101791.Peer-Reviewed Original ResearchWomen's cardiovascular healthCardiovascular healthCardiovascular diseaseMenopausal transitionCardiovascular disease risk scoreSystemic menopausal hormone therapyMental health changesCardiovascular disease riskMenopausal hormone therapyManagement of cardiovascular diseaseCardiometabolic healthHealth changesClinical competenceMedical trainingInfluence of chronological ageHormone therapyPostgraduate curriculaRisk scoreScreening toolVasomotor symptomsOvarian agingHealthSleep problemsHormonal changesLongitudinal studyPerformance of algorithms using wrist temperature for retrospective ovulation day estimate and next menses start day prediction: a prospective cohort study
Wang Y, Park J, Zhang C, Jukic A, Baird D, Coull B, Hauser R, Mahalingaiah S, Zhang S, Curry C. Performance of algorithms using wrist temperature for retrospective ovulation day estimate and next menses start day prediction: a prospective cohort study. Human Reproduction 2025, 40: 469-478. PMID: 39881571, PMCID: PMC11879225, DOI: 10.1093/humrep/deaf005.Peer-Reviewed Original ResearchConceptsNext mensesDay of ovulationProspective cohort studyMenstrual cycleBasal body temperatureLH testCohort studyCycle lengthWomen's Health StudyROLE OF CHANCEDaily basal body temperatureAssociated with ovulationFUNDING/COMPETING INTEREST(SWider implicationsMensesWrist temperatureMenstruating femalesHormonal changesOvulation day
2023
Inherited and Acquired Thrombophilias
Abhari P, Paidas M. Inherited and Acquired Thrombophilias. 2023, 114-122. DOI: 10.1002/9781119636540.ch14.Peer-Reviewed Original ResearchThrombophilic conditionsTransient hypercoagulable stateCoagulation factor levelsContext of pregnancyAcquired ThrombophiliaAntifibrinolytic systemsNeonatal outcomesProthrombotic tendencyHypercoagulable stateHormonal changesClinical consequencesThrombotic conditionsFactor levelsPregnancyThrombophiliaMaternalDiagnosis
2021
Impact of Sex on Sleep Disorders Across the Lifespan
Tobias L, Thapa S, Won CHJ. Impact of Sex on Sleep Disorders Across the Lifespan. Clinics In Chest Medicine 2021, 42: 427-442. PMID: 34353449, DOI: 10.1016/j.ccm.2021.04.005.ChaptersConceptsSleep disordersAdverse maternal outcomesSleep-disordered breathingQuality of lifeImpact of sexDevelopment of insomniaMaternal outcomesMedical comorbiditiesSex predominanceVasomotor symptomsSleep symptomsReproductive milestonesSleep disturbancesSleep architectureSleep disruptionHormonal changesWomen's livesDisordersMenopausePregnancySymptomsComorbiditiesDerangementInsomniaPrevalenceChapter 48 Malignancies in systemic lupus erythematosus
Ladouceur A, Tissera H, Clarke A, Ramsey-Goldman R, Gordon C, Hansen J, Bernatsky S. Chapter 48 Malignancies in systemic lupus erythematosus. 2021, 461-467. DOI: 10.1016/b978-0-12-814551-7.00048-9.ChaptersSystemic lupus erythematosusSLE patientsLupus erythematosusGeneral populationOverall cancer incidence ratesHormone-sensitive cancersCancer incidence ratesRisk of breastDrug exposureIncidence rateProstate cancerHormonal changesHigh riskCancer profilePatientsCancerGenetic factorsErythematosusRiskPotential reasonsLymphomaMalignancyPathophysiologyPopulationBreast
2020
Thromboembolism
Paidas M. Thromboembolism. 2020, 181-200. DOI: 10.1002/9781119635307.ch19.Peer-Reviewed Original ResearchDeep venous thrombosisVenous thromboembolismRisk of DVTRisk of VTETransient hypercoagulable stateLeft lower extremityPrimary diagnostic modalitySystemic coagulationThromboembolic eventsNonpregnant womenFetal risksHypercoagulable stateVenous thrombosisVenous ultrasoundHemostatic challengesPregnant womenVascular traumaRisk factorsLower extremitiesVascular stasisDiagnostic modalitiesHormonal changesColor DopplerFibrinolytic systemPregnancyChanges in excessive alcohol use among older women across the menopausal transition: a longitudinal analysis of the Study of Women’s Health Across the Nation
Peltier MR, Verplaetse TL, Roberts W, Moore K, Burke C, Marotta PL, Phillips S, Smith PH, McKee SA. Changes in excessive alcohol use among older women across the menopausal transition: a longitudinal analysis of the Study of Women’s Health Across the Nation. Biology Of Sex Differences 2020, 11: 37. PMID: 32665024, PMCID: PMC7362573, DOI: 10.1186/s13293-020-00314-7.Peer-Reviewed Original ResearchConceptsMenopausal transitionExcessive alcohol useExcessive drinkingAlcohol useRandom effects logistic regressionAlcohol-related health consequencesSuch health problemsMethodsThe present studyPresent studyConclusionsThe present studyMenopausal transition stageSex-specific factorsHigher testosterone levelsBackgroundRecent dataEstradiol levelsPostmenopausal stageSex hormonesTestosterone levelsHormonal changesOlder womenAlcoholism criteriaAlcohol abuseAlcohol consumptionWomen's healthStudy of womenSlc20a1/Pit1 and Slc20a2/Pit2 are essential for normal skeletal myofiber function and survival
Chande S, Caballero D, Ho BB, Fetene J, Serna J, Pesta D, Nasiri A, Jurczak M, Chavkin NW, Hernando N, Giachelli CM, Wagner CA, Zeiss C, Shulman GI, Bergwitz C. Slc20a1/Pit1 and Slc20a2/Pit2 are essential for normal skeletal myofiber function and survival. Scientific Reports 2020, 10: 3069. PMID: 32080237, PMCID: PMC7033257, DOI: 10.1038/s41598-020-59430-4.Peer-Reviewed Original ResearchConceptsHyp miceMuscle functionSkeletal muscleMyofiber functionNormal body weightSkeletal muscle atrophyGene dose-dependent reductionConditional knockout miceReduced oxygen consumption rateStimulation of AMP kinaseKnockout miceHypophosphatemic disordersMuscle atrophyERK1/2 activationGrip strengthConditional deletionHormonal changesLow bloodBody weightC2C12 myoblastsMiceFurther evaluationBlood phosphateDependent reductionAMP kinase
2019
Towards precision medicine for stress disorders: diagnostic biomarkers and targeted drugs
Le-Niculescu H, Roseberry K, Levey D, Rogers J, Kosary K, Prabha S, Jones T, Judd S, McCormick M, Wessel A, Williams A, Phalen P, Mamdani F, Sequeira A, Kurian S, Niculescu A. Towards precision medicine for stress disorders: diagnostic biomarkers and targeted drugs. Molecular Psychiatry 2019, 25: 918-938. PMID: 30862937, PMCID: PMC7192849, DOI: 10.1038/s41380-019-0370-z.Peer-Reviewed Original ResearchMeSH KeywordsAdaptor Proteins, Signal TransducingAdultbeta 2-MicroglobulinBiomarkersDEAD-box RNA HelicasesFemaleGene ExpressionHumansMaleMental DisordersMiddle AgedMolecular Targeted TherapyNogo ProteinsPrecision MedicinePredictive Value of TestsProto-Oncogene ProteinsReceptors, ImmunologicStress, PsychologicalTacrolimus Binding ProteinsTelomere HomeostasisConceptsPredictive biomarkersGene expression biomarkersTelomere lengthBlood gene expression biomarkersPossible new drug candidateStress disorderPsychological stressFuture psychiatric hospitalizationsVisual analog scaleHigh-risk groupSimple visual analog scaleDrug repurposing analysisExpression biomarkersGene expression signaturesAnalog scaleAdverse outcomesCalcium folinateCohort designHormonal changesPsychiatric hospitalizationDecreased qualityBiomarker findingsPsychiatric disordersPsychiatric patientsPatient stratification
2018
Sleep in Women Across the Life Span
Pengo M, Won C, Bourjeily G. Sleep in Women Across the Life Span. CHEST Journal 2018, 154: 196-206. PMID: 29679598, PMCID: PMC6045782, DOI: 10.1016/j.chest.2018.04.005.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsSleep disturbancesSleep disordersSleep deprivationRestless legs syndromePoor sleep qualityParticular health outcomesLegs syndromeSex hormonesSleep changesNeonatal lifePoor sleepHormonal changesSleep qualitySleep pathologyHealth outcomesSleep regulationSleep conditionsFemale subjectsSleep challengesUnderstanding of sleepSleepWomenMenopauseDisordersOutcomesNeonatal Hormone Concentrations and Risk of Testicular Germ Cell Tumors (TGCT)
Morimoto LM, Zava D, McGlynn KA, Stanczyk FZ, Kang AY, Ma X, Wiemels JL, Metayer C. Neonatal Hormone Concentrations and Risk of Testicular Germ Cell Tumors (TGCT). Cancer Epidemiology Biomarkers & Prevention 2018, 27: 488-495. PMID: 29475970, PMCID: PMC5884718, DOI: 10.1158/1055-9965.epi-17-0879.Peer-Reviewed Original ResearchConceptsHormone levelsTGCT riskTesticular germ cell tumor incidencePopulation-based case-control studyNon-Hispanic white subjectsAbrupt hormonal changesTumor histologic subtypeCase-control studySex steroid hormonesEarly fetal developmentLogistic regression modelsNeonatal androgensHistologic subtypeNeonatal periodTumor incidenceAndrogen levelsHormone imbalanceHormonal changesFetal developmentAge groupsWhite subjectsSteroid hormonesBlood spotsLiquid chromatography-tandem mass spectrometryTGCT
2016
Rates and determinants of incidence and clearance of cervical HPV genotypes among HIV-seropositive women in Pune, India
Mane A, Sahasrabuddhe VV, Nirmalkar A, Risbud AR, Sahay S, Bhosale RA, Vermund SH, Mehendale SM. Rates and determinants of incidence and clearance of cervical HPV genotypes among HIV-seropositive women in Pune, India. Journal Of Clinical Virology 2016, 88: 26-32. PMID: 28152432, PMCID: PMC5441893, DOI: 10.1016/j.jcv.2016.10.013.Peer-Reviewed Original ResearchConceptsHIV-seropositive womenCervical HPV genotypesHPV genotypesClearance rateHPV infectionAge-related hormonal changesRoche Linear Array HPVAlpha-7 speciesAntiretroviral therapy statusCarcinogenic HPV genotypesCervical HPV infectionGenotype-specific prevalenceLinear Array HPVAge of participantsCD4 countHPV incidenceImmunologic factorsDeterminants of incidenceHPV typesTherapy statusProspective studyCervical samplesIncidence rateHormonal changesEtiologic studiesChapter 46 Malignancies in Systemic Lupus Erythematosus
Tissera H, Clarke A, Goldman R, Gordon C, Hansen J, Bernatsky S. Chapter 46 Malignancies in Systemic Lupus Erythematosus. 2016, 411-415. DOI: 10.1016/b978-0-12-801917-7.00046-2.ChaptersSystemic lupus erythematosusSLE patientsGeneral populationLupus erythematosusOverall cancer incidence ratesHormone-sensitive cancersCancer incidence ratesRisk of breastDrug exposureIncidence rateProstate cancerHormonal changesHigh riskCancer profilePatientsCancerGenetic factorsErythematosusRiskPopulationPotential reasonsLymphomaMalignancyPathophysiologyBreast
2015
Associations between Parity, Hair Hormone Profiles during Pregnancy and Lactation, and Infant Development in Rhesus Monkeys (Macaca mulatta)
Dettmer AM, Rosenberg KL, Suomi SJ, Meyer JS, Novak MA. Associations between Parity, Hair Hormone Profiles during Pregnancy and Lactation, and Infant Development in Rhesus Monkeys (Macaca mulatta). PLOS ONE 2015, 10: e0131692. PMID: 26172048, PMCID: PMC4501543, DOI: 10.1371/journal.pone.0131692.Peer-Reviewed Original ResearchConceptsInfant developmentHormonal profileNeurobehavioral developmentRhesus monkeysFirst monthInfant neurobehavioral developmentEarly postnatal periodStage of pregnancyFemale rhesus monkeysPregnancy/lactationInfluence of parityPoor developmental outcomesNon-human primatesReflex scoresMaternal cortisolInfant exposureHormonal changesSensorimotor scoresPostnatal periodHormone profilesHormone concentrationsPrimiparous mothersPregnancyHormone productionEndocrine activity
2014
Intrauterine devices and endometrial cancer risk: A pooled analysis of the Epidemiology of Endometrial Cancer Consortium
Felix AS, Gaudet MM, La Vecchia C, Nagle CM, Shu XO, Weiderpass E, Adami HO, Beresford S, Bernstein L, Chen C, Cook LS, De Vivo I, Doherty JA, Friedenreich CM, Gapstur SM, Hill D, Horn‐Ross P, Lacey JV, Levi F, Liang X, Lu L, Magliocco A, McCann SE, Negri E, Olson SH, Palmer JR, Patel AV, Petruzella S, Prescott J, Risch HA, Rosenberg L, Sherman ME, Spurdle AB, Webb PM, Wise LA, Xiang Y, Xu W, Yang HP, Yu H, Zeleniuch‐Jacquotte A, Brinton LA. Intrauterine devices and endometrial cancer risk: A pooled analysis of the Epidemiology of Endometrial Cancer Consortium. International Journal Of Cancer 2014, 136: e410-e422. PMID: 25242594, PMCID: PMC4267918, DOI: 10.1002/ijc.29229.Peer-Reviewed Original ResearchConceptsEndometrial Cancer ConsortiumEndometrial cancer riskIntrauterine deviceEC riskPooled analysisCancer riskLast useCancer ConsortiumOlder ageUse of IUDsMultivariable logistic regressionConfidence intervalsPooled odds ratioCase-control studyInert intrauterine deviceDuration of useHeavy bleedingOdds ratioReversible contraceptivesHormonal changesEC casesReduced riskBiologic effectsUterine environmentLogistic regressionHormonal Changes During Menopause and the Impact on Fluid Regulation
Stachenfeld NS. Hormonal Changes During Menopause and the Impact on Fluid Regulation. Reproductive Sciences 2014, 21: 555-561. PMID: 24492487, PMCID: PMC3984489, DOI: 10.1177/1933719113518992.Peer-Reviewed Original ResearchConceptsHormone therapySodium retentionMenopausal womenFluid regulationCardiovascular functionAldosterone-mediated sodium retentionRisk of hyponatremiaBlood pressure responseFemale reproductive hormonesFluid-regulating hormonesBody fluid volumeRisk of dehydrationBody fluid regulationEstrogen therapyHypervolemic hyponatremiaCardiovascular riskEstradiol effectsSodium loadProgesterone exposureMineralocorticoid receptorProgestogen exposureReproductive hormonesReproductive surgeryHormonal changesDistal tubules
2008
Breast Pain
Golshan M. Breast Pain. 2008, 345-346. DOI: 10.1007/978-0-387-75246-4_85.Peer-Reviewed Original ResearchBreast painFourth of womenOvarian estrogen productionBreast nodularityBreast symptomsHormonal milieuEstrogen productionCommon complaintPalpable abnormalityProgesterone secretionBreast cancerHormonal changesPainPatientsNodularityCommon typeMensesCancerBreastWomenHyperprolactinemiaCommon patternSymptomsMenstruationAbnormalities
2004
Puberty, Ovarian Steroids, and Stress
YOUNG E, ALTEMUS M. Puberty, Ovarian Steroids, and Stress. Annals Of The New York Academy Of Sciences 2004, 1021: 124-133. PMID: 15251881, DOI: 10.1196/annals.1308.013.Peer-Reviewed Original ResearchConceptsStressful life eventsMajor depressionDepressed womenPostmenopausal depressed womenReproductive hormonal changesLife eventsNormal progesteronePremenopausal womenCommon etiologyOvarian hormonesOvarian steroidsHPA axisAdrenal axisNormal womenLow estradiolFirst episodeDepressed menHormonal changesBaseline cortisolEstradiolInhibitory feedbackPubertyYoung adulthoodWomenDepression
2003
Spontaneous Coronary Artery Dissection in a Woman Receiving 5-Fluorouracil
Abbott JD, Curtis JP, Murad K, Kramer HM, Remetz MS, Setaro JF, Brennan JJ. Spontaneous Coronary Artery Dissection in a Woman Receiving 5-Fluorouracil. Angiology 2003, 54: 721-724. PMID: 14666962, DOI: 10.1177/000331970305400613.Peer-Reviewed Case Reports and Technical NotesConceptsSpontaneous coronary artery dissectionCoronary artery dissectionArtery dissectionMyocardial infarctionAcute ST-elevation myocardial infarctionST-elevation myocardial infarctionLeft anterior descending (LAD) arteryExtensive coronary dissectionAnterior descending (LAD) arteryPelvic radiation therapyCoronary dissectionPelvic radiationCoronary angiographyIntractable vomitingThrombolytic therapyCervical cancerHormonal changesRadiation therapyHemodynamic stressDissectionVomitingTherapyWomenVasospasmStenting
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply