2013
Differentiating Patterns of Amygdala-Frontal Functional Connectivity in Schizophrenia and Bipolar Disorder
Liu H, Tang Y, Womer F, Fan G, Lu T, Driesen N, Ren L, Wang Y, He Y, Blumberg HP, Xu K, Wang F. Differentiating Patterns of Amygdala-Frontal Functional Connectivity in Schizophrenia and Bipolar Disorder. Schizophrenia Bulletin 2013, 40: 469-477. PMID: 23599250, PMCID: PMC3932086, DOI: 10.1093/schbul/sbt044.Peer-Reviewed Original ResearchMeSH KeywordsAdultAmygdalaBipolar DisorderConnectomeFemaleHumansMagnetic Resonance ImagingMalePrefrontal CortexSchizophreniaConceptsResting-state functional connectivityBipolar disorderBD groupPrefrontal cortexHealthy controlsFunctional connectivityResting-state functional magnetic resonance imagingNeural system abnormalitiesDorsal lateral prefrontal cortexFunctional magnetic resonance imagingMagnetic resonance imagingVentral prefrontal cortexClinical characteristicsSystem abnormalitiesSuperficial amygdalaAnatomic mapAmygdala subregionsHC groupResonance imagingLateral prefrontal cortexAmygdalaSZ groupSchizophreniaDisordersSignificant differences
2009
Behavioral and neural correlates of memory selection and interference resolution during a digit working memory task
Yi Y, Driesen N, Leung HC. Behavioral and neural correlates of memory selection and interference resolution during a digit working memory task. Cognitive, Affective, & Behavioral Neuroscience 2009, 9: 249-259. PMID: 19679761, PMCID: PMC2741611, DOI: 10.3758/cabn.9.3.249.Peer-Reviewed Original ResearchConceptsProactive interferenceMemory selectionNeural correlatesEffects of PILeft inferior parietal lobePrefrontal-parietal networkStrong proactive interferenceTask-relevant informationInferior parietal lobeResponse time differencesMiddle frontal gyrusPosterior parietal cortexInterference resolutionMemory taskFrontal gyrusRecognition taskRelevant digitsSelection cuesDelay intervalPrecue intervalsParietal cortexInformation processingParietal lobeTaskCorrelates
2008
Impairment of Working Memory Maintenance and Response in Schizophrenia: Functional Magnetic Resonance Imaging Evidence
Driesen NR, Leung HC, Calhoun VD, Constable RT, Gueorguieva R, Hoffman R, Skudlarski P, Goldman-Rakic PS, Krystal JH. Impairment of Working Memory Maintenance and Response in Schizophrenia: Functional Magnetic Resonance Imaging Evidence. Biological Psychiatry 2008, 64: 1026-1034. PMID: 18823880, PMCID: PMC2650279, DOI: 10.1016/j.biopsych.2008.07.029.Peer-Reviewed Original ResearchConceptsMemory taskPrefrontal activityMemory maintenanceBrain activationFunctional Magnetic Resonance Imaging EvidenceWorking Memory MaintenanceCognitive impairmentHealthy comparison participantsPrefrontal cortical activityFunctional magnetic resonanceMemory loadComparison participantsTask accuracyDistinct neurobiologyCortical activityHealthy participantsBasic research insightsImaging EvidenceMemoryCortical deficitsCortical functionPoor performanceTaskSchizophreniaResponse phase
2006
Hypoglycemia reduces the blood‐oxygenation level dependent signal in primary auditory and visual cortex: A functional magnetic resonance imaging study
Driesen NR, Goldberg PA, Anderson AW, Tang L, Flanagan DE, Sherwin RS, Gore JC. Hypoglycemia reduces the blood‐oxygenation level dependent signal in primary auditory and visual cortex: A functional magnetic resonance imaging study. Journal Of Neuroscience Research 2006, 85: 575-582. PMID: 17154420, DOI: 10.1002/jnr.21146.Peer-Reviewed Original ResearchConceptsMagnetic resonance imagingFunctional magnetic resonance imagingModerate hypoglycemiaVisual cortexResonance imagingCentral nervous system effectsMagnetic resonance imaging studyNon-diabetic controlsNon-diabetic participantsNervous system effectsBlood oxygenation level-dependent (BOLD) signalFrequent hypoglycemic episodesBlood oxygenation level-dependent (BOLD) responseEffects of hypoglycemiaResonance imaging studyFunctional magnetic resonance imaging studyLevel-dependent signalLevel-dependent responsesVisual stimuliHypoglycemic episodesT1DM patientsPrimary auditoryEuglycemic periodHypoglycemic responseNeurophysiologic changes
1995
Selective neuroanatomic abnormalities in Down's syndrome and their cognitive correlates: evidence from MRI morphometry.
Raz N, Torres I, Briggs S, Spencer W, Thornton A, Loken W, Gunning F, McQuain J, Driesen N, Acker J. Selective neuroanatomic abnormalities in Down's syndrome and their cognitive correlates: evidence from MRI morphometry. Neurology 1995, 45: 356-66. PMID: 7854539, DOI: 10.1212/wnl.45.2.356.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnalysis of VarianceBrainCognitionDown SyndromeFemaleHumansIntelligenceIntelligence TestsLanguageMagnetic Resonance ImagingMaleOrgan SpecificityReference ValuesConceptsDS subjectsDown syndromeNeuroanatomic abnormalitiesParahippocampal gyrusWhite matterBrain regionsSex-matched healthy volunteersDisease hypothesisAnterior cingulate gyrusParietal white matterPrefrontal white matterPremature agingDorsolateral prefrontal cortexCerebral damageThyroid dysfunctionAge-related declineSeizure disorderSignificant group differencesBasal gangliaBrain abnormalitiesCardiovascular diseaseMammillary bodiesCerebellar hemispherePostcentral gyrusCingulate gyrus