2024
Support vector machine prediction of individual Autism Diagnostic Observation Schedule (ADOS) scores based on neural responses during live eye-to-eye contact
Zhang X, Noah J, Singh R, McPartland J, Hirsch J. Support vector machine prediction of individual Autism Diagnostic Observation Schedule (ADOS) scores based on neural responses during live eye-to-eye contact. Scientific Reports 2024, 14: 3232. PMID: 38332184, PMCID: PMC10853508, DOI: 10.1038/s41598-024-53942-z.Peer-Reviewed Original ResearchConceptsAutism Diagnostic Observation ScheduleAutism spectrum disorderAutism Diagnostic Observation Schedule scoresEye-to-eye contactSocial difficultiesNeural processesNeural responsesObservation ScheduleSymptoms of autism spectrum disorderBehavioural symptoms of autism spectrum disorderNeural activity patternsLive interaction paradigmTD groupSupport vector machineNeural mechanismsSymptom severityADOS scoresBehavioral symptomsSpectrum disorderASD diagnosisNeural dataActivity patternsAutismClassification methodMultivariate classification methodsBody fat predictive of acute effects of exercise on prefrontal hemodynamics and speed
Crum J, Ronca F, Herbert G, Carmona E, Jones I, Hakim U, Hamer M, Hirsch J, Hamilton A, Tachtsidis I, Burgess P. Body fat predictive of acute effects of exercise on prefrontal hemodynamics and speed. Neuropsychologia 2024, 196: 108805. PMID: 38340963, DOI: 10.1016/j.neuropsychologia.2024.108805.Peer-Reviewed Original Research
2023
Neural mechanisms for emotional contagion and spontaneous mimicry of live facial expressions
Hirsch J, Zhang X, Noah J, Bhattacharya A. Neural mechanisms for emotional contagion and spontaneous mimicry of live facial expressions. Philosophical Transactions Of The Royal Society B Biological Sciences 2023, 378: 20210472. PMID: 36871593, PMCID: PMC9985973, DOI: 10.1098/rstb.2021.0472.Peer-Reviewed Original ResearchConceptsEmotional contagionFacial expressionsFacial mimicryNeural correlatesAffect ratingsDyadic partnersFace processing areasRatings of emotionDistinct neural componentsShort movie clipsTwo-person paradigmFacial action unitsSpontaneous mimicryNeural underpinningsEmotional experienceNeural mechanismsSupramarginal gyrusNatural facial expressionsAction unitsRest blocksMovie clipsSocial interactionFacial classificationMovie watchersDyadic roleVolume of subcortical brain regions in social anxiety disorder: mega-analytic results from 37 samples in the ENIGMA-Anxiety Working Group
Groenewold N, Bas-Hoogendam J, Amod A, Laansma M, Van Velzen L, Aghajani M, Hilbert K, Oh H, Salas R, Jackowski A, Pan P, Salum G, Blair J, Blair K, Hirsch J, Pantazatos S, Schneier F, Talati A, Roelofs K, Volman I, Blanco-Hinojo L, Cardoner N, Pujol J, Beesdo-Baum K, Ching C, Thomopoulos S, Jansen A, Kircher T, Krug A, Nenadić I, Stein F, Dannlowski U, Grotegerd D, Lemke H, Meinert S, Winter A, Erb M, Kreifelts B, Gong Q, Lui S, Zhu F, Mwangi B, Soares J, Wu M, Bayram A, Canli M, Tükel R, Westenberg P, Heeren A, Cremers H, Hofmann D, Straube T, Doruyter A, Lochner C, Peterburs J, Van Tol M, Gur R, Kaczkurkin A, Larsen B, Satterthwaite T, Filippi C, Gold A, Harrewijn A, Zugman A, Bülow R, Grabe H, Völzke H, Wittfeld K, Böhnlein J, Dohm K, Kugel H, Schrammen E, Zwanzger P, Leehr E, Sindermann L, Ball T, Fonzo G, Paulus M, Simmons A, Stein M, Klumpp H, Phan K, Furmark T, Månsson K, Manzouri A, Avery S, Blackford J, Clauss J, Feola B, Harper J, Sylvester C, Lueken U, Veltman D, Winkler A, Jahanshad N, Pine D, Thompson P, Stein D, Van der Wee N. Volume of subcortical brain regions in social anxiety disorder: mega-analytic results from 37 samples in the ENIGMA-Anxiety Working Group. Molecular Psychiatry 2023, 28: 1079-1089. PMID: 36653677, PMCID: PMC10804423, DOI: 10.1038/s41380-022-01933-9.Peer-Reviewed Original ResearchConceptsSocial anxiety disorderSubcortical brain regionsAnxiety disordersSAD patientsBilateral putamen volumesSubcortical regionsBrain regionsLinear mixed effects analysisComorbid anxiety disordersSubcortical volumesFamily-wise errorPutamen volumeSAD onsetVolumetric differencesPallidum volumeMixed effects analysisD effect sizesInconsistent findingsLeft putamenEffect sizeFull samplePrevious findingsInternational sampleSignificant interactionLimited convergence
2022
Rejection Distress Suppresses Medial Prefrontal Cortex in Borderline Personality Disorder
Fertuck E, Stanley B, Kleshchova O, Mann J, Hirsch J, Ochsner K, Pilkonis P, Erbe J, Grinband J. Rejection Distress Suppresses Medial Prefrontal Cortex in Borderline Personality Disorder. Biological Psychiatry Cognitive Neuroscience And Neuroimaging 2022, 8: 651-659. PMID: 36868964, PMCID: PMC10388534, DOI: 10.1016/j.bpsc.2022.11.006.Peer-Reviewed Original ResearchConceptsBorderline personality disorderRejection distressFunctional magnetic resonancePrefrontal cortex responsesCortex responsesPrefrontal cortexPersonality disorderControl participantsWhole-brain responsesNeural responsesFunctional magnetic resonance imagingMagnetic resonance imagingMedial prefrontal cortexHealthy control participantsUnivariate analysisMagnetic resonanceBPD groupResonance imagingNovel functional magnetic resonanceGroup differencesRostromedial prefrontal cortexNeural substratesBrain activityDistressNeural mechanismsTwo-person multimodal imaging using functional near infrared spectroscopy reveals neural mechanisms for emotional contagion
Hirsch J. Two-person multimodal imaging using functional near infrared spectroscopy reveals neural mechanisms for emotional contagion. 2022, 00: 1-2. DOI: 10.1109/ipc53466.2022.9975753.Peer-Reviewed Original ResearchFacial mimicryNeural mechanismsRight temporal parietal junctionLive face-to-face interactionEmotional contagionTemporal parietal junctionInteractive social behaviorBehavioral findingsNeural resultsEmotion ratingsNeural systemsSocial behaviorEmotional meaningFacial expressionsHuman brainFace-to-face interactionImaging studiesFacial classificationEmotionsFNIRSHypothesisBrainParticipantsContagionIndividualsNeural correlates of eye contact and social function in autism spectrum disorder
Hirsch J, Zhang X, Noah J, Dravida S, Naples A, Tiede M, Wolf J, McPartland J. Neural correlates of eye contact and social function in autism spectrum disorder. PLOS ONE 2022, 17: e0265798. PMID: 36350848, PMCID: PMC9645655, DOI: 10.1371/journal.pone.0265798.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderDorsal parietal regionsNeural correlatesEye contactLive eyesNeural responsesSpectrum disorderAutism Diagnostic Observation ScheduleUnderlying neural correlatesSocial Responsiveness ScaleGold standard measureCentral diagnostic criterionDiagnostic criteriaDiagnostic biomarkersSRS-2ADOS-2Responsiveness ScaleObservation ScheduleParietal regionsPupillometry dataNeural systemsEyesNatural interactionDisordersCorrelatesOptical imaging and spectroscopy for the study of the human brain: status report
Ayaz H, Baker WB, Blaney G, Boas DA, Bortfeld H, Brady K, Brake J, Brigadoi S, Buckley EM, Carp SA, Cooper RJ, Cowdrick KR, Culver JP, Dan I, Dehghani H, Devor A, Durduran T, Eggebrecht AT, Emberson LL, Fang Q, Fantini S, Franceschini MA, Fischer JB, Gervain J, Hirsch J, Hong KS, Horstmeyer R, Kainerstorfer JM, Ko TS, Licht DJ, Liebert A, Luke R, Lynch JM, Mesquida J, Mesquita RC, Naseer N, Novi SL, Orihuela-Espina F, O’Sullivan T, Peterka DS, Pifferi A, Pollonini L, Sassaroli A, Sato JR, Scholkmann F, Spinelli L, Srinivasan VJ, St. Lawrence K, Tachtsidis I, Tong Y, Torricelli A, Urner T, Wabnitz H, Wolf M, Wolf U, Xu S, Yang C, Yodh AG, Yücel MA, Zhou W. Optical imaging and spectroscopy for the study of the human brain: status report. Neurophotonics 2022, 9: s24001-s24001. PMID: 36052058, PMCID: PMC9424749, DOI: 10.1117/1.nph.9.s2.s24001.Peer-Reviewed Original ResearchActivation in Right Dorsolateral Prefrontal Cortex Underlies Stuttering Anticipation
Jackson E, Dravida S, Zhang X, Noah J, Gracco V, Hirsch J. Activation in Right Dorsolateral Prefrontal Cortex Underlies Stuttering Anticipation. Neurobiology Of Language 2022, 3: 469-494. PMID: 37216062, PMCID: PMC10158639, DOI: 10.1162/nol_a_00073.Peer-Reviewed Original ResearchDecreased Exercise-Induced Changes in Prefrontal Cortex Hemodynamics Are Associated With Depressive Symptoms
Crum J, Ronca F, Herbert G, Funk S, Carmona E, Hakim U, Jones I, Hamer M, Hirsch J, Hamilton A, Tachtsidis I, Burgess P. Decreased Exercise-Induced Changes in Prefrontal Cortex Hemodynamics Are Associated With Depressive Symptoms. Frontiers In Neuroergonomics 2022, 3: 806485. PMID: 38235451, PMCID: PMC10790946, DOI: 10.3389/fnrgo.2022.806485.Peer-Reviewed Original ResearchCardiopulmonary exercise testPhysical activityDepressive symptomsPrefrontal cortexActivation changesRostral prefrontal cortexExercise-induced changesExecutive function tasksMental health interventionsPrefrontal cortex hemodynamicsExecutive functionCPET assessmentFunction tasksAcute exerciseFunction testsExercise testAcute effectsInferior frontal gyrusExecutive function testsHealth interventionsNeural effectsAerobic fitnessDepressed moodSymptomsPhysical fitnessInvestigation of functional near-infrared spectroscopy signal quality and development of the hemodynamic phase correlation signal
Hakim U, Pinti P, Noah AJ, Zhang X, Burgess P, Hamilton A, Hirsch J, Tachtsidis I. Investigation of functional near-infrared spectroscopy signal quality and development of the hemodynamic phase correlation signal. Neurophotonics 2022, 9: 025001-025001. PMID: 35599691, PMCID: PMC9116886, DOI: 10.1117/1.nph.9.2.025001.Peer-Reviewed Original ResearchAn Approach to Neuroimaging Interpersonal Interactions in Mental Health Interventions
Crum J, Zhang X, Noah A, Hamilton A, Tachtsidis I, Burgess PW, Hirsch J. An Approach to Neuroimaging Interpersonal Interactions in Mental Health Interventions. Biological Psychiatry Cognitive Neuroscience And Neuroimaging 2022, 7: 669-679. PMID: 35144035, PMCID: PMC9271588, DOI: 10.1016/j.bpsc.2022.01.008.Peer-Reviewed Original ResearchConceptsInterpersonal interactionsPrefrontal cortexRostral prefrontal cortexInferior parietal lobuleMental health interventionsNeural underpinningsDysfunctional cognitionsBrain systemsEcological validityPrefrontal systemsParietal lobuleNeural couplingNeuroimaging techniquesVerbal communicationVerbal interactionClinical neuroscienceMental healthCortexClinical situationsClinical settingClinical tasksClinical interactionsParadigmHealth interventionsCognitionIntroduction—Tamas L. Horvath
Horváth T, Hirsch J, Molnár Z. Introduction—Tamas L. Horvath. 2022, xix-xxiv. DOI: 10.1016/b978-0-12-818093-8.00025-2.Peer-Reviewed Original ResearchChapter 2 Tamas Horvath: The hunger view on body, brain and behavior
Horváth T, Hirsch J, Molnár Z. Chapter 2 Tamas Horvath: The hunger view on body, brain and behavior. 2022, 67-146. DOI: 10.1016/b978-0-12-818093-8.00009-4.Peer-Reviewed Original ResearchIntroduction—Zoltán Molnár
Horváth T, Hirsch J, Molnár Z. Introduction—Zoltán Molnár. 2022, xiii-xvii. DOI: 10.1016/b978-0-12-818093-8.00017-3.Peer-Reviewed Original ResearchChapter 3 Joy Hirsch: Brain-to-Brain
Horváth T, Hirsch J, Molnár Z. Chapter 3 Joy Hirsch: Brain-to-Brain. 2022, 147-181. DOI: 10.1016/b978-0-12-818093-8.00008-2.Peer-Reviewed Original ResearchIntroduction—Joy Hirsch
Horváth T, Hirsch J, Molnár Z. Introduction—Joy Hirsch. 2022, xxv-xxviii. DOI: 10.1016/b978-0-12-818093-8.00019-7.Peer-Reviewed Original ResearchChapter 1 Zoltán Molnár: the developing brain
Horváth T, Hirsch J, Molnár Z. Chapter 1 Zoltán Molnár: the developing brain. 2022, 1-66. DOI: 10.1016/b978-0-12-818093-8.00005-7.Peer-Reviewed Original Research
2021
Extensive Prefrontal Cortex Haemodynamic Changes Provoked By Intense Aerobic Exercise, Measured Via FNIRS
Ronca F, Crum J, Jones I, Hirsch J, Hamilton A, Tachtsidis I, Burgess P. Extensive Prefrontal Cortex Haemodynamic Changes Provoked By Intense Aerobic Exercise, Measured Via FNIRS. Medicine & Science In Sports & Exercise 2021, 53: 315-315. DOI: 10.1249/01.mss.0000762824.50531.db.Peer-Reviewed Original ResearchBidirectional Connectivity Between Broca's Area and Wernicke's Area During Interactive Verbal Communication
Ono Y, Zhang X, Noah JA, Dravida S, Hirsch J. Bidirectional Connectivity Between Broca's Area and Wernicke's Area During Interactive Verbal Communication. Brain Connectivity 2021, 12: 210-222. PMID: 34128394, PMCID: PMC9058861, DOI: 10.1089/brain.2020.0790.Peer-Reviewed Original ResearchConceptsWernicke's areaNeural mechanismsBroca's areaDirectional connectivityHealthy adult participantsHemodynamic responseBidirectional connectivityFunctional connectivityNeural modulationBrainNeuronal informationSpeech areasNeural activityAdult participantsBrocaContrast findingsHuman brainImpact statementNeural dynamicsBrain modelFindingsWernicke'sSocial functionGranger causality analysisVerbal condition