2025
Hypertensive disorders of pregnancy and neuroimaging markers of dementia risk: A pilot study
Alshikho M, Haghighi N, Ravi R, Solomon V, Rangel E, Pyne J, Bista K, Chang J, Lippert R, Cotton‐Samuel D, Cedano S, De La Cruz Vasquez N, Haro C, Chiu J, Chen Y, Reddy U, McNeil B, Pemberton V, Yee L, Parrish T, Brickman A, Miller E, Investigators F. Hypertensive disorders of pregnancy and neuroimaging markers of dementia risk: A pilot study. Pregnancy 2025, 1 DOI: 10.1002/pmf2.70020.Peer-Reviewed Original ResearchHistory of HDPCerebral blood flowRegional cerebral blood flowWhite matter hyperintensityBrain MRIGray matter volumeHypertensive disordersRisk of cognitive declineAssociation of HDPSmall-for-gestational age infantsCognitive declineFractional anisotropyPilot studyHypertensive disorders of pregnancyRegional gray matter volumeWhite matter hyperintensity volumeMicrovascular brain injuryAssociated with long-term impairmentDisorders of pregnancyDementia riskMulticenter prospective cohortTrimester of pregnancyHigh-resolution brain MRIHealth StudyIndex deliveryBrain health PRO/Santé cerveau PRO: The development of a web-based program for dementia literacy and risk factor reduction
Belleville S, Anderson N, Bherer L, Camicioli R, Carrier J, Chan S, Cuesta M, Dang-Vu T, Dwosh E, Fiocco A, Ferland G, Gilbert B, Harris E, Itzhak I, Jarrett P, Kadri M, Laurin D, Liu-Ambrose T, McGibbon C, Middleton L, Miller L, Nygaard H, Montero-Odasso M, Murphy K, Phillips N, Pichora-Fuller M, Robillard J, Smith E, Speechley M, Trigui A, Wittich W, Chertkow H, Feldman H, Aging C. Brain health PRO/Santé cerveau PRO: The development of a web-based program for dementia literacy and risk factor reduction. The Journal Of Prevention Of Alzheimer's Disease 2025, 100134. PMID: 40090784, DOI: 10.1016/j.tjpad.2025.100134.Peer-Reviewed Original ResearchOnline educational programOlder adultsDementia riskEducation programsCommunity-dwelling older adultsIncreased risk of dementiaPilot studyBrain healthRisk of dementiaRisk factor reductionAbilities of older adultsCognitively stimulating activitiesModifiable risk factorsRisk profileWeb-based programProtective factorsSelf-report questionnairesDementia literacyIntervention MappingPhysical activityIndividual risk profileParticipant literacyDeterminants of riskLifestyle changesIntake questionnairePolygenic score integrating neurodegenerative and vascular risk informs dementia risk stratification
D'Aoust T, Clocchiatti‐Tuozzo S, Rivier C, Mishra A, Hachiya T, Grenier‐Boley B, Soumaré A, Duperron M, Le Grand Q, Bouteloup V, Proust‐Lima C, Samieri C, Neuffer J, Sargurupremraj M, Chêne G, Helmer C, Thibault M, Amouyel P, Lambert J, Kamatani Y, Jacqmin‐Gadda H, Tregouët D, Inouye M, Dufouil C, Falcone G, Debette S. Polygenic score integrating neurodegenerative and vascular risk informs dementia risk stratification. Alzheimer's & Dementia 2025, 21: e70014. PMID: 40042447, PMCID: PMC11881617, DOI: 10.1002/alz.70014.Peer-Reviewed Original ResearchConceptsOlder community-dwelling peopleCommunity-dwelling peopleDementia risk stratificationVascular contribution to dementiaAssociated with dementia riskGenetic riskDementia clinical trialsApo E4Polygenic risk scoresGenetic risk groupsHigh-risk individualsDementia riskImprove risk predictionEast Asian ancestryAD-PRSPopulation-basedPolygenic scoresRisk stratificationMemory-clinic patientsPrevention programsClinical risk factorsDementiaClinical participantsRisk scoreAlzheimer's diseaseExamining multimorbidity contributors to dementia over time
Klee M, Markwardt S, Elman M, Han L, Leist A, Allore H, Quiñones A. Examining multimorbidity contributors to dementia over time. Alzheimer's & Dementia 2025, 21: e14589. PMID: 39988573, PMCID: PMC11847647, DOI: 10.1002/alz.14589.Peer-Reviewed Original ResearchConceptsAverage attributable fractionDementia incidenceDementia riskAttributable fractionChronic conditionsAssociated with increased risk of dementiaHealth and Retirement Study participantsMedicare fee-for-service beneficiariesAcute myocardial infarctionFee-for-service beneficiariesRetirement Study participantsRisk of dementiaPatterns of comorbiditiesAssociated with increased riskDementia casesMyocardial infarctionClaims algorithmIncident casesADRDStudy participantsIschemic heart diseaseDementiaConfidence intervalsMultimorbidityHeart diseaseTailoring implementation strategies for the healthy actions and lifestyles to Avoid Dementia or Hispanos y el ALTo a la Demencia Program: Lessons learned from a survey study
Moukarzel S, Araujo-Menendez C, Galang E, Zlatar Z, Feldman H, Banks S, Group H. Tailoring implementation strategies for the healthy actions and lifestyles to Avoid Dementia or Hispanos y el ALTo a la Demencia Program: Lessons learned from a survey study. The Journal Of Prevention Of Alzheimer's Disease 2025, 12: 100053. PMID: 39827004, PMCID: PMC12184062, DOI: 10.1016/j.tjpad.2024.100053.Peer-Reviewed Original ResearchConceptsModifiable risk factorsNon-HispanicHealthy actionsCross-sectional study SETTINGTailored implementation strategiesDecreased dementia riskProgram participantsAssociated with higher interestSelf-administered surveySelf-rated satisfactionDementia programsDementia riskTailored ImplementationMixed-methods analysisIndependent of ethnicityExploratory factor analysisSociodemographic characteristicsOlder adultsStudy settingThematic analysisLifestyle changesProgram enrollmentIn-personProgram implementationImplementation strategies
2024
Robust, fully-automated assessment of cerebral perivascular spaces and white matter lesions: a multicentre MRI longitudinal study of their evolution and association with risk of dementia and accelerated brain atrophy
Barisano G, Iv M, Choupan J, Hayden-Gephart M, Weiner M, Aisen P, Petersen R, Jack C, Jagust W, Trojanowki J, Toga A, Beckett L, Green R, Saykin A, Morris J, Shaw L, Liu E, Montine T, Thomas R, Donohue M, Walter S, Gessert D, Sather T, Jiminez G, Harvey D, Donohue M, Bernstein M, Fox N, Thompson P, Schuff N, DeCarli C, Borowski B, Gunter J, Senjem M, Vemuri P, Jones D, Kantarci K, Ward C, Koeppe R, Foster N, Reiman E, Chen K, Mathis C, Landau S, Cairns N, Householder E, Reinwald L, Lee V, Korecka M, Figurski M, Crawford K, Neu S, Foroud T, Potkin S, Shen L, Kelley F, Kim S, Nho K, Kachaturian Z, Frank R, Snyder P, Molchan S, Kaye J, Quinn J, Lind B, Carter R, Dolen S, Schneider L, Pawluczyk S, Beccera M, Teodoro L, Spann B, Brewer J, Vanderswag H, Fleisher A, Heidebrink J, Lord J, Petersen R, Mason S, Albers C, Knopman D, Johnson K, Doody R, Meyer J, Chowdhury M, Rountree S, Dang M, Stern Y, Honig L, Bell K, Ances B, Morris J, Carroll M, Leon S, Householder E, Mintun M, Schneider S, Oliver A, Marson D, Griffith R, Clark D, Geld-macher D, Brockington J, Roberson E, Grossman H, Mitsis E, deToledo-Morrell L, Shah R, Duara R, Varon D, Greig M, Roberts P, Albert M, Onyike C, D’Agostino D, Kielb S, Galvin J, Pogorelec D, Cerbone B, Michel C, Rusinek H, de Leon M, Glodzik L, De Santi S, Doraiswamy P, Petrella J, Wong T, Arnold S, Karlawish J, Wolk D, Smith C, Jicha G, Hardy P, Sinha P, Oates E, Conrad G, Lopez O, Oakley M, Simpson D, Porsteinsson A, Goldstein B, Martin K, Makino K, Ismail M, Brand C, Mulnard R, Thai G, Mc Adams Ortiz C, Womack K, Mathews D, Quiceno M, Arrastia R, King R, Weiner M, Cook K, DeVous M, Levey A, Lah J, Cellar J, Burns J, Anderson H, Swerdlow R, Apostolova L, Tingus K, Woo E, Silverman D, Lu P, Bartzokis G, Radford N, Parfitt F, Kendall T, Johnson H, Farlow M, Hake A, Matthews B, Herring S, Hunt C, van Dyck C, Carson R, MacAvoy M, Chertkow H, Bergman H, Hosein C, Black S, Stefanovic B, Caldwell C, Hsiung G, Feldman H, Mudge B, Assaly M, Kertesz A, Rogers J, Trost D, Bernick C, Munic D, Kerwin D, Mesulam M, Lipowski K, Wu C, Johnson N, Sadowsky C, Martinez W, Villena T, Turner R, Johnson K, Reynolds B, Sperling R, Johnson K, Marshall G, Frey M, Yesavage J, Taylor J, Lane B, Rosen A, Tinklenberg J, Sabbagh M, Belden C, Jacobson S, Sirrel S, Kowall N, Killiany R, Budson A, Norbash A, Johnson P, Obisesan T, Wolday S, Allard J, Lerner A, Ogrocki P, Hudson L, Fletcher E, Carmichael O, Olichney J, DeCarli C, Kittur S, Borrie M, Lee T, Bartha R, Johnson S, Asthana S, Carlsson C, Potkin S, Preda A, Nguyen D, Tariot P, Fleisher A, Reeder S, Bates V, Capote H, Rainka M, Scharre D, Kataki M, Adeli A, Zimmerman E, Celmins D, Brown A, Pearlson G, Blank K, Anderson K, Santulli R, Kitzmiller T, Schwartz E, Sink K, Williamson J, Garg P, Watkins F, Ott B, Querfurth H, Tremont G, Salloway S, Malloy P, Correia S, Rosen H, Miller B, Mintzer J, Spicer K, Bachman D, Finger E, Pasternak S, Rachinsky I, Rogers J, Kertesz A, Drost D, Pomara N, Hernando R, Sarrael A, Schultz S, Ponto L, Shim H, Smith K, Relkin N, Chaing G, Raudin L, Smith A, Fargher K, Raj B. Robust, fully-automated assessment of cerebral perivascular spaces and white matter lesions: a multicentre MRI longitudinal study of their evolution and association with risk of dementia and accelerated brain atrophy. EBioMedicine 2024, 111: 105523. PMID: 39721217, PMCID: PMC11732520, DOI: 10.1016/j.ebiom.2024.105523.Peer-Reviewed Original ResearchConceptsRisk of dementiaDementia riskAccelerated brain atrophyLower risk of dementiaMeasures of cognitive functionLongitudinal studyUS National Institutes of HealthNational Institutes of HealthCombat dementiaInstitutes of HealthPerivascular spaces countAlzheimer's disease biomarkersUS National InstitutesClinical measures of cognitive functioningDementiaBrain healthMixed-effects modelsScreening toolClinical measuresConfounding factorsObservational studyCognitive declineLongitudinal trajectoriesParticipantsBrain atrophyCumulative anticholinergic exposure and white matter hyperintensity burden in community‐dwelling older adults
Li K, Krakauer C, Nelson J, Crane P, Andre J, Curl P, Yuh E, Mossa‐Basha M, Ralston J, Mac Donald C, Gray S. Cumulative anticholinergic exposure and white matter hyperintensity burden in community‐dwelling older adults. Journal Of The American Geriatrics Society 2024, 73: 1115-1124. PMID: 39697086, PMCID: PMC11971017, DOI: 10.1111/jgs.19325.Peer-Reviewed Original ResearchAnticholinergic exposureDementia riskAssociated with dementia riskCommunity-dwelling older adultsDementia risk factorsWhite matter hyperintensityThought (ACTMagnetic resonance imagingAssociated with greater WMH burdenCumulative anticholinergic exposureProspective cohort studyWhite matter hyperintensity burdenAdult ChangesRetrospective analysis of dataOlder adultsSemi-quantitative ratingsACT participantsLinear regression modelsTSDDsPrimary exposureAge-related white matter changesCohort studyWhite raceHyperintensity burdenDose-response relationshipAssociation Between Cumulative Anticholinergic Use and White Matter Hyperintensity Burden
Li K, Krakauer C, Nelson J, Crane P, Andre J, Curl P, Yuh E, Ralston J, Gray S, MacDonald C. Association Between Cumulative Anticholinergic Use and White Matter Hyperintensity Burden. Alzheimer's & Dementia 2024, 20: e084407. PMCID: PMC11714981, DOI: 10.1002/alz.084407.Peer-Reviewed Original ResearchMagnetic resonance imagingDose-response relationshipWhite matter hyperintensitiesAssociated with higher dementia riskAssociated with greater WMH burdenAnticholinergic useCumulative anticholinergic useKaiser Permanente WashingtonMagnetic resonance imaging scansThought (ACTAnticholinergic medication useProspective cohort studyWhite matter hyperintensity burdenDementia riskAdult ChangesWhite matter hyperintensities burdensOlder adultsAnticholinergic medicationsClinical indicationsAnticholinergic burdenCohort studyLinear regression modelsTSDDsMedication useResonance imagingHealth-Related Behaviors and Risk of Common Age-Related Brain Diseases Across Severities of Genetic Risk
Marini S, Kimball T, Mayerhofer E, Tack R, Senff J, Prapiadou S, Rivier C, Duskin J, Kourkoulis C, Falcone G, Yechoor N, Tanzi R, Rosand J, Singh S, Parodi L, Anderson C. Health-Related Behaviors and Risk of Common Age-Related Brain Diseases Across Severities of Genetic Risk. Neurology 2024, 103: e210014. PMID: 39504504, DOI: 10.1212/wnl.0000000000210014.Peer-Reviewed Original ResearchConceptsLate-life depressionGenetic riskDementia riskUK Biobank (UKBEffects of healthy lifestylesHealth-related behaviorsGenetic predispositionElevated genetic riskProspective cohort studyHazard of strokeCox proportional hazards modelsAge-related brain diseasesLifestyle behaviorsCare scoresUKB participantsProportional hazards modelHealthy lifestyleIncidence of strokeMultivariate Cox proportional hazards modelPolygenic scoresTargeted interventionsLifestyle adjustmentsAggregate risk estimatesRisk estimatesCohort studyF96. ALCOHOL USE AND DEMENTIA IN DIVERSE POPULATIONS
Topiwala A, Levey D, Zhou H, Deak J, Adhikari K, Ebmeier K, Bell S, Burgess S, Nichols T, Gaziano M, Stein M, Gelernter J. F96. ALCOHOL USE AND DEMENTIA IN DIVERSE POPULATIONS. European Neuropsychopharmacology 2024, 87: 256-257. DOI: 10.1016/j.euroneuro.2024.08.507.Peer-Reviewed Original ResearchMillion Veteran ProgramDementia riskMendelian randomizationDementia casesAlcohol usePrevalence of alcohol use disordersImpact of alcohol useRandom-effects meta-analysisAlcohol use disorder prevalenceProspective cohort studyStandard deviation increaseObservational associationsUK BiobankVeteran ProgramLevels of drinkingPopulation prevalenceAlcohol consumptionAlcohol use disorderCohort studyDisorder prevalenceDementiaDependent drinkersDose-response relationshipGenetic associationLight drinkersAssociations of Physical Activity Engagement with Cerebral Amyloid-β and Tau from Midlife
Gonzales M, Kojis D, Spartano N, Thibault E, DeCarli C, Fakhri G, Johnson K, Beiser A, Seshadri S. Associations of Physical Activity Engagement with Cerebral Amyloid-β and Tau from Midlife. Journal Of Alzheimer’s Disease 2024, 100: 935-943. PMID: 39031362, PMCID: PMC12050109, DOI: 10.3233/jad-240322.Peer-Reviewed Original ResearchConceptsPhysical activity indexPhysical activity engagementAssociated with lower dementia riskPhysical activity index scoreAssociation of physical activityActive engagementPhysical activity levelsFramingham Heart StudyCross-sectional associationsCommunity-based cohortCardiovascular risk factorsDementia riskPhysical activityLifestyle interventionHeart StudyLinear regression modelsStratified analysisTau-PET retentionSelf-ReportSex disparitiesActivity levelsLate lifeTau positron emission tomographyRisk factorsAge groupsTemporal trends in population attributable fractions of modifiable risk factors for dementia: a time-series study of the English Longitudinal Study of Ageing (2004–2019)
Chen S, Underwood B, Cardinal R, Chen X, Chen S, Amin J, Jin H, Huang J, Mueller C, Yan L, Brayne C, Kuper H. Temporal trends in population attributable fractions of modifiable risk factors for dementia: a time-series study of the English Longitudinal Study of Ageing (2004–2019). BMC Medicine 2024, 22: 268. PMID: 38926751, PMCID: PMC11210022, DOI: 10.1186/s12916-024-03464-2.Peer-Reviewed Original ResearchConceptsPopulation attributable fractionModifiable risk factorsEnglish Longitudinal Study of AgeingOverall PAFLongitudinal Study of AgingEnglish Longitudinal StudyPhysical inactivitySocioeconomic statusStudy of agingLower educationDementia riskSocial isolationAttributable fractionHearing lossRisk factorsTargeted public health strategiesTraumatic brain injuryProportion of dementiaDeterminants of dementiaSocioeconomic status categoriesEffective public health policiesDevelopment of evidence-basedPublic health strategiesPublic health policiesTime-series studyLongitudinal Patterns of Systolic Blood Pressure, Diastolic Blood Pressure, Cardiorespiratory Fitness, and Their Association With Dementia Risk: The HUNT Study
Lerfald M, Allore H, Nilsen T, Eldholm R, Martinez-Velilla N, Selbæk G, Ernstsen L. Longitudinal Patterns of Systolic Blood Pressure, Diastolic Blood Pressure, Cardiorespiratory Fitness, and Their Association With Dementia Risk: The HUNT Study. The Journals Of Gerontology Series A 2024, 79: glae161. PMID: 38894618, PMCID: PMC11266981, DOI: 10.1093/gerona/glae161.Peer-Reviewed Original ResearchEstimated cardiorespiratory fitnessCardiorespiratory fitnessDementia riskHUNT StudyRisk differenceAssociated with reduced dementia riskPopulation-based HUNT StudyAssociated with dementia riskOdds ratioPoor cardiorespiratory fitnessHigher cardiorespiratory fitnessRisk of dementiaEstimate odds ratiosRisk factorsModifiable risk factorsAge groupsAPOE e4 statusProspective cohort studyBlood pressureMultivariate logistic regressionHigh blood pressureMiddle-aged groupLongitudinal patternsE4 statusSystolic blood pressureTemporal trends and disparities of population attributable fractions of modifiable risk factors for dementia in China: a time-series study of the China health and retirement longitudinal study (2011–2018)
Chen S, Chen X, Hou X, Fang H, Liu G, Yan L. Temporal trends and disparities of population attributable fractions of modifiable risk factors for dementia in China: a time-series study of the China health and retirement longitudinal study (2011–2018). The Lancet Regional Health - Western Pacific 2024, 47: 101106. PMID: 38872868, PMCID: PMC11170192, DOI: 10.1016/j.lanwpc.2024.101106.Peer-Reviewed Original ResearchPopulation-attributable fractionModifiable risk factorsSocio-economic statusLower educationHearing lossChina HealthTraumatic brain injuryRisk factorsCalculate population-attributable fractionsTargeted public health strategiesRetirement Longitudinal StudySES disparitiesSocio-economic status groupsPopulation attributable fractionNew-onset dementiaEarly-life factorsPublic health strategiesSignificant public health challengePublic health challengeSex-specific analysesLower-income individualsTemporal trendsDementia riskPhysical inactivityAttributable fractionAssociation between experiencing low healthcare quality and developing dementia
Aravena J, Chen X, Levy B. Association between experiencing low healthcare quality and developing dementia. Journal Of The American Geriatrics Society 2024, 72: 2126-2132. PMID: 38415796, PMCID: PMC11226361, DOI: 10.1111/jgs.18842.Peer-Reviewed Original ResearchAssociated with increased dementia riskHealthcare qualityDementia riskHealthcare discriminationAssociated with greater dementia riskHazard ratioHealth and Retirement StudyDeterminants of dementiaCases of dementiaDementia prevalenceReducing dementiaPhysician diagnosisRetirement StudyHealthcare servicesOlder personsOlder adultsSocioeconomic factorsDementiaHealthcareImplement structural changesCognitive scoresCox regressionParticipantsHealthIndividual-level behaviorIncident dementia risk among patients with type 2 diabetes receiving metformin versus alternative oral glucose-lowering therapy: an observational cohort study using UK primary healthcare records
Doran W, Tunnicliffe L, Muzambi R, Rentsch C, Bhaskaran K, Smeeth L, Brayne C, Williams D, Chaturvedi N, Eastwood S, Dunachie S, Mathur R, Warren-Gash C. Incident dementia risk among patients with type 2 diabetes receiving metformin versus alternative oral glucose-lowering therapy: an observational cohort study using UK primary healthcare records. BMJ Open Diabetes Research & Care 2024, 12: e003548. PMID: 38272537, PMCID: PMC10823924, DOI: 10.1136/bmjdrc-2023-003548.Peer-Reviewed Original ResearchConceptsRisk of dementiaMild cognitive impairmentOral glucose-lowering therapyDementia riskObservational cohort studyAs-treated analysisGlucose-lowering therapyRisk of incident all-cause dementiaUK adultsCompare risk of dementiaIncident all-cause dementiaType 2 diabetesClinical Practice Research DatalinkActive comparator new user designCohort studyAll-cause dementiaPrimary healthcare recordsIncident dementia riskAssociated with lower riskPotential exposure misclassificationCox proportional hazards regressionMetformin useRisk of confoundingProportional hazards regressionIncident dementia
2023
Number of completed exercise sessions is associated with slower brain atrophy in MCI over 12 months in the EXERT trial
Digma L, Aslanyan V, Brewer J, Bevins E, Katula J, Chmelo E, Hodge H, LaCroix A, Shadyab A, Jacobs D, Salmon D, Feldman H, Pa J, Baker L. Number of completed exercise sessions is associated with slower brain atrophy in MCI over 12 months in the EXERT trial. Alzheimer's & Dementia 2023, 19 DOI: 10.1002/alz.079285.Peer-Reviewed Original ResearchSupervised exercise sessionsBrain atrophyExercise sessionsAlzheimer's Disease Cooperative StudyLess brain atrophySupervised exercise interventionLower dementia riskLate-life exerciseAmount of exerciseInferior lateral ventricleExercise armExercise interventionDementia riskBaseline ageCDR-SBAerobic trainingLateral ventricleHigh adherenceIntervention adherenceNumber of sessionsVentricular expansionExercise typePlasma Aβ42/40Amnestic MCICognitive declineOutcomes in Patients With Poststroke Seizures
Misra S, Kasner S, Dawson J, Tanaka T, Zhao Y, Zaveri H, Eldem E, Vazquez J, Silva L, Mohidat S, Hickman L, Khan E, Funaro M, Nicolo J, Mazumder R, Yasuda C, Sunnerhagen K, Ihara M, Ross J, Liebeskind D, Kwan P, Quinn T, Engel J, Mishra N. Outcomes in Patients With Poststroke Seizures. JAMA Neurology 2023, 80: 1155-1165. PMID: 37721736, PMCID: PMC10507596, DOI: 10.1001/jamaneurol.2023.3240.Peer-Reviewed Original ResearchConceptsPoststroke seizuresPoor functional outcomeLate seizuresEarly seizuresStroke subtypesFunctional outcomeOdds ratioSystematic reviewJoanna Briggs Institute toolsHemorrhagic stroke subtypesOutcomes of patientsHistory of strokeTrials of interventionsRisk of biasMeta-Analyses (PRISMA) checklistPreferred Reporting ItemsMeta-regression analysisWeb of ScienceRecurrent strokeGreater disabilityPoor outcomeDementia riskSubgroup analysisBias assessmentEgger's testFood insecurity and subjective cognitive complaints among adults aged ≥ 65 years from low- and middle-income countries
Smith L, López Sánchez G, Shin J, Kostev K, Underwood B, Oh H, Soysal P, Veronese N, Schuch F, Tully M, Koyanagi A. Food insecurity and subjective cognitive complaints among adults aged ≥ 65 years from low- and middle-income countries. European Journal Of Nutrition 2023, 62: 3217-3226. PMID: 37550594, PMCID: PMC10611875, DOI: 10.1007/s00394-023-03226-5.Peer-Reviewed Original ResearchConceptsSubjective cognitive complaintsSevere food insecurityMiddle-income countriesOlder adultsFood insecurityWorld Health OrganizationSCC scoreSubjective Cognitive Complaint ScaleCognitive complaintsImprove cognitive healthAssociated with subjective cognitive complaintsNationally representative dataDementia riskMultivariate linear regressionCognitive healthCommunity-BasedPerceived stressOlder peopleMethodsCross-sectionalAssessed associationsLearning complaintsGlobal ageConclusionFood insecurityLMICsRepresentative dataThe National Israel Brain Repository: Characterizing those who sign and do not sign intent to autopsy
Manzali S, Ravona‐Springer R, Ouyang Y, Lin H, Heymann A, Greenbaum L, Liraz‐Zaltsman S, Beeri M. The National Israel Brain Repository: Characterizing those who sign and do not sign intent to autopsy. Alzheimer's & Dementia 2023, 19 DOI: 10.1002/alz.064443.Peer-Reviewed Original ResearchCognitive characteristics of individualsCommunity-based study of individualsCompare cognitive functionOlder adultsOffspring of AD patientsRate of cognitive declinePostmortem human brainCognitive follow-upMiddle-aged offspringEpisodic memoryMotor functionStudy of individualsMaccabi Health ServicesCommunity-based studyMiddle-aged adultsCognitive functionBrain RepositoryCognitive trajectoriesCharacteristics of individualsCognitive characteristicsSelection biasCognitive declineDementia riskFollow-upHealth services
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply