2019
Genomewide Gene-by-Sex Interaction Scans Identify ADGRV1 for Sex Differences in Opioid Dependent African Americans
Yang BZ, Zhou H, Cheng Z, Kranzler HR, Gelernter J. Genomewide Gene-by-Sex Interaction Scans Identify ADGRV1 for Sex Differences in Opioid Dependent African Americans. Scientific Reports 2019, 9: 18070. PMID: 31792237, PMCID: PMC6889277, DOI: 10.1038/s41598-019-53560-0.Peer-Reviewed Original ResearchMeSH KeywordsAdultAllelesAnalgesics, OpioidBlack or African AmericanBrainCalcium-Binding ProteinsFemaleGene Expression ProfilingGenetic Predisposition to DiseaseGenome-Wide Association StudyHumansMaleMiddle AgedOpioid-Related DisordersPolymorphism, Single NucleotideReceptors, G-Protein-CoupledReceptors, Kainic AcidSex FactorsWhite PeopleConceptsOpioid dependenceOD riskSex-different effectsSex differencesInferior olivary nucleusDSM-IV diagnosisDimorphic riskSubstantia nigraAA menOlivary nucleusFrontal cortexEuropean-American subjectsADGRV1Further studiesRiskAfrican AmericansGenetic variantsDisease enrichment analysisBrainSex interactionNominal significanceMenFirst studyPutamenLung
2012
GABRA2 Genotype, Impulsivity, and Body Mass
Bauer LO, Yang B, Houston RJ, Kranzler HR, Gelernter J. GABRA2 Genotype, Impulsivity, and Body Mass. American Journal On Addictions 2012, 21: 404-410. PMID: 22882390, PMCID: PMC3773931, DOI: 10.1111/j.1521-0391.2012.00252.x.Peer-Reviewed Original ResearchMeSH KeywordsAdultAttention Deficit Disorder with HyperactivityBody Mass IndexCase-Control StudiesConnecticutFemaleGenotypeHumansImpulsive BehaviorMaleMiddle AgedPolymorphism, Single NucleotidePsychiatric Status Rating ScalesReceptors, GABA-ASex FactorsSubstance Abuse Treatment CentersSubstance-Related DisordersConceptsBody mass indexElevated body mass indexAssociation of BMIGABRA2 genotypeSubstance dependenceAttention-deficit/hyperactivity disorderHigh-calorie foodsPrevious pregnancyMass indexElectroencephalographic featuresRisk factorsChildhood symptomsScale scoreDrug abstinenceCalorie foodsHyperactivity disorderGenetic findingsWomenLonger durationBarratt Impulsiveness ScalePsychological indicatorsGABRA2 variantsSex differencesSecond analysisBody mass