Elizabeth Ralevski, PhD
Research Scientist in PsychiatryCards
Appointments
Psychiatry
Primary
Contact Info
Psychiatry
300 George St
New Haven, CT 06511-
United States
About
Titles
Research Scientist in Psychiatry
Biography
Dr. Ralevski is an Assistant Professor of Psychiatry at Yale University School of Medicine and the Project Director for the Substance Abuse Treatment Program. Dr. Ralevski completed her Post Doctoral Fellowship at Harvard Medical School. She joined the faculty at Yale University in 2001. Her research interest include the search for appropriate treatment for individuals with dual diagnosis of alcoholism and other psychiatric conditions including depression, post traumatic stress disorder, schizophrenia and borderline personality disorder. Her other research examines factors, such as stress, that may lead to the development and maintenance of alcoholism and other mental disorders.
Appointments
Psychiatry
Research ScientistPrimary
Other Departments & Organizations
Education & Training
- Post Doctoral Fellowship
- Harvard University (2001)
- PhD
- York University (2000)
Research
Overview
Stress Reactivity in Veterans Receiving Pharmacological Treatment for PTSD and Alcohol Dependence
Medical Research Interests
Alcoholism; Comorbidity; Diagnosis, Dual (Psychiatry); Personality; Personality Disorders; Pharmacology; Psychiatry; Stress, Physiological
Research at a Glance
Yale Co-Authors
Frequent collaborators of Elizabeth Ralevski's published research.
Publications Timeline
A big-picture view of Elizabeth Ralevski's research output by year.
Research Interests
Research topics Elizabeth Ralevski is interested in exploring.
Jane Jane, PhD
Ismene Petrakis, MD
Erin O'Brien, PsyD
Jenelle Newcomb
MacKenzie Peltier, PhD
Sherry McKee, PhD
11Publications
226Citations
Alcoholism
Personality Disorders
Comorbidity
Diagnosis, Dual (Psychiatry)
Publications
2024
Cognitive processing therapy (CPT) versus individual drug counseling (IDC) for PTSD for veterans with opioid use disorder maintained on buprenorphine
Petrakis I, Meshberg‐Cohen S, Nich C, Kelly M, Claudio T, Jane J, Pisani E, Ralevski E. Cognitive processing therapy (CPT) versus individual drug counseling (IDC) for PTSD for veterans with opioid use disorder maintained on buprenorphine. American Journal On Addictions 2024, 33: 525-533. PMID: 38624259, DOI: 10.1111/ajad.13557.Peer-Reviewed Original ResearchAltmetricConceptsCognitive processing therapyIndividual drug counselingPosttraumatic stress disorderOpioid use disorderSubstance use disordersDrug counselingProcessing therapyPTSD symptomsUse disorderCognitive processing therapy groupEvidence-based trauma-focused psychotherapiesSelf-reported PTSD symptomsPosttraumatic stress disorder symptomsPosttraumatic stress disorder treatmentRemission of PTSD symptomsPosttraumatic Stress Disorder ChecklistComorbid opioid use disorderTrauma-focused psychotherapyTrauma-focused treatmentRates of comorbidityTreatment group differencesPCL-5Stress disorderGroup differencesRandomized clinical trialsThe role of neurosteroids in posttraumatic stress disorder and alcohol use disorder: A review of 10 years of clinical literature and treatment implications
Peltier M, Verplaetse T, Altemus M, Zakiniaeiz Y, Ralevski E, Mineur Y, Gueorguieva R, Picciotto M, Cosgrove K, Petrakis I, McKee S. The role of neurosteroids in posttraumatic stress disorder and alcohol use disorder: A review of 10 years of clinical literature and treatment implications. Frontiers In Neuroendocrinology 2024, 73: 101119. PMID: 38184208, PMCID: PMC11185997, DOI: 10.1016/j.yfrne.2023.101119.Peer-Reviewed Original ResearchCitationsConceptsPosttraumatic stress disorderAlcohol use disorderStress disorderContext of PTSDPTSD/AUDConcurrent posttraumatic stress disorderUnderlying neurobiological mechanismsUse disordersAlcohol-related variablesNeurobiological mechanismsPTSD diagnosisTreatment developmentTreatment implicationsBody of literatureNovel interventionsClinical literatureRole of neurosteroidsDisordersTreatment outcomesYears of researchAlcohol consumptionExogenous pregnenolonePharmacological treatmentBiological variablesAllopregnanolone
2023
Progesterone Attenuates the Stress Response in Individuals with Alcohol Dependence and Post-Traumatic Stress Disorder – A Pilot Study
Ralevski E, Newcomb J, Pisani E, DeNegre D, Peltier M, Jane J, Yoon G, Petrakis I. Progesterone Attenuates the Stress Response in Individuals with Alcohol Dependence and Post-Traumatic Stress Disorder – A Pilot Study. Journal Of Dual Diagnosis 2023, 20: 39-51. PMID: 38147491, PMCID: PMC11214330, DOI: 10.1080/15504263.2023.2294989.Peer-Reviewed Original ResearchCitationsAltmetricConceptsAlcohol use disorderStress-induced cravingCognitive performanceNegative affectNeutral scriptsStress disorderPost-traumatic stress disorderComorbid alcohol use disorderTraumatic Stress DisorderMeasures of cravingCurrent alcohol use disorderPositive emotionsTrauma scriptsPhysiological measuresCravingStress-induced symptomsTest sessionsPTSDAnxietyAffectUse disordersLaboratory sessionsCocaine dependenceAlcohol dependenceIndividuals
2012
Treatment for Comorbid Borderline Personality Disorder and Alcohol Use Disorders: A Review of the Evidence and Future Recommendations
Gianoli MO, Jane JS, O'Brien E, Ralevski E. Treatment for Comorbid Borderline Personality Disorder and Alcohol Use Disorders: A Review of the Evidence and Future Recommendations. Experimental And Clinical Psychopharmacology 2012, 20: 333-344. PMID: 22686496, PMCID: PMC3697118, DOI: 10.1037/a0027999.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsAlcohol use disorderBorderline personality disorderComorbid borderline personality disorderTreatment optionsSubstance use disordersUse disordersDual diagnosisBPD symptomsPersonality disorderPopulation of patientsSecond-generation antipsychoticsAlternative treatment optionPatterns of comorbiditySymptoms of BPDMedication optionsGeneration antipsychoticsPoor prognosisPharmacological treatmentSpecific psychotherapyRecent medicationAlcohol consumptionPatientsAlcohol cravingSymptomsDisordersSubjective Effects of Thiopental in Young Adults with and without a Family History of Alcoholism
Petrakis IL, Kerfoot K, Pittman B, Perrino A, Koretski J, Newcomb J, Limoncelli D, Acampora G, Ralevski E. Subjective Effects of Thiopental in Young Adults with and without a Family History of Alcoholism. Journal Of Addiction Research & Therapy 2012, 2013 PMID: 24273687, PMCID: PMC3835602, DOI: 10.4172/2155-6105.s7-002.Peer-Reviewed Original ResearchCitationsConceptsAlcohol use disorderSubjective effectsUse disordersSub-anesthetic dosesAlcohol-related measuresSignificant main effectCognitive effectsAlcohol-like effectsFHN individualsSeparate test daysStimulant effectsYoung adultsCognitionMain effectSubjective responsesAlcohol dependenceTest dayFamily historyImpaired coordinationIndividualsResponse differencesFamily history-negative subjectsDisordersHealthy individualsFHPCognitive deficits in schizophrenia and alcoholism: A review of the evidence and findings on the effects of pharmacological treatments on cognitive functioning in patients with dual diagnoses
Ralevski E, Gianoli MO, Russo, M, Dwan, R, Radhakrishnan, R. Cognitive deficits in schizophrenia and alcoholism: A review of the evidence and findings on the effects of pharmacological treatments on cognitive functioning in patients with dual diagnoses. Journal of Dual Diagnosis 2012, 8(3): 205-217. doi:10.1080/15504263.2012.696534Peer-Reviewed Original Research
2011
Preliminary Findings on the Interactive Effects of IV Ethanol and IV Nicotine on Human Behavior and Cognition: A Laboratory Study
Ralevski E, Perry EB, D’Souza D, Bufis V, Elander J, Limoncelli D, Vendetti M, Dean E, Cooper TB, McKee S, Petrakis I. Preliminary Findings on the Interactive Effects of IV Ethanol and IV Nicotine on Human Behavior and Cognition: A Laboratory Study. Nicotine & Tobacco Research 2011, 14: 596-606. PMID: 22180582, PMCID: PMC6281082, DOI: 10.1093/ntr/ntr258.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsRey Auditory Verbal Learning TaskAuditory Verbal Learning TaskVerbal learning taskAcute intravenous alcoholSubjective alcohol effectsBiphasic Alcohol Effects ScaleAlcohol-induced deficitsAlcohol-induced impairmentDoses of alcoholActive nicotineInteractive effectsTest dayCognitive inhibitionVerbal learningCognitive performanceLearning taskSubjective intoxicationAlcohol effectsHuman behaviorNicotine effectsIntravenous alcoholAlcohol infusionManner oneSubjective effectsCognitionNoradrenergic vs Serotonergic Antidepressant with or without Naltrexone for Veterans with PTSD and Comorbid Alcohol Dependence
Petrakis IL, Ralevski E, Desai N, Trevisan L, Gueorguieva R, Rounsaville B, Krystal JH. Noradrenergic vs Serotonergic Antidepressant with or without Naltrexone for Veterans with PTSD and Comorbid Alcohol Dependence. Neuropsychopharmacology 2011, 37: 996-1004. PMID: 22089316, PMCID: PMC3280636, DOI: 10.1038/npp.2011.283.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsPost-traumatic stress disorderSerotonin uptake inhibitorNorepinephrine uptake inhibitorUptake inhibitorAlcohol dependenceMale veteransTreatment of PTSDUse outcomesSymptoms of PTSDDouble-blind conditionsMain outcome measuresEvidence of efficacyComorbid alcohol dependenceCurrent diagnostic criteriaAlcohol use disorderAlcohol use outcomesComorbid conditionsAdjunctive efficacyOutcome measuresOnly FDADiagnostic criteriaUse disordersClinical advantagesAlcohol consumptionDrug AdministrationEffects of Acamprosate on Cognition in a Treatment Study of Patients With Schizophrenia Spectrum Disorders and Comorbid Alcohol Dependence
Ralevski E, O'Brien E, Jane JS, Dean E, Dwan R, Petrakis I. Effects of Acamprosate on Cognition in a Treatment Study of Patients With Schizophrenia Spectrum Disorders and Comorbid Alcohol Dependence. The Journal Of Nervous And Mental Disease 2011, 199: 499-505. PMID: 21716064, DOI: 10.1097/nmd.0b013e3182214297.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsCognitive functioningSchizophrenia spectrum disordersSpectrum disorderAlcohol dependenceComorbid alcohol dependencePsychotic symptomsSymptoms of psychosisCognitionEffects of acamprosateAlcohol useFunctioningTreatment studiesAlcohol reductionMemorySample of patientsAcamprosate treatmentGroup of patientsNegative effectsAlcohol consumptionDisordersAttentionSymptomsAcamprosatePatientsSchizophreniaTreatment With Acamprosate in Patients With Schizophrenia Spectrum Disorders and Comorbid Alcohol Dependence
Ralevski E, O’Brien E, Jane JS, Dwan R, Dean E, Edens E, Arnaout B, Keegan K, Drew S, Petrakis I. Treatment With Acamprosate in Patients With Schizophrenia Spectrum Disorders and Comorbid Alcohol Dependence. Journal Of Dual Diagnosis 2011, 7: 64-73. PMID: 26954912, DOI: 10.1080/15504263.2011.569440.Peer-Reviewed Original ResearchCitationsConceptsEfficacy of acamprosateAlcohol dependenceSchizophrenia spectrum disordersMedication treatmentComorbid schizophreniaSignificant group x time interactionGroup x time interactionComorbid alcohol dependenceAlcohol use disorderSymptoms of schizophreniaX time interactionAcamprosate groupComorbid conditionsTreatment trialsAbstinent patientsClinical trialsSpectrum disorderAcamprosateGeneral populationUse disordersPatientsSchizoaffective disorderPositive symptomsSchizophrenic symptomsConsecutive days
Clinical Trials
Current Trials
Alcohol Interaction Study
HIC ID2000030342RoleSub InvestigatorPrimary Completion Date01/31/2023Recruiting ParticipantsGenderBothAge21 years - 65 years
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Mailing Address
Psychiatry
300 George St
New Haven, CT 06511-
United States