2023
Research objectives and general considerations for pragmatic clinical trials of pain treatments: IMMPACT statement
Hohenschurz-Schmidt D, Cherkin D, Rice A, Dworkin R, Turk D, McDermott M, Bair M, DeBar L, Edwards R, Farrar J, Kerns R, Markman J, Rowbotham M, Sherman K, Wasan A, Cowan P, Desjardins P, Ferguson M, Freeman R, Gewandter J, Gilron I, Grol-Prokopczyk H, Hertz S, Iyengar S, Kamp C, Karp B, Kleykamp B, Loeser J, Mackey S, Malamut R, McNicol E, Patel K, Sandbrink F, Schmader K, Simon L, Steiner D, Veasley C, Vollert J. Research objectives and general considerations for pragmatic clinical trials of pain treatments: IMMPACT statement. Pain 2023, 164: 1457-1472. PMID: 36943273, PMCID: PMC10281023, DOI: 10.1097/j.pain.0000000000002888.Peer-Reviewed Original ResearchConceptsPragmatic trialPain treatmentClinical careSystematic reviewAddiction Clinical Trial TranslationsNetworks (ACTTION) public-private partnershipTraditional efficacy trialsRoutine clinical careDaily clinical carePragmatic clinical trialsEvidence-based treatmentsRelated health policiesInternal validityPain assessmentClinical managementClinical trialsEfficacy trialsConsensus meetingTrial designConsensus discussionTrial objectivesSuch trialsHealth policyTrialsExpert presentations
2020
Trajectories of Self-Reported Opioid Use Among Patients With HIV Engaged in Care: Results From a National Cohort Study.
Edelman EJ, Li Y, Barry D, Brennan Braden J, Crystal S, Kerns RD, Gaither JR, Gordon KS, Manhapra A, Merlin JS, Moore BA, Oldfield BJ, Park LS, Rentsch CT, Skanderson M, Williams EC, Justice AC, Tate JP, Becker WC, Marshall BDL. Trajectories of Self-Reported Opioid Use Among Patients With HIV Engaged in Care: Results From a National Cohort Study. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2020, 84: 26-36. PMID: 32267658, PMCID: PMC7147724, DOI: 10.1097/qai.0000000000002310.Peer-Reviewed Original ResearchConceptsOpioid useOpioid use trajectoriesCohort studyPain interferenceSelf-reported opioid useVeterans Aging Cohort StudyVeterans Health Administration sitesInfrequent useOpioid use frequencyMarijuana useAging Cohort StudyNational cohort studyEvidence-based treatmentsGroup-based trajectory modelsProspective cohortBaseline factorsIllness severityMultivariable analysisBenzodiazepine medicationVA carePsychoactive medicationsPrescription painkillersPsychiatric symptomsHeroin useMultinomial logistic regression
2017
Interactive Voice Response–Based Self-management for Chronic Back Pain: The COPES Noninferiority Randomized Trial
Heapy AA, Higgins DM, Goulet JL, LaChappelle KM, Driscoll MA, Czlapinski RA, Buta E, Piette JD, Krein SL, Kerns RD. Interactive Voice Response–Based Self-management for Chronic Back Pain: The COPES Noninferiority Randomized Trial. JAMA Internal Medicine 2017, 177: 765-773. PMID: 28384682, PMCID: PMC5818820, DOI: 10.1001/jamainternmed.2017.0223.Peer-Reviewed Original ResearchConceptsPerson cognitive-behavioural therapyChronic back painNumeric rating scaleCognitive behavioral therapyBack painChronic painPrimary outcomeSleep qualityVeterans Affairs Health Care SystemPrespecified noninferiority marginAverage pain intensityNonpharmacologic treatment optionsPain-related interferenceChronic pain treatmentSelf-management trialCognitive behavioral therapy deliveryIndividual CBT sessionsEvidence-based treatmentsQuality of lifeSelf-help manualHealth care systemIVR monitoringNonpharmacologic interventionsSecondary outcomesStandard therapy
2016
Cooperative pain education and self-management (COPES): study design and protocol of a randomized non-inferiority trial of an interactive voice response-based self-management intervention for chronic low back pain
Heapy AA, Higgins DM, LaChappelle KM, Kirlin J, Goulet JL, Czlapinski RA, Buta E, Piette JD, Krein SL, Richardson CR, Kerns RD. Cooperative pain education and self-management (COPES): study design and protocol of a randomized non-inferiority trial of an interactive voice response-based self-management intervention for chronic low back pain. BMC Musculoskeletal Disorders 2016, 17: 85. PMID: 26879051, PMCID: PMC4754867, DOI: 10.1186/s12891-016-0924-z.Peer-Reviewed Original ResearchConceptsChronic low back painLow back painNon-inferiority trialRandomized non-inferiority trialCognitive behavioral therapyPerson cognitive-behavioural therapyBack painClinical outcomesChronic pain conditionsNumeric rating scalePain-related interferencePatient-reported informationSelf-management interventionsEvidence-based treatmentsQuality of lifeUS military veteransStatewide health systemBackgroundThe InstituteIVR monitoringSecondary outcomesMore patientsPain conditionsPain intensityPrimary outcomeChronic pain
2011
Complicating Factors Associated with Mild Traumatic Brain Injury: Impact on Pain and Posttraumatic Stress Disorder Treatment
Otis JD, McGlinchey R, Vasterling JJ, Kerns RD. Complicating Factors Associated with Mild Traumatic Brain Injury: Impact on Pain and Posttraumatic Stress Disorder Treatment. Journal Of Clinical Psychology In Medical Settings 2011, 18: 145-154. PMID: 21626354, DOI: 10.1007/s10880-011-9239-2.Peer-Reviewed Original ResearchMeSH KeywordsAfghan Campaign 2001-Brain ConcussionChronic DiseaseCombat DisordersCombined Modality TherapyComorbidityCooperative BehaviorHumansInterdisciplinary CommunicationIraq War, 2003-2011Military PersonnelMultiple TraumaOutcome and Process Assessment, Health CarePainPatient Care TeamPsychotherapyStress Disorders, Post-TraumaticVeteransConceptsPosttraumatic stress disorderOEF/OIF veteransMild traumatic brain injuryOIF veteransPsychological treatmentTraumatic brain injuryEvidence-based psychological treatmentsPosttraumatic stress disorder (PTSD) treatmentBrain injuryEvidence-based treatmentsChronic painStress disorderNeeds of individualsOperation Enduring FreedomComorbidity of painNature of combatDisorder treatmentEnduring FreedomIraqi FreedomVeteransTreatment approachesMultidisciplinary treatment approachSymptomatologyPainComorbidities