2025
A randomized controlled trial to assess whether a telehealth-based contingency management intervention reduces alcohol use for individuals with alcohol use disorder
Jett J, Tyutyunnyk D, Beck R, Palmer K, Ryan D, Sanchez J, Weeks D, McPherson S, Chaytor N, Kiluk B, Javors M, Ginsburg B, Murphy S, Hill-Kapturczak N, McDonell M. A randomized controlled trial to assess whether a telehealth-based contingency management intervention reduces alcohol use for individuals with alcohol use disorder. Contemporary Clinical Trials 2025, 150: 107807. PMID: 39824379, DOI: 10.1016/j.cct.2025.107807.Peer-Reviewed Original ResearchConceptsAlcohol use disorderContingency managementAlcohol useUse disorderPredictors of intervention outcomeOnline cognitive behavioral therapyCognitive behavioral therapyContingency management interventionAlcohol-related outcomesDecreased alcohol useReducing alcohol useReward contingenciesBehavioral therapyImpact of CMConfirm abstinencePEth resultsCM interventionIntervention outcomesExcessive drinkingCBT4CBTAbstinenceIn-personRewardFollow-upAlcohol
2020
Changes in excessive alcohol use among older women across the menopausal transition: a longitudinal analysis of the Study of Women’s Health Across the Nation
Peltier MR, Verplaetse TL, Roberts W, Moore K, Burke C, Marotta PL, Phillips S, Smith PH, McKee SA. Changes in excessive alcohol use among older women across the menopausal transition: a longitudinal analysis of the Study of Women’s Health Across the Nation. Biology Of Sex Differences 2020, 11: 37. PMID: 32665024, PMCID: PMC7362573, DOI: 10.1186/s13293-020-00314-7.Peer-Reviewed Original ResearchConceptsMenopausal transitionExcessive alcohol useExcessive drinkingAlcohol useRandom effects logistic regressionAlcohol-related health consequencesSuch health problemsMethodsThe present studyPresent studyConclusionsThe present studyMenopausal transition stageSex-specific factorsHigher testosterone levelsBackgroundRecent dataEstradiol levelsPostmenopausal stageSex hormonesTestosterone levelsHormonal changesOlder womenAlcoholism criteriaAlcohol abuseAlcohol consumptionWomen's healthStudy of womenPain and reward circuits antagonistically modulate alcohol expectancy to regulate drinking
Le TM, Zhornitsky S, Zhang S, Li CR. Pain and reward circuits antagonistically modulate alcohol expectancy to regulate drinking. Translational Psychiatry 2020, 10: 220. PMID: 32636394, PMCID: PMC7341762, DOI: 10.1038/s41398-020-00909-z.Peer-Reviewed Original ResearchConceptsMedial orbitofrontal cortexPath modelCue exposure taskWhole-brain regressionAlcohol cue exposurePAG connectivityPotential aversive effectsExposure tasksCue exposureAlcohol expectanciesSocial pleasureDrinking severityOrbitofrontal cortexFMRI dataConnectivity strengthPrecentral gyrusOccipital cortexPSP scoresAlcohol useAversive effectsExcessive drinkingNegative associationExpectancyPleasureCortexDrinking and responses to antidrinking messages among young adults: An fMRI study
Garrison KA, DeMartini KS, Corlett PR, Worhunsky PD, Krystal JH, O'Malley SS. Drinking and responses to antidrinking messages among young adults: An fMRI study. Addiction Biology 2020, 26: e12882. PMID: 32068323, PMCID: PMC7431375, DOI: 10.1111/adb.12882.Peer-Reviewed Original ResearchConceptsDrinking cuesNeural responsesYoung adultsFunctional magnetic resonanceSelf-reported drinkingPast monthNeutral cuesDrug cuesSmoking cuesHabitual responsesReward processingFMRI studyDrinking quantityCuesDependent individualsSubstance useAlcohol useBinge drinkingNegative consequencesGreater baselinePublic health campaignsExcessive drinkingHeavy drinkingHealth campaignsDrinking
2018
Trajectories of alcohol consumption in U.S. military veterans: Results from the National Health and Resilience in Veterans Study
Fuehrlein BS, Kachadourian LK, DeVylder EK, Trevisan LA, Potenza MN, Krystal JH, Southwick SM, Pietrzak RH. Trajectories of alcohol consumption in U.S. military veterans: Results from the National Health and Resilience in Veterans Study. American Journal On Addictions 2018, 27: 383-390. PMID: 29667712, DOI: 10.1111/ajad.12731.Peer-Reviewed Original ResearchMajor depressive disorderLifetime major depressive disorderAlcohol consumptionPredominant trajectoriesNational HealthVeterans StudyAlcohol Use Disorders Identification Test-ConsumptionBrief alcohol screensExcessive drinkingPopulation-based preventionSocial supportExcessive alcohol consumptionAlcohol use disorderLow social supportU.S. military veteransAlcohol screenBaseline determinantsDepressive disorderLatent growth mixture modelingMedical conditionsModerate drinkersRare drinkersModerate drinkingUse disordersGreater social support
2016
Roles of defective ALDH2 polymorphism on liver protection and cancer development
Matsumoto A, Thompson DC, Chen Y, Kitagawa K, Vasiliou V. Roles of defective ALDH2 polymorphism on liver protection and cancer development. Environmental Health And Preventive Medicine 2016, 21: 395-402. PMID: 27714678, PMCID: PMC5112207, DOI: 10.1007/s12199-016-0579-2.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsSerum transaminasesLiver protectionSerum alanine aminotransferase levelsExcessive drinkingAlanine aminotransferase levelsAlcohol-related cancersUseful biological markerAldehyde dehydrogenase 2 geneAminotransferase levelsLiver injuryAlcohol intakeAlcohol dosePotential cancer riskCancer riskALDH2 polymorphismEthanol loadHealthy individualsBiological markersCancer developmentMultiple studiesFurther studiesALDH2TransaminaseDrinkingRisk
2014
Alcohol expectancies and evaluations of aggression in alcohol-related intimate-partner verbal and physical aggression.
Kachadourian LK, Quigley BM, Leonard KE. Alcohol expectancies and evaluations of aggression in alcohol-related intimate-partner verbal and physical aggression. Journal Of Studies On Alcohol And Drugs 2014, 75: 744-52. PMID: 25208191, PMCID: PMC4161694, DOI: 10.15288/jsad.2014.75.744.Peer-Reviewed Original ResearchConceptsAlcohol-aggression expectanciesAggression expectanciesPhysical aggressionAlcohol expectanciesVerbal aggressionExcessive drinkingAlcohol-related aggressionEvaluations of aggressionAlcohol-related behaviorsSuch behaviorSuch aggressionAggressionStudy crossAggressive behaviorPrevious researchDrinking indicatorsIntimate partner violenceDrinkingExpectancyNf1 Regulates Alcohol Dependence-Associated Excessive Drinking and Gamma-Aminobutyric Acid Release in the Central Amygdala in Mice and Is Associated with Alcohol Dependence in Humans
Repunte-Canonigo V, Herman MA, Kawamura T, Kranzler HR, Sherva R, Gelernter J, Farrer LA, Roberto M, Sanna PP. Nf1 Regulates Alcohol Dependence-Associated Excessive Drinking and Gamma-Aminobutyric Acid Release in the Central Amygdala in Mice and Is Associated with Alcohol Dependence in Humans. Biological Psychiatry 2014, 77: 870-879. PMID: 25483400, PMCID: PMC4428692, DOI: 10.1016/j.biopsych.2014.07.031.Peer-Reviewed Original ResearchConceptsChronic intermittent ethanol vapor exposureGABA releaseWild-type miceGamma-aminobutyric acidAlcohol dependenceCentral amygdalaGamma-aminobutyric acid releaseIntermittent ethanol vapor exposureExcessive drinkingMouse central amygdalaEthanol vapor exposureHeterozygous null miceAlcohol dependence riskInduction of dependenceAlcohol drinkingAlcohol-related behaviorsDependent drinkingBinge drinkingTranslational investigationsNull miceCentral nucleusType 1 geneMiceAmygdalaAcid release
2011
Medications for unhealthy alcohol use: across the spectrum.
O'Malley SS, O'Connor PG. Medications for unhealthy alcohol use: across the spectrum. Alcohol Research 2011, 33: 300-12. PMID: 23580015, PMCID: PMC3860540.Peer-Reviewed Original ResearchConceptsUnhealthy alcohol useSpecialty careCare settingsAlcohol useAdvent of pharmacotherapyPrimary care providersPrimary care settingSpectrum of careHealth care settingsPrimary careCare providersHazardous drinkersEarly interventionExcessive drinkingCareAlcohol problemsTreatmentMedicationsPharmacotherapyPatientsCliniciansPrevalenceSettingDrinkers
2010
Compulsions
Tolin D. Compulsions. 2010, 1-3. DOI: 10.1002/9780470479216.corpsy0210.Peer-Reviewed Original Research
2001
Do drivers drink more when they use a safe ride?
Harding W, Caudill B, Moore B, Frissell K. Do drivers drink more when they use a safe ride? Journal Of Substance Abuse 2001, 13: 283-290. PMID: 11693452, DOI: 10.1016/s0899-3289(01)00085-2.Peer-Reviewed Original Research
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