F71. NETWORK OF CO-METHYLATION ASSOCIATED WITH GREY MATTER MATURATION IN HUMAN ADOLESCENCE
Jensen D, Chen J, Turner J, Stephen J, Wang Y, Wilson T, Calhoun V, Liu J. F71. NETWORK OF CO-METHYLATION ASSOCIATED WITH GREY MATTER MATURATION IN HUMAN ADOLESCENCE. European Neuropsychopharmacology 2023, 75: s258-s259. DOI: 10.1016/j.euroneuro.2023.08.455.Peer-Reviewed Original ResearchStructural MRIBrain maturationNeuronal systemsCo-methylation network analysisPeriod of brain maturationAdolescent brain developmentAdolescent brain maturationPhases of neurodevelopmentIndependent component analysisGray matterHuman brain structureGM maturationDNAm changesCo-methylation modulesPrefrontal cortexExecutive functionFrontal poleGM volumeTime pointsSubjects aged 9Brain structuresCpG sitesSynaptic pruningBrain developmentDNA methylationAuditory oddball hypoactivation in schizophrenia
Nakahara S, Male A, Turner J, Calhoun V, Lim K, Mueller B, Bustillo J, O'Leary D, Voyvodic J, Belger A, Preda A, Mathalon D, Ford J, Guffanti G, Macciardi F, Potkin S, Van Erp T. Auditory oddball hypoactivation in schizophrenia. Psychiatry Research Neuroimaging 2023, 335: 111710. PMID: 37690161, DOI: 10.1016/j.pscychresns.2023.111710.Peer-Reviewed Original ResearchConceptsSchizophrenia polygenic risk scoresFunctional magnetic resonance imagingPolygenic risk scoresCognitive performanceOddball targetsAssociated with cognitive performanceRight supramarginal cortexCognitive domain performanceBrain imaging studiesAuditory oddball taskPrecuneus activationSchizophrenia individualsFrontal poleSchizophreniaOddball taskBrain activityRight thalamusHippocampal cortexRegional activityHypoactivationSample 2Sample 1PrecuneusHealthy volunteersCross-sectional data sets