2024
ODD: A Benchmark Dataset for the Natural Language Processing Based Opioid Related Aberrant Behavior Detection.
Kwon S, Wang X, Liu W, Druhl E, Sung M, Reisman J, Li W, Kerns R, Becker W, Yu H. ODD: A Benchmark Dataset for the Natural Language Processing Based Opioid Related Aberrant Behavior Detection. Annual Meeting 2024, 2024: 4338-4359. PMID: 39224833, PMCID: PMC11368170.Peer-Reviewed Original ResearchBenchmark datasetsState-of-the-art natural language processing modelsNatural language processing modelsState-of-the-artLanguage processing modelsAberrant behaviorDetection datasetMacro-average areaBehavior detectionPrecision recall curveDiagnosed opioid dependencePerformance improvementRecall curveDatasetProcess modelExperimental resultsCentral nervous system-relatedOpioid dependenceNervous system-relatedMedication changesOpioidBenchmarks
2023
Are opioids effective analgesics and is physiological opioid dependence benign? Revising current assumptions to effectively manage long‐term opioid therapy and its deprescribing
Manhapra A, MacLean R, Rosenheck R, Becker W. Are opioids effective analgesics and is physiological opioid dependence benign? Revising current assumptions to effectively manage long‐term opioid therapy and its deprescribing. British Journal Of Clinical Pharmacology 2023 PMID: 37990580, PMCID: PMC11563311, DOI: 10.1111/bcp.15972.Peer-Reviewed Original ResearchLong-term opioid therapyOpioid therapyFunctional gainsChronic pain syndromeMaximum functional recoveryOngoing opioid crisisParadoxical worseningAnalgesic benefitAnalgesic therapyPain reliefPain syndromeEffective analgesicMost patientsAntinociceptive effectAntinociceptive systemChronic painFunctional recoveryOpioid actionOpioid dependenceMedical instabilityFunctional improvementPlacebo effectClinical principlesOpioid crisisTherapeutic induction