2022
Intervention Fidelity in Pain Pragmatic Trials for Nonpharmacologic Pain Management: Nuanced Considerations for Determining PRECIS-2 Flexibility in Delivery and Adherence
Kerns R, Davis A, Fritz J, Keefe F, Peduzzi P, Rhon D, Taylor S, Vining R, Yu Q, Zeliadt S, George S. Intervention Fidelity in Pain Pragmatic Trials for Nonpharmacologic Pain Management: Nuanced Considerations for Determining PRECIS-2 Flexibility in Delivery and Adherence. Journal Of Pain 2022, 24: 568-574. PMID: 36574858, PMCID: PMC10079571, DOI: 10.1016/j.jpain.2022.12.008.Peer-Reviewed Original ResearchConceptsPragmatic clinical trialsDelivery of interventionsClinical trialsNonpharmacologic pain managementPain management strategiesRoutine clinical settingPain managementNonpharmacological treatmentsRoutine careNonpharmacological interventionsPragmatic trialIntervention core componentsProvider trainingReal-world settingClinical settingIntervention fidelityTreatment flexibilityTrialsInterventionTreatment effectsDegree of pragmatismImplementation barriersAdherenceIntervention monitoringDelivery
2008
A randomized clinical trial for women with vulvodynia: Cognitive-behavioral therapy vs. supportive psychotherapy
Masheb RM, Kerns RD, Lozano C, Minkin MJ, Richman S. A randomized clinical trial for women with vulvodynia: Cognitive-behavioral therapy vs. supportive psychotherapy. Pain 2008, 141: 31-40. PMID: 19022580, PMCID: PMC2728361, DOI: 10.1016/j.pain.2008.09.031.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapySupportive psychotherapyPain severityRandomized clinical trialsOne-year followGreater patient satisfactionGreater improvementSelf-management skillsClinical improvementPatient satisfactionPhysician examinationSexual functionMixed-effects modelingClinical trialsPsychosocial treatmentsBetter outcomesTreatment approachesVulvodyniaCBT conditionTreatment improvementOne-yearRelative efficacySignificant decreaseTreatment effectsWomen