2024
Improvement in coping skills from culturally-adapted digital CBT for Spanish-speaking Hispanics with substance use disorder: Secondary analysis of a randomized clinical trial
Benitez B, Loya J, Jaramillo Y, Muro-Rodriguez N, Rojas Perez O, Nich C, Frankforter T, Paris M, Kiluk B. Improvement in coping skills from culturally-adapted digital CBT for Spanish-speaking Hispanics with substance use disorder: Secondary analysis of a randomized clinical trial. Journal Of Substance Use And Addiction Treatment 2024, 168: 209536. PMID: 39374899, DOI: 10.1016/j.josat.2024.209536.Peer-Reviewed Original ResearchMechanisms of cognitive behavioral therapyQuality of coping skillsCognitive behavioral therapySubstance use disordersPrimary substance useCoping skillsSubstance useCBT programOutpatient treatmentWeeks of outpatient treatmentDigital cognitive behavioral therapyMechanisms of behavior changeWithin-person increasesDaily substance useAdaptive coping skillsSecondary analysis of clinical trial dataTreatment mechanismsRandomized to 8Associated with reductionsBehavioral therapyAnalysis of clinical trial dataUse disorderGeneralizability of researchSecondary analysisSpanish-speaking Hispanic adults
2023
Percentage of negative urine drug screens as a clinically meaningful endpoint for RCTs evaluating treatment for cocaine use
Loya J, Babuscio T, Nich C, Alessi S, Rash C, Kiluk B. Percentage of negative urine drug screens as a clinically meaningful endpoint for RCTs evaluating treatment for cocaine use. Drug And Alcohol Dependence 2023, 248: 109947. PMID: 37276806, PMCID: PMC10498479, DOI: 10.1016/j.drugalcdep.2023.109947.Peer-Reviewed Original ResearchConceptsUrine drug screensClinical trialsMeaningful endpointsCocaine useLong-term clinical benefitBetter long-term outcomesDrug screensPsychosocial functioningNegative urine drug screensLong-term outcomesRandomized clinical trialsFuture clinical trialsBetter psychosocial functioningClinical benefitPharmacological treatmentContinuous abstinenceTreatment periodTreatment respondersSustained abstinenceSubstance useTrialsTreatmentMeaningful thresholdPooled datasetAbstinenceBreaking through social determinants of health: Results from a feasibility study of Imani Breakthrough, a community developed substance use intervention for Black and Latinx people
Jordan A, Costa M, Nich C, Swarbrick M, Babuscio T, Wyatt J, O'Connell M, Guy K, Blackman K, Anderson R, Reis G, Ocasio L, Crespo M, Bellamy C. Breaking through social determinants of health: Results from a feasibility study of Imani Breakthrough, a community developed substance use intervention for Black and Latinx people. Journal Of Substance Use And Addiction Treatment 2023, 153: 209057. PMID: 37207836, DOI: 10.1016/j.josat.2023.209057.Peer-Reviewed Original ResearchConceptsSocial determinantsMental Health Services AdministrationDimensions of wellnessCommunity-based participatory research approachRate of deathHealth Services AdministrationDrug overdose ratesSubset of participantsSubstance use interventionsWeek 12Opioid overdoseOverdose ratesSubstance misuseEthnic disparitiesDisparity gapParticipatory research approachAddiction servicesSubstance abuseWeeks of educationHealth equityMental healthSubstance useLatinx peopleIntervention programsServices AdministrationThe Rise and Fall of Substance Use During Treatment: Applying Recency and Expectancy Principles to Daily Substance Use Patterns
Benitez B, Frankforter T, Nich C, Kiluk BD. The Rise and Fall of Substance Use During Treatment: Applying Recency and Expectancy Principles to Daily Substance Use Patterns. Psychology Of Addictive Behaviors 2023, 37: 235-246. PMID: 35201805, PMCID: PMC9399316, DOI: 10.1037/adb0000824.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapySubstance use disordersSubstance use patternsSubstance useTherapy sessionsRandomized clinical trial dataComputerized cognitive behavioral therapyClinical trial dataOutpatient SUD treatmentNext therapy sessionClinical trialsTherapy daysTreatment mechanismsSUD treatmentUse disordersTreatment efficacyTreatment sessionsTherapeutic contactDaily substance useTrial dataSecondary analysisSUD severityBehavioral therapyDrug typeWeekly proportion
2020
A feasibility study providing substance use treatment in the Black church
Jordan A, Babuscio T, Nich C, Carroll KM. A feasibility study providing substance use treatment in the Black church. Journal Of Substance Use And Addiction Treatment 2020, 124: 108218. PMID: 33771290, DOI: 10.1016/j.jsat.2020.108218.Peer-Reviewed Original ResearchConceptsTechnology-based treatmentsClinical trialsSUD treatmentBlack adultsNonrandomized feasibility studyUrine toxicology screenHealth care disparitiesEvidence-based interventionsDSM-5 criteriaAdequate numberCognitive behavioral therapyDisseminable strategyUndertreated populationToxicology screenCurrent SUDCare disparitiesHealth advisorsBehavioral therapySubstance useMean numberTreatmentHigh uptakeFeasibility studyCBT4CBTTrialsShort- and long-term changes in substance-related coping as mediators of in-person and computerized CBT for alcohol and drug use disorders
Roos CR, Carroll KM, Nich C, Frankforter T, Kiluk BD. Short- and long-term changes in substance-related coping as mediators of in-person and computerized CBT for alcohol and drug use disorders. Drug And Alcohol Dependence 2020, 212: 108044. PMID: 32422538, PMCID: PMC7293942, DOI: 10.1016/j.drugalcdep.2020.108044.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyComputerized cognitive behavioral therapyPerson cognitive-behavioural therapySubstance use disordersMediation effectAlcohol use disorderComputer-delivered cognitive behavioural therapyUse disordersSame mediation effectSubstance-related copingCoping Strategies ScaleSignificant mediation effectMechanisms of changeMediational modelCoping skillsStrategies ScaleCBT4CBTStatistical mediatorCopingDrug use disordersSubstance useHeavy drinkingDisordersLong-term changesLong-term increaseComputerized Cognitive Behavioral Therapy for Substance Use Disorders in a Specialized Primary Care Practice: A Randomized Feasibility Trial to Address the RT Component of SBIRT.
Tetrault JM, Holt SR, Cavallo DA, O'Connor PG, Gordon MA, Corvino JK, Nich C, Carroll KM. Computerized Cognitive Behavioral Therapy for Substance Use Disorders in a Specialized Primary Care Practice: A Randomized Feasibility Trial to Address the RT Component of SBIRT. Journal Of Addiction Medicine 2020, 14: e303-e309. PMID: 32371660, DOI: 10.1097/adm.0000000000000663.Peer-Reviewed Original ResearchConceptsSubstance use disordersComputerized cognitive behavioral therapySubstance useCognitive behavioral therapySelf-reported substance useUse disordersTechnology-based treatmentsPrimary care settingSubstance use outcomesIntegrated addictions treatmentTechnology-based interventionsBehavioral therapyPrimary care practicesOverall positive outcomeSUD interventionsBrief interventionUnhealthy alcohol useDays abstinentPositive outcomesUse outcomesCare settingsAlcohol useStandard careAddiction treatmentTreatment settings
2016
Alexithymia and Addiction: A Review and Preliminary Data Suggesting Neurobiological Links to Reward/Loss Processing
Morie KP, Yip SW, Nich C, Hunkele K, Carroll KM, Potenza MN. Alexithymia and Addiction: A Review and Preliminary Data Suggesting Neurobiological Links to Reward/Loss Processing. Current Addiction Reports 2016, 3: 239-248. PMID: 27695665, PMCID: PMC5040368, DOI: 10.1007/s40429-016-0097-8.Peer-Reviewed Original ResearchReward/loss processingSubstance use disordersLoss processingRole of alexithymiaPreliminary fMRI dataUse disordersCocaine-dependent individualsEmotional awarenessNeural correlatesReward anticipationNeurobiological correlatesAlexithymiaNeurobiological linkFMRI dataSubstance useSubstance dependenceCocaine dependenceAddictionCorrelatesIndividualsDisordersProcessingAnticipationImpairment
2011
Mentorship for Alcohol Problems (MAP): A Peer to Peer Modular Intervention for Outpatients
Tracy K, Burton M, Miescher A, Galanter M, Babuscio T, Frankforter T, Nich C, Rounsaville B. Mentorship for Alcohol Problems (MAP): A Peer to Peer Modular Intervention for Outpatients. Alcohol And Alcoholism 2011, 47: 42-47. PMID: 22045903, PMCID: PMC3243439, DOI: 10.1093/alcalc/agr136.Peer-Reviewed Original ResearchConceptsOutpatient alcohol treatment programTreatment programSubstance useAlcohol problemsCommunity treatment programsAlcohol use disorderAlcohol treatment programsDelivery of treatmentReduction of alcoholStage IModular interventionNew interventionsPatient interestBiological measuresInterventionFocus groups
2010
Informal discussions in substance abuse treatment sessions with Spanish-speaking clients
Bamatter W, Carroll KM, Añez LM, Paris M, Ball SA, Nich C, Frankforter TL, Suarez-Morales L, Szapocznik J, Martino S. Informal discussions in substance abuse treatment sessions with Spanish-speaking clients. Journal Of Substance Use And Addiction Treatment 2010, 39: 353-363. PMID: 20817381, PMCID: PMC2967664, DOI: 10.1016/j.jsat.2010.07.005.Peer-Reviewed Original ResearchConceptsMotivational enhancement therapyStandard treatmentDrug Abuse Clinical Trials Network protocolTreatment sessionsSubstance abuse treatment outcomesSignificant inverse correlationHispanic clientsEarly treatment sessionsSession audiotapesTreatment outcomesSubstance abuse treatment sessionsEnhancement therapyClient motivationSubstance useInverse correlationTreatment fidelityNational InstituteTreatmentAdverse consequencesTrialsSessionsClient retentionMonolingual SpanishRelationship of cognitive function and the acquisition of coping skills in computer assisted treatment for substance use disorders
Kiluk BD, Nich C, Carroll KM. Relationship of cognitive function and the acquisition of coping skills in computer assisted treatment for substance use disorders. Drug And Alcohol Dependence 2010, 114: 169-176. PMID: 21050679, PMCID: PMC3046302, DOI: 10.1016/j.drugalcdep.2010.09.019.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyCognitive functioningCoping skillsBehavioral therapySubstance useCoping skills trainingMeasures of IQSubstance-dependent individualsSignificant indirect effectSubstance use outcomesChronic substance useNeuropsychological measuresNeuropsychological factorsSubstance use disordersComputerized versionHigher IQSkills trainingCognitive functionLower IQLittle previous researchIQDependent individualsPoor functioningUse outcomesCognitive impairmentQuality versus quantity: acquisition of coping skills following computerized cognitive–behavioral therapy for substance use disorders
Kiluk BD, Nich C, Babuscio T, Carroll KM. Quality versus quantity: acquisition of coping skills following computerized cognitive–behavioral therapy for substance use disorders. Addiction 2010, 105: 2120-2127. PMID: 20854334, PMCID: PMC2975828, DOI: 10.1111/j.1360-0443.2010.03076.x.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyComputerized CBT programEffects of CBTComputerized cognitive behavioral therapySubstance use disordersEffect of treatmentSubstance use outcomesRole-play taskTreatment completionHigh riskPrimary drugUse disordersAverage ageCommunity settingsBehavioral therapyPatient treatmentSubstance dependenceAlcohol useCBT programSubstance useUse outcomesComputerized versionParticipants' durationSignificant increaseTreatmentNeurocognitive indicators predict results of an informed-consent quiz among substance-dependent treatment seekers entering a randomized clinical trial.
Kiluk BD, Nich C, Carroll KM. Neurocognitive indicators predict results of an informed-consent quiz among substance-dependent treatment seekers entering a randomized clinical trial. Journal Of Studies On Alcohol And Drugs 2010, 71: 704-12. PMID: 20731975, PMCID: PMC2930500, DOI: 10.15288/jsad.2010.71.704.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyMeasures of intelligenceBrief neuropsychological screeningCurrent substance dependenceSubstance use outcomesParticipants meeting criteriaNeurocognitive indicatorsEnhanced consent proceduresNeuropsychological functioningCorrect recallSubstance use treatmentTraining versionNeuropsychological screeningTreatment seekersQuiz itemsSubstance useSubstance usersSubstance dependenceMeeting criteriaRecallParticipants' understandingQuiz scoresFalse quizParticipantsComprehension
2009
A Multisite Randomized Effectiveness Trial of Motivational Enhancement Therapy for Spanish-Speaking Substance Users
Carroll KM, Martino S, Ball SA, Nich C, Frankforter T, Anez LM, Paris M, Suarez-Morales L, Szapocznik J, Miller WR, Rosa C, Matthews J, Farentinos C. A Multisite Randomized Effectiveness Trial of Motivational Enhancement Therapy for Spanish-Speaking Substance Users. Journal Of Consulting And Clinical Psychology 2009, 77: 993-999. PMID: 19803579, PMCID: PMC2792592, DOI: 10.1037/a0016489.Peer-Reviewed Original ResearchConceptsMotivational enhancement therapyEnhancement therapySubstance useSubstance usersRandomized Effectiveness TrialIndividual sessionsCurrent substance useX time interactionTreatment condition interactionCondition x time interactionSubstance use problemsClinical trialsEffectiveness trialTreatment exposureTherapy phaseTreatment retentionTreatment sessionsHispanic adultsTherapyHeterogeneous groupHispanic individualsTime interactionIndividual treatmentTrialsUse problemsMindfulness Training and Stress Reactivity in Substance Abuse: Results from a Randomized, Controlled Stage I Pilot Study
Brewer JA, Sinha R, Chen JA, Michalsen RN, Babuscio TA, Nich C, Grier A, Bergquist KL, Reis DL, Potenza MN, Carroll KM, Rounsaville BJ. Mindfulness Training and Stress Reactivity in Substance Abuse: Results from a Randomized, Controlled Stage I Pilot Study. Substance Abuse 2009, 30: 306-317. PMID: 19904666, PMCID: PMC3045038, DOI: 10.1080/08897070903250241.Peer-Reviewed Original ResearchConceptsSubstance use disordersCognitive behavioral therapyUse disordersDrug useStress reactivityMindfulness trainingCocaine use disorderTreatment satisfactionOutpatient settingStage IStress provocationBehavioral therapySubstance abuseTreatment acceptabilityPilot studySubstance useTreatmentDisordersProvocationPhysiological indicesRandomizedTherapyStudyIndividualsWeekly
2008
What is usual about “treatment-as-usual”? Data from two multisite effectiveness trials
Santa Ana EJ, Martino S, Ball SA, Nich C, Frankforter TL, Carroll KM. What is usual about “treatment-as-usual”? Data from two multisite effectiveness trials. Journal Of Substance Use And Addiction Treatment 2008, 35: 369-379. PMID: 18337053, PMCID: PMC2712113, DOI: 10.1016/j.jsat.2008.01.003.Peer-Reviewed Original ResearchConceptsEffectiveness trialDrug Abuse Clinical Trials NetworkSubstance useMultisite effectiveness trialClinical Trials NetworkStandard clinical practiceParticipants' substance useCommunity-based drug abuse treatmentDrug abuse treatmentNumber of interventionsSubstance use outcomesPatient outcomesClinical practiceTrials NetworkAbuse treatmentUse outcomesNational InstituteSocial functioningTreatmentTrialsOpen-ended questionsOutcomesStandard practiceEarly stagesEarly sessions
2007
Site Matters: Multisite Randomized Trial of Motivational Enhancement Therapy in Community Drug Abuse Clinics
Ball SA, Martino S, Nich C, Frankforter TL, Van Horn D, Crits-Christoph P, Woody GE, Obert JL, Farentinos C, Carroll KM. Site Matters: Multisite Randomized Trial of Motivational Enhancement Therapy in Community Drug Abuse Clinics. Journal Of Consulting And Clinical Psychology 2007, 75: 556-567. PMID: 17663610, PMCID: PMC2148493, DOI: 10.1037/0022-006x.75.4.556.Peer-Reviewed Original ResearchConceptsMotivational enhancement therapySubstance useEnhancement therapyBrief intervention conditionsOutpatient substance abuse programsSubstance use reductionDrug abuse clinicsSubstance abuse programsSession audiotapesRandomized trialsClinical trialsMultisite Randomized TrialSustained reductionTherapy phaseDrug usersPrimary alcohol usersAlcohol usersAbuse programsIntervention conditionSignificant increaseTherapyTrialsCAUOutpatientsClinicA Cognitive Behavioral Therapy for Alcohol‐Dependent Domestic Violence Offenders: An Integrated Substance Abuse–Domestic Violence Treatment Approach (SADV)
Easton CJ, Mandel DL, Hunkele KA, Nich C, Rounsaville BJ, Carroll KM. A Cognitive Behavioral Therapy for Alcohol‐Dependent Domestic Violence Offenders: An Integrated Substance Abuse–Domestic Violence Treatment Approach (SADV). American Journal On Addictions 2007, 16: 24-31. PMID: 17364418, DOI: 10.1080/10550490601077809.Peer-Reviewed Original ResearchConceptsAlcohol-dependent malesHistory of IPVCognitive-behavioral group therapyInterpersonal violenceBehavioral group therapyCognitive behavioral therapyGroup therapy approachSubstance abuse treatmentDomestic violence offendersBehavioral therapyDomestic violence groupGroup therapyAbuse treatmentNumber of sessionsSubstance useContingency Management to Reduce Substance Use in Individuals Who are Homeless with Co-Occurring Psychiatric Disorders
Tracy K, Babuscio T, Nich C, Kiluk B, Carroll KM, Petry NM, Rounsaville BJ. Contingency Management to Reduce Substance Use in Individuals Who are Homeless with Co-Occurring Psychiatric Disorders. The American Journal Of Drug And Alcohol Abuse 2007, 33: 253-258. PMID: 17497548, PMCID: PMC3390023, DOI: 10.1080/00952990601174931.Peer-Reviewed Original Research
2001
Perspective is everything: the predictive validity of six working alliance instruments.
Fenton LR, Cecero JJ, Nich C, Frankforter TL, Carroll KM. Perspective is everything: the predictive validity of six working alliance instruments. American Journal Of Psychotherapy 2001, 10: 262-8. PMID: 11696653, PMCID: PMC3330662.Peer-Reviewed Original ResearchConceptsObserver-rated instrumentsAlliance ScaleVanderbilt Therapeutic Alliance ScaleManual-guided therapiesTwelve-step facilitationObjective outcome measuresCalifornia Psychotherapy Alliance ScalesPredictive validityTherapeutic Alliance ScaleCognitive behavioral therapyWorking Alliance InventoryClinical trialsOutcome measuresAlliance instrumentsRating ScaleSubstance useTherapist-rated measureTherapeutic allianceAlliance InventoryTherapyOutcomes