2024
The criminal justice system in alcohol use treatment: a nationwide analysis of racial disparities in treatment referral and completion
Stenersen M, Peltier M, McKee S. The criminal justice system in alcohol use treatment: a nationwide analysis of racial disparities in treatment referral and completion. Alcohol And Alcoholism 2024, 59: agad092. PMID: 38266072, PMCID: PMC10807701, DOI: 10.1093/alcalc/agad092.Peer-Reviewed Original ResearchConceptsCJ systemCriminal justiceCriminal justice systemReferral to alcohol treatmentAnalysis of racial disparitiesInfluence of raceJustice systemTreatment completionNative peopleTreatment Episode Dataset-DischargeImpact of raceCommunities of colorTreatment referralAlcohol treatmentAlcohol use treatmentSubstance useRacial inequalityRacial disparitiesScholarly literatureUse treatmentAmerican Indian/Alaska Native peopleUnited StatesSeries of ANOVAsAlcohol useRaceNavigating Ethical Challenges in Psychological Research Involving Digital Remote Technologies and People Who Use Alcohol or Drugs
Roberts W, McKee S, Miranda R, Barnett N. Navigating Ethical Challenges in Psychological Research Involving Digital Remote Technologies and People Who Use Alcohol or Drugs. American Psychologist 2024, 79: 24-38. PMID: 38236213, PMCID: PMC10798215, DOI: 10.1037/amp0001193.Peer-Reviewed Original ResearchConceptsAmerican Psychological AssociationSubstance use researchPsychological AssociationPsychological researchHealth risk behaviorsBehavioral studiesAlcohol useBehavioral scientistsRisk behaviorsEthical issuesHuman behaviorStandard paradigmComplex ethical issuesInvestigate health risk behaviorsAlcoholAllied fieldsEthical standardsPsychologistsTraditional informed consentDistributive justiceDay-to-day activitiesPsychologyEthical groundsEthical ramificationsSubstances
2022
Using machine learning to predict heavy drinking during outpatient alcohol treatment
Roberts W, Zhao Y, Verplaetse T, Moore KE, Peltier MR, Burke C, Zakiniaeiz Y, McKee S. Using machine learning to predict heavy drinking during outpatient alcohol treatment. Alcohol Clinical And Experimental Research 2022, 46: 657-666. PMID: 35420710, PMCID: PMC9180421, DOI: 10.1111/acer.14802.Peer-Reviewed Original ResearchMeSH KeywordsAlcoholismAlgorithmsEthanolFemaleHumansMachine LearningMaleOutpatientsTreatment OutcomeConceptsAlcohol use disorderHeavy drinkingTreatment outcomesInvasive assessment methodsOutpatient AUD treatmentLast monthOutpatient alcohol treatmentMultisite clinical trialAccurate clinical predictionsHeavy alcohol useSex differencesBi-weekly sessionsAlcohol treatment outcomesPatient characteristicsClinical outcomesClinical trialsClinical dataStratified analysisEffective treatmentPsychiatric disordersUse disordersAUD treatmentSubstantial sex differencesAlcohol treatmentFirst monthSex differences in stress-induced alcohol intake: a review of preclinical studies focused on amygdala and inflammatory pathways
Mineur YS, Garcia-Rivas V, Thomas MA, Soares AR, McKee SA, Picciotto MR. Sex differences in stress-induced alcohol intake: a review of preclinical studies focused on amygdala and inflammatory pathways. Psychopharmacology 2022, 239: 2041-2061. PMID: 35359158, PMCID: PMC9704113, DOI: 10.1007/s00213-022-06120-w.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsAlcohol intakeInflammatory pathwaysAlcohol drinkingStress-induced alcohol drinkingSex differencesSex-dependent effectsStress-induced alcoholEffects of stressPreclinical behavioral modelsAlcohol-dependent behaviorsMicroglial activationClinical studiesPreclinical studiesInflammatory signalingNeuronal functionAlcohol seekingIntakeFuture studiesDrinkingDifferencesAmygdalaPathwayStudyWomen
2017
Effects of varenicline on alcohol cue reactivity in heavy drinkers
Roberts W, Harrison ELR, McKee SA. Effects of varenicline on alcohol cue reactivity in heavy drinkers. Psychopharmacology 2017, 234: 2737-2745. PMID: 28600734, PMCID: PMC5709183, DOI: 10.1007/s00213-017-4667-9.Peer-Reviewed Original ResearchConceptsEffects of vareniclineHuman laboratory studiesAlcohol use disorderAlcohol cue reactivityHeavy drinkersUse disordersPlacebo-controlled human laboratory studyCue exposureAlcohol useCue reactivityUse of vareniclineFront-line treatmentCue-induced alcohol cravingAlcohol cue exposureTitration periodCue-reactivity paradigmMedication groupPharmacological treatmentMedication effectsAdult smokersTobacco cravingVareniclineMethodsAs partLarge seriesAlcohol craving
2016
An overview of alcohol and tobacco/nicotine interactions in the human laboratory
Verplaetse TL, McKee SA. An overview of alcohol and tobacco/nicotine interactions in the human laboratory. The American Journal Of Drug And Alcohol Abuse 2016, 43: 186-196. PMID: 27439453, PMCID: PMC5588903, DOI: 10.1080/00952990.2016.1189927.Peer-Reviewed Original ResearchConceptsAlcohol-tobacco interactionsNicotine interactionsHuman laboratorySubjective responsesBlood alcohol curveDrinking cuesAlcohol use disorderOverview of alcoholNicotine deprivationSelf-administration behaviorDrugs of abuseAlcohol cravingReciprocal influenceAlcohol curveAlcohol influenceSubjective effectsUse disordersTobacco/nicotineNicotine administrationTobacco useInteractive effectsCravingMajor public health concernPublic health concernDrinkersEffect of Varenicline Combined with High‐Dose Alcohol on Craving, Subjective Intoxication, Perceptual Motor Response, and Executive Cognitive Function in Adults with Alcohol Use Disorders: Preliminary Findings
Verplaetse TL, Pittman BP, Shi JM, Tetrault JM, Coppola S, McKee SA. Effect of Varenicline Combined with High‐Dose Alcohol on Craving, Subjective Intoxication, Perceptual Motor Response, and Executive Cognitive Function in Adults with Alcohol Use Disorders: Preliminary Findings. Alcohol Clinical And Experimental Research 2016, 40: 1567-1576. PMID: 27246567, PMCID: PMC4930423, DOI: 10.1111/acer.13110.Peer-Reviewed Original ResearchMeSH KeywordsAdultAlcohol-Related DisordersAlcoholic IntoxicationAssociation LearningBlood PressureCravingDose-Response Relationship, DrugDouble-Blind MethodEthanolExecutive FunctionFemaleHeart RateHumansMaleMemory, Short-TermNicotinic AgonistsPsychological TestsPsychomotor PerformanceVareniclineYoung AdultConceptsPerceptual-motor functionAlcohol use disorderExecutive cognitive functionCognitive functionDose of alcoholSubjective reactivitySubjective intoxicationHigh-dose alcoholNonalcoholic control beverageAlcohol-motivated behaviorsUse disordersEffects of vareniclineAssociative learningAversive eventsLaboratory paradigmDiastolic blood pressureAlcohol cravingControl beverageMotor responsePhysiologic reactivityAlcohol-related increasesLaboratory sessionsMotor functionBlood pressurePreliminary investigation
2014
Acute effects of low and high dose alcohol on smoking lapse behavior in a laboratory analogue task
Kahler CW, Metrik J, Spillane NS, Day A, Leventhal AM, McKee SA, Tidey JW, McGeary JE, Knopik VS, Rohsenow DJ. Acute effects of low and high dose alcohol on smoking lapse behavior in a laboratory analogue task. Psychopharmacology 2014, 231: 4649-4657. PMID: 24858377, PMCID: PMC4232980, DOI: 10.1007/s00213-014-3613-3.Peer-Reviewed Original ResearchConceptsHigh-dose alcoholAlcohol consumptionAcute smoking abstinenceLaboratory analogue taskHeavy alcohol drinkersLow-dose alcoholDose-response effectDose-dependent fashionDose-dependent effectEffect of doseAlcohol drinkersSmoking abstinenceAcute effectsPlacebo beverageSmoking behaviorSmoking urgesSmokingEffect of LowSeparate daysGreater riskLapse behaviorAlcohol effectsPlaceboAbstinenceAlcohol lead
2012
Sex differences in stimulus expectancy and pharmacologic effects of a moderate dose of alcohol on smoking lapse risk in a laboratory analogue study
Kahler CW, Metrik J, Spillane NS, Leventhal AM, McKee SA, Tidey JW, McGeary JE, Knopik VS, Rohsenow DJ. Sex differences in stimulus expectancy and pharmacologic effects of a moderate dose of alcohol on smoking lapse risk in a laboratory analogue study. Psychopharmacology 2012, 222: 71-80. PMID: 22227611, PMCID: PMC3687530, DOI: 10.1007/s00213-011-2624-6.Peer-Reviewed Original ResearchConceptsInstruction conditionPharmacologic effectsStimulus expectancyQuit smoking attemptsDirect pharmacologic effectInitial lapseHeavy alcohol drinkersLapse riskLaboratory analog studiesPlacebo designBeverage contentSmoking attemptsAnalogue studyAlcohol drinkersGreater satisfactionModerate doseSex differencesSmoking behaviorPharmacological effectsSmokingNonalcoholic beveragesTaskCondition effectsSatisfactionInstruction
2011
Preliminary Findings on the Interactive Effects of IV Ethanol and IV Nicotine on Human Behavior and Cognition: A Laboratory Study
Ralevski E, Perry EB, D’Souza D, Bufis V, Elander J, Limoncelli D, Vendetti M, Dean E, Cooper TB, McKee S, Petrakis I. Preliminary Findings on the Interactive Effects of IV Ethanol and IV Nicotine on Human Behavior and Cognition: A Laboratory Study. Nicotine & Tobacco Research 2011, 14: 596-606. PMID: 22180582, PMCID: PMC6281082, DOI: 10.1093/ntr/ntr258.Peer-Reviewed Original ResearchConceptsRey Auditory Verbal Learning TaskAuditory Verbal Learning TaskVerbal learning taskAcute intravenous alcoholSubjective alcohol effectsBiphasic Alcohol Effects ScaleAlcohol-induced deficitsAlcohol-induced impairmentDoses of alcoholActive nicotineInteractive effectsTest dayCognitive inhibitionVerbal learningCognitive performanceLearning taskSubjective intoxicationAlcohol effectsHuman behaviorNicotine effectsIntravenous alcoholAlcohol infusionManner oneSubjective effectsCognition
2009
Varenicline Reduces Alcohol Self-Administration in Heavy-Drinking Smokers
McKee SA, Harrison EL, O'Malley SS, Krishnan-Sarin S, Shi J, Tetrault JM, Picciotto MR, Petrakis IL, Estevez N, Balchunas E. Varenicline Reduces Alcohol Self-Administration in Heavy-Drinking Smokers. Biological Psychiatry 2009, 66: 185-190. PMID: 19249750, PMCID: PMC2863311, DOI: 10.1016/j.biopsych.2009.01.029.Peer-Reviewed Original ResearchConceptsHeavy drinking smokersSelf-administration periodAlcohol consumptionPartial nicotinic agonistPlacebo-controlled investigationEffects of vareniclineReduced ethanol intakeAlcohol Self-AdministrationAlcohol use disorderNicotinic acetylcholine receptorsMedication pretreatmentAdverse eventsNumber of drinksPreclinical evidenceAdditional drinkEthanol intakeTobacco dependenceDaily smokersPriming doseVareniclineComorbid disordersNicotinic agonistsUse disordersPriming drinkPotential treatment
2008
Nondaily Smoking and Alcohol Use, Hazardous Drinking, and Alcohol Diagnoses Among Young Adults: Findings From the NESARC
Harrison EL, Desai RA, McKee SA. Nondaily Smoking and Alcohol Use, Hazardous Drinking, and Alcohol Diagnoses Among Young Adults: Findings From the NESARC. Alcohol Clinical And Experimental Research 2008, 32: 2081-2087. PMID: 18828805, PMCID: PMC2626157, DOI: 10.1111/j.1530-0277.2008.00796.x.Peer-Reviewed Original ResearchConceptsAlcohol use disorderDSM-IV alcohol diagnosesHazardous drinkingDaily smokersUse disordersAlcohol useYoung adultsNondaily smokersAlcohol diagnosisDaily binge drinkingCigarette use patternsNational Epidemiologic SurveyCurrent smoking behaviorDrinking behaviorHeavy alcohol useAlcohol use patternsCurrent smokersBinge drinking behaviorSmoking statusDaily smokingNondaily smokingCurrent drinkersMultinomial logistic regressionBinge drinkingSmokers
2007
Young adult non-daily smokers: Patterns of alcohol and cigarette use
Harrison EL, McKee SA. Young adult non-daily smokers: Patterns of alcohol and cigarette use. Addictive Behaviors 2007, 33: 668-674. PMID: 18093745, PMCID: PMC2349092, DOI: 10.1016/j.addbeh.2007.11.012.Peer-Reviewed Original Research
2006
Modeling the effect of alcohol on smoking lapse behavior
McKee SA, Krishnan-Sarin S, Shi J, Mase T, O’Malley S. Modeling the effect of alcohol on smoking lapse behavior. Psychopharmacology 2006, 189: 201-210. PMID: 17013640, PMCID: PMC2862311, DOI: 10.1007/s00213-006-0551-8.Peer-Reviewed Original ResearchConceptsFirst cigaretteSelf-administration sessionsNovel human laboratory modelPoor smoking cessation outcomesSmoking cessation outcomesSmoking lapse behaviorHuman laboratory modelEffects of alcoholSecondary outcomesAlcohol drinkersLapse behaviorMore cigarettesNicotine withdrawalCessation outcomesRisk factorsDaily smokersSubsequent smokingTobacco cravingPlacebo beverageTobacco relapseSmoking sessionHeavy social drinkersPriming drinkAlcohol consumptionAlcohol use