2024
A Bayesian incorporated linear non-Gaussian acyclic model for multiple directed graph estimation to study brain emotion circuit development in adolescence
Zhang A, Zhang G, Cai B, Wilson T, Stephen J, Calhoun V, Wang Y. A Bayesian incorporated linear non-Gaussian acyclic model for multiple directed graph estimation to study brain emotion circuit development in adolescence. Network Neuroscience 2024, 8: 791-807. PMID: 39355441, PMCID: PMC11349030, DOI: 10.1162/netn_a_00384.Peer-Reviewed Original ResearchPhiladelphia Neurodevelopmental CohortEmotional circuitryFunctional connectivityBrain's emotional circuitryEmotion identification skillBrain network organizationIndividuals aged 8Emotional processingEmotion perceptionBrain circuitsNeurodevelopmental CohortFMRI dataCognitive developmentIdentification skillsEmotional changesAged 8Adolescent stageAdolescentsNetwork organizationGroup-specific patternsIntermodular connectionsEmotionsCircuit developmentAccurate performanceBrainNeurodevelopmental subtypes of functional brain organization in the ABCD study using a rigorous analytic framework
DeRosa J, Friedman N, Calhoun V, Banich M. Neurodevelopmental subtypes of functional brain organization in the ABCD study using a rigorous analytic framework. NeuroImage 2024, 299: 120827. PMID: 39245397, DOI: 10.1016/j.neuroimage.2024.120827.Peer-Reviewed Original ResearchConceptsResting-state functional connectivityAdolescent Brain Cognitive DevelopmentIndividual’s resting-state functional connectivityAdolescent Brain Cognitive Development StudyFunctional brain organizationMental health profilesMental health characteristicsRsFC dataBrain organizationFunctional connectivityDevelopmental trajectoriesChildren aged 9Emotional functioningCognitive developmentLate childhoodAged 9SubtypesAdolescentsHealth characteristicsHealth profileChildhoodExplainable Multimodal Graph Isomorphism Network for Interpreting Sex Differences in Adolescent Neurodevelopment
Patel B, Orlichenko A, Patel A, Qu G, Wilson T, Stephen J, Calhoun V, Wang Y. Explainable Multimodal Graph Isomorphism Network for Interpreting Sex Differences in Adolescent Neurodevelopment. Applied Sciences 2024, 14: 4144. DOI: 10.3390/app14104144.Peer-Reviewed Original ResearchFunctional magnetic resonance imagingBlood oxygen level-dependentGraph isomorphism networkGraph neural networksBrain networksFunctional magnetic resonance imaging paradigmFunctional magnetic resonance imaging blood oxygen level-dependentSex differencesClassification accuracyExploration of sex differencesInterpreting sex differencesOxygen level-dependentState-of-the-art algorithmsAdolescent neurodevelopmentState-of-the-artNeuropsychiatric conditionsFunctional connectivityTask-related dataDeep learning modelsLevel-dependentMouth movementsFMRI datasetsFunctional networksGraph structureAdolescents
2023
Epigenetic associations with adolescent grey matter maturation and cognitive development
Jensen D, Chen J, Turner J, Stephen J, Wang Y, Wilson T, Calhoun V, Liu J. Epigenetic associations with adolescent grey matter maturation and cognitive development. Frontiers In Genetics 2023, 14: 1222619. PMID: 37529779, PMCID: PMC10390095, DOI: 10.3389/fgene.2023.1222619.Peer-Reviewed Original ResearchGM volume increaseGray matter maturationPatterns of brain maturationImprove cognitive performanceGray matterExecutive functionEpisodic memoryCognitive performanceCognitive testsBrain structuresProcessing speedBrain maturationCognitive AssessmentCognitive scoresBrain imagingAged 9BrainEpigenetic associationsAdolescentsLongitudinal cohortDNA methylationHuman neurodevelopmentDNA methylation of genesCytosine-phosphate-guanine (CpG) sitesBrain tissueFunctional and Structural Longitudinal Change Patterns in Adolescent Brain
Saha R, Saha D, Fu Z, Silva R, Calhoun V. Functional and Structural Longitudinal Change Patterns in Adolescent Brain. Annual International Conference Of The IEEE Engineering In Medicine And Biology Society (EMBC) 2023, 00: 1-4. PMID: 38082649, DOI: 10.1109/embc40787.2023.10340079.Peer-Reviewed Original ResearchConceptsFunctional magnetic resonance imagingStructural magnetic resonance imagingFunctional network connectivityWhole-brainGray matterBrain functional magnetic resonance imagingMagnetic resonance imagingAdolescent brainFunctional connectivityResonance imagingMultivariate patternsLongitudinal change patternsUnivariate changesAdolescentsLongitudinal changesBrainIncreasing ageFunctional changesComplementary techniquesNetwork connectivity