P.1.028 Persistent reduction in brain 5-HT1A receptorbinding in recovered depressed men using positron emission tomography and [11C]WAY-100835
Bhagwagar Z, Rabiner E, Sargente R, Grasby P, Cowen P. P.1.028 Persistent reduction in brain 5-HT1A receptorbinding in recovered depressed men using positron emission tomography and [11C]WAY-100835. European Neuropsychopharmacology 2004, 14: s185. DOI: 10.1016/s0924-977x(04)80117-2.Peer-Reviewed Original ResearchPersistent reduction in brain serotonin1A receptor binding in recovered depressed men measured by positron emission tomography with [11C]WAY-100635
Bhagwagar Z, Rabiner E, Sargent P, Grasby P, Cowen P. Persistent reduction in brain serotonin1A receptor binding in recovered depressed men measured by positron emission tomography with [11C]WAY-100635. Molecular Psychiatry 2004, 9: 386-392. PMID: 15042104, DOI: 10.1038/sj.mp.4001401.Peer-Reviewed Original ResearchConceptsMajor depressionDepressed menDepressed subjectsAcute major depressionPositron emission tomography studyPotentials of brainEmission tomography studiesRecurrent major depressionPositron emission tomographyStatistical parametric mappingReceptor BPReference tissue modelAntidepressant medicationPersistent dysfunctionRaphe nucleusUnmedicated subjectsHealthy controlsBP valuesCortical areasTrait abnormalityMale subjectsEmission tomographyPersistent reductionTomography studyReceptor binding