2025
2070-LB: Modeling to Assess the Impact of Liquid, Stable Glucagon for Mini-dosing in Pediatrics—A Simulated Pharmacokinetic and Pharmacodynamic Study
FITCH R, MOULD D, SHERR J, LAFFEL L, NALLY L, FERGUSON N. 2070-LB: Modeling to Assess the Impact of Liquid, Stable Glucagon for Mini-dosing in Pediatrics—A Simulated Pharmacokinetic and Pharmacodynamic Study. Diabetes 2025, 74 DOI: 10.2337/db25-2070-lb.Peer-Reviewed Original ResearchMini-dose glucagonBaseline glucose levelsGlucagon doseGlucose levelsVisual predictive checkY/O groupMini-dosePediatric groupPediatric populationPharmacodynamic studiesClinical studiesPediatric studiesGlucose excursionsDose responseDoseAged 2Glucose responseAge-weight relationshipGlucagonImpending hypoglycemiaPredictive checksBaselineGlucoseMicro-dosingGroup
2024
Digital Gaming and Exercise Among Youth With Type 1 Diabetes: Cross-Sectional Analysis of Data From the Type 1 Diabetes Exercise Initiative Pediatric Study
Patton S, Gal R, Bergford S, Calhoun P, Clements M, Sherr J, Riddell M. Digital Gaming and Exercise Among Youth With Type 1 Diabetes: Cross-Sectional Analysis of Data From the Type 1 Diabetes Exercise Initiative Pediatric Study. JMIR Pediatrics And Parenting 2024, 7: e57198. PMID: 38889077, PMCID: PMC11186795, DOI: 10.2196/57198.Peer-Reviewed Original ResearchExercise sessionsPhysical activityMinutes of physical activityLevels of physical activityRegular physical activityType 1 diabetesCross-sectional analysisDigital gamesHealthy lifestyleActive wearablesGame sessionsExerciseInsulin useNondigital gamesDaily activitiesPediatric studiesSessionsContext of youthDisease statusYouthT1DCharacteristics of digital gamesInsulin pumpObservation periodContinuous glucose monitoringPostprandial Glucose Variability Following Typical Meals in Youth Living with Type 1 Diabetes
Patton S, Bergford S, Sherr J, Gal R, Calhoun P, Clements M, Riddell M, Martin C. Postprandial Glucose Variability Following Typical Meals in Youth Living with Type 1 Diabetes. Nutrients 2024, 16: 162. PMID: 38201991, PMCID: PMC10781146, DOI: 10.3390/nu16010162.Peer-Reviewed Original ResearchConceptsGlycemic variabilityGlucose variabilityType 1Continuous glucose monitoringPediatric studiesCarbohydrate intakeDay observation periodMacronutrient intakeDietary guidelinesPhysical activityExercise intensityT1DGlucose monitoringObservation periodTypical mealMeal contentMealIntakeCoefficient of variationAssociationMacronutrient contentMore carbohydratesCliniciansLarge sample
2023
The Acute Effects of Real-World Physical Activity on Glycemia in Adolescents With Type 1 Diabetes: The Type 1 Diabetes Exercise Initiative Pediatric (T1DEXIP) Study.
Riddell M, Gal R, Bergford S, Patton S, Clements M, Calhoun P, Beaulieu L, Sherr J. The Acute Effects of Real-World Physical Activity on Glycemia in Adolescents With Type 1 Diabetes: The Type 1 Diabetes Exercise Initiative Pediatric (T1DEXIP) Study. Diabetes Care 2023, 47: 132-139. PMID: 37922335, DOI: 10.2337/dc23-1548.Peer-Reviewed Original ResearchConceptsReal-world physical activityPhysical activityType 1Pediatric studiesHeart rateLower baseline HbA1c levelsReal-world observational studySelf-reported physical activityBaseline HbA1c levelsShorter disease durationPeak heart rateType 1 diabetesSelf-management strategiesDisease durationHbA1c levelsMedian durationLess hypoglycemiaLower BMIAcute effectsContinuous glucose monitoring dataObservational studyFood intakeEvent-level factorsInsulin dosingActive adolescents336-OR: Insulin Delivery Modality Does Not Impact Glycemic Change during Physical Activity in Youth with Type 1 Diabetes (T1D)—Results from the Real-World T1DEXI Pediatric Study
RIDDELL M, BERGFORD S, GAL R, PATTON S, CLEMENTS M, CALHOUN P, SHERR J. 336-OR: Insulin Delivery Modality Does Not Impact Glycemic Change during Physical Activity in Youth with Type 1 Diabetes (T1D)—Results from the Real-World T1DEXI Pediatric Study. Diabetes 2023, 72 DOI: 10.2337/db23-336-or.Peer-Reviewed Original ResearchInsulin delivery modalitiesPre-exercise glucoseJuvenile Diabetes Research FoundationPediatric studiesGlucose levelsDelivery modalitiesSpeakers bureauType 1 diabetesBlood glucose levelsInsulin delivery methodsNIH National InstituteAdvisory PanelGlycemic changesContinuous glucose monitorHarry B. Helmsley Charitable TrustPhysical activityExercise typeType 1Activity monitorDiabetesNovo NordiskEli LillyLeona M.Helmsley Charitable TrustT1D.17-year trends of body mass index, overweight, and obesity among adolescents from 2005 to 2021, including the COVID-19 pandemic: a Korean national representative study.
Ban C, Shin H, Eum S, Yon H, Lee S, Choi Y, Shin Y, Shin J, Koyanagi A, Jacob L, Smith L, Min C, Yeniova A, Kim S, Lee J, Yeo S, Kwon R, Koo M, Fond G, Boyer L, Acharya K, Kim S, Woo H, Park S, Shin J, Rhee S, Yon D. 17-year trends of body mass index, overweight, and obesity among adolescents from 2005 to 2021, including the COVID-19 pandemic: a Korean national representative study. European Review For Medical And Pharmacological Sciences 2023, 27: 1565-1575. PMID: 36876712, DOI: 10.26355/eurrev_202302_31399.Peer-Reviewed Original ResearchConceptsMean body mass indexBody mass indexPrevalence of obesityKorea Youth Risk Behavior Web-based SurveyMass indexTrends of body mass indexCOVID-19 pandemicYouth Risk Behavior Web-based SurveyKorean adolescentsNationally Representative StudyMean BMIWeb-based surveyPediatric studiesOverweightYouth obesityObesityPre-pandemic trendsRepresentative studyPrevalenceCOVID-19Investigate trendsResidential regionAnalyze trendsPre-pandemicPreventive measures
2022
Electrogastrography, Breath Tests, Ultrasonography, Transit Tests, Wireless Motility Capsule, and Cine-MRI
Arbizu R, Rodriguez L. Electrogastrography, Breath Tests, Ultrasonography, Transit Tests, Wireless Motility Capsule, and Cine-MRI. 2022, 207-220. DOI: 10.1007/978-3-031-15229-0_17.Peer-Reviewed Original ResearchWhole gut transitWireless motility capsuleGastrointestinal tractMotility capsuleBreath testMore pediatric studiesCine magnetic resonance imagingEvaluation of childrenWhole gastrointestinal tractMotility disordersGastric emptyingPediatric studiesNoninvasive testsMyoelectrical activityTransit testTransit studiesInvasive interventionsAdjunct testGut transitMotility studiesClinical diagnosisResonance imagingClinical settingLuminal volumeUltrasonography
2019
Long-term Follow-up of Severe Eosinophilic Hepatitis: A Rare Presentation of Hypereosinophilic Syndrome
Awadie H, Khoury J, Zohar Y, Yaccob A, Veitsman E, Saadi T. Long-term Follow-up of Severe Eosinophilic Hepatitis: A Rare Presentation of Hypereosinophilic Syndrome. Rambam Maimonides Medical Journal 2019, 10: e0020. PMID: 31545703, PMCID: PMC6824826, DOI: 10.5041/rmmj.10374.Peer-Reviewed Original ResearchEuropean Medicines AgencyYounger patientsPediatric studiesLong-term follow-upYoung personFDA black box warningBlack box warningYoung depressed patientsDrug developmentInstitutional review boardEosinophilic hepatitisHypereosinophilic syndromePlacebo treatmentDevelopmental pharmacologyRare presentationFollow-upDepressed patientsDiscrimination of childrenDrug treatmentAdult depressionEffective drugsEfficacy studiesUS FoodDrug AdministrationMedicines AgencyComplementary and Alternative Medicine Use in Children With Inflammatory Bowel Disease
Phatak U, Alper A, Pashankar DS. Complementary and Alternative Medicine Use in Children With Inflammatory Bowel Disease. Journal Of Pediatric Gastroenterology And Nutrition 2019, 68: 157-160. PMID: 30499887, DOI: 10.1097/mpg.0000000000002218.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsInflammatory bowel diseaseMind-body therapiesBowel diseaseCAM useConventional medicineAdverse effectsAlternative medicine useSafety of CAMUse of probioticsPediatric patientsPediatric studiesMedicine useAdult studiesSevere diseaseCommon reasonSmall studyAlternative medicineFish oilDiseaseTherapyChildrenDiet changeMedicinePatientsWidespread use
2017
Factors influencing plasma transfusion practices in paediatric intensive care units around the world
Karam O, Demaret P, Duhamel A, Shefler A, Spinella PC, Tucci M, Leteurtre S, Stanworth SJ, investigators T. Factors influencing plasma transfusion practices in paediatric intensive care units around the world. Vox Sanguinis 2017, 112: 140-149. PMID: 28176380, DOI: 10.1111/vox.12490.Peer-Reviewed Original ResearchConceptsPlasma transfusion practicesPlasma transfusionTransfusion practiceCoagulation testsPediatric intensive care unitInternational pediatric studiesLocal transfusion serviceAbnormal coagulation testsIntensive care unitEfficacy of transfusionSignificant relevant factorTransfusion policyTransfusion rateCare unitAppropriate indicationsPediatric studiesFrequent treatmentTransfusionResponse rateTransfusion servicesLocal investigatorsPatientsCenter characteristicsWide variationBleeding
2016
Electrogastrography, Breath Tests, Ultrasonography, Transit Tests, and SmartPill
Arbizu R, Rodriguez L. Electrogastrography, Breath Tests, Ultrasonography, Transit Tests, and SmartPill. 2016, 169-179. DOI: 10.1007/978-3-319-43268-7_15.ChaptersWhole gut transitBreath testMore pediatric studiesGastric myoelectrical activityWireless motility capsuleEvaluation of childrenWhole gastrointestinal tractMotility disordersGastric emptyingPediatric studiesNoninvasive testsMotility capsuleTransit testMyoelectrical activityGastrointestinal tractTransit studiesAdjunct testGut transitMotility studiesClinical settingElectrogastrographyRadiopaque markersNon-standardized methodologiesUltrasonographySmartPillAssociation of thrombophilia and catheter‐associated thrombosis in children: a systematic review and meta‐analysis
Neshat‐Vahid S, Pierce R, Hersey D, Raffini LJ, Faustino EV. Association of thrombophilia and catheter‐associated thrombosis in children: a systematic review and meta‐analysis. Journal Of Thrombosis And Haemostasis 2016, 14: 1749-1758. PMID: 27306795, PMCID: PMC5035642, DOI: 10.1111/jth.13388.Peer-Reviewed Original ResearchConceptsDeep vein thrombosisCatheter-associated thrombosisCentral venous catheter useElevated factor VIII levelsAssociation of thrombophiliaRoutine thrombophilia testingVenous catheter useCochrane Central RegisterPediatric risk factorsPooled prevalence rateFactor VIII levelsProtein C deficiencyRandom-effects modelWeb of ScienceThrombophilic traitsCatheter useCentral RegisterCohort studyFV Leiden mutationVein thrombosisControlled TrialsVenous thrombosisPediatric studiesRisk factorsOdds ratio
2015
Noninfectious Complications of Peritoneal Dialysis in Korean Children: A 26-Year Single-Center Study
Kim J, Park J, Oh J, Kim J, Lee J, Kim P, Shin J. Noninfectious Complications of Peritoneal Dialysis in Korean Children: A 26-Year Single-Center Study. Yonsei Medical Journal 2015, 56: 1359-1364. PMID: 26256980, PMCID: PMC4541667, DOI: 10.3349/ymj.2015.56.5.1359.Peer-Reviewed Original ResearchConceptsNoninfectious complications of PDComplication of peritoneal dialysisNoninfectious complications of peritoneal dialysisPeritoneal dialysisComplications of PDNoninfectious complicationsMetabolic complicationsIncidence of noninfectious complicationsDuration of PD therapyCause of end-stage renal diseaseEnd-stage renal diseaseCatheter-related complicationsSingle-center studyDuration of PDStatistically significant differenceCatheter removalOutflow failurePediatric patientsMechanical complicationsPediatric studiesRenal diseasePD therapyComplicationsGlomerular diseasePatients
2014
Hyperglycemia, Dysglycemia and Glycemic Control in Pediatric Critical Care
Agus M, Faustino E, Rigby M. Hyperglycemia, Dysglycemia and Glycemic Control in Pediatric Critical Care. 2014, 93-101. DOI: 10.1007/978-1-4471-6416-6_8.Peer-Reviewed Original ResearchGlycemic controlPediatric practitionersPoor outcomeProspective studyOrgan support measuresPediatric-specific dataPediatric-specific protocolsMore definitive dataHigher illness severityPediatric critical careInternational consensus statementProspective trialGlycemic managementIll patientsPediatric ICUIllness severityHigh morbidityHypoglycemic ratePatient populationPediatric intensivistsPediatric studiesSevere illnessIll childrenConsensus statementCritical care
2009
Changing Referral Trends of Acute Pancreatitis in Children: A 12‐year Single‐center Analysis
Park A, Latif SU, Shah AU, Tian J, Werlin S, Hsiao A, Pashankar D, Bhandari V, Nagar A, Husain SZ. Changing Referral Trends of Acute Pancreatitis in Children: A 12‐year Single‐center Analysis. Journal Of Pediatric Gastroenterology And Nutrition 2009, 49: 316-322. PMID: 19503003, PMCID: PMC3034387, DOI: 10.1097/mpg.0b013e31818d7db3.Peer-Reviewed Original ResearchConceptsTertiary care centerBody mass indexCases of pancreatitisAcute pancreatitisCare centerInclusion criteriaSingle tertiary care centerAcute pancreatitis casesPainful inflammatory disordersPediatric emergency departmentICD-9 codesPediatric pancreatitisPancreatitis casesCommon etiologyMass indexPediatric populationBiliary diseaseRecurrence rateRetrospective studyEmergency departmentInflammatory disordersMean agePediatric studiesReferral trendsPancreatitis
2008
Corpus callosum in maltreated children with posttraumatic stress disorder: A diffusion tensor imaging study
Jackowski AP, Douglas-Palumberi H, Jackowski M, Win L, Schultz RT, Staib LW, Krystal JH, Kaufman J. Corpus callosum in maltreated children with posttraumatic stress disorder: A diffusion tensor imaging study. Psychiatry Research 2008, 162: 256-261. PMID: 18296031, PMCID: PMC3771642, DOI: 10.1016/j.pscychresns.2007.08.006.Peer-Reviewed Original ResearchConceptsPosttraumatic stress disorderCorpus callosumStress disorderPathophysiology of PTSDDiffusion tensor imaging studyHistory of traumaWhite matter developmentEffects of stressWhite matter tractsWhite matter integrityDiffusion tensor imagingStudies of adultsInterhemispheric projectionsPediatric studiesPrimary white matter tractPreclinical studiesNormal controlsPosterior corpusHippocampus atrophyImaging studiesBrain structuresTensor imagingFractional anisotropyCallosumChildren
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