2008
Support for the hypothesis that successful immunotherapy of various cancers can be achieved by inhibiting a progesterone associated immunomodulatory protein
Check J, Dix E, Sansoucie L. Support for the hypothesis that successful immunotherapy of various cancers can be achieved by inhibiting a progesterone associated immunomodulatory protein. Medical Hypotheses 2008, 72: 87-90. PMID: 18842348, DOI: 10.1016/j.mehy.2008.05.042.Peer-Reviewed Original ResearchConceptsPIBF proteinCancer cellsProgesterone secretionLeukemia cell linesProgesterone receptor antagonist mifepristoneImmunomodulatory proteinsQuality of lifeCell linesAnecdotal improvementMifepristone therapySuccessful immunotherapyAntagonist mifepristoneNormal pregnancyNormal body functionType therapyProgesterone receptorImmune surveillanceHuman leukemia cell linesMetastatic human cancersSpontaneous cancersProgesteroneCancerBody functionsTherapyProtein expressionBreast Pain
Golshan M. Breast Pain. 2008, 345-346. DOI: 10.1007/978-0-387-75246-4_85.Peer-Reviewed Original ResearchBreast painFourth of womenOvarian estrogen productionBreast nodularityBreast symptomsHormonal milieuEstrogen productionCommon complaintPalpable abnormalityProgesterone secretionBreast cancerHormonal changesPainPatientsNodularityCommon typeMensesCancerBreastWomenHyperprolactinemiaCommon patternSymptomsMenstruationAbnormalities
2007
Pulsatile Luteinizing Hormone Amplitude and Progesterone Metabolite Excretion Are Reduced in Obese Women
Jain A, Polotsky A, Rochester D, Berga S, Loucks T, Zeitlian G, Gibbs K, Polotsky H, Feng S, Isaac B, Santoro N. Pulsatile Luteinizing Hormone Amplitude and Progesterone Metabolite Excretion Are Reduced in Obese Women. The Journal Of Clinical Endocrinology & Metabolism 2007, 92: 2468-2473. PMID: 17440019, DOI: 10.1210/jc.2006-2274.Peer-Reviewed Original ResearchConceptsNormal-weight womenDaily hormonesObese womenLH pulsationsPregnanediol glucuronideOvarian axis functionAbnormal menstrual cyclesLH pulse frequencyBody mass indexNormal-weight controlsProgesterone metabolite excretionSeparate control groupEumenorrheic womenLH pulsesMass indexAxis functionFemale obesityMenstrual cycleObese stateProgesterone secretionProgesterone metabolitesUrine collectionMetabolite excretionFirst morningControl groupReduced placental growth and hCG secretion in vitro induced by antiphospholipid antibodies but not by anti-Ro or anti-La: studies on sera from women with SLE/PAPS
Schwartz N, Shoenfeld Y, Barzilai O, Cervera R, Font J, Blank M, Yacobi S, Patlas N, Cohen A, Mevorach D, Ornoy A. Reduced placental growth and hCG secretion in vitro induced by antiphospholipid antibodies but not by anti-Ro or anti-La: studies on sera from women with SLE/PAPS. Lupus 2007, 16: 110-120. PMID: 17402367, DOI: 10.1177/0961203306075741.Peer-Reviewed Original ResearchConceptsPrimary anti-phospholipid syndromeAnti-phospholipid antibodiesRecurrent pregnancy lossSystemic lupus erythematosusPlacental damagePregnancy lossBetahCG levelsPlacental growthAnti-phospholipid syndromeHuman placental explantsAnti-La antibodiesDifferent antibodiesAnti-RoAntiphospholipid antibodiesThromboembolic eventsLupus erythematosusAutoimmune diseasesPlacental explantsPredictive markerProgesterone secretionHCG secretionSensitive markerHigh titersTrophoblastic apoptosisAntibodies
1987
Differentiaton of Human Cytotrophoblast into Syncytiotrophoblast in Culture
Kliman H, Feinman M, Strauss J. Differentiaton of Human Cytotrophoblast into Syncytiotrophoblast in Culture. Trophoblast Research 1987, 407-421. DOI: 10.1007/978-1-4757-1936-9_29.Peer-Reviewed Original ResearchHuman chorionic gonadotropinHuman placental lactogenPrevention of rejectionPatterns of hCGHuman term placentaFetal circulationMononuclear cellsProgesterone secretionChorionic gonadotropinPlacental lactogenTerm placentaHuman cytotrophoblastsImmunoglobulin transportTrophoblastImmunocytochemical localizationProtein hormonesSyncytiotrophoblastCytotrophoblastsFetusesMothersEarlier reportsMorphological changesReportSyncytial structureCells
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