2025
Consideration of Sociodemographics in Machine Learning-Driven Sepsis Risk Prediction.
Hauschildt K, Pan A, Bernstein T, Admon A, Mukherjee B, Iwashyna T, Rountree L. Consideration of Sociodemographics in Machine Learning-Driven Sepsis Risk Prediction. Critical Care Medicine 2025 PMID: 40488579, DOI: 10.1097/ccm.0000000000006741.Peer-Reviewed Original ResearchSociodemographic dataNarrative reviewRisk predictionStratified analysisSociodemographicsSociodemographic biasesSystematic reviewInclusion criteriaAdult populationGoogle ScholarStudy typeReview studiesPubMedOutcomesGeographic heterogeneityReview articleSepsis-related outcomesInclusionRace/ethnicityReviewGastrointestinal oncologic emergencies: a radiologists’ guide
Wang M, Furrow M, Gao M, Nasrullah A, Shehata M, Shaaban A, Shenoy-Bhangle A, Revzin M, Katz D, Elsayes K. Gastrointestinal oncologic emergencies: a radiologists’ guide. Abdominal Radiology 2025, 1-11. PMID: 40464849, DOI: 10.1007/s00261-025-05012-9.Peer-Reviewed Original ResearchOncologic emergencyAirway-esophageal fistulaLife-threatening conditionPrevalence of cancerCancer related complicationsTreatment related effectsUnderlying malignancyIntestinal perforationSystemic manifestationsImaging manifestationsGastrointestinal bleedingRelated complicationsIntestinal ischemiaIntestinal obstructionCancer stageCancer patientsBowel changesGastrointestinal systemCancerMalignancyReview articleFistulaBleedingMetastasisComplicationsArrhythmic Mitral Valve Prolapse: Pathophysiology, Diagnostics, and Management Strategies
Kang J, van Kampen A, Dieterlen M, Spampinato R, Sundt T, Melnitchouk S, Levine R, Borger M. Arrhythmic Mitral Valve Prolapse: Pathophysiology, Diagnostics, and Management Strategies. Seminars In Thoracic And Cardiovascular Surgery 2025 PMID: 40189179, PMCID: PMC12212166, DOI: 10.1053/j.semtcvs.2025.03.005.Peer-Reviewed Original Research
2024
Comparisons of management approaches in neonatal opioid withdrawal syndrome: The eat, sleep, console approach vs. the Finnegan approach
Johnson K, Berkwitt A, Yankova L, Osborn R. Comparisons of management approaches in neonatal opioid withdrawal syndrome: The eat, sleep, console approach vs. the Finnegan approach. Seminars In Perinatology 2024, 49: 152021. PMID: 39736490, DOI: 10.1016/j.semperi.2024.152021.Peer-Reviewed Original ResearchGreater Detail Is Needed When Reporting Schenck Knee Dislocation V Injuries in the Orthopaedic Literature: A Systematic Review
Marcel A, Levitt S, Green J, Moran J, Jokl P, Schenck R, Wascher D, Alaia M, Medvecky M. Greater Detail Is Needed When Reporting Schenck Knee Dislocation V Injuries in the Orthopaedic Literature: A Systematic Review. Arthroscopy Sports Medicine And Rehabilitation 2024, 7: 101046. PMID: 40297088, PMCID: PMC12034068, DOI: 10.1016/j.asmr.2024.101046.Peer-Reviewed Original ResearchV injuriesSystematic reviewOrthopaedic literatureTear patternsKnee dislocationInclusion criteriaClasses I-IVPediatric patientsClassification systemMeta-analysisExclusion criteriaLigament tearsAnimal studiesPeriarticular fracturesFracture patternsI-IVCINAHLReview articleLigamentTechnique papersFractureKneeReviewRe-Evaluating the Transplant Glomerulopathy Lesion—Beyond Donor-Specific Antibodies
Chutani A, Guevara-Pineda D, Lerner G, Menon M. Re-Evaluating the Transplant Glomerulopathy Lesion—Beyond Donor-Specific Antibodies. Transplant International 2024, 37: 13365. PMID: 39640250, PMCID: PMC11617188, DOI: 10.3389/ti.2024.13365.Peer-Reviewed Original ResearchTransplant glomerulopathyLonger-term graft survivalCell-mediated immune mechanismsChronic allograft damageNon-HLA antibodiesDonor-specific antibodiesAnti-HLA alloantibodiesChronic allograft dysfunctionPathogenesis of transplant glomerulopathyPost-transplant yearComplement-mediated injuryShort-term outcomesAllograft dysfunctionAllograft damageGraft lossGraft survivalRenal transplantationEtiological diagnosisPodocyte stressHistological manifestationsImmune mechanismsMorphological lesionsGlomerulopathyTransplantationReview articleUse of sensitivity analyses to assess uncontrolled confounding from unmeasured variables in observational, active comparator pharmacoepidemiologic studies: a systematic review
Latour C, Delgado M, Su I, Wiener C, Acheampong C, Poole C, Edwards J, Quinto K, Stürmer T, Lund J, Li J, Lopez N, Concato J, Funk M. Use of sensitivity analyses to assess uncontrolled confounding from unmeasured variables in observational, active comparator pharmacoepidemiologic studies: a systematic review. American Journal Of Epidemiology 2024, 194: 524-535. PMID: 39098826, DOI: 10.1093/aje/kwae234.Peer-Reviewed Original ResearchUncontrolled confoundingEpidemiology journalsResidual confoundingSystematic reviewRobustness of studiesComparative cohort studyActive comparator cohort studyMedical journal articlesCohort studyConfoundingJournal articlesPharmacoepidemiological studiesSensitivity analysisPotential biasAssess robustnessMeasured variablesUnmeasured variablesPotential concernReview articleStudyJournalsVariables
2023
Addition of dexamethasone to prolong peripheral nerve blocks: a ChatGPT-created narrative review
Wu C, Cho B, Gabriel R, Hurley R, Liu J, Mariano E, Mathur V, Memtsoudis S, Grant M. Addition of dexamethasone to prolong peripheral nerve blocks: a ChatGPT-created narrative review. Regional Anesthesia & Pain Medicine 2023, 49: 777-781. PMID: 37295794, DOI: 10.1136/rapm-2023-104646.Peer-Reviewed Original ResearchPeripheral nerve blocksNerve blockGenerative Pre-trained TransformerAddition of dexamethasonePre-trained transformersPain medicineArtificial intelligence chatbotsRegional anesthesiaIntelligent chatbotHuman expertsChatGPTNarrative reviewDexamethasoneSearch methodologyLack of noveltyLay audiencesReview articleSubspecialtyAudiencePortal Hypertension in Alcohol-Associated Hepatitis
McConnell M, Iwakiri Y. Portal Hypertension in Alcohol-Associated Hepatitis. Current Hepatology Reports 2023, 22: 67-73. PMID: 37214274, PMCID: PMC10075503, DOI: 10.1007/s11901-023-00601-y.Peer-Reviewed Original ResearchAlcoholic hepatitisPortal hypertensionMajor public health problemAlcohol‐Associated HepatitisLiver-related morbidityPublic health problemReviewThis review articleIntrahepatic vasoconstrictionHospital admissionPortal inflowPerisinusoidal fibrosisHypertensionHealth problemsLiver vasculatureHepatitisClinical perspectiveMultiple possible mechanismsReview articlePossible mechanismPhlebosclerosisVasoconstrictionMorbidityInflammationAdmissionFibrosisPain Control with Regional Anesthesia in Patients at Risk of Acute Compartment Syndrome: Review of the Literature and Editorial View
Lam D, Pierson D, Salaria O, Wardhan R, Li J. Pain Control with Regional Anesthesia in Patients at Risk of Acute Compartment Syndrome: Review of the Literature and Editorial View. Journal Of Pain Research 2023, 16: 635-648. PMID: 36891457, PMCID: PMC9987529, DOI: 10.2147/jpr.s397428.Peer-Reviewed Original ResearchAcute compartment syndromePeripheral nerve blocksPain controlCompartment syndromeNerve blockRegional anesthesiaAdequate pain controlLong bone fracturesPaucity of literatureOpioid analgesiaAnalgesia treatmentDevastating complicationPain managementEpidural anesthesiaSurgical outcomesUnderlying injuryCardinal symptomsBone fracturesDifferential efficacyPatient safetyAnesthesiaPatientsSyndromeVulnerable groupsReview articleTolerance Induction in Vascularized Composite Allotransplantation—A Brief Review of Preclinical Models
Huelsboemer L, Kauke-Navarro M, Reuter S, Stoegner V, Feldmann J, Hirsch T, Kueckelhaus M, Dermietzel A. Tolerance Induction in Vascularized Composite Allotransplantation—A Brief Review of Preclinical Models. Transplant International 2023, 36: 10955. PMID: 36846605, PMCID: PMC9946984, DOI: 10.3389/ti.2023.10955.Peer-Reviewed Original ResearchConceptsTolerance inductionLong-term effectsAnimal modelsImmune systemDonor-specific toleranceLong-term outcomesRecipient's immune systemPreclinical animal modelsNovel therapeutic strategiesPre-clinical studiesVascularized Composite AllotransplantationChronic rejectionImmunosuppressive protocolsTransplant recipientsAllograft rejectionOrgan dysfunctionPreclinical modelsComposite allograftsTherapeutic strategiesComposite allotransplantationClinical practiceIS protocolClinical translationInductionReview articleComposition, Treatment, and Outcomes by Radiologically Defined Thrombus Characteristics in Acute Ischemic Stroke
Das S, Goldstein E, de Havenon A, Abbasi M, Nguyen T, de Sousa D, Yaghi S. Composition, Treatment, and Outcomes by Radiologically Defined Thrombus Characteristics in Acute Ischemic Stroke. Stroke 2023, 54: 1685-1694. PMID: 36661035, DOI: 10.1161/strokeaha.122.038563.Peer-Reviewed Original ResearchConceptsAcute ischemic strokeIschemic strokeAdvanced imaging modalitiesStroke treatmentOcclusive thrombusThrombus characteristicsTreatment modalitiesArterial thrombiNeurovascular imagingClot compositionPrevention strategiesTherapy modalitiesThrombusImaging modalitiesPatientsStrokeModalitiesFuture studiesFurther testingTreatmentReview articleClassification systemPathomechanismEpidemiologyImportant clues
2022
Dendritic Spines and Pain Memory
Benson C, King J, Reimer M, Kauer S, Waxman S, Tan A. Dendritic Spines and Pain Memory. The Neuroscientist 2022, 30: 294-314. PMID: 36461773, DOI: 10.1177/10738584221138251.Peer-Reviewed Original ResearchNeuropathic painDendritic spinesSynaptic transmissionSpinal cord dorsal hornForm of painNew therapeutic approachesSurface of neuronsDorsal hornIntractable painDeep laminaePain memoryTherapeutic approachesPainNervous systemNew therapeuticsSpineMillions of peopleInjuryDiseaseRecent studiesReview articlePrevalenceNeuronsImportant roleAugmentation of literature review of COVID-19 radiology
Merchant S, Nadkarni P, Shaikh M. Augmentation of literature review of COVID-19 radiology. World Journal Of Radiology 2022, 14: 342-351. PMID: 36186515, PMCID: PMC9521431, DOI: 10.4329/wjr.v14.i9.342.Peer-Reviewed Original ResearchFluorodeoxyglucose positron emission tomographyCOVID-19 manifestationsCOVID-19 pneumoniaCoronavirus disease 2019 (COVID-19) pandemicCardiac magnetic resonanceRole of radiologyDisease 2019 pandemicPositron emission tomographyAdditional radiological featuresPulmonary destructionRadiological featuresPulmonary infarctsRadiographic findingsCOVID-19 imagingEmission tomographyAdditional signsLiterature reviewRadiological imagesComprehensive review articleMagnetic resonanceReview articleEpigenetics of alcohol-related liver diseases
Habash N, Sehrawat T, Shah V, Cao S. Epigenetics of alcohol-related liver diseases. JHEP Reports 2022, 4: 100466. PMID: 35462859, PMCID: PMC9018389, DOI: 10.1016/j.jhepr.2022.100466.Peer-Reviewed Original ResearchAlcohol-related liver diseaseLiver diseaseMajor public health problemChronic liver diseasePublic health problemProinflammatory roleSignificant morbidityMultiple disease statesHealth problemsDisease statesDiseaseClinical applicationNon-coding RNADiagnosisEpigenetic alterationsPrimary causeCurrent knowledgeEpigenetic changesReview articleStudy of epigeneticsHepatologistsMorbidityComplicationsChemokinesPathophysiology
2021
Seeking progress in disease modification in Parkinson disease
Lungu C, Cedarbaum J, Dawson T, Dorsey E, Faraco C, Federoff H, Fiske B, Fox R, Goldfine A, Kieburtz K, Macklin E, Matthews H, Rafaloff G, Saunders-Pullman R, Schor N, Schwarzschild M, Sieber B, Simuni T, Surmeier D, Tamiz A, Werner M, Wright C, Wyse R. Seeking progress in disease modification in Parkinson disease. Parkinsonism & Related Disorders 2021, 90: 134-141. PMID: 34561166, PMCID: PMC11770554, DOI: 10.1016/j.parkreldis.2021.09.006.Peer-Reviewed Original ResearchConceptsDisease modificationParkinson's diseaseDisease-modifying benefitsNovel trial designsDrug therapyPatient populationTrial failuresTherapeutic targetTrial designNeurological disordersRelevant biomarkersTherapeutic developmentNational InstituteDiseaseReview articleResearch prioritiesKey stakeholder groupsFailureLikelihood of successTherapyStrokeBiomarkersTargeting the Hypoxic and Acidic Tumor Microenvironment with pH-Sensitive Peptides
Dharmaratne NU, Kaplan AR, Glazer PM. Targeting the Hypoxic and Acidic Tumor Microenvironment with pH-Sensitive Peptides. Cells 2021, 10: 541. PMID: 33806273, PMCID: PMC8000199, DOI: 10.3390/cells10030541.Peer-Reviewed Original ResearchConceptsNucleic acid analoguesPH-sensitive peptideLow insertion peptideAcidic tumor microenvironmentPoor bioavailabilityInsertion peptideFluorescent dyeHigh toxicitySelective deliveryAcid analoguesSmall molecule inhibitorsNanoparticlesCancer therapeuticsMolecule inhibitorsDyePeptidesReview articleAcidityPHLIPPromising toolBioavailabilityAnaloguesDeliveryHypoxic tumor microenvironmentAn integrative medicine review of primary prevention of allergy in pediatrics
Boolchandani H, Horwitz R, Soffer G. An integrative medicine review of primary prevention of allergy in pediatrics. Complementary Therapies In Medicine 2021, 58: 102695. PMID: 33636296, DOI: 10.1016/j.ctim.2021.102695.Peer-Reviewed Original ResearchConceptsAtopic diseasesAllergic diseasesPrimary preventionIntegrative medicineIntegrative medicine approachesLong-term outcomesNarrative review articlePrevention of diseaseMedicine ReviewsCounseling patientsPediatric populationAllergy preventionMedicine approachDiseasePreventionAllergyMedicineReview articlePatientsPregnancyPediatricsPrevalenceSensitization
2020
Nutrition, dietary habits, and weight management to prevent and treat patients with peripheral artery disease
Sagris M, Kokkinidis DG, Lempesis IG, Giannopoulos S, Rallidis L, Mena-Hurtado C, Bakoyiannis C. Nutrition, dietary habits, and weight management to prevent and treat patients with peripheral artery disease. Reviews In Cardiovascular Medicine 2020, 21: 565-575. PMID: 33388001, DOI: 10.31083/j.rcm.2020.04.202.Peer-Reviewed Original ResearchConceptsPeripheral artery diseaseArtery diseaseDietary habitsAppropriate nutritional supportWeight loss interventionHealthy dietary habitsWeight management interventionsLoss interventionNutritional supportWeight managementPAD ratesDietary planGeneral populationPatientsAdvanced stageWestern populationsMost adultsDevastating consequencesDiseaseInterventionReview articleManagement interventionsObesePopulationHabitsArthrofibrosis of the Ankle
Velasco BT, Patel SS, Broughton KK, Frumberg DB, Kwon JY, Miller CP. Arthrofibrosis of the Ankle. Foot & Ankle Orthopaedics 2020, 5: 2473011420970463. PMID: 35097416, PMCID: PMC8564948, DOI: 10.1177/2473011420970463.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsExtensive physical therapyFuture therapeutic optionsSoft tissue traumaPathogenesis of arthrofibrosisScar tissue formationCommon etiologyInitial treatmentSignificant morbiditySurgical optionsTherapeutic optionsPhysical therapyAnkle dysfunctionTissue traumaArthrofibrosisAnkleLevel VTissue formationExpert opinionReview articleMorbidityPainSurgeryDysfunctionOptionsPathogenesis
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