Featured Publications
Antiplatelet regimens following carotid artery revascularization
Lee M, Ahmed ZV, Huang J, Brice A, Arham A, Castro-Dominguez Y, Aboian E, Nagpal S, Smolderen KG, Mena-Hurtado C. Antiplatelet regimens following carotid artery revascularization. American Heart Journal 2022, 253: 48-52. PMID: 35863439, DOI: 10.1016/j.ahj.2022.07.004.Peer-Reviewed Original ResearchConceptsDual antiplatelet therapySingle antiplatelet therapyCarotid artery stentingCarotid endarterectomyAntiplatelet therapyReal-world clinical practiceCarotid artery revascularizationLow adherence ratesArtery revascularizationArtery stentingAdherence ratesClinical practicePatientsTherapyEngland dataHigh percentageRevascularizationAntiplateletEndarterectomyStentingUse of drug-coated balloons and stents in patients with femoropopliteal artery disease and severe chronic kidney disease
Castro-Dominguez Y, Smolderen K, Romain G, Turner J, Mena-Hurtado C. Use of drug-coated balloons and stents in patients with femoropopliteal artery disease and severe chronic kidney disease. Vascular Medicine 2023, 28: 150-152. PMID: 36710497, DOI: 10.1177/1358863x221148521.Peer-Reviewed Original Research
2022
Use of linked registry claims data for long term surveillance of devices after endovascular abdominal aortic aneurysm repair: observational surveillance study
Goodney P, Mao J, Columbo J, Suckow B, Schermerhorn M, Malas M, Brooke B, Hoel A, Scali S, Arya S, Spangler E, Alabi O, Beck A, Gladders B, Moore K, Zheng X, Eldrup-Jorgensen J, Sedrakyan A, Organization S, Giles K, Beach J, Clouse W, Stone D, Randall M, Mansukhani N, Wang G, Woo K, Mureebe L, Dalsing M, Maijub J, Chaar C, Duwayri Y, Bertges D, Mena-Hurtado C, Smolderen K, Berman S, Osborne N, Henke P, Cronenwett J. Use of linked registry claims data for long term surveillance of devices after endovascular abdominal aortic aneurysm repair: observational surveillance study. The BMJ 2022, 379: e071452. PMID: 36283705, PMCID: PMC9593227, DOI: 10.1136/bmj-2022-071452.Peer-Reviewed Original ResearchConceptsEndovascular abdominal aortic aneurysm repairAbdominal aortic aneurysm repairObservational surveillance studyRisk of reinterventionAortic aneurysm repairLong-term outcomesAFX deviceReal-world practiceAneurysm repairTerm outcomesClaims dataCox modelSurveillance studyVascular Quality Initiative registrySurveillance dataLong-term reinterventionAbdominal aortic aneurysmLong-term surveillanceUnited States MedicareReintervention rateMedian agePost-EVARAortic aneurysmAortic endograftsReintervention
2021
Principles of Intravascular Lithotripsy for Calcific Plaque Modification
Kereiakes DJ, Virmani R, Hokama JY, Illindala U, Mena-Hurtado C, Holden A, Hill JM, Lyden SP, Ali ZA. Principles of Intravascular Lithotripsy for Calcific Plaque Modification. JACC Cardiovascular Interventions 2021, 14: 1275-1292. PMID: 34167671, DOI: 10.1016/j.jcin.2021.03.036.Peer-Reviewed Original ResearchConceptsIntravascular lithotripsyPeri-procedural adverse eventsLower procedural success ratesProcedural success rateUnfavorable clinical outcomePeripheral vascular bedsCalcium fractureIVL useAdverse eventsClinical outcomesPlaque modificationLuminal gainTranscatheter interventionsPlaque lesionsCalcific plaquesPeripheral vasculatureVascular bedClinical dataCardiovascular therapyStent expansionSuccess rateLesionsSignificant proportionLithotripsy technologyPlaques
2020
Intravascular Lithotripsy for Treatment of Calcified Lesions During Carotid Artery Stenting
Giannopoulos S, Speziale F, Vadalà G, Soukas P, Kuhn BA, Stoltz CL, Foteh MI, Mena-Hurtado C, Armstrong EJ. Intravascular Lithotripsy for Treatment of Calcified Lesions During Carotid Artery Stenting. Journal Of Endovascular Therapy 2020, 28: 93-99. PMID: 32869718, DOI: 10.1177/1526602820954244.Peer-Reviewed Original ResearchConceptsCarotid artery lesionsIntravascular lithotripsyArtery lesionsCarotid duplex ultrasound examinationAortic arch manipulationDual antiplatelet therapyCarotid artery stentingEmbolic protection devicesDuplex ultrasound examinationCarotid artery stenosisLong-term safetyArch manipulationBaseline stenosisAntiplatelet therapyAsymptomatic patientsSignificant restenosisIschemic strokeISR lesionsRisk patientsStent restenosesTransfemoral accessAdverse eventsArtery stentingArtery stenosisSymptomatic bradycardiaSafety and efficacy of paclitaxel drug-coated balloon in femoropopliteal in-stent restenosis
Anantha-Narayanan M, Love K, Nagpal S, Sheikh AB, Regan CJ, Mena-Hurtado C. Safety and efficacy of paclitaxel drug-coated balloon in femoropopliteal in-stent restenosis. Expert Review Of Medical Devices 2020, 17: 533-539. PMID: 32525406, DOI: 10.1080/17434440.2020.1770593.Peer-Reviewed Original ResearchConceptsDrug-coated balloonsPlain old balloon angioplastyPeripheral arterial diseaseFP-ISRFP diseaseStent restenosisEfficacy of DCBUse of DCBPaclitaxel drug-coated balloonFirst-line therapyRecurrence of symptomsSelf-expanding nitinol stentsHigher patency rateLong-term safetyLesion revascularizationEndovascular therapyISR rateRandomized studyArterial diseaseBalloon angioplastyFemoropopliteal segmentPatency ratesCommon siteTerm safetyNitinol stents
2019
Evaluation of anticoagulant and antiplatelet therapy after iliocaval stenting: Factors associated with stent occlusion
Attaran RR, Ozdemir D, Lin IH, Mena-Hurtado C, Lansky A. Evaluation of anticoagulant and antiplatelet therapy after iliocaval stenting: Factors associated with stent occlusion. Journal Of Vascular Surgery Venous And Lymphatic Disorders 2019, 7: 527-534. PMID: 31203859, DOI: 10.1016/j.jvsv.2019.01.058.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAnticoagulantsEndovascular ProceduresFemaleHumansIliac VeinMaleMay-Thurner SyndromeMiddle AgedPlatelet Aggregation InhibitorsPostthrombotic SyndromeProsthesis DesignRecurrenceRetrospective StudiesStentsTime FactorsTreatment OutcomeVascular PatencyVena Cava, InferiorVenous ThrombosisConceptsAcute deep vein thrombosisPost-thrombotic syndromeDeep vein thrombosisMay-Thurner syndromeDuration of anticoagulationAntiplatelet therapyPatency ratesIliocaval stentingIpsilateral deep vein thrombosisIliocaval venous stentingPrimary patency rateStent patency ratesCommon femoral veinVariety of indicationsLarge teaching hospitalVein thrombosisVenous stentingRetrospective reviewDVT groupStent groupFemoral veinProcedural dataStent patencyStent occlusionTeaching hospitalEndovascular Treatment of Inferior Vena Cava Thrombosis in Metastatic Malignancy: A Case Report and Review of Literature
Shapero KS, Jelani QU, Mena C. Endovascular Treatment of Inferior Vena Cava Thrombosis in Metastatic Malignancy: A Case Report and Review of Literature. Vascular And Endovascular Surgery 2019, 53: 507-511. PMID: 31216954, DOI: 10.1177/1538574419857992.Peer-Reviewed Original ResearchConceptsInferior vena cava thrombosisLower extremity edemaVena cava thrombosisAcute liver failureRight atriumIVC thrombosisCava thrombosisExtremity edemaLiver failureSevere bilateral lower extremity edemaBilateral lower extremity edemaAdrenal cell carcinomaExtensive clot burdenExtensive IVC thrombosisMetastatic liver massesDeep vein thrombosisClot burdenIVC syndromeReview of literatureGastrointestinal bleedHospital courseVein thrombosisHepatic failureCaudate lobeEndovascular treatment
2016
Carotid artery stenting versus carotid endarterectomy
Nanna MG, Gomes P, Njoh RF, Ward C, Attaran RR, Mena C. Carotid artery stenting versus carotid endarterectomy. Postgraduate Medical Journal 2016, 92: 532-539. PMID: 27317752, DOI: 10.1136/postgradmedj-2015-133689.Peer-Reviewed Original ResearchConceptsCarotid endarterectomyCarotid artery stentingCarotid artery stenosisArtery stentingMedical therapyArtery stenosisCarotid stenosisTreatment optionsSurgical techniqueTreatment strategiesCarotid arteryMajor causeEndarterectomyStenosisStrokeMorbidityStentingArterySignificant contributorOptionsTherapyMortalityTrialsCarotid stenting versus endarterectomy for the treatment of carotid artery stenosis: Contemporary results from a large single center study
Meller SM, Al‐Damluji M, Gutierrez A, Stilp E, Mena‐Hurtado C. Carotid stenting versus endarterectomy for the treatment of carotid artery stenosis: Contemporary results from a large single center study. Catheterization And Cardiovascular Interventions 2016, 88: 822-830. PMID: 27219323, DOI: 10.1002/ccd.26593.Peer-Reviewed Original ResearchConceptsBaseline medical comorbiditiesMedical comorbiditiesComposite endpointMyocardial infarctionSymptom statusCarotid revascularizationCarotid endarterectomy (CEA) versus carotid arteryPrimary end pointCause of strokeOccurrence of strokeEmbolic protection devicesCarotid artery stenosisMultivariate regression analysisHigh ratePeriprocedural deathPeriprocedural strokeComplication rateArtery stenosisCarotid stenosisPatient populationCarotid arteryComorbiditiesEnd pointStrokePatientsA Unique Case of May-Thurner Syndrome Extrinsic Compression of the Common Iliac Vein After Iliac Artery Stenting
Hermany PL, Badheka AO, Mena-Hurtado CI, Attaran RR. A Unique Case of May-Thurner Syndrome Extrinsic Compression of the Common Iliac Vein After Iliac Artery Stenting. JACC Cardiovascular Interventions 2016, 9: e39-e41. PMID: 26896887, DOI: 10.1016/j.jcin.2015.11.042.Peer-Reviewed Original Research
2015
Comparison of Inhospital Outcomes and Hospitalization Costs of Peripheral Angioplasty and Endovascular Stenting
Panaich SS, Arora S, Patel N, Patel NJ, Lahewala S, Solanki S, Manvar S, Savani C, Jhamnani S, Singh V, Patel SV, Thakkar B, Patel A, Deshmukh A, Chothani A, Bhatt P, Savani GT, Patel J, Mavani K, Bhimani R, Tripathi B, Mohamad T, Remetz MS, Curtis JP, Attaran RR, Grines C, Mena CI, Cleman M, Forrest JK, Badheka AO. Comparison of Inhospital Outcomes and Hospitalization Costs of Peripheral Angioplasty and Endovascular Stenting. The American Journal Of Cardiology 2015, 116: 634-641. PMID: 26096999, DOI: 10.1016/j.amjcard.2015.05.031.Peer-Reviewed Original ResearchConceptsLower amputation ratesInhospital mortalityPostprocedural complicationsHospitalization costsEndovascular stentingAmputation rateUtilization Project Nationwide Inpatient Sample databaseTwo-level hierarchical multivariateNationwide Inpatient Sample databaseComposite end pointPeripheral arterial diseaseHigher hospitalization costsAppropriate International ClassificationPeripheral endovascular interventionsInhospital outcomesSecondary outcomesPeripheral angioplastyPrimary outcomeArterial diseaseClinical outcomesStudy cohortNinth RevisionPatency ratesEndovascular interventionAngioplasty
2014
Randomized Controlled Study of Excimer Laser Atherectomy for Treatment of Femoropopliteal In-Stent Restenosis Initial Results From the EXCITE ISR Trial (EXCImer Laser Randomized Controlled Study for Treatment of FemoropopliTEal In-Stent Restenosis)
Dippel EJ, Makam P, Kovach R, George JC, Patlola R, Metzger DC, Mena-Hurtado C, Beasley R, Soukas P, Colon-Hernandez PJ, Stark MA, Walker C, Investigators E. Randomized Controlled Study of Excimer Laser Atherectomy for Treatment of Femoropopliteal In-Stent Restenosis Initial Results From the EXCITE ISR Trial (EXCImer Laser Randomized Controlled Study for Treatment of FemoropopliTEal In-Stent Restenosis). JACC Cardiovascular Interventions 2014, 8: 92-101. PMID: 25499305, DOI: 10.1016/j.jcin.2014.09.009.Peer-Reviewed Original ResearchMeSH KeywordsAgedAlloysAmputation, SurgicalAngioplasty, BalloonAtherectomyChronic DiseaseCombined Modality TherapyConstriction, PathologicFemaleFemoral ArteryHumansLaser TherapyLasers, ExcimerLimb SalvageMaleMiddle AgedPeripheral Arterial DiseasePopliteal ArteryProspective StudiesProsthesis DesignRecurrenceStentsTime FactorsTreatment OutcomeUnited StatesVascular PatencyConceptsPercutaneous transluminal angioplastyTarget lesion revascularizationExcimer laser atherectomyLaser atherectomyAdjunctive percutaneous transluminal angioplastyMajor adverse event rateChronic peripheral artery diseaseLesion lengthLifestyle-limiting claudicationPrimary safety endpointRutherford class 1Target lesion lengthPrimary efficacy endpointMajor adverse eventsPeripheral artery diseaseAdverse event ratesCritical limb ischemiaFemoropopliteal ISRLesion revascularizationEfficacy endpointSafety endpointAdverse eventsLimb ischemiaTransluminal angioplastyArtery diseaseDysautonomic responses during percutaneous carotid intervention
Bujak M, Stilp E, Meller SM, Cal N, Litsky J, Setaro JF, Mena C. Dysautonomic responses during percutaneous carotid intervention. Catheterization And Cardiovascular Interventions 2014, 85: 282-291. PMID: 25131191, DOI: 10.1002/ccd.25622.Peer-Reviewed Original ResearchConceptsCarotid artery stentingPercutaneous carotid artery stentingPostganglionic sympathetic nerve activityNeuro-vascular complicationsSympathetic nerve activityLong-term outcomesCarotid atherosclerotic diseaseLong-term safetyAutonomic dysfunctionBaroreceptor stimulationPeriprocedural managementPeriprocedural periodArtery stentingNerve activityAtherosclerotic diseaseCarotid endarterectomyPrognostic significanceRetrospective studyCarotid sinusRisk factorsBalloon inflationInvasive alternativeProcedural experienceConsistent findingHomeostasis resultsManagement of Symptomatic Carotid Disease in 2014
Litsky J, Stilp E, Njoh R, Mena-Hurtado C. Management of Symptomatic Carotid Disease in 2014. Current Cardiology Reports 2014, 16: 462. PMID: 24464307, DOI: 10.1007/s11886-013-0462-3.Peer-Reviewed Original ResearchConceptsSymptomatic carotid stenosisCarotid artery stentingCarotid endarterectomyCarotid stenosisMedical therapyHigh-grade symptomatic carotid stenosisExtracranial carotid artery stenosisPreventive medical therapyClass I recommendationSymptomatic carotid diseaseCarotid artery stenosisCause of deathRetinal symptomsStroke preventionArtery stentingI recommendationLandmark trialsPerioperative eventsArtery stenosisCarotid diseaseSymptomatic lesionsNoninvasive evaluationStenosisTherapyModern management
2013
Carotid stent deformation: Sonographic findings and CT correlation
Millet JD, Stilp E, Kirsch JD, Gunabushanam G, Mena C, Pollak J, Scoutt LM. Carotid stent deformation: Sonographic findings and CT correlation. Journal Of Clinical Ultrasound 2013, 42: 313-317. PMID: 24926493, DOI: 10.1002/jcu.22108.Peer-Reviewed Case Reports and Technical NotesAn evidence‐based review of the impact of periprocedural myocardial infarction in carotid revascularization
Stilp E, Baird C, Gray WA, Schneider PA, Simonton CA, Verta P, Mena‐Hurtado C. An evidence‐based review of the impact of periprocedural myocardial infarction in carotid revascularization. Catheterization And Cardiovascular Interventions 2013, 82: 709-714. PMID: 23765902, DOI: 10.1002/ccd.25056.Peer-Reviewed Original ResearchConceptsPeriprocedural myocardial infarctionCarotid endarterectomyRevascularization strategyCarotid revascularizationMyocardial infarctionCarotid arteryIncidence of PMIAsymptomatic atherosclerotic stenosisCarotid revascularization strategiesPatient symptom statusLong-term morbidityCarotid artery stenosisExtracranial carotid arteriesEvidence-based reviewAsymptomatic patientsRevascularization TrialLandmark trialsMedical therapyArtery stenosisRandomized comparisonAtherosclerotic stenosisSymptom statusInvasive optionBiomarker assessmentRevascularizationCarotid Revascularization: A Systematic Review of the Evidence
AL‐DAMLUJI M, NAGPAL S, STILP E, REMETZ M, MENA C. Carotid Revascularization: A Systematic Review of the Evidence. Journal Of Interventional Cardiology 2013, 26: 399-410. PMID: 23844747, DOI: 10.1111/joic.12037.Peer-Reviewed Original ResearchConceptsCarotid artery stentingProspective clinical trialsHigh surgical risk patientsSurgical risk patientsEmbolic protection devicesCarotid endarterectomyClinical trialsRisk patientsMyocardial infarctionIncidence rateSafety of CASEffective stroke prevention strategiesHigh surgical risk candidatesLong-term outcome ratesObjective performance criteriaTrials (RCTs) comparing outcomesHigh surgical riskStroke prevention strategiesEvidence-based reviewPatient selection strategiesLong-term effectivenessArtery stentingPeriprocedural safetySurgical riskComparing outcomes