2024
Experience of Euclidean geometry sculpts the development and dynamics of rodent hippocampal sequential cell assemblies
Farooq U, Dragoi G. Experience of Euclidean geometry sculpts the development and dynamics of rodent hippocampal sequential cell assemblies. Nature Communications 2024, 15: 8417. PMID: 39341810, PMCID: PMC11438871, DOI: 10.1038/s41467-024-52758-9.Peer-Reviewed Original Research
2021
Orientation selectivity enhances context generalization and generative predictive coding in the hippocampus
Liu K, Sibille J, Dragoi G. Orientation selectivity enhances context generalization and generative predictive coding in the hippocampus. Neuron 2021, 109: 3688-3698.e6. PMID: 34506724, PMCID: PMC8602755, DOI: 10.1016/j.neuron.2021.08.013.Peer-Reviewed Original Research
2020
The Ontogeny of Hippocampus-Dependent Memories
Donato F, Alberini CM, Amso D, Dragoi G, Dranovsky A, Newcombe NS. The Ontogeny of Hippocampus-Dependent Memories. Journal Of Neuroscience 2020, 41: 920-926. PMID: 33328296, PMCID: PMC7880290, DOI: 10.1523/jneurosci.1651-20.2020.Peer-Reviewed Original ResearchConceptsHippocampus-dependent memory systemHippocampus-dependent memoryMemory systemTypes of memoryMedial temporal lobeFormation of memoryMemory reliesMemory processesMemoryTemporal lobeInfant hippocampusBiological correlatesAdult systemActivity dynamicsHippocampusRecent evidenceLearningCorrelatesFirst yearAdultsAcquisitionInfancyLifeCircuitryPlace of acquisitionA consensus statement: defining terms for reactivation analysis
Genzel L, Dragoi G, Frank L, Ganguly K, de la Prida L, Pfeiffer B, Robertson E. A consensus statement: defining terms for reactivation analysis. Philosophical Transactions Of The Royal Society B Biological Sciences 2020, 375: 20200001. PMID: 32248790, PMCID: PMC7209922, DOI: 10.1098/rstb.2020.0001.Peer-Reviewed Original Research
2019
Strengthened Temporal Coordination within Pre-existing Sequential Cell Assemblies Supports Trajectory Replay
Farooq U, Sibille J, Liu K, Dragoi G. Strengthened Temporal Coordination within Pre-existing Sequential Cell Assemblies Supports Trajectory Replay. Neuron 2019, 103: 719-733.e7. PMID: 31253469, PMCID: PMC7197404, DOI: 10.1016/j.neuron.2019.05.040.Peer-Reviewed Original ResearchEmergence of preconfigured and plastic time-compressed sequences in early postnatal development
Farooq U, Dragoi G. Emergence of preconfigured and plastic time-compressed sequences in early postnatal development. Science 2019, 363: 168-173. PMID: 30630930, PMCID: PMC6794005, DOI: 10.1126/science.aav0502.Peer-Reviewed Original ResearchConceptsCritical cognitive functionsEpisodic memory formationHippocampal neuronal ensemblesMemory episodesCognitive functionMemory formationPostnatal week 4Postnatal week 3Neuronal ensemblesEarly postnatal developmentElectrophysiological activityNaïve ratsWeek 4Hippocampal neuronsPostnatal developmentWeek 3Eye openingFirst dayEncodingSequential patternsLinear environmentSleepReplay
2018
Preconfigured patterns are the primary driver of offline multi‐neuronal sequence replay
Liu K, Sibille J, Dragoi G. Preconfigured patterns are the primary driver of offline multi‐neuronal sequence replay. Hippocampus 2018, 29: 275-283. PMID: 30260526, PMCID: PMC6793999, DOI: 10.1002/hipo.23034.Peer-Reviewed Original ResearchGenerative Predictive Codes by Multiplexed Hippocampal Neuronal Tuplets
Liu K, Sibille J, Dragoi G. Generative Predictive Codes by Multiplexed Hippocampal Neuronal Tuplets. Neuron 2018, 99: 1329-1341.e6. PMID: 30146305, DOI: 10.1016/j.neuron.2018.07.047.Peer-Reviewed Original Research
2017
Impaired Tuning of Neural Ensembles and the Pathophysiology of Schizophrenia: A Translational and Computational Neuroscience Perspective
Krystal JH, Anticevic A, Yang GJ, Dragoi G, Driesen NR, Wang XJ, Murray JD. Impaired Tuning of Neural Ensembles and the Pathophysiology of Schizophrenia: A Translational and Computational Neuroscience Perspective. Biological Psychiatry 2017, 81: 874-885. PMID: 28434616, PMCID: PMC5407407, DOI: 10.1016/j.biopsych.2017.01.004.Peer-Reviewed Original ResearchConceptsNeural activityNeural ensemblesComputational neuroscience perspectiveHigher cognitive functionsNeuroscience perspectiveDevelopmental perspectiveDevelopmental correlatesCognitive functionNegative functional consequencesCortical networksComputational neuroscienceNeural codeCortical activityCognitive impairmentNeural dysfunctionAspartate glutamate receptor antagonistTemporal tuningSpatial tuningGlutamate receptor antagonistsPathophysiology of schizophreniaNeural network functionSchizophreniaPsychiatric disordersBalance of excitationInput-output curves