2025
Healthy ageing in older adults with cardiovascular disease
Schmanske N, Ngo J, Kalra K, Nanna M, Damluji A. Healthy ageing in older adults with cardiovascular disease. European Heart Journal 2025, ehaf231. PMID: 40296653, DOI: 10.1093/eurheartj/ehaf231.Peer-Reviewed Original ResearchHealthy agingOlder adultsGeriatric syndromesCardiovascular diseasePrevalence of chronic diseasesPopulation of older adultsDevelopment of geriatric syndromesImpact of geriatric syndromesPromote healthy agingAccelerated biological agingBiological ageUS populationChronic diseasesPotential interventionsLife expectancyPublic healthOlder patientsEuropean populationsMedical technologyAgeAdultsPopulationDiseaseSyndromeSocioeconomic progressFactors Associated with Preoperative Attrition from a Large, Racially and Ethnically Representative Bariatric Program in the USA: A Single-Center Retrospective, Cohort Study
Hamid S, Butensky S, Graetz E, Olivares M, Schwartz J, Schneider E, Ghiassi S, Gibbs K. Factors Associated with Preoperative Attrition from a Large, Racially and Ethnically Representative Bariatric Program in the USA: A Single-Center Retrospective, Cohort Study. Obesity Surgery 2025, 35: 2390-2394. PMID: 40295326, DOI: 10.1007/s11695-025-07884-8.Peer-Reviewed Original ResearchConceptsFactors associated with attritionAssociated with decreased oddsObesity-related diseasesHispanic ethnicitySocial Vulnerability IndexStudy samplePreoperative attritionElectronic health recordsAcademic health systemAssociated with increased oddsAssociated with attritionRegional-level factorsMultivariate logistic regressionHealth recordsNon-HispanicHealth systemCompared individual-US populationIncreased oddsSurgical treatment of obesityCohort studyMedicare insuranceLogistic regressionMedicareOddsFamily Experience With Hospital Care Teams: A Qualitative Investigation.
Reynolds K, Zelazny S, Grob R, Parker A, Schlesinger M, Martino S. Family Experience With Hospital Care Teams: A Qualitative Investigation. Hospital Pediatrics 2025, 15: e179-e185. PMID: 40254297, DOI: 10.1542/hpeds.2023-007721.Peer-Reviewed Original ResearchConceptsFamily experiencesHospital typeHospital settingQuantitative assessments of patients' experiencesAssessment of patient experienceHospital care teamMedical conditionsQuality improvement effortsGuardians of childrenCare coordinationCare teamPatient experienceHospital careClinical qualityHospital experienceMedical traineesUS populationImprovement effortsQualitative interviewsPediatric hospitalParent interviewsService linesParental vigilanceHospitalCareA Meta-analysis of the Prevalence of Food Insecurity Among People Experiencing Housing Insecurity and Homelessness in the United States.
Jackson C, Hart C, Uribe-Lacy C, Yang P, Tsai J. A Meta-analysis of the Prevalence of Food Insecurity Among People Experiencing Housing Insecurity and Homelessness in the United States. Public Health Reports 2025, 333549241305349. PMID: 39760409, PMCID: PMC11705288, DOI: 10.1177/00333549241305349.Peer-Reviewed Original ResearchPrevalence of food insecurityOdds of food insecurityFood insecurityAssociated with increased odds of food insecurityHousing insecurityFactors associated with food insecurityMental health conditionsAssociated with decreased oddsAssociated with increased oddsMeta-analysisUnited StatesHealth conditionsUnique articlesUS populationMultisectoral coordinationSystematic reviewExperience symptomsComprehensive searchAcademic databasesPrevalenceInsecurityInstitutional supportHIHPeopleHomelessness
2024
Impact of Chimeric Antigen Receptor T-Cell Therapy on Survival in Patients with Diffuse Large B-Cell Lymphoma at the Population Level in the United States
Ramdhanny A, Vaughn J, Epperla N. Impact of Chimeric Antigen Receptor T-Cell Therapy on Survival in Patients with Diffuse Large B-Cell Lymphoma at the Population Level in the United States. Blood 2024, 144: 3745. DOI: 10.1182/blood-2024-211747.Peer-Reviewed Original ResearchDiffuse large B-cell lymphomaCAR-T cell therapyT-cell therapyChimeric antigen receptorChimeric antigen receptor T-cell therapyPresence of B symptomsLarge B-cell lymphomaB-cell lymphomaOverall survivalFood and Drug AdministrationRelative survivalB symptomsApproval of CAR-T cell therapyAdvent of chimeric antigen receptorCentral nervous system lymphomaMultivariable flexible parametric survival modelNervous system lymphomaMedian Follow-UpUS Food and Drug AdministrationPopulation-based cohort studySurveillance, EpidemiologyPeriod of diagnosisUS populationPersons per yearP-value <Quadrivalent Conjugate Vaccine and Invasive Meningococcal Disease in US Adolescents and Young Adults
Shin T, Wells C, Shoukat A, Potter-Schwartz L, Langevin E, Langley J, Galvani A, Moghadas S. Quadrivalent Conjugate Vaccine and Invasive Meningococcal Disease in US Adolescents and Young Adults. JAMA Network Open 2024, 7: e2443551. PMID: 39504021, PMCID: PMC11541638, DOI: 10.1001/jamanetworkopen.2024.43551.Peer-Reviewed Original ResearchConceptsInvasive meningococcal diseaseInvasive meningococcal disease casesCases of invasive meningococcal diseaseQuadrivalent conjugate vaccineUS adolescentsMeningococcal diseaseConjugate vaccineMenACWY vaccineIncidence rates of invasive meningococcal diseasePrevention of invasive meningococcal diseaseIncidence rateBurden of meningococcal diseaseUS adolescent populationUS populationYoung adultsImmunization of adolescentsIncidence of invasive meningococcal diseaseBayesian hierarchical Poisson regression modelsDecision analytical studyRate of invasive meningococcal diseaseMenACWY vaccination programUnvaccinated individualsDecision analytic modelHierarchical Poisson regression modelYears of ageThyroid Cancer Incidence During 2020 to 2021 COVID-19 Variant Waves
Bell R, Weinberger D, Venkatesh M, Fernandes-Taylor S, Francis D, Davies L. Thyroid Cancer Incidence During 2020 to 2021 COVID-19 Variant Waves. JAMA Otolaryngology - Head & Neck Surgery 2024, 150: 969-977. PMID: 39388144, PMCID: PMC11581733, DOI: 10.1001/jamaoto.2024.3146.Peer-Reviewed Original ResearchThyroid cancer incidenceThyroid cancer diagnosisCancer incidenceUS adultsCancer diagnosisRates of thyroid cancer diagnosisUndiagnosed casesThyroid cancer casesIncidence of thyroid cancerCases of thyroid cancerAdvanced stage cancerMain OutcomesCancer casesUS populationHistological typeIncidence rateThyroid cancerPopulation morbiditySize of cancerStudy analyzed trendsQuarterly ratesFollicular cancerMedullary cancerPapillary cancerAnaplastic cancerRacial and Ethnic Disparities in Age-Specific All-Cause Mortality During the COVID-19 Pandemic
Faust J, Renton B, Bongiovanni T, Chen A, Sheares K, Du C, Essien U, Fuentes-Afflick E, Haywood T, Khera R, King T, Li S, Lin Z, Lu Y, Marshall A, Ndumele C, Opara I, Loarte-Rodriguez T, Sawano M, Taparra K, Taylor H, Watson K, Yancy C, Krumholz H. Racial and Ethnic Disparities in Age-Specific All-Cause Mortality During the COVID-19 Pandemic. JAMA Network Open 2024, 7: e2438918. PMID: 39392630, PMCID: PMC11581672, DOI: 10.1001/jamanetworkopen.2024.38918.Peer-Reviewed Original ResearchConceptsCOVID-19 public health emergencyNon-HispanicPublic health emergencyOther Pacific IslanderExcess mortalityAlaska NativesUS populationExcess deathsRates of excess mortalityCross-sectional study analyzed dataYears of potential lifeMortality relative riskNon-Hispanic whitesCross-sectional studyPacific IslandersStudy analyzed dataAll-Cause MortalityEthnic groupsMortality disparitiesMortality ratioTotal populationDeath certificatesEthnic disparitiesMain OutcomesDecedent ageMajor Gaps in the Cascade of Care for Opioid Use Disorder
Arwady M, Delphin-Rittmon M, Volkow N. Major Gaps in the Cascade of Care for Opioid Use Disorder. JAMA 2024, 332: 701-702. PMID: 38935607, PMCID: PMC11694736, DOI: 10.1001/jama.2024.11977.Peer-Reviewed Original ResearchPersistent distress related to systemic racism among black veterans in the United States
Whealin J, Jegede O, Na P, Haeny A, Pietrzak R. Persistent distress related to systemic racism among black veterans in the United States. Journal Of Affective Disorders 2024, 365: 375-378. PMID: 39147153, DOI: 10.1016/j.jad.2024.08.052.Peer-Reviewed Original ResearchAdverse mental health sequelaeRisk of mental health problemsMilitary veteransIncreased risk of mental health problemsEthnic minority veteransSystemic racismMental health sequelaeMental health problemsUse of self-reportsEthnic minority populationsNationally Representative SampleUS military veteransMultinomial logistic regression analysisSignificant emotional burdenStudy periodNon-VeteransLogistic regression analysisEmotional burdenMinority veteransBlack veteransUS veteransHealth sequelaeBaseline assessmentHealthcare systemUS populationTemporal Trends and Racial Disparities in Long-Term Survival After Stroke
Robinson D, Ding L, Howard G, Stanton R, Khoury J, Sucharew H, Haverbusch M, Nobel L, Khatri P, Adeoye O, Broderick J, Ferioli S, Mackey J, Woo D, Rios La Rosa F, Flaherty M, Slavin S, Star M, Martini S, Demel S, Walsh K, Coleman E, Jasne A, Mistry E, Kleindorfer D, Kissela B. Temporal Trends and Racial Disparities in Long-Term Survival After Stroke. Neurology 2024, 103: e209653. PMID: 39008784, PMCID: PMC11249510, DOI: 10.1212/wnl.0000000000209653.Peer-Reviewed Original ResearchConceptsPremorbid functional statusFunctional statusRacial disparitiesAcute ischemic strokeBlack individualsPopulation-based stroke studyBlack raceEffect of black raceNational Death IndexAssociated with 5-year mortalityBaseline functional statusAcute ischemic stroke casesRisk of deathPhysician adjudicationIntracerebral hemorrhageDeath IndexIntracerebral hemorrhage casesUS populationICD codesGeneral populationCalendar yearLogistic regressionModified Rankin ScaleStroke StudyMedical recordsProjections of Endovascular Therapy–Eligible Patients With Stroke for the US Population
Mistry E, Khoury J, Kleindorfer D, Kissela B, Alwell K, Jasne A, Ferioli S, La Rosa F, Coleman E, Demel S, Walsh K, Slavin S, Star M, Haverbusch M, Mackey J, Woo D, Aziz Y, Heldner M, Fischer U, Jadhav A, Jovin T, Albers G, Nogueira R, Khatri P. Projections of Endovascular Therapy–Eligible Patients With Stroke for the US Population. Stroke 2024, 55: 2011-2019. PMID: 38934124, DOI: 10.1161/strokeaha.123.045766.Peer-Reviewed Original ResearchUS populationStudy of stroke incidenceEndovascular thrombectomyNational Institutes of Health Stroke ScalePrevalence of large vessel occlusionHealth Stroke ScaleIschemic strokeEVT-eligible patientsUnited StatesPopulation-basedPrestroke disabilityStroke systemsStroke incidenceYears of ageLarge vessel occlusionEligibility criteriaAcute ischemic strokePost Hoc AnalysisStroke ScaleObservational studyEligibilityAdult patientsTreatment indicationsHospitalized patientsNational InstituteCoverage of Indoor Smoking and Vaping Restrictions in the U.S., 1990–2021
Seidenberg A, Braganza K, Chomas M, Diaz M, Friedman A, Phillips S, Pesko M. Coverage of Indoor Smoking and Vaping Restrictions in the U.S., 1990–2021. American Journal Of Preventive Medicine 2024, 67: 494-502. PMID: 38876294, PMCID: PMC11600437, DOI: 10.1016/j.amepre.2024.06.007.Peer-Reviewed Original ResearchIndoor smoking restrictionsVaping restrictionsAmerican Nonsmokers' Rights FoundationSecondhand smoke exposureTobacco-related diseasesUS Census populationRisk of premature deathE-cigarette useNon-smoking adultsSmoking restrictionsIndoor smokingCensus populationUS populationSmoke exposureE-cigarettesComprehensive restrictionsCoverage of policyPremature deathLocal jurisdictionsPercentage of statesNational coverageE-cigarette aerosolUS statesNational residentsWorkplaceMP23-14 PREVALENCE OF LOWER URINARY TRACT SYMPTOMS IN THE US POPULATION: CONTEMPORARY ESTIMATES FROM THE RISE FOR HEALTH (RISE) STUDY
Sutcliffe S, Falke C, Fok C, Harlow B, Kenton K, Lewis C, Low L, Lowder J, Lukacz E, Markland A, McGwin G, Meister M, Mueller E, Newman D, Pakpahan R, Rickey L, Rockwood T, Smith A, Smith E, Rudser K, Smith A, Consortium F. MP23-14 PREVALENCE OF LOWER URINARY TRACT SYMPTOMS IN THE US POPULATION: CONTEMPORARY ESTIMATES FROM THE RISE FOR HEALTH (RISE) STUDY. Journal Of Urology 2024, 211: e387. DOI: 10.1097/01.ju.0001008776.99097.8a.14.Peer-Reviewed Original ResearchUS populationComparison of organ involvement clusters in Black and White American sarcoidosis patients from a prospectively collected patient registry
Harper L, Tauquir A, Huang S, Wang X, Schupp J, Baughman R, Culver D. Comparison of organ involvement clusters in Black and White American sarcoidosis patients from a prospectively collected patient registry. Respiratory Medicine 2024, 226: 107605. PMID: 38537782, PMCID: PMC11840713, DOI: 10.1016/j.rmed.2024.107605.Peer-Reviewed Original ResearchSelection, optimization and validation of ten chronic disease polygenic risk scores for clinical implementation in diverse US populations
Lennon N, Kottyan L, Kachulis C, Abul-Husn N, Arias J, Belbin G, Below J, Berndt S, Chung W, Cimino J, Clayton E, Connolly J, Crosslin D, Dikilitas O, Velez Edwards D, Feng Q, Fisher M, Freimuth R, Ge T, Glessner J, Gordon A, Patterson C, Hakonarson H, Harden M, Harr M, Hirschhorn J, Hoggart C, Hsu L, Irvin M, Jarvik G, Karlson E, Khan A, Khera A, Kiryluk K, Kullo I, Larkin K, Limdi N, Linder J, Loos R, Luo Y, Malolepsza E, Manolio T, Martin L, McCarthy L, McNally E, Meigs J, Mersha T, Mosley J, Musick A, Namjou B, Pai N, Pesce L, Peters U, Peterson J, Prows C, Puckelwartz M, Rehm H, Roden D, Rosenthal E, Rowley R, Sawicki K, Schaid D, Smit R, Smith J, Smoller J, Thomas M, Tiwari H, Toledo D, Vaitinadin N, Veenstra D, Walunas T, Wang Z, Wei W, Weng C, Wiesner G, Yin X, Kenny E. Selection, optimization and validation of ten chronic disease polygenic risk scores for clinical implementation in diverse US populations. Nature Medicine 2024, 30: 480-487. PMID: 38374346, PMCID: PMC10878968, DOI: 10.1038/s41591-024-02796-z.Peer-Reviewed Original ResearchConceptsPolygenic risk scoresPredictive performance of polygenic risk scoresPerformance of polygenic risk scoresPolygenic risk score performanceRisk scoreGenetic diversity dataElectronic medical recordsDiverse US populationStrength of evidenceDiverse clinical settingsDiverse adultsUS populationHispanic populationCardiometabolic diseasesGenetic ancestryProgram cohortGenetic resultsMedical recordsDiverse populationsMedical actionClinical settingProvidersRisk assessmentScoresDiverse data
2023
Prognosis and risk of suicide after cancer diagnosis
Kinslow C, Kumar P, Olfson M, Wall M, Petridis P, Horowitz D, Wang T, Kachnic L, Cheng S, Prigerson H, Yu J, Neugut A. Prognosis and risk of suicide after cancer diagnosis. Cancer 2023, 130: 588-596. PMID: 38018695, DOI: 10.1002/cncr.35118.Peer-Reviewed Original ResearchConceptsRisk of suicideCancer diagnosisSuicide riskCancer sitesMonths of diagnosisRelative risk of suicideSuicide deathsBaseline suicide riskSuicide ratesNewly diagnosed cancerYears of follow-upImpact of prognosisExistential distressAssociated with suicide riskMortality ratioWeighted linear regression modelImpending deathLinear regression modelsUS populationRelative riskGeneral populationBaseline riskAssociated with overall prognosisEnd Results databaseOverall survival rate2301. Viral Kinetics of Sequential SARS-CoV-2 Infections
Kissler S, Hay J, Fauver J, Mack C, Tai C, Anderson D, Ho D, Grubaugh N, Grad Y. 2301. Viral Kinetics of Sequential SARS-CoV-2 Infections. Open Forum Infectious Diseases 2023, 10: ofad500.1923. PMCID: PMC10677142, DOI: 10.1093/ofid/ofad500.1923.Peer-Reviewed Original ResearchSARS-CoV-2 infectionFaster clearance timesViral clearance timeSecond infectionVaccination statusClearance timeViral kineticsFirst infectionAcute SARS-CoV-2 infectionPrior SARS-CoV-2 infectionVaccine doseDisease coursePatient characteristicsPrior infectionOropharyngeal swabsImmune responseInfection historySubsequent infectionSequential infectionUS populationViral variantsInfectionHost factorsConvenience sampleConflicting resultsComparison of Projected Hemophilia a Populations Residing in Hospital Referral Regions with and without Hemophilia Treatment Centers in the US
Santaella M, Raimundo K, Schuldt R, Recht M. Comparison of Projected Hemophilia a Populations Residing in Hospital Referral Regions with and without Hemophilia Treatment Centers in the US. Blood 2023, 142: 3696. DOI: 10.1182/blood-2023-181009.Peer-Reviewed Original ResearchHospital referral regionsCenters for Disease Control and PreventionHemophilia treatment centersReferral regionsUS populationAdvance health equityCenters for Disease Control and Prevention estimatesImprove care accessDisease Control and PreventionControl and PreventionTreatment centersHealth equityCare accessAmerican Community SurveyOutreach clinicsVirtual appointmentsAdequate careRacial disparitiesHaemophilia A populationCareCommunity surveyMedian incomeDemographic characteristicsPWHARacial differencesDietary Patterns Among Individuals with Plasma Cell Disorders Compared to the General US Population
Traore K, Taneja A, Gorshein E, Castro F, Derkach A, Martinez J, Serrano E, Lesokhin A, Ahlstrom J, Block T, Hydren J, Usmani S, Shah U. Dietary Patterns Among Individuals with Plasma Cell Disorders Compared to the General US Population. Blood 2023, 142: 7363. DOI: 10.1182/blood-2023-186913.Peer-Reviewed Original ResearchBody mass indexPlasma cell disordersHigher HEI scoresFood frequency questionnaireGeneral US populationHEI scoresDietary patternsTotal fruit consumptionMultiple myelomaUS populationDietary interventionDietary guidelinesFruit consumptionCell disordersHealthy dietBlock Food Frequency QuestionnaireElevated body mass indexLower body mass indexCancer-specific mortalityLong-term outcomesHealthy Eating IndexNutrition Examination SurveyHealthy dietary habitsRole of nutritionOlder age groups
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