2013
Differentiating Patterns of Amygdala-Frontal Functional Connectivity in Schizophrenia and Bipolar Disorder
Liu H, Tang Y, Womer F, Fan G, Lu T, Driesen N, Ren L, Wang Y, He Y, Blumberg HP, Xu K, Wang F. Differentiating Patterns of Amygdala-Frontal Functional Connectivity in Schizophrenia and Bipolar Disorder. Schizophrenia Bulletin 2013, 40: 469-477. PMID: 23599250, PMCID: PMC3932086, DOI: 10.1093/schbul/sbt044.Peer-Reviewed Original ResearchConceptsResting-state functional connectivityBipolar disorderBD groupPrefrontal cortexHealthy controlsFunctional connectivityResting-state functional magnetic resonance imagingNeural system abnormalitiesDorsal lateral prefrontal cortexFunctional magnetic resonance imagingMagnetic resonance imagingVentral prefrontal cortexClinical characteristicsSystem abnormalitiesSuperficial amygdalaAnatomic mapAmygdala subregionsHC groupResonance imagingLateral prefrontal cortexAmygdalaSZ groupSchizophreniaDisordersSignificant differences
2009
Behavioral and neural correlates of memory selection and interference resolution during a digit working memory task
Yi Y, Driesen N, Leung HC. Behavioral and neural correlates of memory selection and interference resolution during a digit working memory task. Cognitive, Affective, & Behavioral Neuroscience 2009, 9: 249-259. PMID: 19679761, PMCID: PMC2741611, DOI: 10.3758/cabn.9.3.249.Peer-Reviewed Original ResearchConceptsProactive interferenceMemory selectionNeural correlatesEffects of PILeft inferior parietal lobePrefrontal-parietal networkStrong proactive interferenceTask-relevant informationInferior parietal lobeResponse time differencesMiddle frontal gyrusPosterior parietal cortexInterference resolutionMemory taskFrontal gyrusRecognition taskRelevant digitsSelection cuesDelay intervalPrecue intervalsParietal cortexInformation processingParietal lobeTaskCorrelates
2008
Impairment of Working Memory Maintenance and Response in Schizophrenia: Functional Magnetic Resonance Imaging Evidence
Driesen NR, Leung HC, Calhoun VD, Constable RT, Gueorguieva R, Hoffman R, Skudlarski P, Goldman-Rakic PS, Krystal JH. Impairment of Working Memory Maintenance and Response in Schizophrenia: Functional Magnetic Resonance Imaging Evidence. Biological Psychiatry 2008, 64: 1026-1034. PMID: 18823880, PMCID: PMC2650279, DOI: 10.1016/j.biopsych.2008.07.029.Peer-Reviewed Original ResearchConceptsMemory taskPrefrontal activityMemory maintenanceBrain activationFunctional Magnetic Resonance Imaging EvidenceWorking Memory MaintenanceCognitive impairmentHealthy comparison participantsPrefrontal cortical activityFunctional magnetic resonanceMemory loadComparison participantsTask accuracyDistinct neurobiologyCortical activityHealthy participantsBasic research insightsImaging EvidenceMemoryCortical deficitsCortical functionPoor performanceTaskSchizophreniaResponse phase
2006
Brain Connectivity Related to Working Memory Performance
Hampson M, Driesen NR, Skudlarski P, Gore JC, Constable RT. Brain Connectivity Related to Working Memory Performance. Journal Of Neuroscience 2006, 26: 13338-13343. PMID: 17182784, PMCID: PMC2677699, DOI: 10.1523/jneurosci.3408-06.2006.Peer-Reviewed Original ResearchConceptsPosterior cingulate cortexMemory taskCognitive tasksCingulate cortexVentral anterior cingulate cortexDifferent cognitive tasksMedial frontal regionsMedial frontal gyrusDefault mode networkAnterior cingulate cortexFunctional imaging studiesCognitive abilitiesIndividual differencesMemory performanceCognitive performanceFrontal gyrusMode networkFrontal regionsFunctional connectivityBrain connectivityBrain areasTaskFunctional connectionsImaging studiesCortex
1995
Selective neuroanatomic abnormalities in Down's syndrome and their cognitive correlates: evidence from MRI morphometry.
Raz N, Torres I, Briggs S, Spencer W, Thornton A, Loken W, Gunning F, McQuain J, Driesen N, Acker J. Selective neuroanatomic abnormalities in Down's syndrome and their cognitive correlates: evidence from MRI morphometry. Neurology 1995, 45: 356-66. PMID: 7854539, DOI: 10.1212/wnl.45.2.356.Peer-Reviewed Original ResearchConceptsDS subjectsDown syndromeNeuroanatomic abnormalitiesParahippocampal gyrusWhite matterBrain regionsSex-matched healthy volunteersDisease hypothesisAnterior cingulate gyrusParietal white matterPrefrontal white matterPremature agingDorsolateral prefrontal cortexCerebral damageThyroid dysfunctionAge-related declineSeizure disorderSignificant group differencesBasal gangliaBrain abnormalitiesCardiovascular diseaseMammillary bodiesCerebellar hemispherePostcentral gyrusCingulate gyrus
1994
Individual Differences in Neurobehavioral Disruption During Mild and Moderate Hypoglycemia in Adults With IDDM
Gonder-Frederick L, Cox D, Driesen N, Ryan C, Clarke W. Individual Differences in Neurobehavioral Disruption During Mild and Moderate Hypoglycemia in Adults With IDDM. Diabetes 1994, 43: 1407-1412. PMID: 7958491, DOI: 10.2337/diab.43.12.1407.Peer-Reviewed Original ResearchConceptsInsulin-dependent diabetes mellitusModerate hypoglycemiaDegree of impairmentHistory of unconsciousnessNeurobehavioral deteriorationDiabetes mellitusGlycemic thresholdsTest four timesMild hypoglycemiaDay protocolNeurobehavioral disruptionNeurobehavioral effectsGlycemic recoveryHypoglycemiaMore deteriorationRepeat testingCrossover designControl dayDeterioration scoresConsecutive daysExperimental daysImpairment
1993
Malignant peripheral nerve sheath tumors. A clinicopathologic study of 28 cases
Wanebo J, Malik J, Vandenberg S, Wanebo H, Driesen N, Persing J. Malignant peripheral nerve sheath tumors. A clinicopathologic study of 28 cases. Cancer 1993, 71: 1247-1253. PMID: 8435801, DOI: 10.1002/1097-0142(19930215)71:4<1247::aid-cncr2820710413>3.0.co;2-s.Peer-Reviewed Original ResearchConceptsMalignant peripheral nerve sheath tumorDisease-free survivalSurgical marginsTumor sizeTumor locationSurvival timeMedian disease-free survival timeBetter disease-free survivalMedian overall survival timePeripheral nerve sheath tumorsDisease-free survival timeVirginia Health Sciences CenterAdjuvant radiation therapyExtent of surgeryWide surgical marginsNerve sheath tumorsOverall survival timeQuality of marginsNeurofibromatosis type 1Type of treatmentHealth Sciences CenterAggressive surgeryClinicopathologic studyOverall survivalPatient age