Featured Publications
Role of Exogenous Progesterone in the Treatment of Men and Women with Substance Use Disorders: A Narrative Review
Peltier MR, Sofuoglu M. Role of Exogenous Progesterone in the Treatment of Men and Women with Substance Use Disorders: A Narrative Review. CNS Drugs 2018, 32: 421-435. PMID: 29761343, PMCID: PMC6235727, DOI: 10.1007/s40263-018-0525-5.Peer-Reviewed Original ResearchConceptsSubstance use disordersExogenous progesteroneUse disordersTreatment of SUDsNovel pharmacological treatmentsFemale sex hormonesTreatment of menNovel pharmacological interventionsTobacco/nicotineFemale substance usersDrugs of abuseMetabolite allopregnanolonePharmacological treatmentPreliminary efficacySex hormonesPharmacological interventionsAvailable interventionsNovel treatmentsAllopregnanoloneEuphoric effectsProgesteroneNarrative reviewLiterature searchSubstance useSubstance users
2021
Sex differences in progestogen- and androgen-derived neurosteroids in vulnerability to alcohol and stress-related disorders
Peltier MR, Verplaetse TL, Mineur YS, Gueorguieva R, Petrakis I, Cosgrove KP, Picciotto MR, McKee SA. Sex differences in progestogen- and androgen-derived neurosteroids in vulnerability to alcohol and stress-related disorders. Neuropharmacology 2021, 187: 108499. PMID: 33600842, PMCID: PMC7992136, DOI: 10.1016/j.neuropharm.2021.108499.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsStress-related disordersAlcohol useMajor depressive disorderAlcohol-related disordersAlcohol use disorderPosttraumatic stress disorderStress regulation systemComplex comorbiditiesDepressive disorderProblematic alcohol useUse disordersAlcohol misuseTherapeutic potentialTrauma exposureSubstance abuseStress disorderAnxiety disordersDisordersExposure resultsProgestogensNeurosteroidsNegative affectWomenComorbiditiesMale counterparts
2019
Commentary on Tosun et al. (2019): Dynamic changes in sex hormones and smoking cessation
Peltier MR, McKee SA. Commentary on Tosun et al. (2019): Dynamic changes in sex hormones and smoking cessation. Addiction 2019, 114: 1814-1815. PMID: 31347245, PMCID: PMC6732031, DOI: 10.1111/add.14728.Peer-Reviewed Original Research