2025
Perioperative management of patients taking glucagon-like peptide 1 receptor agonists: Society for Perioperative Assessment and Quality Improvement (SPAQI) multidisciplinary consensus statement
Oprea A, Ostapenko L, Sweitzer B, Selzer A, Irizarry-Alvarado J, Hurtado Andrade M, Mendez C, Kelley K, Stewart E, Fernandez Robles C, Chadha R, Camilleri M, Mathur R, Umpierrez G, Hepner D. Perioperative management of patients taking glucagon-like peptide 1 receptor agonists: Society for Perioperative Assessment and Quality Improvement (SPAQI) multidisciplinary consensus statement. British Journal Of Anaesthesia 2025, 135: 48-78. PMID: 40379536, DOI: 10.1016/j.bja.2025.04.001.Peer-Reviewed Original ResearchConceptsGlucagon-like peptide 1 receptor agonistsPeptide 1 receptor agonistsPerioperative management of patientsMultidisciplinary consensus statementManagement of patientsSociety for Perioperative AssessmentPerioperative managementPerioperative assessmentConsensus statementPreoperative fasting timeMedical managementAgonistsModified Delphi processPatientsSystematic reviewCirrhosis and Truly Elective Major Surgery
Jakab S, Oprea A. Cirrhosis and Truly Elective Major Surgery. 2025, 249-258. DOI: 10.1093/med/9780190902001.003.0021.Peer-Reviewed Original ResearchPrevalence of chronic liver diseasePerioperative management of patientsPreoperative risk evaluationPresence of cirrhosisType of surgeryComplications of cirrhosisManagement of patientsEfficacy of therapyChronic liver diseaseLiver synthetic dysfunctionSynthetic dysfunctionOverall prognosisPostoperative complicationsDiagnosing cirrhosisPortal hypertensionLiver transplantationPerioperative managementPatient comorbiditiesSurgical proceduresCirrhosisLiver diseasePatientsSurgical teamScoring systemSurgery
2024
Perioperative Management of Patients Taking Glucagon-like Peptide-1 Receptor Agonists: Applying Evidence to Clinical Practice
Oprea A, Umpierrez G, Sweitzer B, Hepner D. Perioperative Management of Patients Taking Glucagon-like Peptide-1 Receptor Agonists: Applying Evidence to Clinical Practice. Anesthesiology 2024, 141: 1141-1161. PMID: 39471345, DOI: 10.1097/aln.0000000000005204.Peer-Reviewed Original ResearchRisk of Postoperative Complications After Total Hip and Total Knee Arthroplasty in Behcet Syndrome Patients
Ratnasamy P, Diatta F, Allam O, Kauke-Navarro M, Grauer J. Risk of Postoperative Complications After Total Hip and Total Knee Arthroplasty in Behcet Syndrome Patients. JAAOS Global Research And Reviews 2024, 8: e24.00040. PMID: 39392934, PMCID: PMC11469891, DOI: 10.5435/jaaosglobal-d-24-00040.Peer-Reviewed Original ResearchConceptsBehcet's syndromeAdverse eventsTotal knee arthroplastyMultivariate analysisRevision surgeryRisk of postoperative complicationsRisk of perioperative adverse eventsTotal hip arthroplastyLog-rank testElixhauser comorbidity index scoreRetrospective cohort studyMultisystem autoimmune disorderPostoperative adverse eventsPerioperative adverse eventsComorbidity Index scoreNational administrative databaseKnee arthroplastyTotal knee arthroplasty patientsPostoperative complicationsNo significant differencePatient ageAutoimmune disordersPerioperative managementSyndrome patientsCohort study
2023
Severe Pulmonary Hypertension Meets Intraperitoneal Surgery: No Place to Inflate?
Hickey T, Jayakumar S, Perrino A. Severe Pulmonary Hypertension Meets Intraperitoneal Surgery: No Place to Inflate? Cureus 2023, 15: e35318. PMID: 36968928, PMCID: PMC10038649, DOI: 10.7759/cureus.35318.Peer-Reviewed Original ResearchSevere pulmonary hypertensionPulmonary hypertensionPoor operative outcomesRight ventricular preloadRisk-benefit ratioElective cholecystectomyPneumoperitoneum resultsPerioperative managementVentricular preloadLaparoscopic approachOperative outcomesIntraperitoneal surgeryMechanical ventilationCardiac outputFavorable outcomeSuccessful case managementLaparoscopic proceduresCardiopulmonary insultCase managementMultidisciplinary approachHypertensionPatientsSurgeryOutcomesDeleterious effectsPerioperative Management of Extended-Release Buprenorphine: A Narrative Review and Case Series
Hickey T, Meeks T, Oxentine H, Park D, Abelleira A, Edens E, Gordon A, Acampora G. Perioperative Management of Extended-Release Buprenorphine: A Narrative Review and Case Series. Substance Abuse 2023, 44: 96-103. PMID: 37226900, DOI: 10.1177/08897077231167043.Peer-Reviewed Original ResearchConceptsExtended-release buprenorphinePerioperative managementPerioperative experienceNarrative reviewOutpatient inguinal hernia repairFull agonist opioidsSeries of patientsOpioid use disorderCases of patientsCommon clinical challengeInguinal hernia repairVariety of surgeriesDifferent medical centersDisorder treatment providersNationwide healthcare systemMultimodal analgesiaAgonist opioidsCase seriesBuprenorphine formulationsInpatient surgeryCase reportProspective dataClinical dataHernia repairClinical challenge
2022
Level of Evidence of Guidelines for Perioperative Management of Patients With Obstructive Sleep Apnea: An Evaluation Using the Appraisal of Guidelines for Research and Evaluation II Tool
Singh M, Tian C, Hyman J, Siddiqui S, Auckley D, Khanna A, Wong J, Englesakis M, Singh K, Ramachandran S. Level of Evidence of Guidelines for Perioperative Management of Patients With Obstructive Sleep Apnea: An Evaluation Using the Appraisal of Guidelines for Research and Evaluation II Tool. Anesthesia & Analgesia 2022, 136: 262-269. PMID: 36638510, DOI: 10.1213/ane.0000000000006320.Peer-Reviewed Original ResearchConceptsObstructive sleep apneaClinical practice guidelinesAppraisal of GuidelinesPerioperative managementPractice guidelinesSleep apneaMedical literaturePerioperative management decisionsPerioperative patient experienceGrading of RecommendationsEvaluation II (AGREE II) toolQuality of evidencePercent of recommendationsAGREE II scoresLevel of evidenceRigor of developmentMeta-Analyses (PRISMA) guidelinesQuality of guidelinesPreferred Reporting ItemsIntraclass correlation coefficientII scorePerioperative periodOxford classificationPatient partnersPatient experiencePreoperative Management of Cardiovascular Medications: A Society for Perioperative Assessment and Quality Improvement (SPAQI) Consensus Statement
Sahai SK, Balonov K, Bentov N, Bierle DMM, Browning LM, Cummings KC, Dougan BM, Maxwell M, Merli GJ, Oprea AD, Sweitzer B, Mauck KF, Urman RD. Preoperative Management of Cardiovascular Medications: A Society for Perioperative Assessment and Quality Improvement (SPAQI) Consensus Statement. Mayo Clinic Proceedings 2022, 97: 1734-1751. PMID: 36058586, DOI: 10.1016/j.mayocp.2022.03.039.Peer-Reviewed Original ResearchConceptsCardiovascular medicationsPerioperative assessmentAntiarrhythmic agentsReceptor antagonistAngiotensin receptor neprilysin inhibitorQuality Improvement (SPAQI) Consensus StatementAngiotensin II receptor blockersClass I antiarrhythmic agentsClass III antiarrhythmic agentII receptor blockersClasses of medicationsEndothelin receptor antagonistsPotassium-sparing diureticsCalcium channel blockersΒ-adrenoceptor blockersAdrenergic receptor antagonistPhosphodiesterase-5 inhibitorsEvidence-based recommendationsSodium channel blockersPotassium channel openersSympatholytic medicationsReceptor blockersPerioperative managementHeart failureLoop diureticsPerioperative Management of Extended-release Buprenorphine
Hickey TR, Henry JT, Edens EL, Gordon AJ, Acampora G. Perioperative Management of Extended-release Buprenorphine. Journal Of Addiction Medicine 2022, 17: e67-e71. PMID: 35862898, DOI: 10.1097/adm.0000000000001024.Peer-Reviewed Original ResearchStandardized Perioperative Protocol and Routine Ketorolac Use for Head and Neck Free Flap Reconstruction
Luthringer MM, Kim KG, Mukherjee TJ, Van Kouwenberg EA, Agag RL, Sinkin JC. Standardized Perioperative Protocol and Routine Ketorolac Use for Head and Neck Free Flap Reconstruction. Plastic & Reconstructive Surgery Global Open 2022, 10: e4318. PMID: 35572189, PMCID: PMC9094414, DOI: 10.1097/gox.0000000000004318.Peer-Reviewed Original ResearchNeck free flap reconstructionFree flap reconstructionStandardized perioperative protocolIntensive care unit lengthFlap reconstructionPerioperative protocolKetorolac useSingle-institution retrospective reviewNeck free flapsPerioperative ketorolacPerioperative regimensAnticoagulation regimenParenteral analgesicsPerioperative managementComplication rateConsecutive patientsRetrospective reviewPlatelet aggregation inhibitorsProtocol groupPotential complicationsFlap failureMicrovascular thrombosesFree flapMicrosurgical headPatientsPerioperative Management of Patients with Idiopathic Pulmonary Fibrosis Undergoing Noncardiac Surgery: A Narrative Review
Carr ZJ, Yan L, Chavez-Duarte J, Zafar J, Oprea A. Perioperative Management of Patients with Idiopathic Pulmonary Fibrosis Undergoing Noncardiac Surgery: A Narrative Review. International Journal Of General Medicine 2022, 15: 2087-2100. PMID: 35237071, PMCID: PMC8882471, DOI: 10.2147/ijgm.s266217.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsIdiopathic pulmonary fibrosisInterstitial lung diseaseIdiopathic interstitial pneumoniaIPF patientsNarrative reviewPerioperative managementHome oxygen useSafe perioperative carePostoperative pulmonary complicationsRetrospective cohort studyCardiopulmonary exercise testingOptimal perioperative managementPreoperative risk stratificationPulmonary function studiesWeb of ScienceAcute exacerbationARISCAT scorePostoperative pneumoniaPulmonary complicationsNoncardiac surgerySurgical populationCohort studyExercise testingInterstitial pneumoniaNeuraxial anesthesia23 Hematologic disorders
Oprea A. 23 Hematologic disorders. 2022, 465-496. DOI: 10.1016/b978-0-323-71860-8.00032-x.Peer-Reviewed Original ResearchPerioperative Buprenorphine Management A Multidisciplinary Approach
Hickey T, Abelleira A, Acampora G, Becker WC, Falker CG, Nazario M, Weimer MB. Perioperative Buprenorphine Management A Multidisciplinary Approach. 2022, 106: 169-185. PMID: 34823729, DOI: 10.1016/j.mcna.2021.09.001.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsMeSH KeywordsAcetaminophenAgedAnalgesics, Non-NarcoticAnalgesics, OpioidAnti-Inflammatory Agents, Non-SteroidalArthroplasty, Replacement, HipBuprenorphineCombined Modality TherapyDrug CompoundingFemaleHumansInterdisciplinary CommunicationMaleOpiate Substitution TreatmentOpioid-Related DisordersPainPain ManagementPain, PostoperativePerioperative CareReceptors, Opioid, muConceptsOpioid use disorderBuprenorphine treatmentMu-opioid receptor availabilityAgonist opioid treatmentMultimodal analgesic strategyAnti-inflammatory drugsLong-term buprenorphine treatmentAnalgesic strategiesNonopioid adjunctsOpioid treatmentPerioperative strategiesHospital dischargePerioperative managementBuprenorphine formulationsSimultaneous administrationRegional anesthesiaEffective treatmentUse disordersReceptor availabilityMultidisciplinary approachBuprenorphinePatientsTreatmentPainAnesthesia
2021
Mechanical Cardiac Circulatory Support: an Overview of the Challenges for the Anesthetist
Notarianni A, Tickoo M, Bardia A. Mechanical Cardiac Circulatory Support: an Overview of the Challenges for the Anesthetist. Current Anesthesiology Reports 2021, 11: 421-428. PMID: 34611458, PMCID: PMC8484296, DOI: 10.1007/s40140-021-00486-x.Peer-Reviewed Original ResearchExtracorporeal membrane oxygenationSalvage therapyEnd-stage heart failureMechanical circulatory support devicesAcute myocardial infarctionCirculatory support devicesVentricular assist deviceECMO utilizationPerioperative managementAnesthetic managementBalloon pumpHeart failureMembrane oxygenationCardiopulmonary supportDestination therapyMyocardial infarctionAnesthetic supportRecent FindingsUseMCS devicesAssist deviceHemodynamic principlesPatientsManagement guidelinesTherapySupport devicesPerioperative thrombocytopenia
Lombard FW, Popescu WM, Oprea AD, Kertai MD. Perioperative thrombocytopenia. Current Opinion In Anaesthesiology 2021, 34: 335-344. PMID: 33935182, DOI: 10.1097/aco.0000000000000999.Peer-Reviewed Original ResearchConceptsPlatelet countThrombopoietin receptor agonistsRisk of bleedingProphylactic platelet transfusionsProthrombin complex concentrateRecombinant factor VIIGood quality evidenceThreshold platelet countIntravenous immunoglobulinPreoperative thrombocytopeniaAsymptomatic patientsPerioperative strategiesPerioperative managementSevere bleedingAntifibrinolytic agentsPlatelet transfusionsComplex concentrateQuality evidenceFibrinogen levelsReceptor agonistPerioperative thrombocytopeniaPlatelet functionThrombin generationIntraoperative alternativeFactor VIIEndocrine emergencies in anesthesia
Fernandez-Robles C, Carr ZJ, Oprea AD. Endocrine emergencies in anesthesia. Current Opinion In Anaesthesiology 2021, 34: 326-334. PMID: 33935181, DOI: 10.1097/aco.0000000000000986.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsEndocrine disordersPerioperative managementOral hyperglycemic agentsPerioperative fluid resuscitationPerioperative glycemic managementSafe perioperative managementCommon endocrine disorderPerioperative time periodNumber of patientsBetter operative outcomesInvasive surgical techniquesCarcinoid syndromeEndocrine emergencyAdverse eventsFluid resuscitationGlycemic managementOperative outcomesAvoidable complicationsMedical managementComplex patientsSurgical techniqueHyperglycemic agentOptimal managementOperating roomDisordersSpecial Considerations – Indwelling Spinal Cord Stimulators and Intrathecal Pumps
Beals C, Chow R, Vadivelu N, Rajput K. Special Considerations – Indwelling Spinal Cord Stimulators and Intrathecal Pumps. 2021, 335-343. DOI: 10.1007/978-3-030-55262-6_25.ChaptersSpinal cord stimulatorContinuous opioid useChronic pain patientsPaucity of literatureIT clonidineCentral sensitizationMultimodal analgesiaSystemic medicationsOpioid toleranceOpioid usePerioperative managementPain patientsPain physiciansPump dysfunctionIntrathecal pumpNeuraxial anesthesiaAmbulatory surgeryLong actingRegional anesthesiaPatientsSurgeryUnique subsetNormal functionAnesthesiaStimulator
2020
Anticoagulation Management in Geriatric Orthopedic Trauma Patients
Morris J, O’Connor M. Anticoagulation Management in Geriatric Orthopedic Trauma Patients. Current Geriatrics Reports 2020, 9: 288-295. DOI: 10.1007/s13670-020-00345-3.Peer-Reviewed Original ResearchDirect oral anticoagulantsOral anticoagulantsAnticoagulation managementGeriatric orthopaedic trauma patientsNon-elective orthopaedic surgeryPerioperative anticoagulation managementRecent FindingsOur understandingHip fracture surgeryVitamin K antagonistsOrthopaedic trauma patientsProthrombin complex concentrateTeam-based approachAnticoagulation interruptionK antagonistsPerioperative anticoagulationPerioperative managementMore patientsTrauma patientsFracture surgeryGeriatric patientsComplex concentrateRegional anesthesiaGeriatric teamReversal agentsOrthopedic surgeryImplementation of a contextually appropriate pediatric emergency surgical care course in Uganda
Ullrich S, Kisa P, Ruzgar N, Okello I, Oyania F, Kayima P, Kakembo N, Sekabira J, Situma M, Ozgediz D. Implementation of a contextually appropriate pediatric emergency surgical care course in Uganda. Journal Of Pediatric Surgery 2020, 56: 811-815. PMID: 33183745, DOI: 10.1016/j.jpedsurg.2020.10.004.Peer-Reviewed Original ResearchConceptsSurgical emergencyCare courseHernia/hydrocele repairPediatric surgical carePediatric surgical workforceNonspecialist cliniciansFurther implementation studiesHydrocele repairPerioperative managementMiddle-income countriesNeonatal emergenciesProvider knowledgeIntestinal emergenciesSurgical carePediatric surgeonsCleft lipMultiple cadresThird courseMost childrenRural providersSurgical workforceEquipment shortagesImplementation studyCurrent literatureFirst descriptionAn Update on Systemic Sclerosis and its Perioperative Management
Carr ZJ, Klick J, McDowell BJ, Charchaflieh JG, Karamchandani K. An Update on Systemic Sclerosis and its Perioperative Management. Current Anesthesiology Reports 2020, 10: 512-521. PMID: 32904358, PMCID: PMC7455511, DOI: 10.1007/s40140-020-00411-8.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsPulmonary arterial hypertensionInterstitial lung diseaseArterial hypertensionPerioperative managementPerioperative careSystemic sclerosisLung diseaseProgressive end-organ dysfunctionLimited evidence-based guidanceGastric dysmotility disordersNumerous systemic manifestationsOrgan-based fibrosisEnd-organ dysfunctionOptimal perioperative careOptimal perioperative managementPerioperative myocardial infarctionImmune-mediated diseasesMulti-system involvementNumber of patientsEvidence-based guidanceCardiac sequelaeDysmotility disordersReviewSystemic sclerosisAirway challengePerioperative outcomes
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