Brain–phenotype models fail for individuals who defy sample stereotypes
Greene AS, Shen X, Noble S, Horien C, Hahn CA, Arora J, Tokoglu F, Spann MN, Carrión CI, Barron DS, Sanacora G, Srihari VH, Woods SW, Scheinost D, Constable RT. Brain–phenotype models fail for individuals who defy sample stereotypes. Nature 2022, 609: 109-118. PMID: 36002572, PMCID: PMC9433326, DOI: 10.1038/s41586-022-05118-w.Peer-Reviewed Original ResearchConceptsBrain-phenotype relationshipsBrain functional organizationCognitive constructsIndividual differencesNeurocognitive measuresBrain activityNeurocognitive scoresStereotypical profileNeural targetsClinical interventionsNeural circuitsFunctional organizationIndividualsSuch relationshipsData-driven approachRelationshipStereotypes