Mark David Siegel, MD
Professor of Medicine (Pulmonary)Cards
About
Titles
Professor of Medicine (Pulmonary)
Program Director, Internal Medicine Traditional Residency Program
Biography
Dr. Siegel graduated from the Columbia University College of Physicians and Surgeons in 1988 and completed his residency in Internal Medicine at the Hospital of the University of Pennsylvania in 1991. He was a Pulmonary & Critical Care fellow at Yale from 1992-95 and has been a full time Yale faculty member since then. Dr. Siegel is Board Certified in Internal Medicine, Pulmonary Medicine, and Critical Care Medicine. He was previously co-chair of the Hospital Bioethics committee. His major clinical focus is in the Intensive Care unit and he attends in the MICU and on the General Internal Medicine services. Dr. Siegel serves on the Editorial Boards of Critical Care Medicine, Chest, and the American Journal of Medicine. He is the recipient of several teaching awards and has participated in several multi-center trials investigating new therapies for the treatment of critical illness. He currently serves as Program Director of the Yale Traditional Internal Medicine Residency.
Appointments
Pulmonary, Critical Care & Sleep Medicine
ProfessorPrimary
Other Departments & Organizations
- Internal Medicine
- Palliative and End-of-Life Care Education
- Program for Biomedical Ethics
- Pulmonary, Critical Care & Sleep Medicine
- Tuberculosis Program
- Winchester Center for Lung Disease
- Yale Medicine
- Yale Ventures
Education & Training
- Fellow
- Yale University School of Medicine (1995)
- Resident
- Hospital of the University of Pennsylvania (1991)
- MD
- College of Physicians & Surgeons, Columbia Univ (1988)
Research
Publications
2024
Takotsubo cardiomyopathy and cardiogenic shock due to hypokalaemic rhabdomyolysis
Hwang E, Namburar S, Siegel M, Sanchez A. Takotsubo cardiomyopathy and cardiogenic shock due to hypokalaemic rhabdomyolysis. BMJ Case Reports 2024, 17: e261456. PMID: 39419603, DOI: 10.1136/bcr-2024-261456.Peer-Reviewed Original ResearchConceptsTakotsubo cardiomyopathyCardiogenic shockAssociated with Takotsubo cardiomyopathyConsistent with cardiogenic shockConsistent with takotsubo cardiomyopathyTriggers of takotsubo cardiomyopathyCentral venous oxygen saturationInfluence cardiac morbidityChronic idiopathic constipationLow central venous oxygen saturationST-segment elevationVenous oxygen saturationWorsening cardiomyopathyGlobal hypokinesisPrognostic significanceCardiac morbidityIdiopathic constipationSpiked helmet signSegment elevationECG patternOxygen saturationCardiomyopathyRhabdomyolysisEchocardiographyEating disorders
2022
Imaging in the Intensive Care Unit
Toy D, Siegel M, Rubinowitz A. Imaging in the Intensive Care Unit. Seminars In Respiratory And Critical Care Medicine 2022, 43: 899-923. PMID: 36442475, DOI: 10.1055/s-0042-1750041.Peer-Reviewed Original ResearchConceptsICU patientsIll patientsPathologic disease statesInterstitial lung diseaseIntensive care unitCT pulmonary angiographySpecific clinical scenariosModality of choicePortable chest radiographsHospital courseRadiologic manifestationsCare unitPleural effusionPulmonary angiographyLung diseaseICU settingChest radiographsSmall pneumothoracesRadiographic examinationAdditional abnormalitiesPatientsClinical scenariosPatient careInvasive devicesDiagnostic accuracy
2021
Reflections on New Evidence on Crisis Standards of Care in the COVID-19 Pandemic.
Tolchin B, Latham SR, Bruce L, Ferrante LE, Kraschel K, Jubanyik K, Hull SC, Herbst JL, Kapo J, Moritz ED, Hughes J, Siegel MD, Mercurio MR. Reflections on New Evidence on Crisis Standards of Care in the COVID-19 Pandemic. The Journal Of Clinical Ethics 2021, 32: 358-360. PMID: 34928864, DOI: 10.1086/jce2021324358.Commentaries, Editorials and LettersConceptsSOFA scoreBlack patientsCrisis standardsSequential Organ Failure Assessment scoreOrgan Failure Assessment scoreAccurate prognostic scoresNext public health emergencyCOVID-19 patientsLife-saving medical resourcesMedical resourcesCOVID-19 pandemicSame scoring systemPublic health emergencyPrognostic scoreBody of evidenceRare casePatientsScoring systemTriage purposesAssessment scoresHealth emergencyCareHealthcare systemCOVID-19ScoresThe Other Side of Triage: When Access to Intensive Care Measures May Do More Harm than Good
Feder KJ, Zaidi D, Siegel MD. The Other Side of Triage: When Access to Intensive Care Measures May Do More Harm than Good. The American Journal Of Bioethics 2021, 21: 79-82. PMID: 34710018, DOI: 10.1080/15265161.2021.1980136.Peer-Reviewed Original ResearchChallenges in interpreting cytokine data in COVID-19 affect patient care and management
Wang SY, Takahashi T, Pine AB, Damsky WE, Simonov M, Zhang Y, Kieras E, Price CC, King BA, Siegel MD, Desir GV, Lee AI, Iwasaki A, Chun HJ. Challenges in interpreting cytokine data in COVID-19 affect patient care and management. PLOS Biology 2021, 19: e3001373. PMID: 34358229, PMCID: PMC8372945, DOI: 10.1371/journal.pbio.3001373.Peer-Reviewed Original Research
2020
Developing a Triage Protocol for the COVID-19 Pandemic: Allocating Scarce Medical Resources in a Public Health Emergency.
Tolchin B, Latham SR, Bruce L, Ferrante LE, Kraschel K, Jubanyik K, Hull SC, Herbst JL, Kapo J, Moritz ED, Hughes J, Siegel MD, Mercurio MR. Developing a Triage Protocol for the COVID-19 Pandemic: Allocating Scarce Medical Resources in a Public Health Emergency. The Journal Of Clinical Ethics 2020, 31: 303-317. PMID: 32991327, DOI: 10.1086/jce2020314303.Peer-Reviewed Original ResearchConceptsPublic health emergencyTriage protocolScarce medical resourcesYale New Haven Health SystemMedical resourcesEthical challengesHealth emergencyCOVID-19 pandemicAllocating Scarce Medical ResourcesFuture wavesMajor ethical challengesChronic comorbiditiesPregnant patientsSimilar public health emergenciesHealthcare workersTriage assessmentClinical judgmentCoronavirus diseaseHealth systemSocioeconomic disparitiesRole of ageCOVID-19Less needPublic discussionSecondary goalMaking Medical Treatment Decisions for Unrepresented Patients in the ICU. An Official American Thoracic Society/American Geriatrics Society Policy Statement
Pope TM, Bennett J, Carson SS, Cederquist L, Cohen AB, DeMartino ES, Godfrey DM, Goodman-Crews P, Kapp MB, Lo B, Magnus DC, Reinke LF, Shirley JL, Siegel MD, Stapleton RD, Sudore RL, Tarzian AJ, Thornton JD, Wicclair MR, Widera EW, White DB. Making Medical Treatment Decisions for Unrepresented Patients in the ICU. An Official American Thoracic Society/American Geriatrics Society Policy Statement. American Journal Of Respiratory And Critical Care Medicine 2020, 201: 1182-1192. PMID: 32412853, PMCID: PMC7233335, DOI: 10.1164/rccm.202003-0512st.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsUnrepresented patientsFair processProcedural due processMedical treatment decisionsPolicy statementsElder lawDue processHealth lawProcedural safeguardsState lawsUndue influenceLawCritical care settingAppropriate balanceAdvance directivesEthical goalsTreatment decisionsAppropriate medical careDiligent searchCapacity assessmentPatient advocacyInstitutionsPolicy recommendationsLess oversightCare settings
2019
A novel approach to the program evaluation committee
Schwartz AR, Siegel MD, Lee AI. A novel approach to the program evaluation committee. BMC Medical Education 2019, 19: 465. PMID: 31842868, PMCID: PMC6916454, DOI: 10.1186/s12909-019-1899-x.Peer-Reviewed Original ResearchConceptsProgram Evaluation CommitteePatient care experiencesResidency programsInternal medicine residency programsNon-medical servicesMedicine residency programsInterdisciplinary carePecs groupActionable feedbackCare experiencesAmbulatory rotationEvaluation CommitteeGraduate Medical EducationInpatientsForm of feedbackOutpatient rotationsAccreditation CouncilStructured group discussionsProgrammatic feedbackEducational curriculumQuality improvementMedical educationFaculty membersFacilitation skillsSurvey assessmentAntibiotics and the Yield of Blood Cultures: Sequence Matters.
Geer JH, Siegel MD. Antibiotics and the Yield of Blood Cultures: Sequence Matters. Annals Of Internal Medicine 2019, 171: 587-588. PMID: 31525773, DOI: 10.7326/m19-2489.Peer-Reviewed Original ResearchThe Unintended Consequences of Hope.
Siegel MD. The Unintended Consequences of Hope. Critical Care Medicine 2019, 47: 1267-1268. PMID: 31415310, DOI: 10.1097/CCM.0000000000003878.Peer-Reviewed Original Research
Academic Achievements & Community Involvement
Clinical Care
Overview
Mark D. Siegel, MD, is a critical care pulmonologist who treats patients with pulmonary embolism, septic shock, acute respiratory distress syndrome, and multiple organ dysfunction syndrome (MODS).
Dr. Siegel also sees patients with asthma, chronic obstructive pulmonary disease (COPD), chronic cough, and bronchiectasis.
“I enjoy caring for patients and families and helping them in moments of crisis,” he says. “I tell my patients that we will do our best to make sure they get the best possible care.”
The challenges of caring for patients with life-threatening conditions led him to specialize in pulmonology.
Dr. Siegel sees patients in the Intensive Care Unit (ICU), the pulmonary consult service at Yale New Haven Hospital, and the Winchester Center for Lung Disease.
Clinical Specialties
Pulmonology & Sleep Medicine; Pulmonary Critical Care
Fact Sheets
Chronic Obstructive Pulmonary Disease (COPD)
Learn More on Yale MedicineAsthma
Learn More on Yale MedicineEndobronchial Valve Placement
Learn More on Yale MedicinePediatric Respiratory Failure
Learn More on Yale Medicine
Board Certifications
Critical Care Medicine (Internal Medicine)
- Certification Organization
- AB of Internal Medicine
- Latest Certification Date
- 2015
- Original Certification Date
- 1995
Pulmonary Disease
- Certification Organization
- AB of Internal Medicine
- Latest Certification Date
- 2014
- Original Certification Date
- 1994
Internal Medicine
- Certification Organization
- AB of Internal Medicine
- Latest Certification Date
- 2012
- Original Certification Date
- 1991
Yale Medicine News
News
News
- March 21, 2025
Match Day 2025: Yale Internal Medicine Welcomes Incoming Residents
- March 16, 2025
Changing the Paradigm
- March 09, 2025
Five Studies (Day 1)
- March 02, 2025
Now It’s Up to the Match Gods
Get In Touch
Contacts
Email
Academic Office Number
Appointment Number
Office Fax Number
Clinic Fax Number
Mailing Address
Pulmonary, Critical Care & Sleep Medicine
PO Box 208057, 300 Cedar Street
New Haven, CT 06520-8057
United States
Administrative Support
Locations
Patient Care Locations
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