2024
The combination of donepezil and cognitive training for improving treatment outcomes for alcohol use disorder: Design of a randomized controlled trial
Yoon G, Sofuoglu M, Petrakis I, Pittman B, Bell M. The combination of donepezil and cognitive training for improving treatment outcomes for alcohol use disorder: Design of a randomized controlled trial. Contemporary Clinical Trials 2024, 145: 107657. PMID: 39111388, PMCID: PMC11423257, DOI: 10.1016/j.cct.2024.107657.Peer-Reviewed Original ResearchCognitive remediation therapyAlcohol use disorderAlcohol use disorder treatment outcomesNeurocognitive functionCombination of donepezilRemediation therapyUse disorderTreatment outcomesDevelopment of alcohol use disordersReduce heavy drinking daysHeavy drinking daysGlobal neurocognitive functioningImprove neurocognitive functionEnhanced neurocognitive functionImprove cognitive functionRandomized controlled trialsReduce alcohol consumptionNeurobiological evidenceDrinking daysNeurocognitive function scoresCognitive trainingVA Connecticut Healthcare SystemCognitive functionImprove treatment outcomesCognitive impairment
2017
A Randomized Controlled Trial of Cognitive Remediation and Work Therapy in the Early Phase of Substance Use Disorder Recovery for Older Veterans: Neurocognitive and Substance Use Outcomes
Bell MD, Laws HB, Petrakis IB. A Randomized Controlled Trial of Cognitive Remediation and Work Therapy in the Early Phase of Substance Use Disorder Recovery for Older Veterans: Neurocognitive and Substance Use Outcomes. Psychiatric Rehabilitation Journal 2017, 40: 94-102. PMID: 27732034, PMCID: PMC5378626, DOI: 10.1037/prj0000211.Peer-Reviewed Original ResearchConceptsCognitive remediation therapyWork therapySUD outcomesExecutive Function IndexOutpatient veteransSubstance use disorder outcomesDays of abstinenceExecutive functionPremorbid IQCognitive changesCognitive recoveryPilot study reportsDisorder outcomesResidential treatmentSubstance useCognitive impairmentDrug abuseBaseline assessmentTotal abstinenceMixed effects modelsAbstinenceVeteransOutpatient treatmentSUDBlind assessment