2005
Lamotrigine in the treatment of bipolar disorder
Bhagwagar Z, Goodwin G. Lamotrigine in the treatment of bipolar disorder. Expert Opinion On Pharmacotherapy 2005, 6: 1401-1408. PMID: 16013989, DOI: 10.1517/14656566.6.8.1401.Peer-Reviewed Original ResearchConceptsBipolar disorderIncidence of rashCommon side effectsLong-term treatmentTreatment of epilepsyCareful prescribingPivotal trialsNovel anticonvulsant agentGlutamatergic functionMood disordersSide effectsPsychiatric conditionsAnticonvulsant agentsMode of actionIon channel conductanceDisordersLamotrigineLong-term basisTreatmentEfficacyPlaceboRashPrescribingHeadachePatients
2002
The role of lithium in the treatment of bipolar depression
Bhagwagar Z, Goodwin G. The role of lithium in the treatment of bipolar depression. Clinical Neuroscience Research 2002, 2: 222-227. DOI: 10.1016/s1566-2772(02)00046-4.Peer-Reviewed Original Research
2001
Pindolol Augmentation of Selective Serotonin Reuptake Inhibitors: PET Evidence That the Dose Used in Clinical Trials Is Too Low
Rabiner E, Bhagwagar Z, Gunn R, Sargent P, Bench C, Cowen P, Grasby P. Pindolol Augmentation of Selective Serotonin Reuptake Inhibitors: PET Evidence That the Dose Used in Clinical Trials Is Too Low. American Journal Of Psychiatry 2001, 158: 2080-2082. PMID: 11729033, DOI: 10.1176/appi.ajp.158.12.2080.Peer-Reviewed Original ResearchMeSH KeywordsAdultBrainDepressive Disorder, MajorDose-Response Relationship, DrugDrug Administration ScheduleDrug Therapy, CombinationFemaleHumansMaleMiddle AgedPindololReceptors, SerotoninReceptors, Serotonin, 5-HT1Selective Serotonin Reuptake InhibitorsTomography, Emission-ComputedTreatment OutcomeConceptsPositron emission tomographyDose of pindololClinical trialsDepressed patientsSelective serotonin reuptake inhibitorsSignificant occupancyPresent clinical trialSerotonin reuptake inhibitorsPindolol augmentationAntidepressant medicationReuptake inhibitorsPET evidenceEmission tomographyPindololTrialsDoseAutoreceptorsMedicationsPatientsInconsistent resultsEfficacyVast majorityDoses