2025
19 LONG-TERM OUTCOMES FOLLOWING SUBSTANTIAL DE-ESCALATION OF ELECTIVE RADIOTHERAPY DOSE AND VOLUME IN PATIENTS TREATED WITH DEFINITIVE CHEMORADIOTHERAPY FOR HUMAN PAPILLOMAVIRUS-ASSOCIATED OROPHARYNGEAL CANCER
Safavi A, Dee E, Tsai C, Wu Y, McBride S, Gelblum D, Yu Y, Chen L, Zakeri K, Shamseddine A, Kang J, Cracchiolo J, Wong R, Cohen M, Ganly I, Dunn L, Ho A, Sherman E, Riaz N, Lee N. 19 LONG-TERM OUTCOMES FOLLOWING SUBSTANTIAL DE-ESCALATION OF ELECTIVE RADIOTHERAPY DOSE AND VOLUME IN PATIENTS TREATED WITH DEFINITIVE CHEMORADIOTHERAPY FOR HUMAN PAPILLOMAVIRUS-ASSOCIATED OROPHARYNGEAL CANCER. Radiotherapy And Oncology 2025, 210: s11-s12. DOI: 10.1016/s0167-8140(25)04682-1.Peer-Reviewed Original ResearchDistant metastasis-free survivalConcurrent chemoradiotherapyLocoregional controlOropharyngeal cancerMD Anderson Dysphagia IndexQuality-of-lifeLR failureClinically meaningful changeHuman papillomavirus (HPV)-associated oropharyngeal cancerFollow-upHPV RNA in situ hybridizationSingle-institution retrospective cohort studyHPV-associated oropharyngeal cancerTwo-year locoregional controlNodal levelHuman papillomavirus-associated oropharyngeal cancerConed down volumeDefinitive concurrent chemoradiotherapyElective nodal failureHigh-dose cisplatinNode-negative neckMedian Follow-UpMetastasis-free survivalKaplan-Meier methodFive-year follow-up
2023
Pre-operative chemoradiotherapy with or without induction chemotherapy for operable locally-advanced esophageal cancer
Peters G, Talcott W, Peters N, Dhanasopan A, Lacy J, Cecchini M, Kortmansky J, Stein S, Lattanzi S, Park H, Boffa D, Johung K, Jethwa K. Pre-operative chemoradiotherapy with or without induction chemotherapy for operable locally-advanced esophageal cancer. Journal Of Gastrointestinal Oncology 2023, 14: 1181-1192. PMID: 37435226, PMCID: PMC10331751, DOI: 10.21037/jgo-22-1005.Peer-Reviewed Original ResearchProgression-free survivalMedian progression-free survivalOverall survivalIC-CRTInduction chemotherapySingle-institution retrospective cohort studyPre-operative chemoradiotherapyAdvanced esophageal cancerAdvanced esophageal carcinomaPathologic complete responseRetrospective cohort studyKaplan-Meier methodSubset of patientsProportional hazards regressionCycles of inductionAdenocarcinoma histologyCRT cohortCohort studyComplete responsePathologic responseTreatment cohortsDistant metastasisHazards regressionEsophageal cancerEsophageal carcinoma
2021
Examination of factors associated with lymph node metastases in lung carcinoids: Results from a single institution retrospective cohort study
Pathipati MP, Yohannan TK, Tian L, Hornbacker K, Benson JA, Berry GJ, Lui NS, Kunz PL, Padda SK. Examination of factors associated with lymph node metastases in lung carcinoids: Results from a single institution retrospective cohort study. Lung Cancer 2021, 154: 186-194. PMID: 33551175, PMCID: PMC8026717, DOI: 10.1016/j.lungcan.2021.01.017.Peer-Reviewed Original ResearchConceptsLung neuroendocrine tumorsLymph nodesNeuroendocrine tumorsLung carcinoidsSSTR imagingLN metastasisAtypical carcinoidExact testSingle-institution retrospective cohort studyLymph node-positive diseaseAssociation of lymphPositive lymph nodesRetrospective cohort studyLymph node diseaseLymph node involvementNode-positive diseaseLymph node metastasisMultivariable logistic regressionFisher's exact testPre-operative workupN2 diseaseAdjuvant therapyLN involvementN1 diseaseNode involvement
2020
Surgical approach for interval debulking after neoadjuvant chemotherapy for treatment of advanced ovarian cancer: A single-institution retrospective cohort study
Webster E, Dugan K, McNamara B, Lu L, Azodi M, Ratner E, Schwartz P, Menderes G. Surgical approach for interval debulking after neoadjuvant chemotherapy for treatment of advanced ovarian cancer: A single-institution retrospective cohort study. Gynecologic Oncology 2020, 159: 131. DOI: 10.1016/j.ygyno.2020.05.163.Peer-Reviewed Original ResearchSingle-institution retrospective cohort studyRetrospective cohort studyAdvanced ovarian cancerNeoadjuvant chemotherapyCohort studySurgical approachOvarian cancerChemotherapyCancerOphthalmic Emergency Department Visits: Factors Associated With Loss to Follow-up
Chen EM, Ahluwalia A, Parikh R, Nwanyanwu K. Ophthalmic Emergency Department Visits: Factors Associated With Loss to Follow-up. American Journal Of Ophthalmology 2020, 222: 126-136. PMID: 32882220, PMCID: PMC8328190, DOI: 10.1016/j.ajo.2020.08.038.Peer-Reviewed Original ResearchConceptsED revisitsED visitsOphthalmic careOphthalmic conditionsSingle-institution retrospective cohort studyED revisit ratesIndex ED visitRetrospective cohort studyEmergency department dischargeQuarter of patientsMain outcome measuresTertiary health systemIndex visitCohort studyED presentationsPatients LTFUMultivariable analysisVisual acuityPrimary diagnosisMedical recordsRisk factorsLTFUOutcome measuresPrior historyPatientsClinical efficacy of immunotherapy for the treatment of solid tumors in patients with chronic kidney disease.
Ganta T, Jun T, Qin Q, Patel V, Wang B, Mellgard G, Gogerly-Moragoda M, Leiter A, Gallagher E, Oh W, Galsky M, Tsao C. Clinical efficacy of immunotherapy for the treatment of solid tumors in patients with chronic kidney disease. Journal Of Clinical Oncology 2020, 38: e15109-e15109. DOI: 10.1200/jco.2020.38.15_suppl.e15109.Peer-Reviewed Original ResearchImmune checkpoint inhibitorsChronic kidney diseaseRegulatory T cellsProportion of patientsSolid tumorsT cellsClinical outcomesCancer patients treated with immune checkpoint inhibitorsPatients treated with immune checkpoint inhibitorsEfficacy of immune checkpoint inhibitorsIncidence of renal adverse eventsInhibition of regulatory T cellsTreated with immune checkpoint inhibitorsSingle-institution retrospective cohort studyClinical trialsClinical efficacy of immunotherapyKidney diseaseAssociated with worse clinical outcomesRisk of acute kidney injurySmoking statusPresence of chronic kidney diseasePresence of cardiovascular comorbiditiesTreatment of solid tumorsCancer compared to patientsChronic kidney disease cohort
2018
Sarcomas of the sinonasal tract
Kauke M, Safi A, Grandoch A, Nickenig H, Zöller J, Kreppel M. Sarcomas of the sinonasal tract. Head & Neck 2018, 40: 1279-1286. PMID: 29443431, DOI: 10.1002/hed.25108.Peer-Reviewed Original ResearchConceptsDisease-free survivalSinonasal sarcomaSingle-institution retrospective cohort studyMultimodal therapeutic regimensRetrospective cohort studyOverall survival rateDFS ratesCohort studySinonasal tractTherapeutic regimensMultimodal therapyPrimary tumorDestructive neoplasmSurvival rateSarcomaTherapeutic assessmentSurgeryPrognosisAgeDisease recognitionRegimensPatientsNeoplasmsTherapyNodal
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