2025
Comparison of 5 BMPs for their chondrogenic potentials and microfracture-mediated cartilage repair using heparin/PEAD coacervate sustained release polymer
Gao X, Wright N, Huard M, Tan J, Ruzbarsky J, Lu A, Chubb L, Tuan R, Philippon M, Wang Y, Huard J. Comparison of 5 BMPs for their chondrogenic potentials and microfracture-mediated cartilage repair using heparin/PEAD coacervate sustained release polymer. Bioactive Materials 2025, 52: 588-603. DOI: 10.1016/j.bioactmat.2025.06.031.Peer-Reviewed Original ResearchChondrogenic differentiation of human bone marrow mesenchymal stem cellsTreatment of cartilage defectsCartilage defect repairFibrocartilage repairCartilage repairChondrogenic potentialCartilage defectsSustained release polymerChondrogenic differentiationHuman bone marrow mesenchymal stem cellsDifferentiation of human bone marrow mesenchymal stem cellsRelease polymersBone marrow mesenchymal stem cellsMarrow mesenchymal stem cellsSurgical proceduresClinical challengeMesenchymal stem cellsDefect repairStem cellsMorphogenetic proteinsOsteoarthritis treatmentRepairTreatmentPolymerMicrofracture
2016
Cost‐Effectiveness of Tramadol and Oxycodone in the Treatment of Knee Osteoarthritis
Smith SR, Katz JN, Collins JE, Solomon DH, Jordan JM, Suter LG, Yelin EH, Paltiel AD, Losina E. Cost‐Effectiveness of Tramadol and Oxycodone in the Treatment of Knee Osteoarthritis. Arthritis Care & Research 2016, 69: 234-242. PMID: 27111538, PMCID: PMC5378156, DOI: 10.1002/acr.22916.Peer-Reviewed Original ResearchConceptsIncremental cost-effectiveness ratioQuality-adjusted life yearsOA patientsTKA outcomesKnee OA patientsKnee osteoarthritis treatmentInfluence of opioidsOsteoarthritis Policy ModelCost-effectiveness ratioConservative treatmentPain reductionPain reliefPersistent painKnee osteoarthritisMean ageTKA utilizationTreatment optionsOsteoarthritis treatmentLife yearsOxycodoneTramadolTKALifetime costsOpioidsOutcomes
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