Interplay between preclinical indices of obesity and neural signatures of fluid intelligence in youth
Ward T, Schantell M, Dietz S, Ende G, Rice D, Coutant A, Arif Y, Wang Y, Calhoun V, Stephen J, Heinrichs-Graham E, Taylor B, Wilson T. Interplay between preclinical indices of obesity and neural signatures of fluid intelligence in youth. Communications Biology 2024, 7: 1285. PMID: 39379610, PMCID: PMC11461743, DOI: 10.1038/s42003-024-06924-w.Peer-Reviewed Original ResearchConceptsAbstract reasoning taskFluid intelligenceAbstract reasoningBrain regionsNeural activityReasoning tasksLeft dorsolateral prefrontal cortexLeft temporoparietal junctionDorsolateral prefrontal cortexHigher-order cognitionWhole-brain correlationHigh-density magnetoencephalographySignificant oscillatory responsesYouth aged 9Prefrontal cortexTemporoparietal junctionNeural signaturesTheta oscillationsResponse scaleWhole-brainNeurobehavioral functionNeural dynamicsAged 9CognitionReaction timeSexual dimorphism in cortical theta rhythms relates to elevated internalizing symptoms during adolescence
Petro N, Picci G, Ott L, Rempe M, Embury C, Penhale S, Wang Y, Stephen J, Calhoun V, Taylor B, Wilson T. Sexual dimorphism in cortical theta rhythms relates to elevated internalizing symptoms during adolescence. Imaging Neuroscience 2024, 2: 1-13. DOI: 10.1162/imag_a_00062.Peer-Reviewed Original ResearchSpontaneous neural activityInternalizing symptomsNeural activityPsychiatric disordersEmergence of psychiatric disordersTheta activityEmergence of psychiatric symptomsAbstract Psychiatric disordersElevated internalizing symptomsStructural brain differencesTypically-developing youthSpontaneous theta activityEyes-closed restTheta frequency bandNegative ruminationCingulate cortexTemporoparietal junctionBrain differencesExternalizing symptomsPsychiatric symptomsAssociation cortexCortical regionsSex differencesCortical activityAssociation regionsApplication of hyperalignment to resting state data in individuals with psychosis reveals systematic changes in functional networks and identifies distinct clinical subgroups
Anderson Z, Turner J, Ashar Y, Calhoun V, Mittal V. Application of hyperalignment to resting state data in individuals with psychosis reveals systematic changes in functional networks and identifies distinct clinical subgroups. Aperture Neuro 2024, 4 DOI: 10.52294/001c.91992.Peer-Reviewed Original ResearchFrontal connectivityPsychosis groupBaseline connectivityResting state functional connectivityPatterns of neural activitySubgroups of psychosisBrain-based biomarkersSample of individualsResting state dataBrain dataFollow-up analysisPsychosis symptomsFrontal cortexIndividual differencesFunctional connectivityPsychosisClinical populationsDiagnostic categoriesNeural activityClinical subpopulationsNetwork topographyClinically relevant differencesFunctional networksRelated disordersHealthy controls