2024
Association between inspired oxygen fraction and development of postoperative pulmonary complications in thoracic surgery: a multicentre retrospective cohort study
Douville N, Smolkin M, Naik B, Mathis M, Colquhoun D, Kheterpal S, Collins S, Martin L, Popescu W, Pace N, Blank R, Committee M, Aziz M, Blasberg J, Chang A, Freundlich R, O’Reilly-Shah V, Schonberger R. Association between inspired oxygen fraction and development of postoperative pulmonary complications in thoracic surgery: a multicentre retrospective cohort study. British Journal Of Anaesthesia 2024, 133: 1073-1084. PMID: 39266439, PMCID: PMC11619793, DOI: 10.1016/j.bja.2024.08.005.Peer-Reviewed Original ResearchPostoperative pulmonary complicationsOne-lung ventilationAssociated with postoperative pulmonary complicationsInspired oxygen fractionPulmonary complicationsThoracic surgeryLogistic regression modelsDevelopment of postoperative pulmonary complicationsIntraoperative inspired oxygen fractionDuration of one-lung ventilationReduce postoperative pulmonary complicationsMulticentre retrospective cohort studyComposite of postoperative pulmonary complicationsUS medical centresLung resection surgeryRetrospective multicentre studyThoracic surgical proceduresArea under the curveRetrospective cohort studyOxygen fractionExposure of interestResection surgeryMulticentre studyUnivariate analysisSurgical proceduresRecurrence-free survival after curative resection of non-small cell lung cancer between inhalational gas anesthesia and propofol-based total intravenous anesthesia: a multicenter, randomized, clinical trial (GAS TIVA trial): protocol description
Kim J, Yoon S, Song I, Lee K, Hwang W, Kim H, Lee D, Lim H, Kim S, Lee J, Hong B, Blank R, Pedoto A, Popescu W, Theresa G, Martin A, Patteril M, Pathanasethpong A, Thongsuk Y, Pisitpitayasaree T, Huang A, Yu H, Kapoor P, Kim K, Chi S, Ahn H. Recurrence-free survival after curative resection of non-small cell lung cancer between inhalational gas anesthesia and propofol-based total intravenous anesthesia: a multicenter, randomized, clinical trial (GAS TIVA trial): protocol description. Perioperative Medicine 2024, 13: 79. PMID: 39039548, PMCID: PMC11264408, DOI: 10.1186/s13741-024-00436-1.Peer-Reviewed Original ResearchNon-small cell lung cancerRecurrence-free survivalCurative resection of non-small cell lung cancerResection of non-small cell lung cancerCell lung cancerCurative resectionTotal intravenous anesthesiaPropofol-based total intravenous anesthesiaLung cancerRandomized trialsClinical trialsAnesthetic managementReducing cancer recurrence riskAmerican Society of Anesthesiologists physical statusPatient's written informed consentMicroscopic residual diseaseInstitutional review board approvalReduce tumor recurrenceLung resection surgeryMethodsThis double-blindInhibit tumor angiogenesisMulticenter randomized trialCancer recurrence riskCell-mediated immunityIntravenous anesthesia
2023
Performance Comparison of Pulmonary Risk Scoring Systems in Lung Resection
Zorrilla-Vaca A, Grant M, Rehman M, Sarin P, Mendez-Pino L, Urman R, Varelmann D. Performance Comparison of Pulmonary Risk Scoring Systems in Lung Resection. Journal Of Cardiothoracic And Vascular Anesthesia 2023, 37: 1734-1743. PMID: 37330329, DOI: 10.1053/j.jvca.2023.05.035.Peer-Reviewed Original ResearchConceptsPostoperative pulmonary complicationsLung resection surgeryRisk-scoring systemPulmonary complicationsResection surgeryScoring systemLung resectionRisk scoreRisk of PPCsRetrospective cohort study SETTINGLAS VEGASAlternative risk scoresSingle-center cohortCohort study SETTINGAdult patientsExpiratory volumeLung surgeryThoracic surgeryPulmonary riskConcordance indexSurgeryPatientsDiscriminatory powerStudy settingComplicationsPostoperative Hypoxemia After Dual-Controlled vs Volume-Controlled Ventilation in Lung Surgery
Zorrilla-Vaca A, Grant M, Rehman M, Sarin P, Varelmann D, Urman R. Postoperative Hypoxemia After Dual-Controlled vs Volume-Controlled Ventilation in Lung Surgery. The Annals Of Thoracic Surgery 2023, 116: 173-179. PMID: 36608756, DOI: 10.1016/j.athoracsur.2022.12.029.Peer-Reviewed Original ResearchConceptsLung resection surgeryPostoperative hypoxemiaResection surgeryPulmonary outcomesConventional ventilationAcute respiratory distress syndromeChronic obstructive pulmonary diseaseImproved pulmonary outcomesIntraoperative ventilator settingsPreoperative oxygen saturationSecondary pulmonary complicationsOne-lung ventilationObstructive pulmonary diseaseRespiratory distress syndromeLow tidal volumeVolume-controlled ventilationEligible patientsPRVC ventilationPulmonary complicationsRespiratory failureSecondary outcomesDistress syndromeLung surgeryPrimary outcomePulmonary disease
2022
Chapter 53 Enhanced Recovery After Thoracic Surgery
Teeter E, Afonso A, Popescu W. Chapter 53 Enhanced Recovery After Thoracic Surgery. 2022, 766-774. DOI: 10.1016/b978-0-323-71301-6.00053-6.Peer-Reviewed Original ResearchLung resection surgeryResection surgeryThoracic surgeryEnhanced recoveryBaseline functional statusAvoidance of complicationsPatient-centered careMultiple surgical specialtiesEvidence-based approachColorectal surgeryPerioperative periodFunctional statusRecent guidelinesSurgerySurgical specialtiesRecovery guidelinesGuidelinesEsophagectomyComplicationsEfficient returnRecoveryCareERAS
2021
A Lower Tidal Volume Regimen during One-lung Ventilation for Lung Resection Surgery Is Not Associated with Reduced Postoperative Pulmonary Complications.
Colquhoun DA, Leis AM, Shanks AM, Mathis MR, Naik BI, Durieux ME, Kheterpal S, Pace NL, Popescu WM, Schonberger RB, Kozower BD, Walters DM, Blasberg JD, Chang AC, Aziz MF, Harukuni I, Tieu BH, Blank RS. A Lower Tidal Volume Regimen during One-lung Ventilation for Lung Resection Surgery Is Not Associated with Reduced Postoperative Pulmonary Complications. Anesthesiology 2021, 134: 562-576. PMID: 33635945, PMCID: PMC8274370, DOI: 10.1097/aln.0000000000003729.Peer-Reviewed Original ResearchConceptsPositive end-expiratory pressureOne-lung ventilationPostoperative pulmonary complicationsEnd-expiratory pressurePulmonary complicationsProtective ventilationTidal volumeThoracic surgeryMajor postoperative pulmonary complicationsVentilation regimenLung resection surgeryRetrospective observational analysisThoracic Surgeons databaseMedian tidal volumeLung resection proceduresUnmatched cohortMajor surgeryPrimary outcomeResection surgerySurgeons databaseIndependent associationResection proceduresDecreased oddsIntraoperative dataComplications
2013
Fluid management in thoracic surgery
Assaad S, Popescu W, Perrino A. Fluid management in thoracic surgery. Current Opinion In Anaesthesiology 2013, 26: 31-39. PMID: 23262471, DOI: 10.1097/aco.0b013e32835c5cf5.Peer-Reviewed Original ResearchConceptsAcute kidney injuryAcute lung injuryLung resection surgeryResection surgeryThoracic surgeryFluid managementDevelopment of AKIDevelopment of ALIGoal-directed therapy protocolInadequate fluid resuscitationAdequate fluid managementCurrent available dataBaby lungKidney injuryPerioperative riskTissue hypoperfusionLung injuryFluid resuscitationFluid administrationSurgeryTherapy protocolsRestrictive protocolInjuryRecent findingsCapillary glycocalyx
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