2025
Epidemiological Profile and Mortality of Infective Endocarditis Over the Past Decade: A Systematic Review and Meta-Analysis of 133 Studies
Tzoumas A, Sagris M, Xenos D, Ntoumaziou A, Kyriakoulis I, Kakargias F, Liaqat W, Nagraj S, Patel R, Korosoglou G, Tousoulis D, Tsioufis K, Kokkinidis D, Palaiodimos L. Epidemiological Profile and Mortality of Infective Endocarditis Over the Past Decade: A Systematic Review and Meta-Analysis of 133 Studies. The American Journal Of Cardiology 2025, 244: 67-88. PMID: 40015544, DOI: 10.1016/j.amjcard.2025.02.023.Peer-Reviewed Original ResearchInfective endocarditisCausative microorganismsMortality of infective endocarditisEpidemiological profileTricuspid valve IEViridans group streptococciMortality rateRandom-effects model meta-analysisMeta-analysisProfile of IEShort-term mortality rateIncidence of health-careSystematic reviewIncreasingly prevalent conditionGroup streptococciAffected valvePubMed/MEDLINE databaseMitral valveStaphylococcus speciesAortic valveCardiac valvesIncreased incidenceStreptococci speciesEnterococci speciesS. aureus
2024
Comparisons of management approaches in neonatal opioid withdrawal syndrome: The eat, sleep, console approach vs. the Finnegan approach
Johnson K, Berkwitt A, Yankova L, Osborn R. Comparisons of management approaches in neonatal opioid withdrawal syndrome: The eat, sleep, console approach vs. the Finnegan approach. Seminars In Perinatology 2024, 49: 152021. PMID: 39736490, DOI: 10.1016/j.semperi.2024.152021.Peer-Reviewed Original ResearchMood lability and depression limit oral contraceptive therapy in endometriosis
Cevik E, Taylor H. Mood lability and depression limit oral contraceptive therapy in endometriosis. Fertility And Sterility 2024, 123: 838-845. PMID: 39672361, DOI: 10.1016/j.fertnstert.2024.12.011.Peer-Reviewed Original ResearchProgestin-only oral contraceptivesOral contraceptivesOC discontinuationOC useDiagnosis of depressionMood labilityEffects of oral contraceptivesOral contraceptive (OCDocumented diagnosis of depressionDiscontinued OC useEffect of OC useInternational Classification of Diseases-10 codesSide effects of OC useElectronic medical record reviewTreated with OCCourse of treatmentMedical record reviewIncreased incidence of depressionUniversity affiliated hospitalTreatment discontinuationIncidence of depressionEndometriosisStudy cohortPrimary outcomeIncreased incidenceTrends in Invasive Melanoma Thickness in Norway, 1983-2019.
Rimal R, Robsahm T, Green A, Ghiasvand R, Rueegg C, Bassarova A, Gjersvik P, Weiderpass E, Aalen O, Møller B, Perrier F, Veierød M. Trends in Invasive Melanoma Thickness in Norway, 1983-2019. Acta Dermato Venereologica 2024, 104: adv26110. PMID: 39221835, DOI: 10.2340/actadv.v104.26110.Peer-Reviewed Original ResearchConceptsLong-term incidence trendsCancer Registry of NorwayIncidence time trendsTumor thicknessCancer RegistryIncidence trendsBirth cohortTime trendsPrevention strategiesMelanoma occurrenceAge groupsMelanoma RegistryT categoryMelanoma thicknessT1 melanomasPathology reportsYounger patientsAnatomical sitesIncreased incidenceMelanomaSex differencesTumorIncidencePatientsMenClimate Change and Meningoencephalitis in the Americas: A Brewing Storm
Dionne E, Machiavello Roman F, Farhadian S. Climate Change and Meningoencephalitis in the Americas: A Brewing Storm. Current Infectious Disease Reports 2024, 26: 189-196. DOI: 10.1007/s11908-024-00843-x.Peer-Reviewed Original ResearchGeographical distributionImpacts of climate changeEcological interactionsGeographical distribution of vectorsLa Crosse virusVirus infectionVector-borne infectionsNorthward expansionPrecipitation seasonalityClimate changeWest Nile virusPowassan virus infectionCase of meningoencephalitisWarmer wintersPathogensSeasonHuman populationNile virusIncreased incidenceClimate modelsPrecipitation patternsVirusEpidemiological changesMeningoencephalitisDistribution of vectorsGender Differences in Achilles Tendon Ruptures—A Retrospective Study and a Review of the Literature
Hartman H, Cacace A, Leatherman H, Ashkani-Esfahani S, Guss D, Waryasz G, DiGiovanni C, Gianakos A. Gender Differences in Achilles Tendon Ruptures—A Retrospective Study and a Review of the Literature. The Journal Of Foot & Ankle Surgery 2024, 63: 614-620. PMID: 38763172, DOI: 10.1053/j.jfas.2024.04.005.Peer-Reviewed Original ResearchSport involvementPostoperative complicationsAchilles tendon ruptureSystematic reviewRetrospective studyFunctional outcomesRevision surgeryRisk factorsCross-sectional clinical studyRevision rateTendon ruptureSex-specific risk factorsIndependent risk factorPoor functional outcomeSports participationMechanism of injurySystematic literature reviewFemale patientsRetrospective analysisFollow-upClinical studiesInjury managementFemale sexIncreased incidenceLevel IIISurrogate Endpoints in p16-Positive Squamous Cell Carcinoma of the Oropharynx
Gharzai L, Morris E, Nguyen-Tan P, Rosenthal D, Gillison M, Harari P, Garden A, Zanotti K, Caudell J, Jones C, Mitchell D, Krempl G, Ridge J, Gensheimer M, Bonner J, Le Q, Torres-Saavedra P, Mierzwa M, Schipper M. Surrogate Endpoints in p16-Positive Squamous Cell Carcinoma of the Oropharynx. International Journal Of Radiation Oncology • Biology • Physics 2024, 118: e14. DOI: 10.1016/j.ijrobp.2024.01.035.Peer-Reviewed Original ResearchLocoregional progression-free survivalProgression-free survivalP16-positive oropharyngeal cancerOverall survivalOropharyngeal cancerIncreasing incidence of HPV-related cancersIncidence of HPV-related cancersP16-positive squamous cell carcinomaOptimal treatment paradigmMedian Follow-UpHPV-related cancersSquamous cell carcinomaMulticenter randomized trialClinical trial endpointsLocoregional progressionDistant metastasisLocal progressionCell carcinomaDefinitive treatmentTreatment paradigmDMFSFollow-upRandomized trialsIncreased incidenceTreatment effectsLung infections due to emerging fungal pathogens
Roman F, Pischel L, Azar M. Lung infections due to emerging fungal pathogens. Current Opinion In Pulmonary Medicine 2024, 30: 258-265. PMID: 38411158, DOI: 10.1097/mcp.0000000000001059.Peer-Reviewed Original ResearchConceptsEndemic mycosesManagement of pulmonary infectionsFungal pathogensPathogenic fungiAntifungal prophylaxisBlastomyces speciesFungal infectionsFungal organismsAspergillus moldsEnvironmental changesImmunocompromised hostsPulmonary infectionTherapeutic challengeLung infectionMycosesClinical evidenceClinical managementIncreased incidencePulmonary diseaseEnlarged poolDisease burdenInfectionLomentosporaScedosporiumDiagnostic capabilitiesExposome and Metabolome Analysis of Sugarcane Workers Reveals Predictors of Kidney Injury
Stem A, Brindley S, Rogers K, Salih A, Roncal-Jimenez C, Johnson R, Newman L, Butler-Dawson J, Krisher L, Brown J. Exposome and Metabolome Analysis of Sugarcane Workers Reveals Predictors of Kidney Injury. Kidney International Reports 2024, 9: 1458-1472. PMID: 38707825, PMCID: PMC11069010, DOI: 10.1016/j.ekir.2024.01.060.Peer-Reviewed Original ResearchKidney function declineChronic kidney diseaseKidney injuryIncreased incidence of CKDPredictor of kidney injuryKidney diseaseMetabolomic analysisIncidence of chronic kidney diseaseKidney injury marker-1Urine samplesPerturbing amino acid metabolismImpaired kidney functionInvestigate potential biomarkersRates of kidney diseaseUrine profilesKidney functionExposure to silicaIncreased incidencePotential biomarkersAmino acid metabolismUrineOccupational exposure to silicaElemental analysisMetabolomicsFunctional decline
2023
Eradicating Pulmonary Mycobacterium abscessus: The Promise of Dual β-Lactam Therapy
Alahmdi B, Dousa K, Kurz S, Kaufman A, Bonomo R, Taimur S. Eradicating Pulmonary Mycobacterium abscessus: The Promise of Dual β-Lactam Therapy. Open Forum Infectious Diseases 2023, 10: ofad312. PMID: 37383246, PMCID: PMC10296056, DOI: 10.1093/ofid/ofad312.Peer-Reviewed Original Research
2021
Behavioral and neuroanatomical outcomes following altered serotonin expression in a hypoxic-ischemic injury neonate rodent model
Casavant S, Li H, Cong X, Starkweather A, Moore J, Rosenkrantz T, Fitch R. Behavioral and neuroanatomical outcomes following altered serotonin expression in a hypoxic-ischemic injury neonate rodent model. Journal Of Neonatal-Perinatal Medicine 2021, 14: 353-360. PMID: 33164949, DOI: 10.3233/npm-200418.Peer-Reviewed Original ResearchConceptsNeonatal intensive care unitNeonatal rodent modelHypoxic-ischemicSLC6A4 methylationRodent modelsNeuroanatomical outcomesSSRI-treated subjectsWistar rat pupsSerotonin transporter proteinIntensive care unitIncreased incidence of autism spectrum disorderChronic SSRIBehavioral tasksHI injuryHemorrhagic eventsRat pupsIncidence of autism spectrum disordersSerotonin expressionSerotonin levelsPresence of injuryAssociated with methylationSSRIsTreated subjectsSham groupIncreased incidenceHemodynamic and Conduction System Outcomes in Sievers Type 0 and Sievers Type 1 Bicuspid Aortic Valves Post Transcatheter Aortic Valve Replacement
Kumar K, Simpson T, Akhavein R, Rajotte K, Weller S, Fuss C, Song H, Golwala H, Zahr F, Chadderdon S. Hemodynamic and Conduction System Outcomes in Sievers Type 0 and Sievers Type 1 Bicuspid Aortic Valves Post Transcatheter Aortic Valve Replacement. Structural Heart 2021, 5: 287-294. DOI: 10.1080/24748706.2021.1883782.Peer-Reviewed Original ResearchTranscatheter aortic valve replacementSociety of Thoracic SurgeonsBicuspid aortic valveLeft bundle branch blockAortic valve replacementType 1 BAVValve replacementBundle branch blockSelf-expanding prosthesisComputed tomographyPost-TAVRHemodynamic profileAortic valveSuperior hemodynamic profileAortic stenosisParavalvular leakThoracic surgeonsBranch blockIncreased incidenceLeft ventricular outflow tractPost-transcatheter aortic valve replacementValve Academic Research Consortium-2Bicuspid Aortic Valve MorphologyNew York Heart Association classificationLeft ventricular ejection fraction
2020
New-onset intra-operative hyperthermia in a large surgical patient population
Mittnacht A, Lin H, Liu X, Wax D. New-onset intra-operative hyperthermia in a large surgical patient population. European Journal Of Anaesthesiology 2020, 38: 487-493. PMID: 32941199, DOI: 10.1097/eja.0000000000001322.Peer-Reviewed Original ResearchConceptsSurgical Care Improvement ProjectSurgical patient populationPatient populationRisk factorsOverall patient cohortActive patient warmingIntra-operative hypothermiaPrimary outcome measureLogistic regression modelsPaediatric patientsPatient cohortFluid administrationLonger surgeryGeneral anesthesiaIncreased incidenceImprovement projectOutcome measuresSurgeryYounger agePatientsSmall childrenPatient warmingHyperthermiaRegression modelsIncidence
2019
CMV reactivation in allogeneic hematopoietic stem cell transplant patients receiving post-transplant cyclophosphamide.
Markowski P, Schaar D, Wei C, Tyno A. CMV reactivation in allogeneic hematopoietic stem cell transplant patients receiving post-transplant cyclophosphamide. Journal Of Clinical Oncology 2019, 37: e18533-e18533. DOI: 10.1200/jco.2019.37.15_suppl.e18533.Peer-Reviewed Original ResearchPost-transplant cyclophosphamideStem cell transplant patientsCMV reactivationCell transplant patientsPTCy groupTransplant patientsAllogeneic hematopoietic stem cell transplant patientsHematopoietic stem cell transplant patientsReactivation rateDonor CMV serostatusDonor CMV statusPost-transplant CYPrevention of graftEffective prophylactic treatmentNumber of patientsDonor serostatusTransplant cyclophosphamideCMV serostatusHost diseaseCMV statusRetrospective reviewProphylactic treatmentIncreased incidencePatient populationCMV titers
2018
Sex differences in acute kidney injury requiring dialysis
Neugarten J, Golestaneh L, Kolhe N. Sex differences in acute kidney injury requiring dialysis. BMC Nephrology 2018, 19: 131. PMID: 29884141, PMCID: PMC5994053, DOI: 10.1186/s12882-018-0937-y.Peer-Reviewed Original ResearchConceptsAcute kidney injuryKidney injuryFemale sexKidney Disease Improving Global Outcomes Clinical Practice GuidelineHospital-associated acute kidney injuryGlobal Outcomes Clinical Practice GuidelineIncidence of acute kidney injuryRisk of acute kidney injuryAssociated with cardiac surgeryAKI-DHospital-acquired acute kidney injuryPopulation of hospitalized patientsContrast-induced nephropathyRenal replacement therapyHospital Episode Statistics databaseDialysis practiceClinical practice guidelinesAminoglycoside nephrotoxicityCardiac surgeryReplacement therapyPublished cohortMale sexBackgroundFemale sexIncreased incidenceReno-protectionBlood stream infection is associated with cerebrovascular accident in patients with left ventricular assist device: a systematic review and meta-analysis
Kanjanahattakij N, Horn B, Abdulhadi B, Wongjarupong N, Mezue K, Rattanawong P. Blood stream infection is associated with cerebrovascular accident in patients with left ventricular assist device: a systematic review and meta-analysis. Journal Of Artificial Organs 2018, 21: 271-277. PMID: 29546615, DOI: 10.1007/s10047-018-1034-5.Peer-Reviewed Original ResearchConceptsBlood stream infectionsLeft ventricular assist deviceIschemic cerebrovascular accidentCerebrovascular accidentPost-left ventricular assist deviceMeta-analysisAssociated with cerebrovascular accidentsVentricular assist deviceStudy assessed patientsEMBASE electronic databasesHemorrhagic cerebrovascular accidentPooled effect sizeRandom-effects modelInverse of varianceHeart failureIncreased incidenceAssist devicePatientsElectronic databasesSystematic reviewEffect sizeMinimal heterogeneityInfectionBloodMultiple studiesBiomarkers in Heart Failure, Use of
Gandhi P. Biomarkers in Heart Failure, Use of. 2018 DOI: 10.1016/b978-0-12-801238-3.99648-x.Peer-Reviewed Original ResearchBiomarkers in Heart Failure, Use of
Gandhi P. Biomarkers in Heart Failure, Use of. 2018, 293-302. DOI: 10.1016/b978-0-12-809657-4.99648-0.Peer-Reviewed Original Research
2016
AISF position paper on liver transplantation and pregnancy Women in Hepatology Group, Italian Association for the Study of the Liver (AISF)
Alisi A, Balsano C, Bernabucci V, Berzigotti A, Brunetto M, Bugianesi E, Burra P, Calvaruso V, Cariani E, Coco B, Colle I, Critelli R, De Martin E, Del Buono M, Fabregat I, Faillaci F, Fattovich G, Floreani A, Garcia-Tsao G, Housset C, Karampatou A, Lei B, Mangia A, Martinez-Chantar M, Milosa F, Morisco F, Nasta P, Ozben T, Pollicino T, Ponti M, Pontisso P, Reeves H, Rendina M, Rodríguez-Castro K, Sagnelli C, Sebastiani G, Smedile A, Taliani G, Vandelli C, Vanni E, Villa E, Vukotic R, Zignego A, Burra P, Rodríguez-Castro K, Guarino M, Morisco F, Villa E, Mazzella G. AISF position paper on liver transplantation and pregnancy Women in Hepatology Group, Italian Association for the Study of the Liver (AISF). Digestive And Liver Disease 2016, 48: 860-868. PMID: 27267817, DOI: 10.1016/j.dld.2016.04.009.Commentaries, Editorials and LettersConceptsLiver transplant recipientsTransplant recipientsLiver transplantationReproductive ageFemale liver transplant recipientsHypertension/preeclampsiaFoetal growth restrictionFirst successful pregnancyLive birth rateManagement of pregnancyIssue of pregnancyGestational diabetesLiver transplantPreterm deliveryPregnancy outcomesTransplant hepatologistsPediatric patientsSuch patientsPregnancy womenSuccessful pregnancyIncreased incidenceItalian recommendationsSexual functionGrowth restrictionHigh-risk onesDisease prevalence in a rural Andean population of central Peru: a focus on autoimmune and allergic diseases
Caturegli G, Caturegli P. Disease prevalence in a rural Andean population of central Peru: a focus on autoimmune and allergic diseases. Autoimmunity Highlights 2016, 7: 3. PMID: 26861900, PMCID: PMC4749512, DOI: 10.1007/s13317-016-0076-z.Peer-Reviewed Original ResearchAutoimmune diseasesConsecutive clinic daysHygiene hypothesisDisease prevalenceDouble-blind fashionOne-page formPublic health interventionsHealth interventionsBack painClinic daysPhysician notesHashimoto's thyroiditisVision lossVisual disturbancesClinical groundsPrescribed medicationsIncreased incidenceDe-identifiedImaging testsMedical missionsAllergic diseasesRheumatoid arthritisStomach painAmerican physiciansPatients
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