2025
Polygenic risks for depression and neural responses to reward and punishment in young adults
Chen Y, Li H, Luo X, Li G, Ide J, Li C. Polygenic risks for depression and neural responses to reward and punishment in young adults. Biological Psychiatry Cognitive Neuroscience And Neuroimaging 2025 PMID: 40412620, DOI: 10.1016/j.bpsc.2025.05.008.Peer-Reviewed Original ResearchPolygenic risk scoresPunishment processingNeural responsesAchenbach Adult Self-ReportInfluence of genetic riskCortical activityAdult Self-ReportYoung adultsGenetic riskRisk of depressionGambling TaskAberrant rewardDrinking severityHuman Connectome ProjectDepression severityPublished routinesBrain responsesPolygenic riskDepression scoresSelf-ReportDepressionConnectome ProjectRewardBrain imagingPunishmentHypothalamic resting-state functional connectivity and self-evaluated aggression in young adults
Yao Y, Chen Y, Li C. Hypothalamic resting-state functional connectivity and self-evaluated aggression in young adults. Journal Of Psychiatric Research 2025, 182: 421-429. PMID: 39889403, PMCID: PMC11834083, DOI: 10.1016/j.jpsychires.2025.01.045.Peer-Reviewed Original ResearchConceptsResting-state functional connectivityAggression scoresLateral hypothalamusSex differencesHuman Connectome ProjectFunctional connectivityAchenbach Adult Self-ReportAdult Self-ReportYoung adultsManifestations of aggressionVoxel-wise regressionPublished routinesMotivated behaviorOccipital gyriAggressive behaviorSelf-ReportMental healthAggressionConnectome ProjectNeural pathwaysBehavioral traitsRSFCHypothalamusScoresAdults
2024
Gray matter volumetric correlates of the polygenic risk of depression: A study of the Human Connectome Project data
Fu X, Chen Y, Luo X, Ide J, Li C. Gray matter volumetric correlates of the polygenic risk of depression: A study of the Human Connectome Project data. European Neuropsychopharmacology 2024, 87: 2-12. PMID: 38936229, DOI: 10.1016/j.euroneuro.2024.06.004.Peer-Reviewed Original ResearchGray matter volumeRegional gray matter volumeGenetic risk of depressionPhenotype of depressionPolygenic risk scoresVoxel-based morphometryRisk of depressionAchenbach Adult Self-ReportRight cerebellum crus ICerebellar gray matter volumeAnterior cingulate volumesPathophysiology of depressionAnterior cingulate cortexCerebellum crus IDSM-oriented scalesMarkers of depressionLeft postcentral gyrusAdult Self-ReportRight gyrus rectusGenetic riskNeural endophenotypesHuman Connectome Project dataDrinking severityHuman Connectome ProjectCingulate volumesDeficient sleep, altered hypothalamic functional connectivity, depression and anxiety in cigarette smokers
Chen Y, Chaudhary S, Li G, Fucito L, Bi J, Li C. Deficient sleep, altered hypothalamic functional connectivity, depression and anxiety in cigarette smokers. Neuroimage Reports 2024, 4: 100200. PMID: 38605733, PMCID: PMC11008573, DOI: 10.1016/j.ynirp.2024.100200.Peer-Reviewed Original ResearchResting state functional connectivitySeverity of depressionPittsburgh Sleep Quality IndexMotivated behaviorNicotine dependenceFunctional connectivityPittsburgh Sleep Quality Index scoreAchenbach Adult Self-ReportSeverity of alcohol useAssociated with greater severityComorbid nicotine dependenceDeficient sleepAdult Self-ReportHypothalamic functional connectivityHuman Connectome ProjectAnxiety disordersAnxiety severityPublished routinesAnxiety symptomsCircuit dysfunctionGreater severityPsychiatric problemsSleep-wake cyclePoor sleep qualityNeural markers
2020
Caregiver and patient distress in young adults with new cancer diagnoses.
Baum L, Schremp E, Borinstein S, Friedman D. Caregiver and patient distress in young adults with new cancer diagnoses. Journal Of Clinical Oncology 2020, 38: e24165-e24165. DOI: 10.1200/jco.2020.38.15_suppl.e24165.Peer-Reviewed Original ResearchImpact of Events Scale-RevisedNCCN Distress ThermometerSub-scale scoresDistress ThermometerFinancial toxicityProblem listAdult Self-ReportMedian scoreCancer diagnosisMedian patientIntegration of caregiversAnxiety sub-scaleFamily health issuesEvent Scale-RevisedQuality of lifeFACT-GPCaregiver scoresMale caregiversFACT-GPatient distressSummary scoreMental healthLonger-term benefitsCaregiversEffective interventions
2011
Health Utilities for Children and Adults With Type 1 Diabetes
Lee JM, Rhee K, O'Grady MJ, Basu A, Winn A, John P, Meltzer DO, Kollman C, Laffel LM, Lawrence JM, Tamborlane WV, Wysocki T, Xing D, Huang ES. Health Utilities for Children and Adults With Type 1 Diabetes. Medical Care 2011, 49: 924-931. PMID: 21544001, PMCID: PMC3210197, DOI: 10.1097/mlr.0b013e318216592c.Peer-Reviewed Original ResearchConceptsParent-proxy reportsType 1 diabetesHealth utilityProxy reportsEnd-stage renal diseaseEnd-stage complicationsStage renal diseaseChild Self-ReportSelf-ReportSignificant differencesRenal diseaseAdult Self-ReportHigher overall QoLOverall QOLCurrent QoLOverall qualityHigher QoLQoLFunction of ageType 1DiabetesAdultsComplicationsMethods of assessmentChildren
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