2022
Mechanistic stoichiometric relationship between the rates of neurotransmission and neuronal glucose oxidation: Reevaluation of and alternatives to the pseudo‐malate‐aspartate shuttle model
Rothman D, Behar K, Dienel G. Mechanistic stoichiometric relationship between the rates of neurotransmission and neuronal glucose oxidation: Reevaluation of and alternatives to the pseudo‐malate‐aspartate shuttle model. Journal Of Neurochemistry 2022, 168: 555-591. PMID: 36089566, DOI: 10.1111/jnc.15619.Peer-Reviewed Original ResearchMitochondrial carriersSubcellular compartmentationCultured glutamatergic neuronsMechanistic basisMajor knowledge gapsMechanistic stoichiometryExtracellular GlnGlycolytic metabolismNeuronal compartmentsPre-synaptic structuresGlucose oxidationShuttle modelAlternative mechanismStoichiometric relationshipGlnDiseased brainNeuronal glucose metabolismMetabolismGluAminobutyric acidGlutamatergic neuronsKnowledge gapsCyclingMitochondriaCompartmentation
2002
Quantitative fMRI of rat brain by multi-modal MRI and MRS measurements
Hyder F, Kida I, Smith A, Blumenfeld H, Shulman R, Rothman D. Quantitative fMRI of rat brain by multi-modal MRI and MRS measurements. International Congress Series 2002, 1235: 57-71. DOI: 10.1016/s0531-5131(02)00173-5.Peer-Reviewed Original ResearchMagnetic resonance imagingRat brainNeuronal activityFunctional MRIBOLD fMRI signalCerebral cortexNeuronal glucose oxidationRat cerebral cortexFunctional magnetic resonance imagingFMRI signalsBOLD functional MRIQuantitative magnetic resonance imagingBlood oxygenation levelBOLD fMRI studiesMulti-modal magnetic resonance imagingQuantitative functional MRIGlutamatergic neuronsOxygen deliveryPhysiologic basisResonance imagingPhysiologic componentsCMRO2BrainBlood circulationOxygenation level