2024
Structural white matter abnormalities in Schizophrenia and associations with neurocognitive performance and symptom severity
Male A, Goudzwaard E, Nakahara S, Turner J, Calhoun V, Mueller B, Lim K, Bustillo J, Belger A, Voyvodic J, O'Leary D, Mathalon D, Ford J, Potkin S, Preda A, van Erp T. Structural white matter abnormalities in Schizophrenia and associations with neurocognitive performance and symptom severity. Psychiatry Research Neuroimaging 2024, 342: 111843. PMID: 38896909, DOI: 10.1016/j.pscychresns.2024.111843.Peer-Reviewed Original ResearchConceptsSymptom severityFractional anisotropyDiffusion tensor imagingNeurocognitive performanceCognitive performanceAssociated with speed of processingLeft inferior fronto-occipital fasciculusWM abnormalitiesAssociated with neurocognitive performancePathophysiology of schizophreniaCognitive performance deficitsInferior fronto-occipital fasciculusSpeed of processingStructural white matter abnormalitiesMean diffusivityAxial diffusivityFronto-occipital fasciculusHealthy controlsRadial diffusivityRegional WM abnormalitiesNegative symptomsPerformance deficitsWhite matterWhite matter abnormalitiesAssociated with speed
2023
Symmetric data-driven fusion of diffusion tensor MRI: Age differences in white matter
Colmenares A, Hefner M, Calhoun V, Salerno E, Fanning J, Gothe N, McAuley E, Kramer A, Burzynska A. Symmetric data-driven fusion of diffusion tensor MRI: Age differences in white matter. Frontiers In Neurology 2023, 14: 1094313. PMID: 37139071, PMCID: PMC10149813, DOI: 10.3389/fneur.2023.1094313.Peer-Reviewed Original ResearchDiffusion tensor imagingAge differencesExamination of age differencesPattern of age differencesFractional anisotropyRadial diffusivityJoint independent component analysisCognitively healthy adultsWhite matterDiffusion tensor imaging parametersFluid abilitiesPrefrontal WMProcessing speedDiagnostic classificationWM pathologyDiffusion tensor imaging datasetsAging WMUnimodal analysisTensor imagingIndependent component analysisClinical samplesHealthy agingCognitionCorpus callosumHealthy adults