Blood epigenome-wide association studies of suicide attempt in adults with bipolar disorder
Mirza S, Lima C, Del Favero-Campbell A, Rubinstein A, Topolski N, Cabrera-Mendoza B, Kovács E, Blumberg H, Richards J, Williams A, Wemmie J, Magnotta V, Fiedorowicz J, Gaine M, Walss-Bass C, Quevedo J, Soares J, Fries G. Blood epigenome-wide association studies of suicide attempt in adults with bipolar disorder. Translational Psychiatry 2024, 14: 70. PMID: 38296944, PMCID: PMC10831084, DOI: 10.1038/s41398-024-02760-y.Peer-Reviewed Original ResearchConceptsEpigenome-wide association studiesDifferentially methylated regionsDifferentially methylated positionsAssociation studiesCo-methylation network analysisBipolar disorderDNA methylation patternsSuicide attemptsReplication cohortHistory of SAGene ontology analysisSignificant CpG sitesMethylation patternsDNA methylationCpG sitesOntology analysisImmune-related genesEnrichment analysisNon-psychiatric controlsCalcium signalingGenesDNAClinical interviewSA historyNetwork analysis