2025
Three-year lifestyle changes, genetic risk, and risk of frailty among older adults: A national community-based cohort study
Zhong W, Wang X, Song W, Chen H, Xie J, Yan H, Wang J, Lv Y, Li Z, Shi X, Mao C. Three-year lifestyle changes, genetic risk, and risk of frailty among older adults: A national community-based cohort study. Clinical Nutrition 2025, 50: 29-37. PMID: 40367593, DOI: 10.1016/j.clnu.2025.04.033.Peer-Reviewed Original ResearchConceptsRisk of frailtyGenetic riskHealthy lifestyleUnhealthy lifestyleOlder adultsFrailty riskLate-lifeLifestyle changesChinese Longitudinal Healthy Longevity SurveyCommunity-based cohort studyHazard ratioPolygenic risk scoresGenetic risk groupsModerate-to-moderatelyCox proportional hazards regression modelsProportional hazards regression modelsLifestyle scoreHazards regression modelsLongevity SurveyHigh frailty riskPrevent frailtyLifestyle factorsFrailty indexCohort studyLifestyle combinationThe impact of social stress and healthy lifestyle on the mortality of Chinese older adults: a prospective cohort study (Preprint)
Yang J, Huang J, Huang Q, Gao J, Liu D, Li Z, Lv Y, Shi X, Mao C. The impact of social stress and healthy lifestyle on the mortality of Chinese older adults: a prospective cohort study (Preprint). JMIR Aging 2025 DOI: 10.2196/75942.Peer-Reviewed Original ResearchIntegrated healthy lifestyle even in late-life mitigates cognitive decline risk across varied genetic susceptibility
Wang J, Chen C, Zhou J, Xu Z, Xu L, Li X, Zhong Z, Lv Y, Shi X. Integrated healthy lifestyle even in late-life mitigates cognitive decline risk across varied genetic susceptibility. Nature Communications 2025, 16: 539. PMID: 39789005, PMCID: PMC11718162, DOI: 10.1038/s41467-024-55763-0.Peer-Reviewed Original ResearchConceptsFavorable lifestyleRate of cognitive declineGenetic riskCognitive declineUnfavorable lifestyleHealthy lifestyleAssociations of combined lifestyle factorsChinese Longitudinal Healthy Longevity SurveyCombined lifestyle factorsHigh genetic riskDimensions of cognitionCognitive decline riskAccelerated cognitive declineLongevity SurveyLifestyle factorsCognitive domainsLate-lifeOlder adultsCognitive functionDeclining riskLifestyleGenetic susceptibilityGenetic factorsRiskCognition
2024
Health-Related Behaviors and Risk of Common Age-Related Brain Diseases Across Severities of Genetic Risk
Marini S, Kimball T, Mayerhofer E, Tack R, Senff J, Prapiadou S, Rivier C, Duskin J, Kourkoulis C, Falcone G, Yechoor N, Tanzi R, Rosand J, Singh S, Parodi L, Anderson C. Health-Related Behaviors and Risk of Common Age-Related Brain Diseases Across Severities of Genetic Risk. Neurology 2024, 103: e210014. PMID: 39504504, DOI: 10.1212/wnl.0000000000210014.Peer-Reviewed Original ResearchConceptsLate-life depressionGenetic riskDementia riskUK Biobank (UKBEffects of healthy lifestylesHealth-related behaviorsGenetic predispositionElevated genetic riskProspective cohort studyHazard of strokeCox proportional hazards modelsAge-related brain diseasesLifestyle behaviorsCare scoresUKB participantsProportional hazards modelHealthy lifestyleIncidence of strokeMultivariate Cox proportional hazards modelPolygenic scoresTargeted interventionsLifestyle adjustmentsAggregate risk estimatesRisk estimatesCohort studyDigital Gaming and Exercise Among Youth With Type 1 Diabetes: Cross-Sectional Analysis of Data From the Type 1 Diabetes Exercise Initiative Pediatric Study
Patton S, Gal R, Bergford S, Calhoun P, Clements M, Sherr J, Riddell M. Digital Gaming and Exercise Among Youth With Type 1 Diabetes: Cross-Sectional Analysis of Data From the Type 1 Diabetes Exercise Initiative Pediatric Study. JMIR Pediatrics And Parenting 2024, 7: e57198. PMID: 38889077, PMCID: PMC11186795, DOI: 10.2196/57198.Peer-Reviewed Original ResearchExercise sessionsPhysical activityMinutes of physical activityLevels of physical activityRegular physical activityType 1 diabetesCross-sectional analysisDigital gamesHealthy lifestyleActive wearablesGame sessionsExerciseInsulin useNondigital gamesDaily activitiesPediatric studiesSessionsContext of youthDisease statusYouthT1DCharacteristics of digital gamesInsulin pumpObservation periodContinuous glucose monitoringHealthy Lifestyle and the Likelihood of Becoming a Centenarian
Li Y, Wang K, Jigeer G, Jensen G, Tucker K, Lv Y, Shi X, Gao X. Healthy Lifestyle and the Likelihood of Becoming a Centenarian. JAMA Network Open 2024, 7: e2417931. PMID: 38900423, PMCID: PMC11190803, DOI: 10.1001/jamanetworkopen.2024.17931.Peer-Reviewed Original ResearchConceptsHealthy lifestyleCase-control studyLifestyle factorsOlder adultsChinese Longitudinal Healthy Longevity SurveySelf-reported chronic conditionsHealthy lifestyle scoreImprove lifestyle behaviorsChinese older adultsAssociated with life expectancyProspective nested case-control studyNested Case-Control StudyLifestyle scoreLifestyle behaviorsLongevity SurveyOlder age groupsHealth outcomesChronic conditionsSociodemographic characteristicsCommunity-BasedMental wellnessYear of entryMain OutcomesOdds ratioMiddle-agedExtended Reality and Older Adult Mental Health: A Systematic Review of the Field and Current Applications
Dickinson R, Fahed M, Sekhon H, Faruque S, Kimball J, Gupta S, Handa I, Alkhatib F, Singh A, Vahia I. Extended Reality and Older Adult Mental Health: A Systematic Review of the Field and Current Applications. American Journal Of Geriatric Psychiatry 2024, 32: s130. DOI: 10.1016/j.jagp.2024.01.219.Peer-Reviewed Original ResearchOlder adult populationOlder adultsFall riskMental healthAdult populationCare of older adultsFall risk assessmentAdult mental healthEvidence-based applicationsPhysical activitySystematic literature searchCommon barriersHealthcare providersHealthy lifestylePhysical healthClinical careLack of knowledgeSystematic reviewSnowball techniqueLiterature searchPhysiotherapyHealthExclusion criteriaAdultsCare[Association of lifestyle and apolipoprotein E gene with risk for cognitive frailty in elderly population in China].
Zhong W, Wang X, Song W, Li C, Chen H, Chen Z, Lyu Y, Li Z, Shi X, Mao C. [Association of lifestyle and apolipoprotein E gene with risk for cognitive frailty in elderly population in China]. Chinese Journal Of Epidemiology 2024, 45: 41-47. PMID: 38228523, DOI: 10.3760/cma.j.cn112338-20231027-00254.Peer-Reviewed Original ResearchConceptsCognitive frailtyCox proportional hazards regression modelsProportional hazards regression modelsPhysical activityHazards regression modelsHealthy lifestyleLevels of physical activityChinese Longitudinal Healthy Longevity SurveyElderly populationRegular physical activityDietary diversityLevel of dietary diversityAssociation of lifestyleAPOE geneImpact of lifestyleRegression modelsAdditive interactionAPOE e4 alleleLifestyle scoreCombined lifestyleLongevity SurveyPhysical frailtyStudy participantsElderly personsLifestyle
2023
Health policy considerations for combining exercise prescription into noncommunicable diseases treatment: a narrative literature review
Tao D, Awan-Scully R, Ash G, Gu Y, Pei Z, Gao Y, Cole A, Supriya R, Sun Y, Xu R, Baker J. Health policy considerations for combining exercise prescription into noncommunicable diseases treatment: a narrative literature review. Frontiers In Public Health 2023, 11: 1219676. PMID: 37849722, PMCID: PMC10577435, DOI: 10.3389/fpubh.2023.1219676.Peer-Reviewed Original ResearchConceptsExercise prescriptionNoncommunicable diseasesNoncommunicable disease preventionBenefits of exerciseHealth policy considerationsDisease treatmentPatients' life qualityLife qualityPopulation health statusRoutine careOutpatient settingHealth statusDisease preventionHealthy lifestyleEvidence baseLiterature reviewHealth policyNarrative literature reviewFitness levelHealthcare systemPrescriptionTreatmentFramework analysisExerciseReviewAssociation of Healthy Lifestyles with Non-Alcoholic Fatty Liver Disease: A Prospective Cohort Study in Chinese Government Employees
Ling Z, Zhang C, He J, Ouyang F, Qiu D, Li L, Li Y, Li X, Duan Y, Luo D, Xiao S, Shen M. Association of Healthy Lifestyles with Non-Alcoholic Fatty Liver Disease: A Prospective Cohort Study in Chinese Government Employees. Nutrients 2023, 15: 604. PMID: 36771311, PMCID: PMC9921275, DOI: 10.3390/nu15030604.Peer-Reviewed Original ResearchConceptsHealthy lifestyle factorsLifestyle factorsBody mass indexLow-risk factorsChinese government employeesAssociations of healthy lifestyleCohort studyHealthy lifestyle patternNon-sedentary behaviorIncidence of non-alcoholic fatty liver diseaseNormal body mass indexRisk of non-alcoholic fatty liver diseaseOR of NAFLDNon-alcoholic fatty liver diseaseProspective cohort studyLogistic regression modelsPhysical activityAssociated with non-alcoholic fatty liver diseaseHealthy lifestyleLifestyle patternsHealthy dietMass indexGovernment employeesFatty liver diseaseRegression modelsGenetic Risk Prediction for Prostate Cancer: Implications for Early Detection and Prevention
Seibert T, Garraway I, Plym A, Mahal B, Giri V, Jacobs M, Cheng H, Loeb S, Helfand B, Eeles R, Morgan T. Genetic Risk Prediction for Prostate Cancer: Implications for Early Detection and Prevention. European Urology 2023, 83: 241-248. PMID: 36609003, DOI: 10.1016/j.eururo.2022.12.021.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsTimes higher riskGenetic risk scoreHigh genetic risk scoreLethal prostate cancerProstate cancerHigh genetic riskHigh riskRare pathogenic mutationsHealthy lifestyleEarly detectionPCa riskRisk predictionHigh-grade prostate cancerGenetic riskAggressive prostate cancerProstate cancer riskGenetic risk assessmentDNA damage repair genesGenetic risk predictionPCa mortalityAggressive diseaseLeading causeFamily historyCancer riskElevated risk
2022
Temporal associations between physical activity and three types of problematic use of the internet: A six-month longitudinal study
Huang P, Chen J, Potenza M, Griffiths M, Pakpour A, Chen J, Lin Y, Hung C, O'Brien K, Lin C. Temporal associations between physical activity and three types of problematic use of the internet: A six-month longitudinal study. Journal Of Behavioral Addictions 2022, 11: 1055-1067. PMID: 36427199, PMCID: PMC9881666, DOI: 10.1556/2006.2022.00084.Peer-Reviewed Original ResearchConceptsPhysical activity levelsPhysical activityActivity levelsTemporal associationInternational Physical Activity Questionnaire-Short FormHigher physical activity levelsLow physical activityQuestionnaire-Short FormPrevalence ratesDaily livingPositive temporal associationHealthy lifestyleLongitudinal survey studyTime pointsLongitudinal studySix-month longitudinal studyShort formAdditional investigationEffects modelProblematic useAssociationPresent studySurvey studyAddiction ScaleOnline surveyAssociations of Socioeconomic Status and Healthy Lifestyle With Incidence of Dyslipidemia: A Prospective Chinese Governmental Employee Cohort Study
Li L, Ouyang F, He J, Qiu D, Luo D, Xiao S. Associations of Socioeconomic Status and Healthy Lifestyle With Incidence of Dyslipidemia: A Prospective Chinese Governmental Employee Cohort Study. Frontiers In Public Health 2022, 10: 878126. PMID: 35757615, PMCID: PMC9218108, DOI: 10.3389/fpubh.2022.878126.Peer-Reviewed Original ResearchConceptsIncidence of dyslipidemiaHealthy lifestyleLifestyle scoreSocioeconomic inequalitiesHigher SESLow SESSocial determinants of healthAssociation of socioeconomic statusCumulative incidence of dyslipidemiaPhysician-diagnosed dyslipidemiaHealthy lifestyle behaviorsReduce socioeconomic inequalitiesDeterminants of healthAssociation of SESLipid-lowering drug useParticipants' mean ageLipoprotein cholesterolCox proportional hazards modelsHigh-density lipoprotein cholesterolLifestyle behaviorsPhysical activitySocial determinantsProportional hazards modelUnhealthy lifestylePrimary lifestylePediatric Preventive Care in Middle-High Resource Countries—The Padova Chart for Health in Children
Galderisi A, Perilongo G, Caprio S, Da Dalt L, Di Salvo G, Gatta M, Giaquinto C, Rizzuto R, Robb A, Sly PD, Simonelli A, Staiano A, Vettor R, Baraldi E. Pediatric Preventive Care in Middle-High Resource Countries—The Padova Chart for Health in Children. Frontiers In Pediatrics 2022, 10: 803323. PMID: 35498805, PMCID: PMC9047691, DOI: 10.3389/fped.2022.803323.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsNon-communicable diseasesHealthy lifestylePediatric preventive careHigh-resource countriesAssessment of necessityLifestyle interventionEntire age groupPreventive careCardiovascular healthLifetime riskRespiratory healthPreventive strategiesBrain plasticityHealthcare providersAge groupsResource countriesHealthcare promotionHealthy choicesPopulation basisUnprecedented pandemicInterventionSocial healthHealthChildrenChildhood
2021
Reflections on obesity-related health behaviors over time and suggestions for health promotion programs from African American women
Min H, Whittemore R, Kennedy HP, Nam S. Reflections on obesity-related health behaviors over time and suggestions for health promotion programs from African American women. Journal Of Women & Aging 2021, 34: 487-500. PMID: 34495818, PMCID: PMC8901798, DOI: 10.1080/08952841.2021.1974268.Peer-Reviewed Original ResearchConceptsFuture health promotion programsHealth promotion programsAA womenPromotion programsAfrican American womenHealth behaviorsHealthy lifestyleObesity-related health behaviorsYoung adulthoodPrimary health careAmerican womenCurrent qualitative descriptive studyWomen's perceptionsIssue of obesityCommunity-based programsWomen's suggestionsObesityHealthy behaviorsLifestyle componentsFirst main themeQualitative descriptive studyDescriptive studyMain themesMultifactorial phenomenonWomenDiet and Nutrition in Gynecological Disorders: A Focus on Clinical Studies
Afrin S, AlAshqar A, Sabeh M, Miyashita-Ishiwata M, Reschke L, Brennan JT, Fader A, Borahay MA. Diet and Nutrition in Gynecological Disorders: A Focus on Clinical Studies. Nutrients 2021, 13: 1747. PMID: 34063835, PMCID: PMC8224039, DOI: 10.3390/nu13061747.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsGynecological disordersDietary habitsPolycystic ovary syndromeCurrent clinical dataPotential confounding factorsPlant-derived natural compoundsOvary syndromeGynecological malignanciesVitamin DGynecological diseasesClinical dataClinical studiesUterine leiomyomaPhysical activityMediterranean dietConfounding factorsEpidemiological investigationsHealthy lifestyleHomeostatic functionsRed meatBalanced dietNutritional factorsNutritional dataDietDisorders
2020
Physical activity assessment among men undergoing genetic counseling for inherited prostate cancer: A teachable moment.
Giri V, Milliron B, Sinclair E, Obeid E, Smaltz C, Butryn M, Bruneau M. Physical activity assessment among men undergoing genetic counseling for inherited prostate cancer: A teachable moment. Journal Of Clinical Oncology 2020, 38: 360-360. DOI: 10.1200/jco.2020.38.6_suppl.360.Peer-Reviewed Original ResearchBody mass indexProstate cancerGenetic testingGenetic counselingPA guidelinesVigorous PAHealthy lifestyleLower body mass indexFuture lifestyle interventionsCurrent PA guidelinesOverweight/obesePhysical activity guidelinesSignificant predictorsLogistic regression analysisPhysical activity assessmentFrequency of PATeachable momentStrength-based activitiesLifestyle interventionPA adherencePCa aggressivenessActivity guidelinesMass indexPCa statusLifestyle questionnaire
2019
Organizational strategies to reduce physician burnout and improve professional fulfillment
Olson K, Marchalik D, Farley H, Dean SM, Lawrence EC, Hamidi MS, Rowe S, McCool JM, O'Donovan CA, Micek MA, Stewart MT. Organizational strategies to reduce physician burnout and improve professional fulfillment. Current Problems In Pediatric And Adolescent Health Care 2019, 49: 100664. PMID: 31588019, DOI: 10.1016/j.cppeds.2019.100664.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsPhysician burnoutConfidential mental health servicesElectronic health record usabilityEvidence-based recommendationsMental health servicesPhysician wellness programEvidence-based strategiesConsensus reviewPhysicians' professional fulfillmentHealth servicesSystematic reviewHealthy lifestyleHealth care organizationsPhysiciansProfessional fulfillmentWellness programsIndividual physiciansOrganization-based interventionsPeer supportPractice efficiencyInterventionMultiple institutionsPersonal resilienceReviewNegative outcomesGaps in provider lifestyle counseling and its adherence among obese adults with prediabetes and diabetes in the United States
Valero-Elizondo J, Aneni EC, Osondu CU, Grandhi GR, Virani SS, Nasir K. Gaps in provider lifestyle counseling and its adherence among obese adults with prediabetes and diabetes in the United States. Preventive Medicine 2019, 129: 105815. PMID: 31454663, DOI: 10.1016/j.ypmed.2019.105815.Peer-Reviewed Original ResearchConceptsLifestyle counselingObese adultsHealthcare providersManagement of obesityPrevalence of diabetesWeight loss programUS adult populationLevels of obesityLifestyle modificationDiabetes statusObese patientsSevere obesityLoss programMild obesityCardiovascular diseasePhysical activityObesity epidemicObesityDiabetesMetabolic diseasesAdult populationHealthy lifestyleCounselingPatientsAdults
2018
Relationships of Obesity-Related Behavior Patterns With Socioeconomic Status and Acculturation in Korean American Women
Jang M, Jeon S, Nam S, Song HJ, Whittemore R. Relationships of Obesity-Related Behavior Patterns With Socioeconomic Status and Acculturation in Korean American Women. Clinical Nursing Research 2018, 29: 440-447. PMID: 29932007, DOI: 10.1177/1054773818783467.Peer-Reviewed Original ResearchConceptsBody mass indexKorean American womenObesity-related behaviorsSocioeconomic statusPhysical activityAmerican womenLow physical activityRelationship of obesityCross-sectional studyHealthy diet groupMass indexDiet groupUnhealthy lifestyleFurther interventionSedentary behaviorSecondary analysisHealthy lifestyleWomenGroup differencesLifestyle groupHigher acculturationGroupLifestyleTwo-step cluster analysisStatus
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