2024
Neural Correlates of Novelty-Evoked Distress in 4-Month-Old Infants: A Synthetic Cohort Study
Filippi C, Winkler A, Kanel D, Elison J, Hardiman H, Sylvester C, Pine D, Fox N. Neural Correlates of Novelty-Evoked Distress in 4-Month-Old Infants: A Synthetic Cohort Study. Biological Psychiatry Cognitive Neuroscience And Neuroimaging 2024, 9: 905-914. PMID: 38641209, PMCID: PMC11381178, DOI: 10.1016/j.bpsc.2024.03.008.Peer-Reviewed Original ResearchBrain-behavior associationsParent-report measuresInfant temperamentNetwork pairsDorsal attention network connectivityAssessment of infant temperamentParent-reported temperamentAttention network connectivityControl network connectivitySocial anxietyFMRI studyNeural correlatesNeural basisFunctional connectivityParent reportNeuroimaging dataTemperamentAttention-controlComposite scoreDistressNetwork connectivityObservational assessmentNegative associationBehavior estimationDorsal
2022
Translating Big Data to Clinical Outcomes in Anxiety: Potential for Multimodal Integration
Khosravi P, Zugman A, Amelio P, Winkler A, Pine D. Translating Big Data to Clinical Outcomes in Anxiety: Potential for Multimodal Integration. Current Psychiatry Reports 2022, 24: 841-851. PMID: 36469202, PMCID: PMC9931491, DOI: 10.1007/s11920-022-01385-6.Peer-Reviewed Original ResearchConceptsAnxiety disordersError Related NegativityPediatric anxiety disordersMost anxiety disordersDisorder treatment outcomesAnxious individualsNeural correlatesMultimodal integrationNeural markersGroup differencesResponse/outcomesAnxietyMultimodal dataCorrelatesTreatment responseTreatment outcomesDiverse relationsDisordersReviewThis reviewNegativityRecent FindingsRecent literatureRisk markersAdulthoodSuch workOutcomesShared brain and genetic architectures between mental health and physical activity
Zhang W, Paul S, Winkler A, Bogdan R, Bijsterbosch J. Shared brain and genetic architectures between mental health and physical activity. Translational Psychiatry 2022, 12: 428. PMID: 36192376, PMCID: PMC9530213, DOI: 10.1038/s41398-022-02172-w.Peer-Reviewed Original ResearchConceptsPhysical activityMental healthConnectivity strengthPhysical activity measuresSelf-reported mental health measuresMental health measuresPhysical activity modelBrain network architectureLatent causal variable analysisAccelerometer-derived measuresHealth measuresActivity measuresBeneficial effectsBiological correlatesUK BiobankCausal relationshipBrain mechanismsNeural correlatesHealthLinkage disequilibrium score regressionSimilar loading patternsBrainPutative causal relationshipDisequilibrium score regressionForms of psychopathology
2021
Recent advances in understanding neural correlates of anxiety disorders in children and adolescents
Zugman A, Winkler A, Pine D. Recent advances in understanding neural correlates of anxiety disorders in children and adolescents. Current Opinion In Psychiatry 2021, 34: 617-623. PMID: 34475352, PMCID: PMC8490291, DOI: 10.1097/yco.0000000000000743.Peer-Reviewed Original ResearchConceptsAnxiety disordersBrain regionsMedial prefrontal cortexNeural indicesLow-level threatNeural correlatesSmall effect sizesPrefrontal cortexNeural circuitryBrain circuitryCircuitry dysfunctionBrain connectivityCommon psychiatric diagnosesFearEffect sizeMost mental illnessesStria terminalisBed nucleusAnxietyAdolescentsPsychiatric diagnosisMental illnessRecent workDisordersChildren